A Hitchhiker’s Guide to Precision Medicine in Glomerulonephritis #AskRenal #CanadaSky
@csnscn.bsky.social @sagepub.com
doi.org/10.1177/2054...
@csnscn.bsky.social @sagepub.com
doi.org/10.1177/2054...
October 27, 2026 at 12:08 PM
A Hitchhiker’s Guide to Precision Medicine in Glomerulonephritis #AskRenal #CanadaSky
@csnscn.bsky.social @sagepub.com
doi.org/10.1177/2054...
@csnscn.bsky.social @sagepub.com
doi.org/10.1177/2054...
The consequences of deletion of the adenosine A2b receptor from fibroblasts in mice with obstructive uropathy caused by unilateral ureteral obstruction. #AskRenal #Nephrology
@csnscn.bsky.social @unityhealthto.bsky.social
doi.org/10.1177/2054...
@csnscn.bsky.social @unityhealthto.bsky.social
doi.org/10.1177/2054...
October 26, 2026 at 2:02 PM
The consequences of deletion of the adenosine A2b receptor from fibroblasts in mice with obstructive uropathy caused by unilateral ureteral obstruction. #AskRenal #Nephrology
@csnscn.bsky.social @unityhealthto.bsky.social
doi.org/10.1177/2054...
@csnscn.bsky.social @unityhealthto.bsky.social
doi.org/10.1177/2054...
You order net zero UF for CRRT.
One assessment in the morning.
ICU team orders a NS bolus to help with the BP.
Nurse pulls it out the next hour.
#AskRenal what do you do to avoid this? I’m trying to figure out a practical solution.
One assessment in the morning.
ICU team orders a NS bolus to help with the BP.
Nurse pulls it out the next hour.
#AskRenal what do you do to avoid this? I’m trying to figure out a practical solution.
October 13, 2026 at 3:09 PM
You order net zero UF for CRRT.
One assessment in the morning.
ICU team orders a NS bolus to help with the BP.
Nurse pulls it out the next hour.
#AskRenal what do you do to avoid this? I’m trying to figure out a practical solution.
One assessment in the morning.
ICU team orders a NS bolus to help with the BP.
Nurse pulls it out the next hour.
#AskRenal what do you do to avoid this? I’m trying to figure out a practical solution.
Excellent work modelling effect of ER visit in patients with out-patient hyperkalemia
K>6.2 carries 1.6% risk of death in next 7 days
Decreased by ER visit within 1, 3, 7 days, & the sooner the better
Effects greatest for K>6.6 and GFR<30
#nephsky #askrenal #medsky
www.cmaj.ca/content/198/...
K>6.2 carries 1.6% risk of death in next 7 days
Decreased by ER visit within 1, 3, 7 days, & the sooner the better
Effects greatest for K>6.6 and GFR<30
#nephsky #askrenal #medsky
www.cmaj.ca/content/198/...
Emergency department referral and short-term death after outpatient hyperkalemia: a population-based study
Background:Hyperkalemia can be deadly, yet clinical decision-making for outpatient management is unclear. We sought to determine whether an emergency department encounter within 24 hours of a severe o...
www.cmaj.ca
September 13, 2026 at 5:22 PM
Excellent work modelling effect of ER visit in patients with out-patient hyperkalemia
K>6.2 carries 1.6% risk of death in next 7 days
Decreased by ER visit within 1, 3, 7 days, & the sooner the better
Effects greatest for K>6.6 and GFR<30
#nephsky #askrenal #medsky
www.cmaj.ca/content/198/...
K>6.2 carries 1.6% risk of death in next 7 days
Decreased by ER visit within 1, 3, 7 days, & the sooner the better
Effects greatest for K>6.6 and GFR<30
#nephsky #askrenal #medsky
www.cmaj.ca/content/198/...
What do #livingkidneydonors feel is the most difficult part of donating a kidney? Find out this and more in the link below 👇 #CanadianResearch #organdonation #AskRenal
doi.org/10.1177/2054...
doi.org/10.1177/2054...
August 10, 2026 at 1:20 PM
What do #livingkidneydonors feel is the most difficult part of donating a kidney? Find out this and more in the link below 👇 #CanadianResearch #organdonation #AskRenal
doi.org/10.1177/2054...
doi.org/10.1177/2054...
Decent (albeit almost all observational) data suggest that response to terlipressin is crap in HRS-AKI in patients presenting with SCr >5 mg/dL. Does that apply to norepi as well???
