Nascent transcription profiling identifies H3K36 methylation as a custodian of the somatic transcriptome
#Drosophila
#Drosophila
Nascent transcription profiling identifies H3K36 methylation as a custodian of the somatic transcriptome
#Drosophila
PubMed link
pubmed.ncbi.nlm.nih.gov
November 6, 2026 at 5:23 PM
Nascent transcription profiling identifies H3K36 methylation as a custodian of the somatic transcriptome
#Drosophila
#Drosophila
Moving beyond reporter editing, we targeted the mutant human protein HTT in an aggressive mouse model of Huntington’s disease. PERCEPT reduced pathogenic protein aggregates and shifted local gene expression away from the typical inflammatory and injury-associated transcriptome.
November 6, 2026 at 1:56 PM
Moving beyond reporter editing, we targeted the mutant human protein HTT in an aggressive mouse model of Huntington’s disease. PERCEPT reduced pathogenic protein aggregates and shifted local gene expression away from the typical inflammatory and injury-associated transcriptome.
Transcriptome reallocation during infection reshapes synonymous codon demand in Botrytis cinerea https://www.biorxiv.org/content/10.64898/2026.11.04.764316v1
November 6, 2026 at 12:34 PM
Transcriptome reallocation during infection reshapes synonymous codon demand in Botrytis cinerea https://www.biorxiv.org/content/10.64898/2026.11.04.764316v1
Transcriptome reallocation during infection reshapes synonymous codon demand in Botrytis cinerea https://www.biorxiv.org/content/10.64898/2026.11.04.764316v1
November 6, 2026 at 12:34 PM
Transcriptome reallocation during infection reshapes synonymous codon demand in Botrytis cinerea https://www.biorxiv.org/content/10.64898/2026.11.04.764316v1
Only a few places are available on Bulk RNA-seq analysis (online) on 25 Nov, 2, 4 Dec.
Participants will learn about quality control, alignment, and quantification of gene expression against a reference transcriptome.
Book here 👇️️️️
cambiotraining.github.io/events/?cour...
Participants will learn about quality control, alignment, and quantification of gene expression against a reference transcriptome.
Book here 👇️️️️
cambiotraining.github.io/events/?cour...
November 6, 2026 at 11:04 AM
Only a few places are available on Bulk RNA-seq analysis (online) on 25 Nov, 2, 4 Dec.
Participants will learn about quality control, alignment, and quantification of gene expression against a reference transcriptome.
Book here 👇️️️️
cambiotraining.github.io/events/?cour...
Participants will learn about quality control, alignment, and quantification of gene expression against a reference transcriptome.
Book here 👇️️️️
cambiotraining.github.io/events/?cour...
Claustrum Transcriptome Alterations in Schizophrenia jamanetwork.com/journals/jam...
Claustrum Transcriptome Alterations in Schizophrenia
This case-control study investigates schizophrenia-associated transcriptome alterations in the dorsal claustrum.
jamanetwork.com
November 6, 2026 at 2:57 AM
Claustrum Transcriptome Alterations in Schizophrenia jamanetwork.com/journals/jam...
Single-Cell Transcriptome-Wide Mendelian Randomization and Colocalization Analysis Reveals Immune Cell-Specific Mechanisms in Alzheimer's Disease #NeuroDegeneration 🧪🧠
https://www.medrxiv.org/content/10.64898/2026.11.03.26367234v1
https://www.medrxiv.org/content/10.64898/2026.11.03.26367234v1
November 6, 2026 at 2:01 AM
Single-Cell Transcriptome-Wide Mendelian Randomization and Colocalization Analysis Reveals Immune Cell-Specific Mechanisms in Alzheimer's Disease #NeuroDegeneration 🧪🧠
https://www.medrxiv.org/content/10.64898/2026.11.03.26367234v1
https://www.medrxiv.org/content/10.64898/2026.11.03.26367234v1
Single-Cell Transcriptome-Wide Mendelian Randomization and Colocalization Analysis Reveals Immune Cell-Specific Mechanisms in Alzheimer's Disease #SingleCell 🧪🧬🖥️
https://www.medrxiv.org/content/10.64898/2026.11.03.26367234v1
https://www.medrxiv.org/content/10.64898/2026.11.03.26367234v1
November 6, 2026 at 2:00 AM
Single-Cell Transcriptome-Wide Mendelian Randomization and Colocalization Analysis Reveals Immune Cell-Specific Mechanisms in Alzheimer's Disease #SingleCell 🧪🧬🖥️
https://www.medrxiv.org/content/10.64898/2026.11.03.26367234v1
https://www.medrxiv.org/content/10.64898/2026.11.03.26367234v1
Transcriptome work on the claustrum in schizophrenia sounds fascinating given its role in consciousness. What stood out most from the interview?
November 6, 2026 at 1:30 AM
Transcriptome work on the claustrum in schizophrenia sounds fascinating given its role in consciousness. What stood out most from the interview?
