Nucleic acid-ligand conjugates combine the distinct properties of macromolecular ligands with the versatility of DNA/RNA nanotechnology. In biomaterial and nanomedicine applications, highly purified ...

Cytokines are potent endogenous modulators of innate immunity, making them key mediators of macrophage plasticity for immunotherapy. However, the clin…

This chemistry wordoku takes it lead from an expert in bioconjugates in human health!

Abstract. Protein bioconjugates are at the forefront of precision medicine, enabling the design of highly selective drugs for diagnostic and therapeutic ap

A novel class of flavonoid-pectin bioconjugates sourced via cavitation of citrus processing waste, citrus IntegroPectin pectic polymers exhibit a complex structural synergy between the pectic backbone...

Read the full paper: Scalable Purification of Cowpea Chlorotic Mottle Virus (CCMV) and Its Bioconjugates From Plant Extracts Using Ultrafiltration

Eli Lilly will invest $5B in a new Virginia plant to boost U.S. production of cancer drugs and bioconjugates, creating 650 jobs and expanding its domestic manufacturing footprint.

Cytokines are potent endogenous modulators of innate immunity, making them key mediators of macrophage plasticity for immunotherapy. However, the clin…

WuXi XDC and BioDlink successfully hosted the 2026 Open Day, unveiling a new era for bioconjugate therapies through collaboration.

We report a novel approach to study allostery which combines the use of carefully selected bioconjugates and hydrogen–deuterium exchange mass spectrometry (HDX-MS). This strategy avoids issues related...

The synthesis of novel carbohydrate–oligonucleotide conjugates is described. These bioconjugates, which feature glycosyl-nucleoside moieties linked to a thymine base via a 1,2,3-triazole linker, were…

Gaseous reagents are an emerging class of bioconjugation reagents that can offer alternative selectivity paradigms for the construction of precise bioconjugates. A variety of both inert and highly re...

Functional enzyme–gold nanoparticle bioconjugates are becoming increasingly important in bioelectrocatalysis since they facilitate and improve the efficiency of long-range protein interfacial electron...

The site-selective modification of protein N-termini represents a powerful strategy for producing homogeneous bioconjugates. 2-Pyridinecarboxaldehydes have emerged as a leading reagent class in this area. However, these conjugations suffer from relatively slow rates and a degree of reversibility. In this work, we therefore studied the effects of pyridinecarboxaldehyde functionalization on N-terminal modification. This allowed us to provide insight into the factors governing relative contributions from competing reaction pathways and design criteria for second generation reagents for protein labeling. Importantly, 3-methoxy-2-pyridinecarboxaldehydes were identified as providing both accelerated and more stable protein labeling, enabling further applications of this powerful technology.

Posted 8:20:30 PM. The Company:AI Proteins is a Boston-based biotechnology company focused on the de novo design and…See this and similar jobs on LinkedIn.

Xcellon Biologics, a Maryland CRDMO specializing in bioconjugates and complex biologics, has signed a definitive agreement to acquire the GMP biologics…

Read the full paper: Modular Assembly of Bioconjugates Enabled by a Pyridine-Based Chemoselective Sequential Conjugation Platform

Read the full paper: Modular Assembly of Bioconjugates Enabled by a Pyridine-Based Chemoselective Sequential Conjugation Platform

Therapeutic proteins are commonly conjugated with polymers to modulate their pharmacokinetics but often lack a description of the polymer-protein interaction. We deployed limited proteolysis mass spe...

PhD Project - Developing a bioanalytical platform for evaluating oligonucleotide-antibody bioconjugates at University of Strathclyde, listed on FindAPhD.com