@juancarlosqvelez.bsky.social
@captainchloride.bsky.social
#nephsky #askrenal
@juancarlosqvelez.bsky.social
@captainchloride.bsky.social
#nephsky #askrenal
November 21, 2024 at 6:35 AM
Decent (albeit almost all observational) data suggest that response to terlipressin is crap in HRS-AKI in patients presenting with SCr >5 mg/dL. Does that apply to norepi as well???
@juancarlosqvelez.bsky.social
@captainchloride.bsky.social
#nephsky #askrenal
@juancarlosqvelez.bsky.social
@captainchloride.bsky.social
#nephsky #askrenal
What’s your treatment for idiopathic pericarditis in PD?
NSAIDs will cause loss of RRF and risk of UGIB. Colchicine at even low doses=diarrhea (and myopathy/cytopenias). Prednisone or try colchicine 0.3-0.6mg po daily to see if tolerated? Defer to cardiology? @askrenal.bsky.social #askrenal
NSAIDs will cause loss of RRF and risk of UGIB. Colchicine at even low doses=diarrhea (and myopathy/cytopenias). Prednisone or try colchicine 0.3-0.6mg po daily to see if tolerated? Defer to cardiology? @askrenal.bsky.social #askrenal
July 8, 2025 at 3:46 AM
What’s your treatment for idiopathic pericarditis in PD?
NSAIDs will cause loss of RRF and risk of UGIB. Colchicine at even low doses=diarrhea (and myopathy/cytopenias). Prednisone or try colchicine 0.3-0.6mg po daily to see if tolerated? Defer to cardiology? @askrenal.bsky.social #askrenal
NSAIDs will cause loss of RRF and risk of UGIB. Colchicine at even low doses=diarrhea (and myopathy/cytopenias). Prednisone or try colchicine 0.3-0.6mg po daily to see if tolerated? Defer to cardiology? @askrenal.bsky.social #askrenal
February 11, 2025 at 5:18 PM
July 19, 2025 at 4:40 PM
Since atrasentan is bound to be approved for use in IgAN, does anyone know whether it will be revived for DKD?
SONAR did in fact show that it was effective, but the premature termination and upstaging by CREDENCE sort of left atrasentan for dead…
#askrenal
SONAR did in fact show that it was effective, but the premature termination and upstaging by CREDENCE sort of left atrasentan for dead…
#askrenal
April 5, 2026 at 6:14 AM
Since atrasentan is bound to be approved for use in IgAN, does anyone know whether it will be revived for DKD?
SONAR did in fact show that it was effective, but the premature termination and upstaging by CREDENCE sort of left atrasentan for dead…
#askrenal
SONAR did in fact show that it was effective, but the premature termination and upstaging by CREDENCE sort of left atrasentan for dead…
#askrenal
#askrenal Just been told that enalapril 10 mg is max dose for HTN, but label says up to 40 mg per day.
Anyone know the RCT data on enalapril in HTN?
@hswapnil.medsky.social @jordybc.bsky.social @drjmluther.bsky.social
Anyone know the RCT data on enalapril in HTN?
@hswapnil.medsky.social @jordybc.bsky.social @drjmluther.bsky.social
February 26, 2025 at 9:28 AM
#askrenal Just been told that enalapril 10 mg is max dose for HTN, but label says up to 40 mg per day.
Anyone know the RCT data on enalapril in HTN?
@hswapnil.medsky.social @jordybc.bsky.social @drjmluther.bsky.social
Anyone know the RCT data on enalapril in HTN?
@hswapnil.medsky.social @jordybc.bsky.social @drjmluther.bsky.social
#askrenal Does anyone else get the suspicion that significant hypoK with thiazides is a demasking of hyperaldosteronism? Is there any data to support this? @jordybc.bsky.social @hswapnil.bsky.social @drjmluther.bsky.social
January 15, 2025 at 4:36 PM
#askrenal Does anyone else get the suspicion that significant hypoK with thiazides is a demasking of hyperaldosteronism? Is there any data to support this? @jordybc.bsky.social @hswapnil.bsky.social @drjmluther.bsky.social
Anyone have any thoughts on this great question posed by my colleague @AdeelRafiAhmed: Why is dexamethasone not first line for severe GN/ vasculitis when clearly it has better anti inflammatory activity and no mineral corticoid activity? #askrenal
November 22, 2024 at 8:02 PM
Anyone have any thoughts on this great question posed by my colleague @AdeelRafiAhmed: Why is dexamethasone not first line for severe GN/ vasculitis when clearly it has better anti inflammatory activity and no mineral corticoid activity? #askrenal
What have been challenges to developing information apps for patients with kidney disease? What do patients want from these apps? What are good information sources for patients? Any feedback much appreciated. #AskRenal
November 22, 2024 at 1:54 PM
What have been challenges to developing information apps for patients with kidney disease? What do patients want from these apps? What are good information sources for patients? Any feedback much appreciated. #AskRenal
Check out this incredible blog by @drnikhil.bsky.social & kajareeG discussing whether a 3K dialysis bath with an oral potassium-lowering agent on HD days reduces arrhythmias! 🩺💙 Join us for the #NephJC chat at 9 PM EST today on Bluesky 🕘✨ #medsky #nephsky #askrenal
Is adding SZC + 3K bath the solution to sudden death in dialysis?
