#ccvi24
Now: Michael Hoffman: Human papillomavirus integration transforms chromatin to drive oncogenesis #ccvi24 🧪🧬🔄🖥️
September 6, 2024 at 4:58 PM
Excited to be live-posting the next two days at the Chromatin Control of Viral Infection workshop at NIH. 🧪🧬🔄🖥️ #EpiSci #ccvi24
September 5, 2024 at 1:25 PM
Now: Davide Maestri: EBNA-LP cooperates with YY1 and CTCF architectural proteins in reshaping B cell genome #ccvi24 🧪🧬🔄🖥️
September 6, 2024 at 4:46 PM
Now: Craig Wilen: Epigenetic regulation of coronavirus susceptibility #ccvi24 🧪🧬🔄🖥️
September 5, 2024 at 3:52 PM
Now: Edward Browne: CRISPR/chemical screening, histone methyltransferase SETD2, HIV expression, and latency #ccvi24 🧪🧬🔄🖥️
September 5, 2024 at 3:04 PM
Now: Cheng-Ming Chiang: Phospho-BRD4 IDR-targeting compounds as antiviral and anticancer agents #ccvi24 🧪🧬🔄🖥️
September 5, 2024 at 3:31 PM
Now: Melania Bruno: Sequence reconstruction of KRAB-zinc finger gene clusters reveals modes of their rapid evolution in mice #ccvi24 🧪🧬🔄🖥️
September 5, 2024 at 1:48 PM
Now: Harald Wodrich: Mechanistic insight into adenovirus chromatin anchoring #ccvi24 🧪🧬🔄🖥️
September 5, 2024 at 6:53 PM
Reminder: making conclusions by eyeballing a UMAP is unsound and unscientific. #ccvi24 🧪🧬🔄🖥️
September 6, 2024 at 3:20 PM
Now: Ya-Chi Ho: HIV-host chromatin interactions at the HIV integration site #ccvi24 🧪🧬🔄🖥️
September 6, 2024 at 2:54 PM
DM: Yin-yang-1 (YYI) named because can be coactivator or corepressor, works with CTCF to organize genome architecture #ccvi24
September 6, 2024 at 4:47 PM
Now: Paul Lesbats: Timely chromatin invasion during mitosis governs Prototype Foamy virus integration site selection and infectivity #ccvi24 🧪🧬🔄🖥️
September 6, 2024 at 3:42 PM
Now: Selene Ingusci: Comparison of viral and cellular insulators in promoting durable HSV-1 vector mediated transgene expression in muscle and brain. #ccvi24 🧪🧬🔄🖥️
September 6, 2024 at 5:44 PM
HW: TP binds H2A/H2B dimer but not H3/H4 #ccvi24
September 5, 2024 at 6:59 PM
MB: KRAB-zinc finger proteins are a special family of TFs that bind to DNA and chromatin remodelers. Large family of genes that exploded in mammals and rapidly evolving. #ccvi24
September 5, 2024 at 1:50 PM
FR: AST promotes HIV-1 latency in the Jurkat E4 model. #ccvi24
September 6, 2024 at 3:40 PM
HW: Adenoviral genomes associate with mitotic chromosomes. Viral genome anchors to cellular chromatin #ccvi24
September 5, 2024 at 6:56 PM
CL: p400 complex regulates RNAPII pause release in cellular genes and even moreso in HIV genes. #ccvi24
September 5, 2024 at 2:55 PM
CW: CRISPR screen identified SWI/SNF chromatin as essential for SARS-CoV-2. cBAF regulates chromatin accessibility at ACE2 locus. HNF1A binds and targets cBAF to ACE2 locus. cBAF inhibitors block ACE2 expression and viral entry #ccvi24
September 5, 2024 at 3:59 PM
Now: Italo Tempera: Cell metabolism and epigenetic regulation in Epstein-Barr Virus latent infection #ccvi24 🧪🧬🔄🖥️
September 5, 2024 at 1:29 PM
Now: Ben Gewurz: Chromatin control of the Epstein-Barr Virus B-cell lytic switch #ccvi24 🧪🧬🔄🖥️
September 6, 2024 at 5:16 PM
Now: Leah Kottyan: Human cytomegalovirus infection coopts chromatin organization to diminish TEAD1 transcription factor activity #ccvi24 🧪🧬🔄🖥️
September 6, 2024 at 4:31 PM
DM: EBV infection determines rearrangement in genome architecture. 1/Primary infection of B cell. 2/Reorganization of genome architecture. #ccvi24
September 6, 2024 at 4:47 PM
Y-CH: HIV-1 hides in cytotoxic CD4+ T cells, the best fighters #ccvi24 https://www.cell.com/immunity/fulltext/S1074-7613(22)00127-3
September 6, 2024 at 3:08 PM