Excited (of course) to share our new paper: RNA viruses can exploit self-cleaving ribozymes for translation initiation.
RNA viruses can exploit self-cleaving ribozymes for translation initiation
Abstract. Small self-cleaving ribozymes are catalytic RNAs discovered in viroid-like agents, which are replicating circular RNAs (circRNAs) postulated as r
academic.oup.com
November 2, 2026 at 6:54 PM
Excited (of course) to share our new paper: RNA viruses can exploit self-cleaving ribozymes for translation initiation.
im only reading the wikipedia for this class of virus after you mentioned it so thats my level of specific prior knowledge, but it seems like these dont even meet the current definition of virus because of lacking a viroid?
October 28, 2026 at 6:55 PM
im only reading the wikipedia for this class of virus after you mentioned it so thats my level of specific prior knowledge, but it seems like these dont even meet the current definition of virus because of lacking a viroid?
i like to believe in viroid rna world
October 25, 2026 at 12:18 PM
i like to believe in viroid rna world
March, and it still looks like that
It’s possible your plant has, (Hop Latent Viroid) HlVd
It’s a pathogen that will completely stunt the growth of your plants
It happens sometimes, best to toss out and start over
Especially if you have more than one plant, because it can spread to others
It’s possible your plant has, (Hop Latent Viroid) HlVd
It’s a pathogen that will completely stunt the growth of your plants
It happens sometimes, best to toss out and start over
Especially if you have more than one plant, because it can spread to others
October 18, 2026 at 7:15 AM
March, and it still looks like that
It’s possible your plant has, (Hop Latent Viroid) HlVd
It’s a pathogen that will completely stunt the growth of your plants
It happens sometimes, best to toss out and start over
Especially if you have more than one plant, because it can spread to others
It’s possible your plant has, (Hop Latent Viroid) HlVd
It’s a pathogen that will completely stunt the growth of your plants
It happens sometimes, best to toss out and start over
Especially if you have more than one plant, because it can spread to others
EXTRATERRESTRIAL LIFE, MAYBE
EXTRATERRESTRIAL LIFE, MAYBE Scientists are looking for extraterrestrial life with terrestrial attributes.Extraterrestrials may be different from humans and breathe some other ikpulity*....
EXTRATERRESTRIAL LIFE, MAYBE Scientists are looking for extraterrestrial life with terrestrial attributes.Extraterrestrials may be different from humans and breathe some other ikpulity*....
EXTRATERRESTRIAL LIFE, MAYBE
EXTRATERRESTRIAL LIFE, MAYBE Scientists are looking for extraterrestrial life with terrestrial attributes.Extraterrestrials may be different from humans and breathe some other ikpulity*."Scientists may be looking for the wrong type of extraterrestrial life.There may be other forms of lives that are not humanoid, "plantoid," "animaloid," "bacteroid," "viroid," or other -"oids" seen on earth"—Chidiogo. Ikpulity defined Ikpulity noun\ ikpulity \
africastallestman.com
October 17, 2026 at 1:53 AM
EXTRATERRESTRIAL LIFE, MAYBE
EXTRATERRESTRIAL LIFE, MAYBE Scientists are looking for extraterrestrial life with terrestrial attributes.Extraterrestrials may be different from humans and breathe some other ikpulity*....
EXTRATERRESTRIAL LIFE, MAYBE Scientists are looking for extraterrestrial life with terrestrial attributes.Extraterrestrials may be different from humans and breathe some other ikpulity*....
Viroid: "What are you Library Lesbian hags wearing masks for? The pandemics over!"
AuntiVirus: "Did the worms eating your brain tell you that? Or was it your Immitative-AI brain implant?"
(Work-in-progress text/animation for new Silver Spook game) #indiegame #indiedev
AuntiVirus: "Did the worms eating your brain tell you that? Or was it your Immitative-AI brain implant?"
(Work-in-progress text/animation for new Silver Spook game) #indiegame #indiedev
October 13, 2026 at 5:23 AM
Viroid: "What are you Library Lesbian hags wearing masks for? The pandemics over!"
AuntiVirus: "Did the worms eating your brain tell you that? Or was it your Immitative-AI brain implant?"
(Work-in-progress text/animation for new Silver Spook game) #indiegame #indiedev
AuntiVirus: "Did the worms eating your brain tell you that? Or was it your Immitative-AI brain implant?"
