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EFTA01110707 | EFTA01110723 LEONE, Paola compacta neurons with a HSV-I vector. Societyfor Neuroscience, 19: 328.2. 11. Rivest, R., Leeb, K., Leone, P., Wise, R.A. (1993) Microdialysis assessment of nucleus dopamine and metabolites during intravenous self administration; changes with unit dose. Society for Neuroscience, 19: 417.14. 12. During, M.J., Mirchandani, G., Leone, P., Williamson, A., de Lanerolle, N.C., Geschwind, M.D., Federoff, H.J. (1993) Intrahippocampal injection of a HSV-I vector expressing GLUR6 induces spontanous limbic seizures and CAI and CA3 hyperexcitability. American Epilepsy Society. Baltimore, MD. 13. Wise, R.A., Leone, P., Rivest, R.,Leeb, K. (1993) Elevation of nucleus accumbens dopamine, and metabolite levels during IV heroin self-administration: independence of unit dose and response requirement. College ofproblems of Drug Dependence, 55 Annual Scientific Meeting, Toronto, Canada, 14. Leone,P., and During, M.J. (1993) A HSV-I vector expressing unregulated PKC from the TH promotor improves spatial navigation performance following intrahippocampal injection in young adult rats. l4th ISN meeting, Montpellier, France. 15. Devine, D.P., Leone, P., Wise, R.A. (1993) Surgical preparation of striatal tissue facilitates early sampling in microdialysis and reveals an index of neuronal damage. Third International Symposium on Microdialysis and Allied Analytical Techniques, Current Separations, 12: 48. Montreal, Canada 16. Leone, P., During, M.J. (1993) Modulation of norepinephrine release by hippocampal injection of a PKC expressing HSV-1 vector influences spatial navigation performance in the adult rat. Third International Symposium on Microdialysis and Allied Analytical Techniques, Current Separations, 12: 79. Montreal, Canada 17. During, M.J., Kaplitt, M.G., Leone, P., Davidson, B., Xiao, X., Samulski, R.J., Elsworth, J.D., Roth, R.H., Sladek, J.R., Redmond, D.E., O'Malley, K.L. (1994) AAV and adenovirus mediated transfer of human tyrosine hydroxylase into rat and primate brain. Cold Spring Harbor Meeting on Gene Therapy, abstr. 190. 18. Samulski, R., Xiao, X., Kaplitt, M., Leone, P., Pfaff, D., O'Malley, K., During, M. (1994) Generation of AAV vectors for transduction and expression in neuronal cells in vivo. Cold Spring Harbor Meeting on Gene Therapy, abstr. 9. 19. Leone, P., Sherwin, R.S., Davis, K.E., Wallace, E., Dragunow, M., During, M.J.(1994) Cognitive improvement and ICROX24 induction in the lateral amydgala after D-glucose administration. Societyfor Neuroscience, 20: 334.23. 20. Williamson, A, Telfeian, A.E., Leone, P., Federoff, H.J., During, M.J.(1994) Overexpression of GI R6 in rat hippocampi produces spontaneous non-synaptic bursting in vitro. Societyfor Neuroscience, 20: 680.3. 21. Kaplitt, M.G., Leone, P., Freese, A., Xiao, X., Pfaff, D.W., O'Malley, K.L., During, M.J.( 1994) Adeno-associated virus (AAV) vectors yield safe delivery and long-term expression of potentially therapeutic genes in the adult mammalian brain. Societyfor Neuroscience, 20: 602.11. 22. During, M.J., Kaplitt, M.G., Leone, P., Xiao, X., Elsworth, J.D., Roth, R.H., Sladek, J.R., Redmond, D.E. (1994) AAV mediated transfer of tyrosine hydroxylase and aromatic amino acid 17of 22 EFTA01110723
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