One of my sons has started watching #F1 again which means I have to watch it. #USGrandPrix has ended like all the others he forced me to watch. Virtual Safety Car & slow procession of boredom.
#skyf1 #USF1
#skyf1 #USF1
October 25, 2026 at 9:42 PM
One of my sons has started watching #F1 again which means I have to watch it. #USGrandPrix has ended like all the others he forced me to watch. Virtual Safety Car & slow procession of boredom.
#skyf1 #USF1
#skyf1 #USF1
Lyrics from: Front 242 ~ Headhunter V1.0
YouTube video by Underrated Artists United
www.youtube.com
September 10, 2026 at 11:11 AM
Died 2010 born 2026 welcome back USF1
The Cadillac F1 team being a one and done program will be the most American F1 thing ever
August 14, 2026 at 2:45 AM
Died 2010 born 2026 welcome back USF1
Need to get @theracetool to make more videos ;) RT @marshallpruett Curious if production of the USF1 Toasters can be ramped up
November 22, 2024 at 5:17 PM
Need to get @theracetool to make more videos ;) RT @marshallpruett Curious if production of the USF1 Toasters can be ramped up
November 22, 2024 at 3:42 PM
November 22, 2024 at 3:29 PM
So was anyone amused at the blatant plug Varsha gave Windsor about USF1. We are thinking this might just be a SpeedTV ploy
November 22, 2024 at 2:37 PM
So was anyone amused at the blatant plug Varsha gave Windsor about USF1. We are thinking this might just be a SpeedTV ploy
The USR is extremely conserved, it is an IDR and it works as a context-dependent TAD. To validate the structural observations we designed serially deleted constructs of USF1. With complete, partial and totally deleted USR.
November 10, 2024 at 7:27 PM
The USR is extremely conserved, it is an IDR and it works as a context-dependent TAD. To validate the structural observations we designed serially deleted constructs of USF1. With complete, partial and totally deleted USR.
EMSAs and structural data suggested that an extended region from USF1, upstream of its DNA-binding domain (DBD), could mediate contacts with NF-Y globular core. Protein disorder analyses predicted a long #IDR that includes the so-called USF-specific region (USR).
November 10, 2024 at 7:27 PM
EMSAs and structural data suggested that an extended region from USF1, upstream of its DNA-binding domain (DBD), could mediate contacts with NF-Y globular core. Protein disorder analyses predicted a long #IDR that includes the so-called USF-specific region (USR).
We isolated ternary complexes and our collaborators made some nice molecular models starting from #SAXS datasets. The scattering data are compatible with a direct protein-protein interaction between the two TFs on DNA. This seems to be mediated by an extended region of USF1 dimer.
November 10, 2024 at 7:27 PM
We isolated ternary complexes and our collaborators made some nice molecular models starting from #SAXS datasets. The scattering data are compatible with a direct protein-protein interaction between the two TFs on DNA. This seems to be mediated by an extended region of USF1 dimer.
We then removed USF1 1st transactivation domain (TAD1) and all the NF-Y domains outside the conserved core region. Result: DNA-binding cooperativity is fully maintained. Those regions are dispensable.
November 10, 2024 at 7:27 PM
We then removed USF1 1st transactivation domain (TAD1) and all the NF-Y domains outside the conserved core region. Result: DNA-binding cooperativity is fully maintained. Those regions are dispensable.
NF-Y is a fascinating #pioneer, #histone-like, heterotrimeric TF, while USF1/2 are members of the basic-Helix-loop-Helix (bHLH) TFs, such as MYC.
November 10, 2024 at 7:27 PM
NF-Y is a fascinating #pioneer, #histone-like, heterotrimeric TF, while USF1/2 are members of the basic-Helix-loop-Helix (bHLH) TFs, such as MYC.
Genome-wide observations from our lab and others showed a striking positional bias of 10/12 bp between motifs occupied by the two TFs NF-Y (CCAAT box) and USF1/2 (E-box, CACGTG) in subsets of promoters and specific subgroups of retroviral elements #LTRs. doi.org/10.1371/jour...
November 10, 2024 at 7:27 PM
Genome-wide observations from our lab and others showed a striking positional bias of 10/12 bp between motifs occupied by the two TFs NF-Y (CCAAT box) and USF1/2 (E-box, CACGTG) in subsets of promoters and specific subgroups of retroviral elements #LTRs. doi.org/10.1371/jour...
USF1 considered hiring Kyle Busch, Haas hired Kurt Busch, Cadillac is signing Sophia Bush. Clearly the easiest way to be hired by an American owned F1 team is to be named after a shrub
May 4, 2025 at 12:10 AM
USF1 considered hiring Kyle Busch, Haas hired Kurt Busch, Cadillac is signing Sophia Bush. Clearly the easiest way to be hired by an American owned F1 team is to be named after a shrub
"see if Cadillac's F1 adventure turns out to be as glorious as the moment American astronauts planted their flag on the Moon" yeah I'll put a bet on USF1 over that happening lol. like what in the glazing
March 7, 2026 at 1:55 AM
"see if Cadillac's F1 adventure turns out to be as glorious as the moment American astronauts planted their flag on the Moon" yeah I'll put a bet on USF1 over that happening lol. like what in the glazing
Andretti: building a state of the art facility specifically to house a new F1 operation, backed by a company with 60B and General Motors.
