Calling it syphilitic aortitis is not health-shaming. Think of those poor women and children he raped.
October 15, 2025 at 8:29 PM
Calling it syphilitic aortitis is not health-shaming. Think of those poor women and children he raped.
61-y-o♂️: left upper back pain.
CT angiography: aneurysmal dilatation of aorta (A).
Aneurysm repaired with a graft.
🔬 necrotizing aortitis (B) (neutrophilic & lymphoplasmacytic infiltrates) with spirochetes (C).
½
DOI: 10.1056/NEJMicm2110835
#IDSky #infectious #microbiology
CT angiography: aneurysmal dilatation of aorta (A).
Aneurysm repaired with a graft.
🔬 necrotizing aortitis (B) (neutrophilic & lymphoplasmacytic infiltrates) with spirochetes (C).
½
DOI: 10.1056/NEJMicm2110835
#IDSky #infectious #microbiology
February 18, 2025 at 7:42 AM
61-y-o♂️: left upper back pain.
CT angiography: aneurysmal dilatation of aorta (A).
Aneurysm repaired with a graft.
🔬 necrotizing aortitis (B) (neutrophilic & lymphoplasmacytic infiltrates) with spirochetes (C).
½
DOI: 10.1056/NEJMicm2110835
#IDSky #infectious #microbiology
CT angiography: aneurysmal dilatation of aorta (A).
Aneurysm repaired with a graft.
🔬 necrotizing aortitis (B) (neutrophilic & lymphoplasmacytic infiltrates) with spirochetes (C).
½
DOI: 10.1056/NEJMicm2110835
#IDSky #infectious #microbiology
syphilis + chronic venous insufficiency search results…
July 17, 2025 at 7:09 PM
syphilis + chronic venous insufficiency search results…
Read the latest articles from Clinical Infection Practice including Pneumococcal aortitis: A rare but severe and often undiagnosed vascular complication 👉 www.britishinfection...
April 8, 2026 at 9:00 AM
Read the latest articles from Clinical Infection Practice including Pneumococcal aortitis: A rare but severe and often undiagnosed vascular complication 👉 www.britishinfection...
Past Sexual Promiscuity Increases the Risk of Undetected Syphilitic Aortitis
www.thailandmedical.news/news/past-se...
www.thailandmedical.news/news/past-se...
Past Sexual Promiscuity Increases the Risk of Undetected Syphilitic Aortitis - Thailand Medical News
www.thailandmedical.news
July 14, 2026 at 3:31 AM
Past Sexual Promiscuity Increases the Risk of Undetected Syphilitic Aortitis
www.thailandmedical.news/news/past-se...
www.thailandmedical.news/news/past-se...
Recent lessons, random thoughts
- habit of looking at hands helps catch RA in stoic ppl
- is spondyloarthritis preferred term now?
- NSAIDs make you feel AMAZING = clue
- arthritis can be part of AAV, GCA, other vasculitides
- Ankylosing spondylitis can cause IBD, aortitis etc
- habit of looking at hands helps catch RA in stoic ppl
- is spondyloarthritis preferred term now?
- NSAIDs make you feel AMAZING = clue
- arthritis can be part of AAV, GCA, other vasculitides
- Ankylosing spondylitis can cause IBD, aortitis etc
January 22, 2025 at 3:57 PM
Recent lessons, random thoughts
- habit of looking at hands helps catch RA in stoic ppl
- is spondyloarthritis preferred term now?
- NSAIDs make you feel AMAZING = clue
- arthritis can be part of AAV, GCA, other vasculitides
- Ankylosing spondylitis can cause IBD, aortitis etc
- habit of looking at hands helps catch RA in stoic ppl
- is spondyloarthritis preferred term now?
- NSAIDs make you feel AMAZING = clue
- arthritis can be part of AAV, GCA, other vasculitides
- Ankylosing spondylitis can cause IBD, aortitis etc
Spatially controlled tenascin-C accumulation contributes to inflammatory disease persistence in giant cell aortitis
Spatially controlled tenascin-C accumulation contributes to inflammatory disease persistence in giant cell aortitis - PubMed
Giant cell aortitis (GCA) is an inflammatory disease of the aortic wall with a characteristic giant cell pattern on pathology and can lead to life-threatening aortic aneurysm and dissection. Pathogeni...
pubmed.ncbi.nlm.nih.gov
April 24, 2026 at 11:27 PM
Spatially controlled tenascin-C accumulation contributes to inflammatory disease persistence in giant cell aortitis
Presenting the 1st high-resolution spatial profiling of human aortitis samples:
doi.org/10.1172/jci....
