January 18, 2025 at 7:15 PM
"The neonatal Fc receptor is a cellular receptor for human astrovirus"
www.nature.com/articles/s41...
www.nature.com/articles/s41...
The neonatal Fc receptor is a cellular receptor for human astrovirus - Nature Microbiology
A CRISPR-based screen identifies neonatal Fc receptor (FcRn) and dipeptidyl-peptidase IV (DPP4) as entry factors for human astrovirus, and targeting them using available therapies effectively prevents...
www.nature.com
December 12, 2024 at 6:44 AM
"The neonatal Fc receptor is a cellular receptor for human astrovirus"
www.nature.com/articles/s41...
www.nature.com/articles/s41...
March 22, 2025 at 10:06 PM
December 15, 2024 at 5:13 PM
New enemy almost ready to export over to #Unity3D for Astrovirus.
#GameDev | #IndieGameDev | #Blender
#GameDev | #IndieGameDev | #Blender
March 3, 2025 at 2:18 PM
New enemy almost ready to export over to #Unity3D for Astrovirus.
#GameDev | #IndieGameDev | #Blender
#GameDev | #IndieGameDev | #Blender
Happy #ScreenshotSaturday 👽✌️
Polishing and bug fixes continue for Astrovirus.
#GameDev | #MadeWithUnity | #IndieGame
Polishing and bug fixes continue for Astrovirus.
#GameDev | #MadeWithUnity | #IndieGame
December 14, 2024 at 11:59 PM
Happy #ScreenshotSaturday 👽✌️
Polishing and bug fixes continue for Astrovirus.
#GameDev | #MadeWithUnity | #IndieGame
Polishing and bug fixes continue for Astrovirus.
#GameDev | #MadeWithUnity | #IndieGame
April 17, 2025 at 2:50 PM
Great addition to the Astrovirus story, with numerous novel strain and viruses in pigeons, rats, bats and shrews on Reunion Island. The identification of Avastrovirus 2 (i.e. bird associated astrovirus species) in bats worth follow up.
👉 journals.asm.org/doi/full/10....
👉 journals.asm.org/doi/full/10....
January 27, 2025 at 9:40 PM
Great addition to the Astrovirus story, with numerous novel strain and viruses in pigeons, rats, bats and shrews on Reunion Island. The identification of Avastrovirus 2 (i.e. bird associated astrovirus species) in bats worth follow up.
👉 journals.asm.org/doi/full/10....
👉 journals.asm.org/doi/full/10....
January 25, 2025 at 10:33 PM
From initial design to rigged, animated, and textured. It's time to make this thing fly and shoot around in Astrovirus.
#GameDev | #IndieGame | #Blender
#GameDev | #IndieGame | #Blender
March 4, 2025 at 4:05 PM
From initial design to rigged, animated, and textured. It's time to make this thing fly and shoot around in Astrovirus.
#GameDev | #IndieGame | #Blender
#GameDev | #IndieGame | #Blender
Mucosal stargazing: IgA keeps astrovirus in check @cp-cellhostmicrobe.bsky.social
www.cell.com/cell-host-mi...
www.cell.com/cell-host-mi...
www.cell.com/cell-host-mi...
www.cell.com/cell-host-mi...
April 10, 2025 at 4:04 PM
Mucosal stargazing: IgA keeps astrovirus in check @cp-cellhostmicrobe.bsky.social
www.cell.com/cell-host-mi...
www.cell.com/cell-host-mi...
www.cell.com/cell-host-mi...
www.cell.com/cell-host-mi...
Big congratulations to the authors! 🎉🦠 Using RNA-seq, this study uncovers overlooked viral RNA species and supports a premature termination model for astrovirus subgenomic RNA synthesis, resolving a long-standing replication mystery. 🔬✨
#NARMolecularMedicine #Virology
@universitypress.cambridge.org
#NARMolecularMedicine #Virology
@universitypress.cambridge.org
🚨 New paper from the lab! 🚀 We explore “The dynamics and strategy of RNA replication in astroviruses”, now out in NAR Molecular Medicine. Many thanks to all co-authors and congratulations to David Noyvert on his first first-author paper🎉
doi.org/10.1093/narm...
doi.org/10.1093/narm...
The dynamics and strategy of RNA replication in astroviruses
Abstract. Astroviruses are positive-sense single-stranded RNA viruses that cause significant disease across avian and mammalian hosts, yet their replicatio
doi.org
May 20, 2026 at 3:17 PM
Big congratulations to the authors! 🎉🦠 Using RNA-seq, this study uncovers overlooked viral RNA species and supports a premature termination model for astrovirus subgenomic RNA synthesis, resolving a long-standing replication mystery. 🔬✨
#NARMolecularMedicine #Virology
@universitypress.cambridge.org
#NARMolecularMedicine #Virology
@universitypress.cambridge.org
Astrovirus gameplay is more cohesive, but still noticing too much input lag. I've been replacing all my instantiate & destroy calls with object pooling, smoother gameplay incoming!
