L-carnitine?
September 21, 2026 at 9:18 AM
L-carnitine?
It's time to rewrite reviews-aKG doesn't just regulate demethylation. Work from my lab and @mzspectrum.bsky.social demonstrates a new role for aKG in promoting histone acetylation and DNA repair through regulating carnitine synthesis. Congrats Apoorva Uboveja! www.nature.com/articles/s41...
αKG-mediated carnitine synthesis drives DNA repair via histone acetylation - Nature
The metabolite αKG promotes carnitine synthesis and increases site-specific histone acetylation, thereby promoting homologous recombination-mediated DNA repair, which has potential implications f...
www.nature.com
May 27, 2026 at 3:42 PM
It's time to rewrite reviews-aKG doesn't just regulate demethylation. Work from my lab and @mzspectrum.bsky.social demonstrates a new role for aKG in promoting histone acetylation and DNA repair through regulating carnitine synthesis. Congrats Apoorva Uboveja! www.nature.com/articles/s41...
Our paper on the human carnitine transporter OCTN2 (SLC22A5) is out in @natcomms.nature.com! We solved structures of OCTN2 in multiple states and explored how carnitine transport is Na⁺-dependent, providing a framework for understanding SPCD disease causing variants and drug interactions.
Structural basis of sodium ion-dependent carnitine transport by OCTN2
Nature Communications - Carnitine uptake by OCTN2 supports fatty acid metabolism. Here, authors report cryo-EM structures of human OCTN2, revealing the mechanism of sodium ion-dependent carnitine...
rdcu.be
January 8, 2026 at 12:05 AM
Our paper on the human carnitine transporter OCTN2 (SLC22A5) is out in @natcomms.nature.com! We solved structures of OCTN2 in multiple states and explored how carnitine transport is Na⁺-dependent, providing a framework for understanding SPCD disease causing variants and drug interactions.
A mitochondrial transport protein promotes carnitine synthesis in mice when fat consumption is needed.
Learn more in a new #SciencePerspective: https://scim.ag/40fV7Hw
Learn more in a new #SciencePerspective: https://scim.ag/40fV7Hw
The bottleneck of fat burning
A mitochondrial transport protein promotes carnitine synthesis in mice when fat consumption is needed
scim.ag
February 22, 2026 at 6:20 PM
A mitochondrial transport protein promotes carnitine synthesis in mice when fat consumption is needed.
Learn more in a new #SciencePerspective: https://scim.ag/40fV7Hw
Learn more in a new #SciencePerspective: https://scim.ag/40fV7Hw
Refill on whey, creatine, and some carnitine
September 28, 2026 at 9:25 PM
Refill on whey, creatine, and some carnitine
Note: For cats, one has to supplement plant food with carnitine and taurine but there are vegan options for this.
September 29, 2026 at 6:29 PM
Note: For cats, one has to supplement plant food with carnitine and taurine but there are vegan options for this.
recently learned, 1) L-carnitine increases libido 2) L-carnitine is in monster
might explain some things 🤔
might explain some things 🤔
June 25, 2025 at 7:18 AM
recently learned, 1) L-carnitine increases libido 2) L-carnitine is in monster
might explain some things 🤔
might explain some things 🤔
Nothing makes Carnitine Beastmoder want to go on grindr like a margherita
August 29, 2026 at 9:09 PM
Nothing makes Carnitine Beastmoder want to go on grindr like a margherita
Coach has got me adding injectable L- Carnitine into the mix for my cut
Should be interesting ✨
Should be interesting ✨
June 4, 2025 at 8:52 AM
Coach has got me adding injectable L- Carnitine into the mix for my cut
Should be interesting ✨
Should be interesting ✨
supplement haul of a girl who lives a fun and interesting life
September 12, 2026 at 12:00 AM
supplement haul of a girl who lives a fun and interesting life
Nature research paper: αKG-mediated carnitine synthesis drives DNA repair via histone acetylation
go.nature.com/3POPIFZ
go.nature.com/3POPIFZ
αKG-mediated carnitine synthesis drives DNA repair via histone acetylation - Nature
The metabolite αKG promotes carnitine synthesis and increases site-specific histone acetylation, thereby promoting homologous recombination-mediated DNA repair, which has potential implications for chemoresistant cancers.
go.nature.com
June 1, 2026 at 9:17 AM
Nature research paper: αKG-mediated carnitine synthesis drives DNA repair via histone acetylation
go.nature.com/3POPIFZ
go.nature.com/3POPIFZ
Following reading this trial, I tried this supplement & noticed some improvement. Twice I stopped taking it & noticed a deterioration. Many who have tried L-carnitine probably didn't take a sufficient dosage +/or they tried acetyl l-carnitine
plioplys.com/wp-content/u...
#MEcfs #CFS #PwME
plioplys.com/wp-content/u...
#MEcfs #CFS #PwME
August 17, 2024 at 10:12 AM
Following reading this trial, I tried this supplement & noticed some improvement. Twice I stopped taking it & noticed a deterioration. Many who have tried L-carnitine probably didn't take a sufficient dosage +/or they tried acetyl l-carnitine
plioplys.com/wp-content/u...
#MEcfs #CFS #PwME
plioplys.com/wp-content/u...
#MEcfs #CFS #PwME
Energy drink cans are amazing literature.
ACESULFAME, L-CARNITINE, SUCRALOSE, INOSITOL,
natural strawberry flavoring
ACESULFAME, L-CARNITINE, SUCRALOSE, INOSITOL,
natural strawberry flavoring
May 22, 2025 at 8:13 AM
Energy drink cans are amazing literature.