Shi et al. report on TNC accumulation in lesions as contributing to persistent inflammation in giant cell aortitis and find tocilizumab alleviates the phenotype in a cell model.
doi.org/10.1172/jci....
Shi et al. report on TNC accumulation in lesions as contributing to persistent inflammation in giant cell aortitis and find tocilizumab alleviates the phenotype in a cell model.
April 17, 2026 at 11:01 AM
Presenting the 1st high-resolution spatial profiling of human aortitis samples:
doi.org/10.1172/jci....
Shi et al. report on TNC accumulation in lesions as contributing to persistent inflammation in giant cell aortitis and find tocilizumab alleviates the phenotype in a cell model.
doi.org/10.1172/jci....
Shi et al. report on TNC accumulation in lesions as contributing to persistent inflammation in giant cell aortitis and find tocilizumab alleviates the phenotype in a cell model.
Weirdly there is a pretty good argument and decent data indicating a causal relationship between Covid-19 infection and aortitis.
July 13, 2026 at 8:20 AM
Weirdly there is a pretty good argument and decent data indicating a causal relationship between Covid-19 infection and aortitis.
Hypervirulent Klebsiella pneumoniae causing aortitis retains its capsule and mucoviscosity and remains genotypically and phenotypically stable over time.
DOI: 10.1038/s41598-025-23563-1
https://pubmed.ncbi.nlm.nih.gov/41233465/
DOI: 10.1038/s41598-025-23563-1
https://pubmed.ncbi.nlm.nih.gov/41233465/
Hypervirulent Klebsiella pneumoniae causing aortitis retains its capsule and mucoviscosity and remains genotypically and phenotypically stable over time - PubMed
Aortitis due to hypervirulent Klebsiella pneumoniae (hvKp) in a Belarusian male from central New York is described. Isolates at the time of diagnosis (Kp031824-1, Kp031824-2) and after 12 weeks of antimicrobial therapy (Kp070124) were characterized. Kp070124 was genomically and phenotypically unchan …
pubmed.ncbi.nlm.nih.gov
November 22, 2025 at 7:49 AM
Hypervirulent Klebsiella pneumoniae causing aortitis retains its capsule and mucoviscosity and remains genotypically and phenotypically stable over time.
DOI: 10.1038/s41598-025-23563-1
https://pubmed.ncbi.nlm.nih.gov/41233465/
DOI: 10.1038/s41598-025-23563-1
https://pubmed.ncbi.nlm.nih.gov/41233465/
Large-vessel vasculitis is defined as diseases that cause inflammation in large blood vessels.
A new Seminar provides a comprehensive review, with a focus on recent advances, therapeutic approaches, and areas for further research.
Read now: tinyurl.com/ynsfkev5
A new Seminar provides a comprehensive review, with a focus on recent advances, therapeutic approaches, and areas for further research.
Read now: tinyurl.com/ynsfkev5
September 18, 2025 at 2:37 PM
Large-vessel vasculitis is defined as diseases that cause inflammation in large blood vessels.
A new Seminar provides a comprehensive review, with a focus on recent advances, therapeutic approaches, and areas for further research.
Read now: tinyurl.com/ynsfkev5
A new Seminar provides a comprehensive review, with a focus on recent advances, therapeutic approaches, and areas for further research.
Read now: tinyurl.com/ynsfkev5
Pathophysiology of cystic medial necrosis and thoracic aortic aneurysm USMLE
#USMLEStep1 #MedEd #Cardiology #Pathology #ThoracicAneurysm #MarfanSyndrome #Syphilis #Step1Prep #HighYield #MedSchool #InternalMedicine #Aorta #FutureDoctor #StudyGram #MedTwitter #Anki #BoardExams #MedicalStudent #FirstA
#USMLEStep1 #MedEd #Cardiology #Pathology #ThoracicAneurysm #MarfanSyndrome #Syphilis #Step1Prep #HighYield #MedSchool #InternalMedicine #Aorta #FutureDoctor #StudyGram #MedTwitter #Anki #BoardExams #MedicalStudent #FirstA
U01.17.071 Thoracic Aortic Aneurysm (TAA)
U01.17.071 Summary: Explore the weakening of the thoracic aortic wall. Understand the critical distinction between abdominal and thoracic etiologies, focusing on connective tissue disorders, hypertension, and the classic "tree-barking" appearance of the aorta in syphilitic aortitis.
