How to delay ovary aging?
—Exercise
—And the potential of targeting adiponectin receptor
From 2 large cohorts ~165K participants and extensive studies in mice
nature.com/articles/s43...
—Exercise
—And the potential of targeting adiponectin receptor
From 2 large cohorts ~165K participants and extensive studies in mice
nature.com/articles/s43...
Physical activity delays ovarian aging in part through adiponectin-related signaling pathways - Nature Aging
Physical activity has geroprotective properties, yet its role in ovarian aging is incompletely understood. Here, a cross-sectional analysis of human cohorts links lower physical activity with menopaus...
nature.com
August 14, 2026 at 8:09 PM
How to delay ovary aging?
—Exercise
—And the potential of targeting adiponectin receptor
From 2 large cohorts ~165K participants and extensive studies in mice
nature.com/articles/s43...
—Exercise
—And the potential of targeting adiponectin receptor
From 2 large cohorts ~165K participants and extensive studies in mice
nature.com/articles/s43...
2018 paper in Diabetology & Metabolic Syndrome: "Association of adiponectin with cognitive function precedes overt diabetes in the Brazilian Longitudinal Study of Adult Health: ELSA"
(3 authors overlapping with the sweeteners paper)
My comment: pubpeer.com/publications...
(3 authors overlapping with the sweeteners paper)
My comment: pubpeer.com/publications...
PubPeer - Association of adiponectin with cognitive function precedes...
There are comments on PubPeer for publication: Association of adiponectin with cognitive function precedes overt diabetes in the Brazilian Longitudinal Study of Adult Health: ELSA (2018)
pubpeer.com
November 4, 2025 at 7:06 PM
2018 paper in Diabetology & Metabolic Syndrome: "Association of adiponectin with cognitive function precedes overt diabetes in the Brazilian Longitudinal Study of Adult Health: ELSA"
(3 authors overlapping with the sweeteners paper)
My comment: pubpeer.com/publications...
(3 authors overlapping with the sweeteners paper)
My comment: pubpeer.com/publications...
Adiponectin Role in Breast Cancer Stem Cells and Hormone Therapy Resistance
www.thailandmedical.news/news/adipone...
www.thailandmedical.news/news/adipone...
Adiponectin Role in Breast Cancer Stem Cells and Hormone Therapy Resistance - Thailand Medical News
www.thailandmedical.news
February 16, 2025 at 7:01 AM
Adiponectin Role in Breast Cancer Stem Cells and Hormone Therapy Resistance
www.thailandmedical.news/news/adipone...
www.thailandmedical.news/news/adipone...
New paper on metabolism & AD pathology- first author Eric McG crushes it rdcu.be/d5qox 💕 #GeroSky
Reversal of neuronal tau pathology via adiponectin receptor activation
Communications Biology - Activation of adiponectin receptor signaling in tauopathy-prone primary neurons clears tangles through activation of lysosomes and rescues mitochondrial energetics, lipid...
rdcu.be
January 9, 2025 at 5:13 PM
New paper on metabolism & AD pathology- first author Eric McG crushes it rdcu.be/d5qox 💕 #GeroSky
Recommended 📖 “Adiponectin to the rescue: extracorporeal photopheresis for managing immune checkpoint inhibitor-induced toxicities” @natureportfolio.nature.com co-authored by @drrobinreschke.bsky.social from @nct-heidelberg.bsky.social @dkfz.bsky.social
🔗 www.nature.com/articles/s41...
🔗 www.nature.com/articles/s41...
Adiponectin to the rescue: extracorporeal photopheresis for managing immune checkpoint inhibitor-induced toxicities - Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy - Adiponectin to the rescue: extracorporeal photopheresis for managing immune checkpoint inhibitor-induced toxicities
https://www.nature.com/articles/s41392-025-02205-y\
April 16, 2025 at 7:29 AM
Recommended 📖 “Adiponectin to the rescue: extracorporeal photopheresis for managing immune checkpoint inhibitor-induced toxicities” @natureportfolio.nature.com co-authored by @drrobinreschke.bsky.social from @nct-heidelberg.bsky.social @dkfz.bsky.social
🔗 www.nature.com/articles/s41...