USF1: what if we used the old Joe Gibbs Racing facility in 2009 to build F1 cars during a global recession with no manufacturer support?
USF1: what if we used the old Joe Gibbs Racing facility in 2009 to build F1 cars during a global recession with no manufacturer support?
November 3, 2023 at 6:31 PM
Andretti: building a state of the art facility specifically to house a new F1 operation, backed by a company with 60B and General Motors.
USF1: what if we used the old Joe Gibbs Racing facility in 2009 to build F1 cars during a global recession with no manufacturer support?
USF1: what if we used the old Joe Gibbs Racing facility in 2009 to build F1 cars during a global recession with no manufacturer support?
Considering Gainbridge is financing this and GM is providing equipment it's nothing like Peter Windsor USF1 hand wank.
You meant to say McLaren-Honda. Top tier organization with backmarker performance.
You meant to say McLaren-Honda. Top tier organization with backmarker performance.
November 3, 2023 at 6:05 PM
Considering Gainbridge is financing this and GM is providing equipment it's nothing like Peter Windsor USF1 hand wank.
You meant to say McLaren-Honda. Top tier organization with backmarker performance.
You meant to say McLaren-Honda. Top tier organization with backmarker performance.
@thermofishersci.bsky.social's resource, RRID:AB_10853811, was just reported to be used in the paper. We value the author's support of reproducibility. #methodsmatter #accelerateopenscience #reproducibility
EFO2 promotes triple-negative breast cancer progression and reduces CD8+ T cell-mediated killing by acetylating USF1 to enhance SLC2A1-mediated glycolysis
Read the full paper: EFO2 promotes triple-negative breast cancer progression and reduces CD8+ T cell-mediated killing by acetylating USF1 to enhance SLC2A1-mediated glycolysis
doi.org
July 17, 2026 at 7:00 AM
@thermofishersci.bsky.social's resource, RRID:AB_10853811, was just reported to be used in the paper. We value the author's support of reproducibility. #methodsmatter #accelerateopenscience #reproducibility
The authors included RRIDs in their None paper! RRIDs improve reproducibility in scientific research. #RRID #RRID #ReproducibleResearch
Knockdown of USF1 and USF2 drives prolonged changes in the gene expression response of M12-5B3 cells to DNA damage
doi.org
July 23, 2025 at 7:02 AM
The authors included RRIDs in their None paper! RRIDs improve reproducibility in scientific research. #RRID #RRID #ReproducibleResearch
Essa pode ser a companheira de Rubinho em 2010 na USF1. <a href="http://migre.me/31G" class="hover:underline text-blue-600 dark:text-sky-400 no-card-link" target="_blank" rel="noopener" data-link="bsky">http://migre.me/31G Pensando bem, até eu voltaria a correr.
November 9, 2024 at 4:58 PM
Essa pode ser a companheira de Rubinho em 2010 na USF1. <a href="http://migre.me/31G" class="hover:underline text-blue-600 dark:text-sky-400 no-card-link" target="_blank" rel="noopener" data-link="bsky">http://migre.me/31G Pensando bem, até eu voltaria a correr.
Peter Windsors first signing for USF1
April 26, 2026 at 6:35 PM
Peter Windsors first signing for USF1
VÍDEO NOVO NO CANAL!
Um jornalista, um engenheiro e um empresário se juntaram para criar uma equipe americana na #F1, a USF1. A empreitada chegou a ter sua vaga confirmada na categoria, a partir de 2010. Mas deu tudo errado... Assista aqui:
www.youtube.com/watch?v=xaw_...
Um jornalista, um engenheiro e um empresário se juntaram para criar uma equipe americana na #F1, a USF1. A empreitada chegou a ter sua vaga confirmada na categoria, a partir de 2010. Mas deu tudo errado... Assista aqui:
www.youtube.com/watch?v=xaw_...
USF1: O PROJETO DE EQUIPE AMERICANA QUE TERMINOU EM VEXAME
YouTube video by Projeto Motor
www.youtube.com
December 9, 2024 at 11:29 PM
VÍDEO NOVO NO CANAL!
Um jornalista, um engenheiro e um empresário se juntaram para criar uma equipe americana na #F1, a USF1. A empreitada chegou a ter sua vaga confirmada na categoria, a partir de 2010. Mas deu tudo errado... Assista aqui:
www.youtube.com/watch?v=xaw_...
Um jornalista, um engenheiro e um empresário se juntaram para criar uma equipe americana na #F1, a USF1. A empreitada chegou a ter sua vaga confirmada na categoria, a partir de 2010. Mas deu tudo errado... Assista aqui:
www.youtube.com/watch?v=xaw_...