mymedschool.org
April 29, 2026 at 6:29 AM
Pathophysiology of cystic medial necrosis and thoracic aortic aneurysm USMLE
#USMLEStep1 #MedEd #Cardiology #Pathology #ThoracicAneurysm #MarfanSyndrome #Syphilis #Step1Prep #HighYield #MedSchool #InternalMedicine #Aorta #FutureDoctor #StudyGram #MedTwitter #Anki #BoardExams #MedicalStudent #FirstA
#USMLEStep1 #MedEd #Cardiology #Pathology #ThoracicAneurysm #MarfanSyndrome #Syphilis #Step1Prep #HighYield #MedSchool #InternalMedicine #Aorta #FutureDoctor #StudyGram #MedTwitter #Anki #BoardExams #MedicalStudent #FirstA
A 63-year-old man presented with a 3-month history of chest tightness, palpitations, and abdominal pain. Laboratory studies showed an elevated erythrocyte sedimentation rate and an elevated C-reactive protein level. Read the full case details: nej.md/4keccuG
#MedSky #Rheumatology #CardioSky
#MedSky #Rheumatology #CardioSky
February 4, 2026 at 11:00 PM
A 63-year-old man presented with a 3-month history of chest tightness, palpitations, and abdominal pain. Laboratory studies showed an elevated erythrocyte sedimentation rate and an elevated C-reactive protein level. Read the full case details: nej.md/4keccuG
#MedSky #Rheumatology #CardioSky
#MedSky #Rheumatology #CardioSky
New in SJORANM 🫀
Extensive aortitis with Stanford type B intramural hematoma and renal arteritis: a nuclear medicine perspective on infectious vs inflammatory aortitis.
Open access · Peer reviewed · Crossref registered
doi.org/10.59667/sjo...
#Radiology #NuclearMedicine
Extensive aortitis with Stanford type B intramural hematoma and renal arteritis: a nuclear medicine perspective on infectious vs inflammatory aortitis.
Open access · Peer reviewed · Crossref registered
doi.org/10.59667/sjo...
#Radiology #NuclearMedicine
September 25, 2026 at 8:03 AM
New in SJORANM 🫀
Extensive aortitis with Stanford type B intramural hematoma and renal arteritis: a nuclear medicine perspective on infectious vs inflammatory aortitis.
Open access · Peer reviewed · Crossref registered
doi.org/10.59667/sjo...
#Radiology #NuclearMedicine
Extensive aortitis with Stanford type B intramural hematoma and renal arteritis: a nuclear medicine perspective on infectious vs inflammatory aortitis.
Open access · Peer reviewed · Crossref registered
doi.org/10.59667/sjo...
#Radiology #NuclearMedicine
The finding of new aortic regurgitation in a patient with systemic inflammation is a major red flag for pathology of the aortic root, either from endocarditis or aortitis causing annular dilation.
April 16, 2026 at 9:00 PM
The finding of new aortic regurgitation in a patient with systemic inflammation is a major red flag for pathology of the aortic root, either from endocarditis or aortitis causing annular dilation.
💥Today's interdisciplinary case conference featured some rare infectious disease presentations: aortitis caused by C. fetus and otitis due to M. tuberculosis .
Interested in exciting and educational infectious disease case discussions? #idsky #MedSky #IDMedicine #InfectiousDiseases #CaseConference
Interested in exciting and educational infectious disease case discussions? #idsky #MedSky #IDMedicine #InfectiousDiseases #CaseConference
November 4, 2025 at 5:02 PM
💥Today's interdisciplinary case conference featured some rare infectious disease presentations: aortitis caused by C. fetus and otitis due to M. tuberculosis .
Interested in exciting and educational infectious disease case discussions? #idsky #MedSky #IDMedicine #InfectiousDiseases #CaseConference
Interested in exciting and educational infectious disease case discussions? #idsky #MedSky #IDMedicine #InfectiousDiseases #CaseConference
Syphilitic aortitis weakens the aortic wall, potentially leading to an aortic aneurysm, a bulge that risks rupture. 🤞
Damage to the aortic valve is also common, resulting in aortic regurgitation, where the valve fails to close properly, stressing the heart & causing heart failure.
3/
Damage to the aortic valve is also common, resulting in aortic regurgitation, where the valve fails to close properly, stressing the heart & causing heart failure.
3/
February 7, 2026 at 8:50 AM
Syphilitic aortitis weakens the aortic wall, potentially leading to an aortic aneurysm, a bulge that risks rupture. 🤞
Damage to the aortic valve is also common, resulting in aortic regurgitation, where the valve fails to close properly, stressing the heart & causing heart failure.
3/
Damage to the aortic valve is also common, resulting in aortic regurgitation, where the valve fails to close properly, stressing the heart & causing heart failure.
3/
Interesingly, the histology revealed a familial small cell aortitis from my mother's side. They're doing the genetic studies now. I didn't know it but I have six 1st cousins with aortic aneurysms (out of 41 first cousins total). The whole family will be screened now, which is a good thing.