🔗 www.nature.com/articles/s41...
The paper mentioned in the first post is here:
pubpeer.com/publications...
pubpeer.com/publications...
PubPeer - Effect of adiponectin on kidney crystal formation in metabol...
There are comments on PubPeer for publication: Effect of adiponectin on kidney crystal formation in metabolic syndrome model mice via inhibition of inflammation and apoptosis (2013)
pubpeer.com
November 25, 2024 at 1:39 AM
The paper mentioned in the first post is here:
pubpeer.com/publications...
pubpeer.com/publications...
"women are better able to manage glucose...where it can be quickly used when taking part in endurance events...have more adiponectin...and a higher concentration of fatty acids and intramuscular triglycerides...[which] can all enhance glucose use and fat-burning capacities during endurance exercise"
August 20, 2026 at 1:38 PM
"women are better able to manage glucose...where it can be quickly used when taking part in endurance events...have more adiponectin...and a higher concentration of fatty acids and intramuscular triglycerides...[which] can all enhance glucose use and fat-burning capacities during endurance exercise"
🚨New research highlight: study on managing immunotherapy side effects without weakening anti-tumor power!
ECP reduces harmful immune activity via neutrophils/T cells & promotes M2 macrophages via adiponectin.
Promising results from Zeiser et al. 🔬 🧪 🧫
Full summary:
www.nature.com/articles/s41...
ECP reduces harmful immune activity via neutrophils/T cells & promotes M2 macrophages via adiponectin.
Promising results from Zeiser et al. 🔬 🧪 🧫
Full summary:
www.nature.com/articles/s41...
Adiponectin to the rescue: extracorporeal photopheresis for managing immune checkpoint inhibitor-induced toxicities - Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy - Adiponectin to the rescue: extracorporeal photopheresis for managing immune checkpoint inhibitor-induced toxicities
www.nature.com
April 11, 2025 at 9:20 AM
🚨New research highlight: study on managing immunotherapy side effects without weakening anti-tumor power!
ECP reduces harmful immune activity via neutrophils/T cells & promotes M2 macrophages via adiponectin.
Promising results from Zeiser et al. 🔬 🧪 🧫
Full summary:
www.nature.com/articles/s41...
ECP reduces harmful immune activity via neutrophils/T cells & promotes M2 macrophages via adiponectin.
Promising results from Zeiser et al. 🔬 🧪 🧫
Full summary:
www.nature.com/articles/s41...
This is the case that Dr. Bik @elisabethbik.bsky.social informed PLOS ONE in 2015. PLOS ONE retracted the paper in 2024. Nagoya City University has recently denied the image manipulation and criticized the decision of the journal. pubpeer.com/publications...
PubPeer - Effect of adiponectin on kidney crystal formation in metabol...
There are comments on PubPeer for publication: Effect of adiponectin on kidney crystal formation in metabolic syndrome model mice via inhibition of inflammation and apoptosis (2013)
pubpeer.com
November 5, 2025 at 5:01 AM
This is the case that Dr. Bik @elisabethbik.bsky.social informed PLOS ONE in 2015. PLOS ONE retracted the paper in 2024. Nagoya City University has recently denied the image manipulation and criticized the decision of the journal. pubpeer.com/publications...
ccforum.biomedcentral.com/articles/10....
🧪 really interesting review discussing the complex interplay between adiponectin, obesity, and sepsis outcomes and GLP -1.
🧪 really interesting review discussing the complex interplay between adiponectin, obesity, and sepsis outcomes and GLP -1.
Harnessing adiponectin for sepsis: current knowledge, clinical insights and future therapies - Critical Care
Adiponectin, a key adipokine primarily secreted by adipocytes, plays crucial roles in metabolic homeostasis and inflammation, exhibiting anti-diabetic, anti-atherogenic, and anti-inflammatory properti...
ccforum.biomedcentral.com
July 13, 2025 at 12:46 PM
ccforum.biomedcentral.com/articles/10....