#GameDev | #IndieDev | #IndieGame
#GameDev | #IndieDev | #IndieGame
April 24, 2025 at 1:42 PM
Astrovirus gameplay is more cohesive, but still noticing too much input lag. I've been replacing all my instantiate & destroy calls with object pooling, smoother gameplay incoming!
#GameDev | #IndieDev | #IndieGame
#GameDev | #IndieDev | #IndieGame
New screenshots from the mobile game I'm working on, Astrovirus.
#ScreenshotSaturday | #IndieGameDev | #MadeWithUnity
#ScreenshotSaturday | #IndieGameDev | #MadeWithUnity
February 22, 2025 at 10:16 PM
New screenshots from the mobile game I'm working on, Astrovirus.
#ScreenshotSaturday | #IndieGameDev | #MadeWithUnity
#ScreenshotSaturday | #IndieGameDev | #MadeWithUnity
Happy #ScreenshotSaturday
Taking a bit of a break for the holidays. Looking forward to jumping back into development for Astrovirus and setting a release date 👽✌️🚀
#IndieGameDev | #GameDev
Taking a bit of a break for the holidays. Looking forward to jumping back into development for Astrovirus and setting a release date 👽✌️🚀
#IndieGameDev | #GameDev
December 22, 2024 at 4:36 AM
Happy #ScreenshotSaturday
Taking a bit of a break for the holidays. Looking forward to jumping back into development for Astrovirus and setting a release date 👽✌️🚀
#IndieGameDev | #GameDev
Taking a bit of a break for the holidays. Looking forward to jumping back into development for Astrovirus and setting a release date 👽✌️🚀
#IndieGameDev | #GameDev
📢Astrovirus polyprotein processing is finally uncovered - these viruses use peculiar dual cleavage sites around their protease! Led by a talented PhD student, David Noyvert, this work provides a map of astrovirus genomes. Great collaboration with @emmottlab.bsky.social @leandroxneves.bsky.social
Viral protease-mediated polyprotein processing in human astroviruses
Positive-sense RNA viruses often encode large polyproteins that are proteolytically processed by viral and host proteases into functional replication proteins. Astroviruses infect intestinal and neuro...
www.biorxiv.org
November 25, 2025 at 10:08 PM
📢Astrovirus polyprotein processing is finally uncovered - these viruses use peculiar dual cleavage sites around their protease! Led by a talented PhD student, David Noyvert, this work provides a map of astrovirus genomes. Great collaboration with @emmottlab.bsky.social @leandroxneves.bsky.social
January 10, 2025 at 10:45 PM
Hey, Bluesky.
I'm excited to share what I've been working on. Here's a quick how it started vs how it's going for my game, Astrovirus.
#IndieGameDev | #GameDev | #SoloDev
I'm excited to share what I've been working on. Here's a quick how it started vs how it's going for my game, Astrovirus.
#IndieGameDev | #GameDev | #SoloDev
November 20, 2024 at 3:34 AM
Hey, Bluesky.
I'm excited to share what I've been working on. Here's a quick how it started vs how it's going for my game, Astrovirus.
#IndieGameDev | #GameDev | #SoloDev
I'm excited to share what I've been working on. Here's a quick how it started vs how it's going for my game, Astrovirus.
#IndieGameDev | #GameDev | #SoloDev
New enemy type has made it into my latest test build of Astrovirus, along with a new auto-turret weapon that I most definitely will be tweaking the audio on 😅
#IndieGames | #GameDev | #IndieGameDev
#IndieGames | #GameDev | #IndieGameDev
March 25, 2025 at 3:24 AM
New enemy type has made it into my latest test build of Astrovirus, along with a new auto-turret weapon that I most definitely will be tweaking the audio on 😅
#IndieGames | #GameDev | #IndieGameDev
#IndieGames | #GameDev | #IndieGameDev
Endoplasmic reticulum-anchored nonstructural proteins drive human astrovirus replication organelle formation
journals.plos.org/plospathogen...
journals.plos.org/plospathogen...
Endoplasmic reticulum-anchored nonstructural proteins drive human astrovirus replication organelle formation
Author summary Human astroviruses (HAstV) are understudied, globally prevalent pathogens capable of causing potentially fatal infections of the central nervous system in children, the elderly, and imm...
journals.plos.org
September 22, 2025 at 10:33 PM
Endoplasmic reticulum-anchored nonstructural proteins drive human astrovirus replication organelle formation
journals.plos.org/plospathogen...
journals.plos.org/plospathogen...
Continued bug hunting for Astrovirus! Gameplay mechanics are working nicely together, time to go back through for some polishing.
#IndieGameDev | #GameDev | #FollowFriday
#IndieGameDev | #GameDev | #FollowFriday
January 17, 2025 at 5:24 PM
Continued bug hunting for Astrovirus! Gameplay mechanics are working nicely together, time to go back through for some polishing.