Join us this on #NephJC to discuss
www.nephjc.com/news/potassi...
#NephSky
Join us this on #NephJC to discuss
www.nephjc.com/news/potassi...
#NephSky
Potassium Rollercoaster Heartbreak — NephJC
This week, we will discuss the use of 3K dialysis bath with sodium zirconium cyclosilicate versus 2K bath and no potassium lowering medications in dialysis patients and the associated risk of arrhythm...
www.nephjc.com
November 19, 2024 at 12:48 PM
Check out this incredible blog by @drnikhil.bsky.social & kajareeG discussing whether a 3K dialysis bath with an oral potassium-lowering agent on HD days reduces arrhythmias! 🩺💙 Join us for the #NephJC chat at 9 PM EST today on Bluesky 🕘✨ #medsky #nephsky #askrenal
Brief question regarding acute shunt occlusion: What potassium levels are acceptable to your anesthesia team for surgery (shunt thrombectomy) without requiring Shaldon catheter placement and prior dialysis? Are there any guidelines or official recommendations we could reference?
#askrenal #nephsky
#askrenal #nephsky
January 7, 2025 at 7:33 PM
How often have you seen Ferric Carboxymaltose cause hypophosphatemia? @kidneyboy.bsky.social @hswapnil.medsky.social @askrenal.bsky.social #askrenal
pubmed.ncbi.nlm.nih.gov/39659775/
pubmed.ncbi.nlm.nih.gov/39659775/
In-depth clinical characterization of intravenous iron infusion-induced hypophosphatemic osteomalacia and its resolution - PubMed
Iron deficiency anemia is treated by iron supplementation. Increasing evidence has shown that the carbohydrate components in iron infusions can cause hypophosphatemia and subsequent osteomalacia due t...
pubmed.ncbi.nlm.nih.gov
April 21, 2025 at 9:23 PM
How often have you seen Ferric Carboxymaltose cause hypophosphatemia? @kidneyboy.bsky.social @hswapnil.medsky.social @askrenal.bsky.social #askrenal
pubmed.ncbi.nlm.nih.gov/39659775/
pubmed.ncbi.nlm.nih.gov/39659775/
#AskRenal
I have a 72 year old on Automated PD since 2022 who initially defaulted PD for months and once recommenced on PD developed vomiting while on PD. Non compliant to follow-up and his last PET test in early 2023 showed a HA transporter.
I have a 72 year old on Automated PD since 2022 who initially defaulted PD for months and once recommenced on PD developed vomiting while on PD. Non compliant to follow-up and his last PET test in early 2023 showed a HA transporter.
July 13, 2026 at 10:44 AM
#AskRenal
I have a 72 year old on Automated PD since 2022 who initially defaulted PD for months and once recommenced on PD developed vomiting while on PD. Non compliant to follow-up and his last PET test in early 2023 showed a HA transporter.
I have a 72 year old on Automated PD since 2022 who initially defaulted PD for months and once recommenced on PD developed vomiting while on PD. Non compliant to follow-up and his last PET test in early 2023 showed a HA transporter.
Quick question - if I want to give Cefoperazone-Sulbactam for IP antibiotics for Automated PD with 10L exchanges can I use the Cefoperazone data in ISPD guidelines ie 500mg/L loading with 125mg/L for maintainence or is that overkill? #AskRenal
April 21, 2026 at 2:27 AM
Quick question - if I want to give Cefoperazone-Sulbactam for IP antibiotics for Automated PD with 10L exchanges can I use the Cefoperazone data in ISPD guidelines ie 500mg/L loading with 125mg/L for maintainence or is that overkill? #AskRenal
#NephTwittershtag/NephTwitter" class="hover:underline text-blue-600 dark:text-sky-400 no-card-link">#NephTwitter can offer answers from international experts to what you are wondering. @askrenal #NephTwitter #NUKidontheSwap 14/n
November 22, 2024 at 11:15 PM
#NephTwittershtag/NephTwitter" class="hover:underline text-blue-600 dark:text-sky-400 no-card-link">#NephTwitter can offer answers from international experts to what you are wondering. @askrenal #NephTwitter #NUKidontheSwap 14/n