🧪 really interesting review discussing the complex interplay between adiponectin, obesity, and sepsis outcomes and GLP -1.
🧪 really interesting review discussing the complex interplay between adiponectin, obesity, and sepsis outcomes and GLP -1.
What is the role of the most abundant #hormone, adiponectin, in metabolic regulation when calories are limited? This study by Yoshiko Ikushima, William Cawthorn &co reveals that adiponectin lowers #glucose and alters nutrient #metabolism under caloric restriction
🧪#AcademicSky
plos.io/4xCNScc
🧪#AcademicSky
plos.io/4xCNScc
June 19, 2026 at 4:09 PM
What is the role of the most abundant #hormone, adiponectin, in metabolic regulation when calories are limited? This study by Yoshiko Ikushima, William Cawthorn &co reveals that adiponectin lowers #glucose and alters nutrient #metabolism under caloric restriction
🧪#AcademicSky
plos.io/4xCNScc
🧪#AcademicSky
plos.io/4xCNScc
Study of 341 patients with early rheumatoid arthritis showed no association between baseline adiponectin, leptin, and resistin levels and the likelihood of achieving CDAI remission over 48 weeks of treatment
In ACR Open Rheumatology
acr.tw/40uulg6
🩺
In ACR Open Rheumatology
acr.tw/40uulg6
🩺
Circulating Adipokines and Response to Treatment in Patients With Early Rheumatoid Arthritis
Objective
The objective of this study was to determine if baseline adiponectin, leptin, and resistin levels are associated with response to antirheumatic treatment in early rheumatoid arthritis (RA).....
acr.tw
November 11, 2024 at 1:41 PM
Study of 341 patients with early rheumatoid arthritis showed no association between baseline adiponectin, leptin, and resistin levels and the likelihood of achieving CDAI remission over 48 weeks of treatment
In ACR Open Rheumatology
acr.tw/40uulg6
🩺
In ACR Open Rheumatology
acr.tw/40uulg6
🩺
my spidey sense is tingling...
![In model 1 of multiple linear regression, adiponectin levels showed to be
associated with delayed recall memory (Table 3), while
prediabetes with learning memory (β −0.080; p=0.015)
and delayed recall memory (β −0.083; p=0.012). After
adjustments (model 2), adiponectin but not prediabetes
maintained independently associated with delayed recall
memory. In the same model, significant associations
of delayed recall memory with the female sex [β 0.243
(95% CI 0.675; 1.212)], age [β −0.110 (95% CI −0.071;
−0.018)], and education level [β 0.205 (95% CI 0.535;
1.063)] were also detected. The inclusion of the interaction variable adiponectin*HOMA-IR did not change the
association between adiponectin levels with improved
delayed recall memory.](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:wk4ks4sjxkducttvaawps2wb/bafkreihkdsjpmg554x5tlv2f7cglgn4ttaguyjtochp7tfpepx4cpzhtyq)
November 4, 2025 at 7:24 PM
my spidey sense is tingling...
