In a study, researchers detect neonicotinoid and diamide insecticide contamination in nearly all of the 200 soil samples collected from urban residential areas across ten provinces in China between Oc...

In a study, researchers detect neonicotinoid and diamide insecticide contamination in nearly all of the 200 soil samples collected from urban residential areas across ten provinces in China between Oc...

In a study, researchers detect neonicotinoid and diamide insecticide contamination in nearly all of the 200 soil samples collected from urban residential areas across ten provinces in China between Oc...

In a study, researchers detect neonicotinoid and diamide insecticide contamination in nearly all of the 200 soil samples collected from urban residential areas across ten provinces in China between October and December 2024.

While diamide insecticides (DAIs) are new alternatives to conventional pesticides with improved selectivity, their environmental footprint needs an investigation. To that end, a nationwide study published in Environmental Chemistry and Ecotoxicology created a pollution snapshot to elucidate the widespread occurrence of DAIs in rivers across nine major Chinese basins, "We found four DAIs across rivers in 47 Chinese cities," shares corresponding author Yanhao Zhang. "The compounds were found at concentrations from below detection limit to 119 ng/L, with a national median total concentration of 40 ng/L." Cyantraniliprole (CYTP) was the predominant contaminant, with a median concentration of 17 ng/L and a 100% detection frequency. "The chemical composition patterns varied by regions," says Zhang. "CYTP contributed most in southern basins, while broflanilide (BFA) made a larger contribution in northern basins." Local crop-planting patterns and crop-specific pesticide-use potentially shaped the regional pollution signatures. Land-use and meteorological variables did could not explain the differences of nationwide distribution. Notably, there was a mismatch between concentration and ecological risk. "BFA was not the most abundant pollutant, yet it became the main screening-level driver for the benthic midge Chironomus dilutus because its species-specific chronic effect threshold was much lower," shares Zhang. "BFA screening RQs exceeded 1...

While diamide insecticides (DAIs) are new alternatives to conventional pesticides with improved selectivity, their environmental footprint needs an investigation. To that end, a nationwide study published in Environmental Chemistry and Ecotoxicology created a pollution snapshot to elucidate the widespread occurrence of DAIs in rivers across nine major Chinese basins, "We found four DAIs across rivers in 47 Chinese cities," shares corresponding author Yanhao Zhang. "The compounds were found at concentrations from below detection limit to 119 ng/L, with a national median total concentration of 40 ng/L." Cyantraniliprole (CYTP) was the predominant contaminant, with a median concentration of 17 ng/L and a 100% detection frequency. "The chemical composition patterns varied by regions," says Zhang. "CYTP contributed most in southern basins, while broflanilide (BFA) made a larger contribution in northern basins." Local crop-planting patterns and crop-specific pesticide-use potentially shaped the regional pollution signatures. Land-use and meteorological variables did could not explain the differences of nationwide distribution. Notably, there was a mismatch between concentration and ecological risk. "BFA was not the most abundant pollutant, yet it became the main screening-level driver for the benthic midge Chironomus dilutus because its species-specific chronic effect threshold was much lower," shares Zhang. "BFA screening RQs exceeded 1...

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While diamide insecticides (DAIs) are new alternatives to conventional pesticides with improved selectivity, their environmental footprint needs an investigation. To that end, a nationwide study published in Environmental Chemistry and Ecotoxicology created a pollution snapshot to elucidate the widespread occurrence of DAIs in rivers across nine major Chinese basins, "We found four DAIs across rivers in 47 Chinese cities," shares corresponding author Yanhao Zhang. "The compounds were found at concentrations from below detection limit to 119 ng/L, with a national median total concentration of 40 ng/L." Cyantraniliprole (CYTP) was the predominant contaminant, with a median concentration of 17 ng/L and a 100% detection frequency. "The chemical composition patterns varied by regions," says Zhang. "CYTP contributed most in southern basins, while broflanilide (BFA) made a larger contribution in northern basins." Local crop-planting patterns and crop-specific pesticide-use potentially shaped the regional pollution signatures. Land-use and meteorological variables did could not explain the differences of nationwide distribution. Notably, there was a mismatch between concentration and ecological risk. "BFA was not the most abundant pollutant, yet it became the main screening-level driver for the benthic midge Chironomus dilutus because its species-specific chronic effect threshold was much lower," shares Zhang. "BFA screening RQs exceeded 1...

Researchers created a nationwide pollution snapshot of 4 diamide insecticides (DAIs) across 47 cities and 9 major Chinese river basins. Cyantraniliprole (CYTP) was the most abundant, but broflanilide…

Unsymmetrical bis(anilido)xanthene ligands, decorated by a 2,4,6-tricyclohexylanilido substituent and a less bulky anilido group, are readily prepared in moderate yields from a 4,5-dibromo-substituted...

An efficient and highly sensitive analytical method was developed for the simultaneous determination of neonicotinoids, benzopyrazoles, diamide insect…

Deal expands Indian group’s reach in diamide insecticides and adds branded formulations.