#IndieGameDev | #GameDev | #FollowFriday
#IndieGameDev | #GameDev | #FollowFriday
Eggs, groceries, and cars aren’t the only things going up—𝐝𝐢𝐬𝐞𝐚𝐬𝐞 𝐫𝐚𝐭𝐞𝐬 𝐚𝐫𝐞 𝐭𝐨𝐨
Meanwhile, Elon ‘saved’ enough with cost-cutting to give himself $𝟒𝟎𝟎𝐌 𝐟𝐨𝐫 𝐂𝐲𝐛𝐞𝐫 𝐭𝐫𝐮𝐜𝐤𝐬
We must 𝐰𝐢𝐧 𝐚𝐥𝐥 𝟑 𝐬𝐩𝐞𝐜𝐢𝐚𝐥 𝐞𝐥𝐞𝐜𝐭𝐢𝐨𝐧𝐬 𝐭𝐨 𝐟𝐥𝐢𝐩 𝐭𝐡𝐞 𝐇𝐨𝐮𝐬𝐞 & take back Congress in 2026 & presidency in 2028—before it’s too late.
🧵 ⬇️
Meanwhile, Elon ‘saved’ enough with cost-cutting to give himself $𝟒𝟎𝟎𝐌 𝐟𝐨𝐫 𝐂𝐲𝐛𝐞𝐫 𝐭𝐫𝐮𝐜𝐤𝐬
We must 𝐰𝐢𝐧 𝐚𝐥𝐥 𝟑 𝐬𝐩𝐞𝐜𝐢𝐚𝐥 𝐞𝐥𝐞𝐜𝐭𝐢𝐨𝐧𝐬 𝐭𝐨 𝐟𝐥𝐢𝐩 𝐭𝐡𝐞 𝐇𝐨𝐮𝐬𝐞 & take back Congress in 2026 & presidency in 2028—before it’s too late.
🧵 ⬇️
February 14, 2025 at 2:55 AM
Eggs, groceries, and cars aren’t the only things going up—𝐝𝐢𝐬𝐞𝐚𝐬𝐞 𝐫𝐚𝐭𝐞𝐬 𝐚𝐫𝐞 𝐭𝐨𝐨
Meanwhile, Elon ‘saved’ enough with cost-cutting to give himself $𝟒𝟎𝟎𝐌 𝐟𝐨𝐫 𝐂𝐲𝐛𝐞𝐫 𝐭𝐫𝐮𝐜𝐤𝐬
We must 𝐰𝐢𝐧 𝐚𝐥𝐥 𝟑 𝐬𝐩𝐞𝐜𝐢𝐚𝐥 𝐞𝐥𝐞𝐜𝐭𝐢𝐨𝐧𝐬 𝐭𝐨 𝐟𝐥𝐢𝐩 𝐭𝐡𝐞 𝐇𝐨𝐮𝐬𝐞 & take back Congress in 2026 & presidency in 2028—before it’s too late.
🧵 ⬇️
Meanwhile, Elon ‘saved’ enough with cost-cutting to give himself $𝟒𝟎𝟎𝐌 𝐟𝐨𝐫 𝐂𝐲𝐛𝐞𝐫 𝐭𝐫𝐮𝐜𝐤𝐬
We must 𝐰𝐢𝐧 𝐚𝐥𝐥 𝟑 𝐬𝐩𝐞𝐜𝐢𝐚𝐥 𝐞𝐥𝐞𝐜𝐭𝐢𝐨𝐧𝐬 𝐭𝐨 𝐟𝐥𝐢𝐩 𝐭𝐡𝐞 𝐇𝐨𝐮𝐬𝐞 & take back Congress in 2026 & presidency in 2028—before it’s too late.
🧵 ⬇️
Happy #TrailerTuesday 💚
I'm excited to share with other #IndieDevs my first gameplay trailer for my first #IndieGame, a space shoot 'em up mobile game: Astrovirus.
youtu.be/zLRtuJHazYg?...
I'm excited to share with other #IndieDevs my first gameplay trailer for my first #IndieGame, a space shoot 'em up mobile game: Astrovirus.
youtu.be/zLRtuJHazYg?...
Astrovirus Gameplay Trailer
YouTube video by OFJOY
youtu.be
December 3, 2024 at 4:09 PM
Happy #TrailerTuesday 💚
I'm excited to share with other #IndieDevs my first gameplay trailer for my first #IndieGame, a space shoot 'em up mobile game: Astrovirus.
youtu.be/zLRtuJHazYg?...
I'm excited to share with other #IndieDevs my first gameplay trailer for my first #IndieGame, a space shoot 'em up mobile game: Astrovirus.
youtu.be/zLRtuJHazYg?...
Start screen for Astrovirus. Just added some new animations and a smoother transition when you hit play, based on feedback I've received. Video coming soon 👽
#MadeWithUnity | #GameDev | #IndieGame
#MadeWithUnity | #GameDev | #IndieGame
November 22, 2024 at 11:03 PM
Start screen for Astrovirus. Just added some new animations and a smoother transition when you hit play, based on feedback I've received. Video coming soon 👽
#MadeWithUnity | #GameDev | #IndieGame
#MadeWithUnity | #GameDev | #IndieGame
February 25, 2025 at 3:53 AM