What is the role of the most abundant #hormone, adiponectin, in metabolic regulation when calories are limited? This study by Yoshiko Ikushima, William Cawthorn &co reveals that adiponectin lowers #glucose and alters nutrient #metabolism under caloric restriction
🧪#AcademicSky
plos.io/4xCNScc
🧪#AcademicSky
plos.io/4xCNScc
June 19, 2026 at 12:05 PM
What is the role of the most abundant #hormone, adiponectin, in metabolic regulation when calories are limited? This study by Yoshiko Ikushima, William Cawthorn &co reveals that adiponectin lowers #glucose and alters nutrient #metabolism under caloric restriction
🧪#AcademicSky
plos.io/4xCNScc
🧪#AcademicSky
plos.io/4xCNScc
What is the role of the most abundant #hormone, adiponectin, in metabolic regulation when calories are limited? This study by Yoshiko Ikushima, William Cawthorn &co reveals that adiponectin lowers #glucose and alters nutrient #metabolism under caloric restriction
🧪#AcademicSky
plos.io/4xCNScc
🧪#AcademicSky
plos.io/4xCNScc
June 19, 2026 at 8:05 AM
What is the role of the most abundant #hormone, adiponectin, in metabolic regulation when calories are limited? This study by Yoshiko Ikushima, William Cawthorn &co reveals that adiponectin lowers #glucose and alters nutrient #metabolism under caloric restriction
🧪#AcademicSky
plos.io/4xCNScc
🧪#AcademicSky
plos.io/4xCNScc
Results from a recent study suggest a delay in ovarian aging in mice following treadmill training; this effect was mediated by adiponectin. Pharmacologically activating adiponectin receptors extended reproductive span in mice.
👉 Read More: https://ow.ly/L75K50ZQOPr
👉 Read More: https://ow.ly/L75K50ZQOPr
Physical Activity Delays Ovarian Aging in Mice | Lifespan Research Institute
Results from a recent study suggest a delay in ovarian aging in mice following treadmill training; this effect was mediated by adiponectin. Pharmacologically activating adiponectin receptors extended reproductive span in mice. [1] Beyond reproduction The female reproductive system strongly influences the female aging trajectory, and its impact goes well beyond the cessation of reproduction. While
ow.ly
September 24, 2026 at 6:01 PM
Results from a recent study suggest a delay in ovarian aging in mice following treadmill training; this effect was mediated by adiponectin. Pharmacologically activating adiponectin receptors extended reproductive span in mice.
👉 Read More: https://ow.ly/L75K50ZQOPr
👉 Read More: https://ow.ly/L75K50ZQOPr
ok🤯
[lower] adiponectin significantly predicted ketamine’s antidepressant efficacy, suggesting an adverse metabolic state
…adiponectin significantly improves insulin sensitivity & is potently anti-inflammatory[, suggesting] specific systemic abnormalities [to] predict positive response to ketamine
[lower] adiponectin significantly predicted ketamine’s antidepressant efficacy, suggesting an adverse metabolic state
…adiponectin significantly improves insulin sensitivity & is potently anti-inflammatory[, suggesting] specific systemic abnormalities [to] predict positive response to ketamine
The role of adipokines in the rapid antidepressant effects of ketamine - Molecular Psychiatry
Molecular Psychiatry - The role of adipokines in the rapid antidepressant effects of ketamine
www.nature.com
June 19, 2024 at 6:28 PM
ok🤯
[lower] adiponectin significantly predicted ketamine’s antidepressant efficacy, suggesting an adverse metabolic state
…adiponectin significantly improves insulin sensitivity & is potently anti-inflammatory[, suggesting] specific systemic abnormalities [to] predict positive response to ketamine
[lower] adiponectin significantly predicted ketamine’s antidepressant efficacy, suggesting an adverse metabolic state
…adiponectin significantly improves insulin sensitivity & is potently anti-inflammatory[, suggesting] specific systemic abnormalities [to] predict positive response to ketamine
Relationship between maternal #obesity, birth weight, and fetal adiponectin/leptin ratio: a potential early biomarker of cardiometabolic risk @apspublications.bsky.social @dream-diabetes.bsky.social journals.physiology.org/doi/full/10....
Relationship between maternal obesity, birth weight, and fetal adiponectin/leptin ratio: a potential early biomarker of cardiometabolic risk | American Journal of Physiology-Endocrinology and Metaboli...
Adiponectin and leptin are key adipokines that play crucial roles in metabolic regulation and in fetal and neonatal growth. In adults, lower adiponectin/leptin ratio (AdipoQ/Lep) has been suggested as...
journals.physiology.org
December 22, 2025 at 7:17 PM
Relationship between maternal #obesity, birth weight, and fetal adiponectin/leptin ratio: a potential early biomarker of cardiometabolic risk @apspublications.bsky.social @dream-diabetes.bsky.social journals.physiology.org/doi/full/10....