JAMA Psychiatry Author Interviews
Claustrum Transcriptome Alterations in Schizophrenia
JAMA Psychiatry Author Interviews · Episode
open.spotify.com
November 6, 2026 at 12:31 AM
JAMA Psychiatry Author Interviews
Minchun Chen and I wrote this Preview out today in @cp-molcell.bsky.social
"Hidden diversity from transposable element RNAs in cancer"
authors.elsevier.com/a/1o3Ng3vVUP...
For this article
www.sciencedirect.com/science/arti...
on the gene-independent TE transcriptome (TEtrans) in cancer.
"Hidden diversity from transposable element RNAs in cancer"
authors.elsevier.com/a/1o3Ng3vVUP...
For this article
www.sciencedirect.com/science/arti...
on the gene-independent TE transcriptome (TEtrans) in cancer.
November 5, 2026 at 11:10 PM
Minchun Chen and I wrote this Preview out today in @cp-molcell.bsky.social
"Hidden diversity from transposable element RNAs in cancer"
authors.elsevier.com/a/1o3Ng3vVUP...
For this article
www.sciencedirect.com/science/arti...
on the gene-independent TE transcriptome (TEtrans) in cancer.
"Hidden diversity from transposable element RNAs in cancer"
authors.elsevier.com/a/1o3Ng3vVUP...
For this article
www.sciencedirect.com/science/arti...
on the gene-independent TE transcriptome (TEtrans) in cancer.
✨Blood Transcriptome and Serum Protein Biomarkers Associated with Tophaceous Gout – Austin Wheeler UNMC
STOP Gout trial - 48wk timepoint
No peripheral biomarkers were diff wrt tophus status
Bulk RNA sequencing & pathway enrichment - clustered around innate immune pathways
#2026GCAN #ACR26
STOP Gout trial - 48wk timepoint
No peripheral biomarkers were diff wrt tophus status
Bulk RNA sequencing & pathway enrichment - clustered around innate immune pathways
#2026GCAN #ACR26
November 5, 2026 at 9:18 PM
Bioinformatics perspectives on transcriptomics: A comprehensive review of bulk and single-cell RNA sequencing analyses.
A comprehensive review of bioinformatics approaches for analyzing bulk and single-cell RNA-seq data.
doi.org/10.1002/qub2...
A comprehensive review of bioinformatics approaches for analyzing bulk and single-cell RNA-seq data.
doi.org/10.1002/qub2...
Bioinformatics perspectives on transcriptomics: A comprehensive review of bulk and single‐cell RNA sequencing analyses
The transcriptome, the complete set of RNA molecules within a cell, plays a critical role in regulating physiological processes. The advent of RNA sequencing (RNA-seq) facilitated by Next Generation ...
doi.org
November 5, 2026 at 7:29 PM
Bioinformatics perspectives on transcriptomics: A comprehensive review of bulk and single-cell RNA sequencing analyses.
A comprehensive review of bioinformatics approaches for analyzing bulk and single-cell RNA-seq data.
doi.org/10.1002/qub2...
A comprehensive review of bioinformatics approaches for analyzing bulk and single-cell RNA-seq data.
doi.org/10.1002/qub2...
Whole Transcriptome Sequencing Reveals a GATA4-INHA Program and Progenitor Cell of Origin in Cholangioblastic Cholangiocarcinoma
@modernpathology.bsky.social
Read More: buff.ly/XJOhH2C
@modernpathology.bsky.social
Read More: buff.ly/XJOhH2C
November 5, 2026 at 7:03 PM
Whole Transcriptome Sequencing Reveals a GATA4-INHA Program and Progenitor Cell of Origin in Cholangioblastic Cholangiocarcinoma
@modernpathology.bsky.social
Read More: buff.ly/XJOhH2C
@modernpathology.bsky.social
Read More: buff.ly/XJOhH2C
The 'shape' of gene expression:
Identifying genes that may share roles across species
Geometric inference of cross-species transcriptome correspondence🧪
www.cell.com/cell-reports...
Identifying genes that may share roles across species
Geometric inference of cross-species transcriptome correspondence🧪
www.cell.com/cell-reports...
November 5, 2026 at 5:01 PM
The 'shape' of gene expression:
Identifying genes that may share roles across species
Geometric inference of cross-species transcriptome correspondence🧪
www.cell.com/cell-reports...
Identifying genes that may share roles across species
Geometric inference of cross-species transcriptome correspondence🧪
www.cell.com/cell-reports...
