Time to Staphylococcus aureus blood culture positivity is a useful marker for infective endocarditis
This retrospective cohort study of >1700 cases of SAB suggests that if TTP > 13 hrs, the patient is unlikely to have endocarditis (NPV 96%, 95%CI 95-97)
academic.oup.com/cid/advance-... #IDSky
This retrospective cohort study of >1700 cases of SAB suggests that if TTP > 13 hrs, the patient is unlikely to have endocarditis (NPV 96%, 95%CI 95-97)
academic.oup.com/cid/advance-... #IDSky
December 21, 2024 at 4:07 PM
Time to Staphylococcus aureus blood culture positivity is a useful marker for infective endocarditis
This retrospective cohort study of >1700 cases of SAB suggests that if TTP > 13 hrs, the patient is unlikely to have endocarditis (NPV 96%, 95%CI 95-97)
academic.oup.com/cid/advance-... #IDSky
This retrospective cohort study of >1700 cases of SAB suggests that if TTP > 13 hrs, the patient is unlikely to have endocarditis (NPV 96%, 95%CI 95-97)
academic.oup.com/cid/advance-... #IDSky
Dental abscesses -> bacterial endocarditis -> long term IV antibiotics +/- valve replacement via open heart surgery = $$$$$$$$$$$
Low levels of fluoride added to water reduce chronic diseases, increase life expectancy, and increase quality of life, while reducing individual and societal costs. I don’t understand how stupid you have to be to not understand how this works and still feel so confident you would oppose those things
Two cities stopped adding fluoride to water. Long-term data showed how ending fluoridation adversely affected the health of the population.
www.sciencenews.org/article/fluo...
www.sciencenews.org/article/fluo...
May 4, 2025 at 10:38 PM
Dental abscesses -> bacterial endocarditis -> long term IV antibiotics +/- valve replacement via open heart surgery = $$$$$$$$$$$
🆕💫 Early oral stepdown therapy for infective endocarditis: an international cross-sectional survey on current use in clinical practice ESCMID Study Group for Bloodstream Infections, Endocarditis and Sepsis
#idsky #IEWiki
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
#idsky #IEWiki
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Early oral stepdown therapy for infective endocarditis: an international cross-sectional survey on current use in clinical practice
There is now strong evidence supporting early oral switch (EOS) from intravenous antibiotics in the treatment of infective endocarditis (IE). Our obje…
www.sciencedirect.com
February 17, 2025 at 4:50 AM
🆕💫 Early oral stepdown therapy for infective endocarditis: an international cross-sectional survey on current use in clinical practice ESCMID Study Group for Bloodstream Infections, Endocarditis and Sepsis
#idsky #IEWiki
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
#idsky #IEWiki
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Endocarditis has entered the chat
July 7, 2025 at 2:43 AM
Endocarditis has entered the chat
November 28, 2024 at 3:32 PM
Endocarditis therapy has long been based on opinions of eminent experts rather than high-quality evidence
🔥PUBLISHED🔥
Our editorial with Dr.Spellberg✨️
@dremilymcd.bsky.social
@drtoddlee.bsky.social
Endocarditis Therapy: The Move From Expert Opinion to Evidence
www.sciencedirect.com/science/arti...
🔥PUBLISHED🔥
Our editorial with Dr.Spellberg✨️
@dremilymcd.bsky.social
@drtoddlee.bsky.social
Endocarditis Therapy: The Move From Expert Opinion to Evidence
www.sciencedirect.com/science/arti...
November 25, 2024 at 4:26 PM
Endocarditis therapy has long been based on opinions of eminent experts rather than high-quality evidence
🔥PUBLISHED🔥
Our editorial with Dr.Spellberg✨️
@dremilymcd.bsky.social
@drtoddlee.bsky.social
Endocarditis Therapy: The Move From Expert Opinion to Evidence
www.sciencedirect.com/science/arti...
🔥PUBLISHED🔥
Our editorial with Dr.Spellberg✨️
@dremilymcd.bsky.social
@drtoddlee.bsky.social
Endocarditis Therapy: The Move From Expert Opinion to Evidence
www.sciencedirect.com/science/arti...