(Work-in-progress text/animation for new Silver Spook game) #indiegame #indiedev
#Honeybees are being trialled as biosensors to detect a disease of #avocado trees in #California. Sunblotch viroid is hard to spot, but through RNA analysis researchers have been able to identify the disease in #pollen bees collect. apsjournals.apsnet.org/doi/abs/10.1...
October 8, 2026 at 9:19 AM
#Honeybees are being trialled as biosensors to detect a disease of #avocado trees in #California. Sunblotch viroid is hard to spot, but through RNA analysis researchers have been able to identify the disease in #pollen bees collect. apsjournals.apsnet.org/doi/abs/10.1...
You are all over the place.
You apparently think the only way a mask protects against an airborne virus is if the filter is so small the actual viroid cannot get through the mesh.
This isn't true. Normal masks prevent water droplets containing the virus from getting spread in the air.
You apparently think the only way a mask protects against an airborne virus is if the filter is so small the actual viroid cannot get through the mesh.
This isn't true. Normal masks prevent water droplets containing the virus from getting spread in the air.
October 7, 2026 at 1:46 AM
You are all over the place.
You apparently think the only way a mask protects against an airborne virus is if the filter is so small the actual viroid cannot get through the mesh.
This isn't true. Normal masks prevent water droplets containing the virus from getting spread in the air.
You apparently think the only way a mask protects against an airborne virus is if the filter is so small the actual viroid cannot get through the mesh.
This isn't true. Normal masks prevent water droplets containing the virus from getting spread in the air.
🧪 The World's Smallest Infectious Entity?
The coconut cadang-cadang viroid (CCCVd) is the smallest known infectious pathogen: a tiny loop of RNA that causes a fatal disease in coconut palms. It isn't a virus; it is just a short piece of RNA, some 246 nucleotides long.
#science #biology #genetics
The coconut cadang-cadang viroid (CCCVd) is the smallest known infectious pathogen: a tiny loop of RNA that causes a fatal disease in coconut palms. It isn't a virus; it is just a short piece of RNA, some 246 nucleotides long.
#science #biology #genetics
September 11, 2026 at 9:10 AM
Few years ago we found that ambiviruses have circular RNA genomes with self-cleaving ribozymes. They replicate like plant viroids but they code for an RdRp.
Here we construct an infectious clone and we go a little further in the understanding of their replication mechanism
doi.org/10.1126/scia...
Here we construct an infectious clone and we go a little further in the understanding of their replication mechanism
doi.org/10.1126/scia...
A newly established reverse genetic system for a circular RNA virus reveals new requirements for infection and its biocontrol potential
Ambiviruses are fungal-infecting circular RNA viruses that uniquely combine viroid-like and viral features, yet the function of their conserved ORF-B protein and their effects on hosts remain unknown,...
www.science.org
September 8, 2026 at 5:22 AM
Few years ago we found that ambiviruses have circular RNA genomes with self-cleaving ribozymes. They replicate like plant viroids but they code for an RdRp.
Here we construct an infectious clone and we go a little further in the understanding of their replication mechanism
doi.org/10.1126/scia...
Here we construct an infectious clone and we go a little further in the understanding of their replication mechanism
doi.org/10.1126/scia...
Viroid-like “obelisk” agents are widespread in the ocean and exceed the abundance of RNA viruses in the prokaryotic fraction
academic.oup.com/ismej/articl...
2025年2月の論文。「オベリスク、実は環境中にわりと普通にいた」らしく面白そう。
academic.oup.com/ismej/articl...
2025年2月の論文。「オベリスク、実は環境中にわりと普通にいた」らしく面白そう。
Viroid-like “obelisk” agents are widespread in the ocean and exceed the abundance of RNA viruses in the prokaryotic fraction
Abstract. “Obelisks” are recently discovered ribonucleic acid (RNA) viroid-like elements present in diverse environments with no phylogenetic similarity to
academic.oup.com
August 24, 2026 at 3:00 AM
Viroid-like “obelisk” agents are widespread in the ocean and exceed the abundance of RNA viruses in the prokaryotic fraction
academic.oup.com/ismej/articl...
