#fluorescencefriday still puzzled how to build such a beautifull periodic pattern #aECM
February 7, 2025 at 10:24 AM
#fluorescencefriday still puzzled how to build such a beautifull periodic pattern #aECM
#aECM at #CellBio2025 On Sunday, the Sundaram lab will have 2 posters on #Celegans aECM - boards 223 and 225
December 6, 2025 at 8:07 PM
#aECM at #CellBio2025 On Sunday, the Sundaram lab will have 2 posters on #Celegans aECM - boards 223 and 225
March 21, 2025 at 11:58 AM
#fluorescenceFriday our favorite giant cell secreting abnormal #aECM
December 6, 2024 at 10:19 AM
#fluorescenceFriday our favorite giant cell secreting abnormal #aECM
another #TEM beauty in #aECM🙏 @nibr3dem.bsky.social
@ibdm.bsky.social and @meera-sundaram.bsky.social
@ibdm.bsky.social and @meera-sundaram.bsky.social
September 23, 2025 at 5:19 PM
another #TEM beauty in #aECM🙏 @nibr3dem.bsky.social
@ibdm.bsky.social and @meera-sundaram.bsky.social
@ibdm.bsky.social and @meera-sundaram.bsky.social
in a new micropub 🙏 @micropub7n.bsky.social we shows the secretion of the Antimicrobial Peptide nlp-29 in the apical extracellular matrix #aECM upon several aECM damage in #Celegans
🙏Henrik Bringmann @cmcb-tud.bsky.social for the KI strain
doi.org/10.17912/mic...
🙏Henrik Bringmann @cmcb-tud.bsky.social for the KI strain
doi.org/10.17912/mic...
April 1, 2025 at 9:07 AM
in a new micropub 🙏 @micropub7n.bsky.social we shows the secretion of the Antimicrobial Peptide nlp-29 in the apical extracellular matrix #aECM upon several aECM damage in #Celegans
🙏Henrik Bringmann @cmcb-tud.bsky.social for the KI strain
doi.org/10.17912/mic...
🙏Henrik Bringmann @cmcb-tud.bsky.social for the KI strain
doi.org/10.17912/mic...
Microvilli control the morphogenesis
of the tectorial membrane extracellular matrix
www.sciencedirect.com/science/arti...
of the tectorial membrane extracellular matrix
www.sciencedirect.com/science/arti...
Microvilli control the morphogenesis of the tectorial membrane extracellular matrix
The apical extracellular matrix (aECM), organized by polarized epithelial cells, exhibits complex structures. The tectorial membrane (TM), an aECM in …
www.sciencedirect.com
December 11, 2024 at 9:54 PM
Microvilli control the morphogenesis
of the tectorial membrane extracellular matrix
www.sciencedirect.com/science/arti...
of the tectorial membrane extracellular matrix
www.sciencedirect.com/science/arti...
Collagen is secreted in soluble form, endocytosed, then resecreted for fibril formation. I’m excited to see this published! It could explain our observations in #Celegans #aECM
Very glad to see this study finally out (and mentioned on bsky already!)- it's been a huge #collaboration across different groups🙏🏻
Fibroblasts recycles (in a #circadian manner) #collagen to make new fibrils, which is enhanced in #fibrosis.
doi.org/10.7554/eLif...
@elife.bsky.social
Fibroblasts recycles (in a #circadian manner) #collagen to make new fibrils, which is enhanced in #fibrosis.
doi.org/10.7554/eLif...
@elife.bsky.social
Endocytic recycling is central to circadian collagen fibrillogenesis and disrupted in fibrosis
Secretion and fibrillogenesis of collagen-I are separately controlled molecular pathways in the fibroblast, where surprisingly endocytic recycling is required for fibril formation and is increased in ...
doi.org
February 5, 2025 at 12:59 PM
The upcoming season of aECM club will cover #aECM glycans, aECM and pathogen interactions, and more. Learn more and sign up here: sundaramlab.com/blog/aecm-cl...
aECM Club Seminars
A virtual seminar series to highlight work on apical ECM across different systems Organizers: Meera Sundaram, UPennMax Heiman, Boston Children’s, Harvard U.Nathalie Pujol, U. Aix MarseilleJor…
sundaramlab.com
August 24, 2026 at 12:49 PM
The upcoming season of aECM club will cover #aECM glycans, aECM and pathogen interactions, and more. Learn more and sign up here: sundaramlab.com/blog/aecm-cl...
youtube.com/watch?v=aecm... shitty video titles like this for clickbait purposes is why I don’t even bother with the Xenoblade fandom anymore 🤚
Are The Xenoblade Genesis Graphics Underwhelming?