October 19, 2025 at 12:20 AM
Interesingly, the histology revealed a familial small cell aortitis from my mother's side. They're doing the genetic studies now. I didn't know it but I have six 1st cousins with aortic aneurysms (out of 41 first cousins total). The whole family will be screened now, which is a good thing.
My husband had a severe type3 hypersensitivity reaction to Pfizer resulting in initial meningitis and vasculitis/aortitis resolving into autoimmunity/neurological disease and a thoracic aortic aneurysm also developed v severe ME which has improved to mildish he can now move around with a frame
November 21, 2024 at 9:38 AM
My husband had a severe type3 hypersensitivity reaction to Pfizer resulting in initial meningitis and vasculitis/aortitis resolving into autoimmunity/neurological disease and a thoracic aortic aneurysm also developed v severe ME which has improved to mildish he can now move around with a frame
attending on id - day 5
bacterial infection of native aorta - 2 cases in the past few months.
here are the most common pathogens (swedish study):
www.annalsofvascularsurgery.com/article/S089...
and here's a classic on salmonella from a mentor, dr. salit:
academic.oup.com/cid/article-...
#idsky
bacterial infection of native aorta - 2 cases in the past few months.
here are the most common pathogens (swedish study):
www.annalsofvascularsurgery.com/article/S089...
and here's a classic on salmonella from a mentor, dr. salit:
academic.oup.com/cid/article-...
#idsky
Salmonella Aortitis
A successfully treated case of Salmonella infection of the thoracic aorta is described. Salmonella enteritidis was isolated from blood cultures and from operative cultures of the aorta. Computed tomog...
jamanetwork.com
March 18, 2025 at 10:33 PM
attending on id - day 5
bacterial infection of native aorta - 2 cases in the past few months.
here are the most common pathogens (swedish study):
www.annalsofvascularsurgery.com/article/S089...
and here's a classic on salmonella from a mentor, dr. salit:
academic.oup.com/cid/article-...
#idsky
bacterial infection of native aorta - 2 cases in the past few months.
here are the most common pathogens (swedish study):
www.annalsofvascularsurgery.com/article/S089...
and here's a classic on salmonella from a mentor, dr. salit:
academic.oup.com/cid/article-...
#idsky
Clinical Images: Sarcoidosis with concomitant aortitis and coronary arteritis
In ACR Open Rheumatology
loom.ly/NjichsY
A 49y/o Black female patient with HIV diagnosed and on therapy for 19 yrs and a 12-yr history of pulmonary sarcoidosis was evaluated for chest pain radiating to the left arm. 🩺
In ACR Open Rheumatology
loom.ly/NjichsY
A 49y/o Black female patient with HIV diagnosed and on therapy for 19 yrs and a 12-yr history of pulmonary sarcoidosis was evaluated for chest pain radiating to the left arm. 🩺
![A 49-year-old Black female patient with HIV diagnosed and on therapy for 19 years and a 12-year history of pulmonary sarcoidosis was evaluated for chest pain radiating to the left arm. She was on prednisone 10 mg daily for several years but stopped two years before her presentation. Erythrocyte sedimentation rate and troponin T were elevated: 41 mm/hour (reference: <20 mm/hour) and 52 ng/L (reference <10 ng/L), respectively. HIV RNA was undetectable, CD4 T-cells 887/mcL, antinuclear antibodies, antineutrophil cytoplasmic antibodies, and serum IgG4 were within reference ranges.
Coronary computed tomography angiography (panels A–B: Diffuse, circumferential soft-tissue thickening of the wall of the left anterior descending coronary artery [red arrow: axial plane; blue arrow: cross sectional image]; panels C–D: Diffuse wall thickening of the mid right coronary artery [purple arrow] and in cross-section [brown arrow] through the proximal right coronary artery; [continued...]](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:g5fr5vggcyl7dq3ub7zmdwrz/bafkreick6mafbnlnh7c6w4vjiwb3m75oevpl276b7r5ppybxbdfy34hude)
January 26, 2024 at 10:24 PM
Clinical Images: Sarcoidosis with concomitant aortitis and coronary arteritis
In ACR Open Rheumatology
loom.ly/NjichsY
A 49y/o Black female patient with HIV diagnosed and on therapy for 19 yrs and a 12-yr history of pulmonary sarcoidosis was evaluated for chest pain radiating to the left arm. 🩺
In ACR Open Rheumatology
loom.ly/NjichsY
A 49y/o Black female patient with HIV diagnosed and on therapy for 19 yrs and a 12-yr history of pulmonary sarcoidosis was evaluated for chest pain radiating to the left arm. 🩺