Absolutely fascinating story showing different functions for CD4 vs CD8 regulatory cells in humoral immunity and the role of Foxp3 vs Granzyme B. #ImmunoSky #GCBcellSky #TfhSky
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Differential roles of human CD4+ and CD8+ regulatory T cells in controlling self-reactive immune responses - Nature Immunology
Here the authors use a tonsil organoid culture model system to investigate the roles of human CD4+ and CD8+ regulatory T cells in controlling self-reactive immune responses. CD4+ regulatory T cells we...
www.nature.com
February 1, 2025 at 4:37 PM
Absolutely fascinating story showing different functions for CD4 vs CD8 regulatory cells in humoral immunity and the role of Foxp3 vs Granzyme B. #ImmunoSky #GCBcellSky #TfhSky
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Interesting study on how high affinity B cells expand well after getting stimulated by TFH cells in the GC. My main beef is they keep referring to proliferating activated B cells-- what I would call plasmablasts-- as plasma cells! Weird. #ImmunoSky #GCSky #TfhSky
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Affinity maturation of antibody responses is mediated by differential plasma cell proliferation
Increased antibody affinity over time after vaccination, known as affinity maturation, is a prototypical feature of immune responses. Recent studies have shown that a diverse collection of B cells, pr...
www.science.org
January 24, 2025 at 6:40 PM
Interesting study on how high affinity B cells expand well after getting stimulated by TFH cells in the GC. My main beef is they keep referring to proliferating activated B cells-- what I would call plasmablasts-- as plasma cells! Weird. #ImmunoSky #GCSky #TfhSky
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...