2025年2月の論文。「オベリスク、実は環境中にわりと普通にいた」らしく面白そう。
academic.oup.com/ismej/articl...
2025年2月の論文。「オベリスク、実は環境中にわりと普通にいた」らしく面白そう。
I found a paper on BioRxiv available 1/21/2024.
By usual definitions, neither viruses, viroids, nor these Obelisks would be considered alive. But remember that horizontal genetic transfer is important in evolution. We don't know what Obelisks are doing yet. 🧪🧬🧵2/2
www.biorxiv.org/content/10.1...
By usual definitions, neither viruses, viroids, nor these Obelisks would be considered alive. But remember that horizontal genetic transfer is important in evolution. We don't know what Obelisks are doing yet. 🧪🧬🧵2/2
www.biorxiv.org/content/10.1...
Viroid-like colonists of human microbiomes
Here, we describe the “Obelisks,” a previously unrecognised class of viroid-like elements that we first identified in human gut metatranscriptomic data. “Obelisks” share several properties: (i) appare...
www.biorxiv.org
January 3, 2025 at 11:06 PM
I found a paper on BioRxiv available 1/21/2024.
By usual definitions, neither viruses, viroids, nor these Obelisks would be considered alive. But remember that horizontal genetic transfer is important in evolution. We don't know what Obelisks are doing yet. 🧪🧬🧵2/2
www.biorxiv.org/content/10.1...
By usual definitions, neither viruses, viroids, nor these Obelisks would be considered alive. But remember that horizontal genetic transfer is important in evolution. We don't know what Obelisks are doing yet. 🧪🧬🧵2/2
www.biorxiv.org/content/10.1...
A lot of excitement has been going around about a paper in Cell. The paper discussing Obelisks, circular RNA that form rod-like secondary structures, was released Nov. 14, 2024. Similar to plant viroids, they're found in many places, including feces & the mouth.
🧪🧬🧵1/2
www.cell.com/cell/abstrac...
🧪🧬🧵1/2
www.cell.com/cell/abstrac...
Viroid-like colonists of human microbiomes
Obelisks are widespread RNA-based agents found in diverse environmental and human-associated microbiomes. These apparently unbranched and circular RNAs represent a previously uncharacterized class of genetic elements.
www.cell.com
January 3, 2025 at 10:56 PM
A lot of excitement has been going around about a paper in Cell. The paper discussing Obelisks, circular RNA that form rod-like secondary structures, was released Nov. 14, 2024. Similar to plant viroids, they're found in many places, including feces & the mouth.
🧪🧬🧵1/2
www.cell.com/cell/abstrac...
🧪🧬🧵1/2
www.cell.com/cell/abstrac...
The BioRxiv paper (2024.01.20?) said it's now published in Cell. Cell has a decent reputation, but a part of peer review is the fun of ripping apart a paper after it's been published.
There's viroids in plants, and the Obelisks sound similar.
www.cell.com/cell/abstrac...
There's viroids in plants, and the Obelisks sound similar.
www.cell.com/cell/abstrac...
Viroid-like colonists of human microbiomes
Obelisks are widespread RNA-based agents found in diverse environmental and human-associated microbiomes. These apparently unbranched and circular RNAs represent a previously uncharacterized class of genetic elements.
www.cell.com
January 3, 2025 at 10:49 PM
The BioRxiv paper (2024.01.20?) said it's now published in Cell. Cell has a decent reputation, but a part of peer review is the fun of ripping apart a paper after it's been published.
There's viroids in plants, and the Obelisks sound similar.
www.cell.com/cell/abstrac...
There's viroids in plants, and the Obelisks sound similar.
www.cell.com/cell/abstrac...
“Strand Of Life (Viroid)” by Laurie Spiegel #nowplaying #radio3
January 25, 2025 at 9:53 AM
“Strand Of Life (Viroid)” by Laurie Spiegel #nowplaying #radio3
Hey everyone, just letting you know that art commissions are officially open. Please DM me if you want me to draw you something or make you a viroid model here is a example of a viroid model I made and here’s a example of art I made #commisionsopen
May 4, 2025 at 8:51 PM
Hey everyone, just letting you know that art commissions are officially open. Please DM me if you want me to draw you something or make you a viroid model here is a example of a viroid model I made and here’s a example of art I made #commisionsopen
Bier in Gefahr 😱 Schluss mit Lustig.