🆕🔥Streptococcal endocarditis: a meta-analysis of species dependant risk by 🌟s @drtoddlee.bsky.social
🌟Updated figure 🌟Infective endocarditis prevalence of streptococcal species vs. proportion of streptococcal species bacteraemia #idsky #EMIMCC
www.sciencedirect.com/science/arti...
🌟Updated figure 🌟Infective endocarditis prevalence of streptococcal species vs. proportion of streptococcal species bacteraemia #idsky #EMIMCC
www.sciencedirect.com/science/arti...
August 25, 2025 at 4:18 PM
🆕🔥Streptococcal endocarditis: a meta-analysis of species dependant risk by 🌟s @drtoddlee.bsky.social
🌟Updated figure 🌟Infective endocarditis prevalence of streptococcal species vs. proportion of streptococcal species bacteraemia #idsky #EMIMCC
www.sciencedirect.com/science/arti...
🌟Updated figure 🌟Infective endocarditis prevalence of streptococcal species vs. proportion of streptococcal species bacteraemia #idsky #EMIMCC
www.sciencedirect.com/science/arti...
What if quorum sensing doesn’t promote biofilms - but restrains it? 🤔
New work from @harisantypas.bsky.social shows that the Fsr QS system in Enterococcus faecalis acts as a brake on biofilm formation and pathogenesis during infective endocarditis (IE).
www.nature.com/articles/s41...
New work from @harisantypas.bsky.social shows that the Fsr QS system in Enterococcus faecalis acts as a brake on biofilm formation and pathogenesis during infective endocarditis (IE).
www.nature.com/articles/s41...
Loss of Fsr quorum sensing promotes biofilm formation and worsens outcomes in enterococcal infective endocarditis - Nature Communications
Infective endocarditis (IE) is an understudied biofilm-associated infection. Here, analyses of preclinical and clinical data reveal that the Fsr quorum sensing (QS) system of Enterococcus faecalis is ...
www.nature.com
February 23, 2026 at 6:16 AM
What if quorum sensing doesn’t promote biofilms - but restrains it? 🤔
New work from @harisantypas.bsky.social shows that the Fsr QS system in Enterococcus faecalis acts as a brake on biofilm formation and pathogenesis during infective endocarditis (IE).
www.nature.com/articles/s41...
New work from @harisantypas.bsky.social shows that the Fsr QS system in Enterococcus faecalis acts as a brake on biofilm formation and pathogenesis during infective endocarditis (IE).
www.nature.com/articles/s41...
This is why I will die on a hill that dental care IS healthcare and should be covered by your health insurance plan and not on a separate plan "option."
people.com/man-35-didnt...
people.com/man-35-didnt...
Man, 35, Didn’t Think His Toothache Was Anything Serious. Days Later, He Needed Open-Heart Surgery to Save His Life
A 35-year-old man in Australia was left fighting for his life, days after he developed a toothache, which led to sepsis and infective endocarditis. The latter required Luke Woodhouse to have open-hear...
people.com
September 14, 2026 at 12:59 PM
This is why I will die on a hill that dental care IS healthcare and should be covered by your health insurance plan and not on a separate plan "option."
people.com/man-35-didnt...
people.com/man-35-didnt...
59ème rétraction pour Raoult
Retraction: The Uptake of Apoptotic Cells Drives Coxiella burnetii Replication and Macrophage Polarization: A Model for Q Fever Endocarditis
Absence d'autorisation éthique, one more time.
journals.plos.org/plospathogen...
Retraction: The Uptake of Apoptotic Cells Drives Coxiella burnetii Replication and Macrophage Polarization: A Model for Q Fever Endocarditis
Absence d'autorisation éthique, one more time.
journals.plos.org/plospathogen...
Retraction: The Uptake of Apoptotic Cells Drives Coxiella burnetii Replication and Macrophage Polarization: A Model for Q Fever Endocarditis
journals.plos.org
May 13, 2026 at 7:28 AM
59ème rétraction pour Raoult
Retraction: The Uptake of Apoptotic Cells Drives Coxiella burnetii Replication and Macrophage Polarization: A Model for Q Fever Endocarditis
Absence d'autorisation éthique, one more time.
journals.plos.org/plospathogen...