AbstractMosquito-vectored disease remains a significant global public health threat. One of the most significant barriers to mosquito control is the evolution of insecticide resistance and limited number of available insecticide classes. Isoxazolines and meta-diamides are two classes of insecticides targeting the gamma-aminobutyric acid (GABA) channel, a target site currently under-utilized in mosquito adulticides. Topical assays were conducted on laboratory colonies of the yellow fever mosquito, #Aedes aegypti L. (Diptera: Culicidae), and the common malaria mosquito, #Anopheles quadrimaculatus Say (Diptera: Culicidae), with three isoxazolines: afoxolaner, fluralaner, and fluxametamide, the meta-diamide, broflanilide, and the pyrethroid deltamethrin, a commonly used and well-studied insecticide for adult mosquito control. The insecticides were tested against susceptible and pyrethroid resistant Ae. aegypti and susceptible An. quadrimaculatus. Broflanilide and afoxolaner were found to be the most and least toxic, respectively, and all five compounds were more toxic to Ae. aegypti than An. quadrimaculatus. Cross-resistance to afoxolaner, fluralaner, and fluxametamide, and broflanilide was low or not found in the pyrethroid resistant CKR strain. Age ratios were low to insignificant, suggesting no difference in toxicity between younger and older #mosquitoes. While not as toxic as deltamethrin, the isoxazolines and meta-diamide, broflanilide, represent promising classes of insecticides that could be formulated for use against adult #mosquitoes, with the advantages of a favorable mammalian toxicological profile and no cross-resistance in pyrethroid resistant strains.

AbstractMosquito-vectored disease remains a significant global public health threat. One of the most significant barriers to mosquito control is the evolution of insecticide resistance and limited number of available insecticide classes. Isoxazolines and meta-diamides are two classes of insecticides targeting the gamma-aminobutyric acid (GABA) channel, a target site currently under-utilized in mosquito adulticides. Topical assays were conducted on laboratory colonies of the yellow fever mosquito, #Aedes aegypti L. (Diptera: Culicidae), and the common malaria mosquito, #Anopheles quadrimaculatus Say (Diptera: Culicidae), with three isoxazolines: afoxolaner, fluralaner, and fluxametamide, the meta-diamide, broflanilide, and the pyrethroid deltamethrin, a commonly used and well-studied insecticide for adult mosquito control. The insecticides were tested against susceptible and pyrethroid resistant Ae. aegypti and susceptible An. quadrimaculatus. Broflanilide and afoxolaner were found to be the most and least toxic, respectively, and all five compounds were more toxic to Ae. aegypti than An. quadrimaculatus. Cross-resistance to afoxolaner, fluralaner, and fluxametamide, and broflanilide was low or not found in the pyrethroid resistant CKR strain. Age ratios were low to insignificant, suggesting no difference in toxicity between younger and older #mosquitoes. While not as toxic as deltamethrin, the isoxazolines and meta-diamide, broflanilide, represent promising classes of insecticides that could be formulated for use against adult #mosquitoes, with the advantages of a favorable mammalian toxicological profile and no cross-resistance in pyrethroid resistant strains.

Reduction of MnII precursors with bulky diamide ligands provided access to a complex with the longest known Mn–Mn bond and to a rare example of N2 activation at high-spin MnI centers. While some instr...

Um estudo desenvolvido na Universidade Federal de Campina Grande (UFCG), em condições de laboratório, revela que a exposição das abelhas africanizadas aos inseticidas clorantraniliprole e ciantraniliprole reduz a sobrevivência e prejudica a capacidade de voo, fator essencial para atividades como coleta de néctar, polinização e retorno à colmeia. Os resultados serão detalhados no artigo “Survival and flight ability of Apis mellifera after exposure to anthranilic diamide insecticides”, publicado no Brazilian Journal of Biology. O trabalho, apoiado pela Capes (Fundação Coordenação de Aperfeiçoamento de Pessoal de Nível Superior), é resultado de uma pesquisa de mestrado da UFCG e foi orientado por Ewerton Marinho da Costa, engenheiro agrônomo, doutor em fitotecnia e docente da instituição. Segundo o pesquisador, a ideia foi responder a uma demanda crescente dos próprios agricultores. “A principal motivação foi gerar informações para auxiliar na conservação das abelhas em áreas agrícolas. Essa é uma demanda dos produtores, que precisam de subsídios em relação aos efeitos de inseticidas sobre as abelhas para adoção de estratégias mitigadoras de risco”, afirma Costa. A pesquisa comparou a mortalidade e as implicações motoras em abelhas expostas de duas maneiras: por pulverização direta e pela ingestão de dieta contaminada. As análises foram realizadas em laboratório. Os resultados mostraram baixa mortalidade para ambos os inseticidas, mas com diferenças importantes entre os modos de exposição. “Observamos que a exposição direta foi mais prejudicial às abelhas. Dentre os dois inseticidas, o ciantraniliprole causou os maiores percentuais de mortalidade”, relata o professor. Além da sobrevivência, a equipe avaliou a capacidade de voo das abelhas, essencial para a polinização e para a manutenção da colônia. Costa enfatiza que impactos subletais podem comprometer todo o ciclo de produção agrícola. “A capacidade de voo das abelhas foi afetada, mesmo que de maneira sutil, após a exposição direta às gotículas da pulverização com os inseticidas”, diz. A comparação foi feita com abelhas pulverizadas com água destilada. De acordo com o engenheiro agrônomo, estudar a capacidade de voo é crucial porque existem inseticidas que podem não proporcionar elevada mortalidade, mas podem prejudicar a mobilidade dos insetos. Qualquer prejuízo na mobilidade pode proporcionar falhas na polinização e redução drástica na obtenção de alimento. Os cientistas também se surpreenderam com alguns resultados. “Mesmo conhecendo o mecanismo de ação dos inseticidas, surpreendeu o fato da baixa mortalidade proporcionada em ambos os modos de exposição em comparação com o controle positivo. Outro ponto que gerou impacto foi o efeito adverso na capacidade de voo”, destaca Costa. “Os resultados serão utilizados para orientar produtores sobre formas de mitigação de riscos para abelhas em condições de campo, destacando os ingredientes ativos mais prejudiciais e aqueles que causam baixa ou praticamente nenhuma mortalidade”, diz. Apesar dos avanços, o pesquisador reforça que é necessário avaliar os inseticidas em condições reais de campo, levando em consideração fatores ambientais como temperatura, vento e horário de aplicação. Mais Lidas