Regular boosters stimulate #Tcellmemory, leading to a stable & enhanced immune response that may provide better protection against symptomatic infections. In addition, repeated vaccinations in cases associated with presumed asymptomatic infections

#Tcellmemory has been observed to persist for at least 6–12 mths, some studies report functional exhaustion of CD4+ T cells after 1 year
- Comparison with Other Coronaviruses: Studies on #SARSCoV1 & T cell memory can last for several years as long lasting #Tcell responses are suggested for #SARSCoV2

What if memory T cells don't need antigen re-exposure to persist? Could this reshape vaccines and treatments? What do you think determines long-term T cell memory without ongoing antigen stimulation? Read more: https://www.nature.com/articles/nri.2015.1 #Immunology #TcellMemory