ACESULFAME, L-CARNITINE, SUCRALOSE, INOSITOL,
natural strawberry flavoring
ACESULFAME, L-CARNITINE, SUCRALOSE, INOSITOL,
natural strawberry flavoring
Excited to share our work on discovery of SLC25A45 as a mediator of mitochondrial methylated amino acid import and carnitine biosynthesis. @cp-cellmetabolism.bsky.social www.cell.com/cell-metabol...
Machine-learning-guided discovery of SLC25A45 as a mediator of mitochondrial methylated amino acid import and carnitine synthesis
Khan et al. apply machine learning to identify substrates of UNC93A, SLC45A4, and
SLC25A45. Biochemical assays and in vivo metabolite tracing establish SLC25A45 as
a key mediator of mitochondrial impo...
www.cell.com
October 11, 2025 at 4:15 PM
Excited to share our work on discovery of SLC25A45 as a mediator of mitochondrial methylated amino acid import and carnitine biosynthesis. @cp-cellmetabolism.bsky.social www.cell.com/cell-metabol...
#NatMetabPicks | In @science.org led by S Kajimura et al. ( @hsph.harvard.edu @hhmi-science.bsky.social )
Mitochondrial SLC25A45-mediated carnitine biosynthesis is required for cold adaptation and GLP-1RA efficacy.
🧪
www.science.org/doi/10.1126/...
Mitochondrial SLC25A45-mediated carnitine biosynthesis is required for cold adaptation and GLP-1RA efficacy.
🧪
www.science.org/doi/10.1126/...
Mitochondrial control of fuel switching via carnitine biosynthesis
Environmental adaptation often involves a shift in energy utilization toward mitochondrial fatty acid oxidation, which requires carnitine. Besides dietary sources of animal origin, carnitine biosynthe...
www.science.org
January 12, 2026 at 5:33 PM
#NatMetabPicks | In @science.org led by S Kajimura et al. ( @hsph.harvard.edu @hhmi-science.bsky.social )
Mitochondrial SLC25A45-mediated carnitine biosynthesis is required for cold adaptation and GLP-1RA efficacy.
🧪
www.science.org/doi/10.1126/...
Mitochondrial SLC25A45-mediated carnitine biosynthesis is required for cold adaptation and GLP-1RA efficacy.
🧪
www.science.org/doi/10.1126/...
A healthy individual's body can synthesise L-carnitine (via your liver and kidneys) by using lysine and methionine.
September 21, 2026 at 9:25 AM
A healthy individual's body can synthesise L-carnitine (via your liver and kidneys) by using lysine and methionine.
My dumb brain always sees "carnitas"
August 3, 2025 at 1:43 PM
My dumb brain always sees "carnitas"
ordered l-carnitine
watch this space
watch this space
April 17, 2026 at 3:40 AM
ordered l-carnitine
watch this space
watch this space
Need a carnitine post about curly brunette woman
August 25, 2026 at 8:48 AM
Need a carnitine post about curly brunette woman
new out in Nature www.nature.com/articles/s41...
αKG-mediated carnitine synthesis drives DNA repair via histone acetylation - Nature
The metabolite αKG promotes carnitine synthesis and increases site-specific histone acetylation, thereby promoting homologous recombination-mediated DNA repair, which has potential implications f...
www.nature.com
May 28, 2026 at 6:47 AM
new out in Nature www.nature.com/articles/s41...
The loneliness of a long distance swimmer - had double scoops of Creatine and Carnitine this morning - hit the ocean pool and put in a bit over four kilometres - time for a walk and a late lunch 😻
November 23, 2025 at 2:53 AM
The loneliness of a long distance swimmer - had double scoops of Creatine and Carnitine this morning - hit the ocean pool and put in a bit over four kilometres - time for a walk and a late lunch 😻
L-Carnitine is the second L in LL Cool J
October 26, 2025 at 3:12 PM
L-Carnitine is the second L in LL Cool J
Last 2 weeks of research papers relevant to #MitochondrialDisease!
biomed.news/bims-mitdis/...
biomed.news/bims-mitdis/...
@biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social
Mitochondrial control of fuel switching via carnitine biosynthesis
www.science.org/doi/10.1126/...
biomed.news/bims-mitdis/...
biomed.news/bims-mitdis/...
@biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social
Mitochondrial control of fuel switching via carnitine biosynthesis
www.science.org/doi/10.1126/...
Mitochondrial control of fuel switching via carnitine biosynthesis
Environmental adaptation often involves a shift in energy utilization toward mitochondrial fatty acid oxidation, which requires carnitine. Besides dietary sources of animal origin, carnitine biosynthe...
www.science.org
January 11, 2026 at 12:53 PM
Last 2 weeks of research papers relevant to #MitochondrialDisease!
biomed.news/bims-mitdis/...
biomed.news/bims-mitdis/...
@biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social
Mitochondrial control of fuel switching via carnitine biosynthesis
www.science.org/doi/10.1126/...
biomed.news/bims-mitdis/...
biomed.news/bims-mitdis/...
@biomednews.bsky.social @gavinmcstay.bsky.social @mitoscientist.bsky.social
Mitochondrial control of fuel switching via carnitine biosynthesis
www.science.org/doi/10.1126/...
[drinking my energy drink with taurine, l-carnitine, and b-vitamins]
Thank god there’s no sugar
Thank god there’s no sugar
February 12, 2026 at 4:28 PM
[drinking my energy drink with taurine, l-carnitine, and b-vitamins]
Thank god there’s no sugar
Thank god there’s no sugar