YouTube video by SparksOpus
youtube.com
September 26, 2026 at 2:48 AM
youtube.com/watch?v=aecm... shitty video titles like this for clickbait purposes is why I don’t even bother with the Xenoblade fandom anymore 🤚
I made a start at this, but need more #aECM names! Please suggest some! go.bsky.app/QTi9nHY
November 24, 2024 at 11:11 PM
I made a start at this, but need more #aECM names! Please suggest some! go.bsky.app/QTi9nHY
For the last year, aECM Club seminars have brought together researchers working on apical ECM in diverse species and tissues - yeast cell wall, C. elegans cuticle, Drosophila lens, mammalian inner ear and pancreatic lumen, and many others.
Sign up for 2026-27: forms.gle/DDJUxGLkcSRb...
Sign up for 2026-27: forms.gle/DDJUxGLkcSRb...
aECM Club 2026-27
Dear aECM researchers,
Thank you for your interest in aECM Club!
Feel free to forward this brief survey to any colleagues and trainees who may be interested.
forms.gle
August 16, 2026 at 5:52 PM
For the last year, aECM Club seminars have brought together researchers working on apical ECM in diverse species and tissues - yeast cell wall, C. elegans cuticle, Drosophila lens, mammalian inner ear and pancreatic lumen, and many others.
Sign up for 2026-27: forms.gle/DDJUxGLkcSRb...
Sign up for 2026-27: forms.gle/DDJUxGLkcSRb...
🚨pre-print alert🚨
Excited to share the latest work on how cell specific secretion of chitin controls the shape of the fly corneal lens, an #aECM structure.
Excited to share the latest work on how cell specific secretion of chitin controls the shape of the fly corneal lens, an #aECM structure.
Corneal lens curvature depends on localized chitin secretion https://www.biorxiv.org/content/10.1101/2025.08.22.671854v1
August 28, 2025 at 11:45 AM
🚨pre-print alert🚨
Excited to share the latest work on how cell specific secretion of chitin controls the shape of the fly corneal lens, an #aECM structure.
Excited to share the latest work on how cell specific secretion of chitin controls the shape of the fly corneal lens, an #aECM structure.
Spatial memory in tissue architecture: how a transient extracellular scaffold propagates positional information #aECM #Celegans @plos.org 🙏to talented Sophie Mazzoli @ciml.bsky.social @centuri-ls.bsky.social @univ-amu.fr & great collaborations @dynamo-lab.bsky.social @meera-sundaram.bsky.social
🧵👇
🧵👇
May 28, 2026 at 5:32 PM
Spatial memory in tissue architecture: how a transient extracellular scaffold propagates positional information #aECM #Celegans @plos.org 🙏to talented Sophie Mazzoli @ciml.bsky.social @centuri-ls.bsky.social @univ-amu.fr & great collaborations @dynamo-lab.bsky.social @meera-sundaram.bsky.social
🧵👇
🧵👇
#aECM (apical extracellular matrix) is a subset of #ECMatrix that is distinct from stromal matrices or basement membranes. Anybody out there studying #mucins #ZPproteins #cuticle #glycocalyx #surfactant or the like? We need to find each other and start talking!
November 16, 2024 at 2:06 PM
#aECM (apical extracellular matrix) is a subset of #ECMatrix that is distinct from stromal matrices or basement membranes. Anybody out there studying #mucins #ZPproteins #cuticle #glycocalyx #surfactant or the like? We need to find each other and start talking!
