#TheColonnaLab
Incredible! Over the past 2 months, 5 independent manuscripts — from @TheColonnaLab, Dan Littman, @gardnerlabucsf.bsky.social and @chrysothemisbrown.bsky.social , and our own (now in @nature.com, www.nature.com/articles/s41...), reports that the dietary pTreg program is initiated by RORγt⁺ APCs. /1
May 27, 2025 at 6:50 PM
Macrophages near brain blood vessels regulate blood flow & waste clearance to protect against Alzheimers. #TheColonnaLab reports cMAF enables this key signaling.
Congrats to Dr. Colonna! @washumedicine.bsky.social @mgbresearch.bsky.social h.bsky.social
Brain perivascular macrophages regulate endothelial cell function via a cMAF-dependent transcriptional program in mouse and human
This study identifies cMAF as a key transcription factor that orchestrates the molecular crosstalk between brain perivascular macrophages and arteries, thereby sustaining cerebrovascular function in h...
www.cell.com
August 14, 2026 at 5:36 PM