"Aggressive RNA bedroht Hopfenanbau in Deutschland"
"Ein nur aus RNA bestehender Erreger (Viroid), verbreitet sich rasant unter Hopfenpflanzen. Warum taucht er jetzt in Deutschland auf?"
www.spektrum.de/news/aggress...
"Aggressive RNA bedroht Hopfenanbau in Deutschland"
"Ein nur aus RNA bestehender Erreger (Viroid), verbreitet sich rasant unter Hopfenpflanzen. Warum taucht er jetzt in Deutschland auf?"
www.spektrum.de/news/aggress...
October 18, 2023 at 6:28 PM
Bier in Gefahr 😱 Schluss mit Lustig.
"Aggressive RNA bedroht Hopfenanbau in Deutschland"
"Ein nur aus RNA bestehender Erreger (Viroid), verbreitet sich rasant unter Hopfenpflanzen. Warum taucht er jetzt in Deutschland auf?"
www.spektrum.de/news/aggress...
"Aggressive RNA bedroht Hopfenanbau in Deutschland"
"Ein nur aus RNA bestehender Erreger (Viroid), verbreitet sich rasant unter Hopfenpflanzen. Warum taucht er jetzt in Deutschland auf?"
www.spektrum.de/news/aggress...
#SeminarCBGP | 12/02/21 - 12:30h
👨🏽🔬Dr. Francesco Di Serio
🌍Institute for Sustainable Plant Protection.
National Research Council of Italy. Bari, Italy
📝Viroids and viroid diseases
💻 Zoom ID: 862 6442 3672 | Código acceso: 686797
#somosUPM
👨🏽🔬Dr. Francesco Di Serio
🌍Institute for Sustainable Plant Protection.
National Research Council of Italy. Bari, Italy
📝Viroids and viroid diseases
💻 Zoom ID: 862 6442 3672 | Código acceso: 686797
#somosUPM
November 25, 2024 at 11:57 AM
#SeminarCBGP | 12/02/21 - 12:30h
👨🏽🔬Dr. Francesco Di Serio
🌍Institute for Sustainable Plant Protection.
National Research Council of Italy. Bari, Italy
📝Viroids and viroid diseases
💻 Zoom ID: 862 6442 3672 | Código acceso: 686797
#somosUPM
👨🏽🔬Dr. Francesco Di Serio
🌍Institute for Sustainable Plant Protection.
National Research Council of Italy. Bari, Italy
📝Viroids and viroid diseases
💻 Zoom ID: 862 6442 3672 | Código acceso: 686797
#somosUPM
New on microTalk: How viroids only infect plants, how they stunt growth & potency of cannabis, where they came from, why agricultural practices may enhance spread of the cannabis viroid, & how “beneficial” biological approaches may protect cannabis from infectious agents asm.org/Podcasts/mic...
Weed My Lips: Cannabis Viroids with Dr. Zamir Punja
How viroids only infect plants, how a viroid stunts the growth and potency of cannabis plants, where viroids may have come from, why agricultural practices may enhance the spread of the cannabis viroi...
asm.org
February 11, 2025 at 11:33 PM
New on microTalk: How viroids only infect plants, how they stunt growth & potency of cannabis, where they came from, why agricultural practices may enhance spread of the cannabis viroid, & how “beneficial” biological approaches may protect cannabis from infectious agents asm.org/Podcasts/mic...
On microTalk: How viroids only infect plants, how a viroid stunts the growth and potency of cannabis plants, why agricultural practices may enhance the spread of the cannabis viroid, and how “beneficial” biological approaches may protect cannabis
asm.org/Podcasts/mic...
asm.org/Podcasts/mic...
Weed My Lips: Cannabis Viroids with Dr. Zamir Punja
How viroids only infect plants, how a viroid stunts the growth and potency of cannabis plants, where viroids may have come from, why agricultural practices may enhance the spread of the cannabis viroi...
asm.org
January 27, 2025 at 10:55 PM
On microTalk: How viroids only infect plants, how a viroid stunts the growth and potency of cannabis plants, why agricultural practices may enhance the spread of the cannabis viroid, and how “beneficial” biological approaches may protect cannabis
asm.org/Podcasts/mic...
asm.org/Podcasts/mic...