Latest from @pujol-lab.bsky.social shows how a transient #aECM factor organizes furrow collagens in the #Celegans cuticle
Pre-cuticle DPY 6 acts as a blueprint for aECM periodic organization in C. elegans https://www.biorxiv.org/content/10.64898/2026.02.21.707041v1
February 24, 2026 at 11:22 PM
Latest from @pujol-lab.bsky.social shows how a transient #aECM factor organizes furrow collagens in the #Celegans cuticle
... a new virtual seminar series on apical extracellular matrix #aECM on different #organisms 🪱🪰🐁🌱🦠will start in Fall 2025, with short talks and discussions
If you are interested
👉https://forms.gle/Y6UjbnXPH1pDHAE97
@meera-sundaram.bsky.social @gotworms.bsky.social @heiman.bsky.social
If you are interested
👉https://forms.gle/Y6UjbnXPH1pDHAE97
@meera-sundaram.bsky.social @gotworms.bsky.social @heiman.bsky.social
July 16, 2025 at 12:25 PM
... a new virtual seminar series on apical extracellular matrix #aECM on different #organisms 🪱🪰🐁🌱🦠will start in Fall 2025, with short talks and discussions
If you are interested
👉https://forms.gle/Y6UjbnXPH1pDHAE97
@meera-sundaram.bsky.social @gotworms.bsky.social @heiman.bsky.social
If you are interested
👉https://forms.gle/Y6UjbnXPH1pDHAE97
@meera-sundaram.bsky.social @gotworms.bsky.social @heiman.bsky.social
#aECM Cub starts next week Nov 18 with talks on patterning the Drosophila lens, mouse tectorial membrane, and C.elegans cuticle furrows. You can still sign up for access using the link below.
The 2025-2026 #aECM club schedule is now posted on our website, where you can also find the link to sign up for access. I’m looking forward to lots of great talks and discussions! sundaramlab.com/blog/aecm-cl...
aECM Club Seminars
A virtual seminar series to highlight work on apical ECM across different systems Organizers: Meera Sundaram, UPennMax Heiman, Boston Children’s, Harvard U.Nathalie Pujol, U. Aix MarseilleJor…
sundaramlab.com
November 14, 2025 at 11:56 AM
#aECM Cub starts next week Nov 18 with talks on patterning the Drosophila lens, mouse tectorial membrane, and C.elegans cuticle furrows. You can still sign up for access using the link below.
The 2025-2026 #aECM club schedule is now posted on our website, where you can also find the link to sign up for access. I’m looking forward to lots of great talks and discussions! sundaramlab.com/blog/aecm-cl...
aECM Club Seminars
A virtual seminar series to highlight work on apical ECM across different systems Organizers: Meera Sundaram, UPennMax Heiman, Boston Children’s, Harvard U.Nathalie Pujol, U. Aix MarseilleJor…
sundaramlab.com
September 23, 2025 at 9:10 AM
The 2025-2026 #aECM club schedule is now posted on our website, where you can also find the link to sign up for access. I’m looking forward to lots of great talks and discussions! sundaramlab.com/blog/aecm-cl...
There is so much cool #aECM work going on but most of the researchers don’t know or talk to each other; this is an attempt to change that! Link below
... a new virtual seminar series on apical extracellular matrix #aECM on different #organisms 🪱🪰🐁🌱🦠will start in Fall 2025, with short talks and discussions
If you are interested
👉https://forms.gle/Y6UjbnXPH1pDHAE97
@meera-sundaram.bsky.social @gotworms.bsky.social @heiman.bsky.social
If you are interested
👉https://forms.gle/Y6UjbnXPH1pDHAE97
@meera-sundaram.bsky.social @gotworms.bsky.social @heiman.bsky.social
July 17, 2025 at 12:14 PM
There is so much cool #aECM work going on but most of the researchers don’t know or talk to each other; this is an attempt to change that! Link below
🆕 & #OpenAccess in Earth Stewardship: Surveys show economic gains, environmental benefits & social synergy drive participation in a farmland climate/conservation program
📄Farmer motivation to participate in cooperative agri-environmental and climate measures
doi.org/10.1002/eas2...
📄Farmer motivation to participate in cooperative agri-environmental and climate measures
doi.org/10.1002/eas2...
April 1, 2025 at 7:35 PM
🆕 & #OpenAccess in Earth Stewardship: Surveys show economic gains, environmental benefits & social synergy drive participation in a farmland climate/conservation program
📄Farmer motivation to participate in cooperative agri-environmental and climate measures
doi.org/10.1002/eas2...
📄Farmer motivation to participate in cooperative agri-environmental and climate measures
doi.org/10.1002/eas2...