Resolving the immune response across clonal cancer evolution in situ with Atera whole transcriptome profiling #SingleCell 🧪🧬🖥️
https://www.researchsquare.com/article/rs-10911194/latest
https://www.researchsquare.com/article/rs-10911194/latest
November 5, 2026 at 8:01 AM
Resolving the immune response across clonal cancer evolution in situ with Atera whole transcriptome profiling #SingleCell 🧪🧬🖥️
https://www.researchsquare.com/article/rs-10911194/latest
https://www.researchsquare.com/article/rs-10911194/latest
* Democratizing Ribo-seq: RAPPL-seq*
RAPPL-seq allows robust and high-efficiency Ribo-seq by substantially improving ribosome recovery
www.biorxiv.org/content/10.6...
After developing a fast and robust method to isolate ribosomes, RAPPL:
www.nature.com/articles/s41...
RAPPL-seq allows robust and high-efficiency Ribo-seq by substantially improving ribosome recovery
www.biorxiv.org/content/10.6...
After developing a fast and robust method to isolate ribosomes, RAPPL:
www.nature.com/articles/s41...
RAPPL-Seq Enables Rapid, High-Sensitivity Ribosome Profiling of Scarce Samples
Ribosome profiling is a powerful method for transcriptome-wide monitoring of translation activity in vivo , but its use is limited by lengthy protocols, reliance on specialized equipment and inefficie...
www.biorxiv.org
November 5, 2026 at 7:31 AM
* Democratizing Ribo-seq: RAPPL-seq*
RAPPL-seq allows robust and high-efficiency Ribo-seq by substantially improving ribosome recovery
www.biorxiv.org/content/10.6...
After developing a fast and robust method to isolate ribosomes, RAPPL:
www.nature.com/articles/s41...
RAPPL-seq allows robust and high-efficiency Ribo-seq by substantially improving ribosome recovery
www.biorxiv.org/content/10.6...
After developing a fast and robust method to isolate ribosomes, RAPPL:
www.nature.com/articles/s41...
Jiaqi Xiong, Jiaying Li, Yu Zheng, Xiang Zhou, Ziteng Wang, Xinting Hu, Jiaxin Qi: Rethinking One Gene, One Token: Transcriptome-Aware Tokenization for Single-Cell Foundation Models https://arxiv.org/abs/2611.05410 https://arxiv.org/pdf/2611.05410 https://arxiv.org/html/2611.05410
November 5, 2026 at 6:59 AM
Jiaqi Xiong, Jiaying Li, Yu Zheng, Xiang Zhou, Ziteng Wang, Xinting Hu, Jiaxin Qi: Rethinking One Gene, One Token: Transcriptome-Aware Tokenization for Single-Cell Foundation Models https://arxiv.org/abs/2611.05410 https://arxiv.org/pdf/2611.05410 https://arxiv.org/html/2611.05410
Rethinking One Gene, One Token: Transcriptome-Aware Tokenization for Single-Cell Foundation Models #SingleCell 🧪🧬🖥️
https://arxiv.org/abs/2611.05410
https://arxiv.org/abs/2611.05410
November 5, 2026 at 5:00 AM
Rethinking One Gene, One Token: Transcriptome-Aware Tokenization for Single-Cell Foundation Models #SingleCell 🧪🧬🖥️
https://arxiv.org/abs/2611.05410
https://arxiv.org/abs/2611.05410
A conserved thermodynamic signature links transcriptome organization to growth state https://www.biorxiv.org/content/10.64898/2026.11.03.764118v1
November 4, 2026 at 10:47 PM
A conserved thermodynamic signature links transcriptome organization to growth state https://www.biorxiv.org/content/10.64898/2026.11.03.764118v1
A conserved thermodynamic signature links transcriptome organization to growth state https://www.biorxiv.org/content/10.64898/2026.11.03.764118v1
November 4, 2026 at 10:47 PM
A conserved thermodynamic signature links transcriptome organization to growth state https://www.biorxiv.org/content/10.64898/2026.11.03.764118v1
Get the guide! The Single-Cell Technology Landscape. www.missionbio.com/resources/eb...
The Single-Cell Technology Landscape | Mission Bio
Compare 19 single-cell method families across genome, epigenome, transcriptome, proteome, spatial, and multiomics, and learn how to choose the right one.
www.missionbio.com
November 4, 2026 at 6:18 PM
Get the guide! The Single-Cell Technology Landscape. www.missionbio.com/resources/eb...
RNA accessibility sequencing reveals transcriptome-wide RBP binding and RNA structure https://www.biorxiv.org/content/10.64898/2026.11.02.763788v1
November 4, 2026 at 8:46 AM
RNA accessibility sequencing reveals transcriptome-wide RBP binding and RNA structure https://www.biorxiv.org/content/10.64898/2026.11.02.763788v1
RNA accessibility sequencing reveals transcriptome-wide RBP binding and RNA structure https://www.biorxiv.org/content/10.64898/2026.11.02.763788v1
November 4, 2026 at 8:46 AM
RNA accessibility sequencing reveals transcriptome-wide RBP binding and RNA structure https://www.biorxiv.org/content/10.64898/2026.11.02.763788v1