Congratulations to Kari Alitalo from #WRIHelsinki on receiving the EVBO @evborg.bsky.social Lifetime Achievement Award in recognition of his outstanding contributions to vascular biology and giving his award lecture at #IVBM2026 in Adelaide!
September 7, 2026 at 11:15 AM
Congratulations to Kari Alitalo from #WRIHelsinki on receiving the EVBO @evborg.bsky.social Lifetime Achievement Award in recognition of his outstanding contributions to vascular biology and giving his award lecture at #IVBM2026 in Adelaide!
Two scientific days in Hanasaari: Wihuri Research Institute Symposium and IMMENs kick-off meeting. Happy to be part of it! Thanks a lot 😊
#WRIHelsinki
www.helsinki.fi/en/researchg...
#WRIHelsinki
www.helsinki.fi/en/researchg...
August 19, 2026 at 9:07 PM
Two scientific days in Hanasaari: Wihuri Research Institute Symposium and IMMENs kick-off meeting. Happy to be part of it! Thanks a lot 😊
#WRIHelsinki
www.helsinki.fi/en/researchg...
#WRIHelsinki
www.helsinki.fi/en/researchg...
New study from Pipsa Saharinen’s lab @pipsasaharinen.bsky.social at #WRIHelsinki, featured on the cover of @jci.org: Integrin conformational switching regulates ANGPT2/TIE2/FOXO1 signaling at endothelial cell junctions.👇
What integrins in the cell junction are doing without classical extracellular matrix ligands: doi.org/10.1172/JCI1...
Sipilä et al. present ANGPT2 in complex with TIE2 and α5β1-integrin via integrative structural biology techniques.
Sipilä et al. present ANGPT2 in complex with TIE2 and α5β1-integrin via integrative structural biology techniques.
June 16, 2026 at 9:13 AM
New study from Pipsa Saharinen’s lab @pipsasaharinen.bsky.social at #WRIHelsinki, featured on the cover of @jci.org: Integrin conformational switching regulates ANGPT2/TIE2/FOXO1 signaling at endothelial cell junctions.👇
New study from Taija Mäkinen's lab @taijamakinenlab.bsky.social at the #WRIHelsinki discovering an essential role for the major angiogenic receptor VEGFR2 in lymphangiogenesis 👇 tinyurl.com/47bns9pp
VEGFR2 is required for VEGF-C–VEGFR3–PI3Kα-mediated sprouting lymphangiogenesis - Nature Communications
How VEGF-C drives functional lymphangiogenesis was unclear. Schoofs et al. show VEGFR2 is required for VEGF-C-VEGFR3-dependent sprouting while VEGFR3 alone drives growth, revealing coordinated receptor signalling in lymphatic network formation.
tinyurl.com
May 29, 2026 at 2:07 PM
New study from Taija Mäkinen's lab @taijamakinenlab.bsky.social at the #WRIHelsinki discovering an essential role for the major angiogenic receptor VEGFR2 in lymphangiogenesis 👇 tinyurl.com/47bns9pp
New study from Kati Öörni’s lab @katioorni.bsky.social at #WRIHelsinki on the effect of icosapent ethyl (IPE) on circulating lipoproteins and their pro-atherogenic properties.👇
Our latest study, published in @insight.jci.org , shows how high-dose icosapent ethyl (IPE), an ethyl ester of eicosapentaenoic acid (EPA) remodels circulating lipoproteins and reduces cardiovascular risk markers in healthy individuals.
insight.jci.org/articles/vie...
insight.jci.org/articles/vie...
October 21, 2025 at 7:30 AM
New study from Kati Öörni’s lab @katioorni.bsky.social at #WRIHelsinki on the effect of icosapent ethyl (IPE) on circulating lipoproteins and their pro-atherogenic properties.👇
New study from Taija Mäkinen's lab @taijamakinenlab.bsky.social at the #WRIHelsinki featured on the cover of @natcardiovascres.nature.com: A ‘feedforward’ circuit amplifying upstream TIE2 receptor signalling drives PIK3CA-driven venous malformation - and can be therapeutically targeted in mice.👇
❤️Our July issue is out❤️Discover an Angiopoietin-TIE2-dependent circuit promoting venous malformations, complex disease modelling in cardiac organoids, regulation of cardiac homeostasis by methyonil tRNA synthetase, and more!
www.nature.com/natcardiovas...
www.nature.com/natcardiovas...
July 17, 2025 at 11:51 AM
New study from Taija Mäkinen's lab @taijamakinenlab.bsky.social at the #WRIHelsinki featured on the cover of @natcardiovascres.nature.com: A ‘feedforward’ circuit amplifying upstream TIE2 receptor signalling drives PIK3CA-driven venous malformation - and can be therapeutically targeted in mice.👇
New study from Riikka Kivelä's lab @riikka-k.bsky.social at the #WRIHelsinki: Combined gene therapy with Pro-MSTN and VEGF-B boosts muscle growth and improves body composition.👇
journals.physiology.org/doi/abs/10.1...
journals.physiology.org/doi/abs/10.1...
Combined angiogenic and hypertrophic gene therapy enhances skeletal muscle growth | American Journal of Physiology-Cell Physiology | American Physiological Society
Skeletal muscle atrophy in response to pathophysiological stimuli or disuse includes loss of muscle mass and strength. Targeting signaling pathways regulating muscle growth can counteract muscle loss,...
journals.physiology.org
July 16, 2025 at 10:16 AM
New study from Riikka Kivelä's lab @riikka-k.bsky.social at the #WRIHelsinki: Combined gene therapy with Pro-MSTN and VEGF-B boosts muscle growth and improves body composition.👇
journals.physiology.org/doi/abs/10.1...
journals.physiology.org/doi/abs/10.1...
New study from Riikka Kivelä’s lab @riikka-k.bsky.social ky.social at the #WRIHelsinki: Mechanical loading triggers cell type-specific responses in endothelial and muscle cells.👇
www.biorxiv.org/content/10.1...
Check how differently muscle cells and endothelial cells respond to mechanical loading from our latest study. Great work by @erikniemi.bsky.social @smantyselka.bsky.social and collaboration with @juhahulmi.bsky.social. Supported by @wrihelsinki.bsky.social
Check how differently muscle cells and endothelial cells respond to mechanical loading from our latest study. Great work by @erikniemi.bsky.social @smantyselka.bsky.social and collaboration with @juhahulmi.bsky.social. Supported by @wrihelsinki.bsky.social
Mechanical loading reveals cell type-specific responses and role of PHGDH in endothelial cell growth
Skeletal muscle and blood vessels are constantly subjected to mechanical forces, especially during exercise. We subjected human endothelial cells (ECs) and muscle cells (MCs) to cyclic mechanical stre...
www.biorxiv.org
July 4, 2025 at 8:22 AM
New study from Riikka Kivelä’s lab @riikka-k.bsky.social ky.social at the #WRIHelsinki: Mechanical loading triggers cell type-specific responses in endothelial and muscle cells.👇