YouTube video by Alexander von Humboldt-Stiftung

The new genus Garciamycella is here erected to accommodate the soil-borne fungus G. chlamydospora, as well as G. cyclaminis and G. fici, based on a phylogenetic study using sequences of ITS, LSU, rpb2...

A decahydrofluorene-class alkaloid, pyrrospirone Z (1a), along with pyrrospirone F (2), pyrrospirone M (3), GKK1032A2 (4), daldinol (5), orthosporin (6), and 3,4-dihydro-3,4,8-trihydroxy-1(2H)-naphtha...

This study describes the isolation and characterization of potent bioactive compounds from the fungal strain Neonothopanus nambi, followed by structural elucidation. The compounds shown are dimeric a....

In the course of biochemical prospection of Laburnicola nematophila isolated from eggs of the plant-parasitic cyst nematode Heterodera filipjevi, eight 2-pyridone alkaloids were isolated from its solid-state BRFT cultures and identified as six previously undescribed, cordypyridones E–J (1–6), and two known congeners, cordypyridones C (7) and D (8). The structures and absolute configurations of all isolated compounds were elucidated through HR-ESI–MS, 1D/2D NMR spectroscopy, and TDDFT–ECD calculations. Compound 4, bearing a rare N-hydroxy-2-pyridone moiety structurally related to that of PF1140, exhibited broad-spectrum bioactivity in cytotoxicity and antimicrobial assays. Compounds 5 and 6 demonstrated potent antibiofilm activities against Staphylococcus aureus, reducing its biofilm formation by almost 50% at 0.25 and 7.8 μg/mL, respectively.

Erstmals trafen sich 60 Gastgebende zu einem Scout-Netzwerktreffen in Bonn.