Fresh from our collaborator:
“Elevated circulating adiponectin levels do not prevent anxiety-like behavior in a PCOS-like mouse model”
🔗 www.nature.com/articles/s41...
#neuroskyence
“Elevated circulating adiponectin levels do not prevent anxiety-like behavior in a PCOS-like mouse model”
🔗 www.nature.com/articles/s41...
#neuroskyence
Elevated circulating adiponectin levels do not prevent anxiety-like behavior in a PCOS-like mouse mo...
Scientific Reports - Elevated circulating adiponectin levels do not prevent anxiety-like behavior in a PCOS-like mouse model
www.nature.com
January 8, 2024 at 11:56 AM
Fresh from our collaborator:
“Elevated circulating adiponectin levels do not prevent anxiety-like behavior in a PCOS-like mouse model”
🔗 www.nature.com/articles/s41...
#neuroskyence
“Elevated circulating adiponectin levels do not prevent anxiety-like behavior in a PCOS-like mouse model”
🔗 www.nature.com/articles/s41...
#neuroskyence
Fascinating Promethion-powered science by Fangjun Lin & Tim Gilbertson @UCF - Adiponectin/AdipoR1 signaling modulates fat taste & healthy weight by regulating energy expenditure rather than dietary fat intake in mice! 🧪 www.biorxiv.org/content/10.1...
www.biorxiv.org
March 31, 2025 at 7:07 PM
Fascinating Promethion-powered science by Fangjun Lin & Tim Gilbertson @UCF - Adiponectin/AdipoR1 signaling modulates fat taste & healthy weight by regulating energy expenditure rather than dietary fat intake in mice! 🧪 www.biorxiv.org/content/10.1...
Adiponectin exerts sex-dependent effects on lipid, amino acid, and glucose metabolism during caloric restriction https://www.biorxiv.org/content/10.1101/2025.01.20.633882v1
January 22, 2025 at 11:02 PM
Adiponectin exerts sex-dependent effects on lipid, amino acid, and glucose metabolism during caloric restriction https://www.biorxiv.org/content/10.1101/2025.01.20.633882v1
Even deeper cut? Every biomarker associated with changes in insulin sensitivity improved(adiponectin & IGFBP-2) or dropped(HOMA-IR, FGF21)
Truly seems as if modulating glucagon is like pressing a giant reset button on your metabolism.
Truly seems as if modulating glucagon is like pressing a giant reset button on your metabolism.
June 26, 2026 at 4:47 PM
Even deeper cut? Every biomarker associated with changes in insulin sensitivity improved(adiponectin & IGFBP-2) or dropped(HOMA-IR, FGF21)
Truly seems as if modulating glucagon is like pressing a giant reset button on your metabolism.
Truly seems as if modulating glucagon is like pressing a giant reset button on your metabolism.
Our January cover illustrates detectives hunting down methylation marks to uncover ‘wanted’ loci. In this issue, Sinke et al report that DNA methylation at the SREBF1and ADIPOQ loci is implicated in adiponectin secretion and metabolic disease risk link.springer.com/article/10.1...
January 2, 2026 at 8:53 AM
Our January cover illustrates detectives hunting down methylation marks to uncover ‘wanted’ loci. In this issue, Sinke et al report that DNA methylation at the SREBF1and ADIPOQ loci is implicated in adiponectin secretion and metabolic disease risk link.springer.com/article/10.1...
📃Scientific paper: Brown adipose tissue influences adiponectin and thyroid hormone changes during Graves’ disease thera...
➡️ Continued on ES/IODE
➡️ Continued on ES/IODE
April 4, 2024 at 1:17 AM
📃Scientific paper: Brown adipose tissue influences adiponectin and thyroid hormone changes during Graves’ disease thera...
➡️ Continued on ES/IODE
➡️ Continued on ES/IODE