Retraction: The Uptake of Apoptotic Cells Drives Coxiella burnetii Replication and Macrophage Polarization: A Model for Q Fever Endocarditis
Absence d'autorisation éthique, one more time.
journals.plos.org/plospathogen...
Time to Staphylococcus aureus Blood Culture Positivity as a risk marker of Infective Endocarditis: A Retrospective Cohort Study
✅ Just Accepted
#IDSky
✅ Just Accepted
#IDSky
Time to Staphylococcus aureus Blood Culture Positivity as a risk marker of Infective Endocarditis: A Retrospective Cohort Study
Endocarditis occurs in approximately 10-15% of patients with Staphylococcus aureus bacteremia. Short time to positivity (TTP) in blood culture flasks has been linked to endocarditis in smaller studies. This study evaluated the association between TTP and endocarditis in S. aureus bacteremia in a large cohort.
buff.ly
December 24, 2024 at 7:58 PM
Time to Staphylococcus aureus Blood Culture Positivity as a risk marker of Infective Endocarditis: A Retrospective Cohort Study
✅ Just Accepted
#IDSky
✅ Just Accepted
#IDSky
Something that popped out at me that I hadn't previously quite appreciated:
- slow growing NTM endocarditis <-> prosthetic valves
- fast growing NTM endocarditis <-> native valves
And overall mortality 44%!
#IDSky #clinmicro
- slow growing NTM endocarditis <-> prosthetic valves
- fast growing NTM endocarditis <-> native valves
And overall mortality 44%!
#IDSky #clinmicro
Nontuberculous Mycobacterial Infective Endocarditis: A Systematic Review of Clinical Characteristics and Outcomes
#IDSky
#IDSky
Nontuberculous Mycobacterial Infective Endocarditis: A Systematic Review of Clinical Characteristics and Outcomes
Infective endocarditis (IE) due to nontuberculous mycobacteria (NTM) is a rare infection, and several outbreaks have been reported in the last 2 decades.
buff.ly
December 14, 2024 at 10:38 PM
Something that popped out at me that I hadn't previously quite appreciated:
- slow growing NTM endocarditis <-> prosthetic valves
- fast growing NTM endocarditis <-> native valves
And overall mortality 44%!
#IDSky #clinmicro
- slow growing NTM endocarditis <-> prosthetic valves
- fast growing NTM endocarditis <-> native valves
And overall mortality 44%!
#IDSky #clinmicro
Time to Staphylococcus aureus Blood Culture Positivity as a Risk Marker of Infective Endocarditis: A Retrospective Cohort Study
#IDSky
#IDSky
Time to Staphylococcus aureus Blood Culture Positivity as a Risk Marker of Infective Endocarditis: A Retrospective Cohort Study
This study evaluated the association between TTP and endocarditis in SAB in a large cohort.
academic.oup.com
May 10, 2025 at 6:58 PM
Time to Staphylococcus aureus Blood Culture Positivity as a Risk Marker of Infective Endocarditis: A Retrospective Cohort Study
#IDSky
#IDSky
35 ème rétractation pour l'IHU et la 30ème pour Raoult! Bientôt dans le top 30 des plus rétractés !
RETRACTED ARTICLE: First Case of Q Fever Endocarditis Involving the Melody® Transcatheter Pulmonary Valve in an Afebrile Child
link.springer.com/article/10.1...
RETRACTED ARTICLE: First Case of Q Fever Endocarditis Involving the Melody® Transcatheter Pulmonary Valve in an Afebrile Child
link.springer.com/article/10.1...
RETRACTED ARTICLE: First Case of Q Fever Endocarditis Involving the Melody® Transcatheter Pulmonary Valve in an Afebrile Child - Pediatric Cardiology
Pediatric Cardiology -
link.springer.com
December 31, 2024 at 8:48 AM
35 ème rétractation pour l'IHU et la 30ème pour Raoult! Bientôt dans le top 30 des plus rétractés !
RETRACTED ARTICLE: First Case of Q Fever Endocarditis Involving the Melody® Transcatheter Pulmonary Valve in an Afebrile Child
link.springer.com/article/10.1...
RETRACTED ARTICLE: First Case of Q Fever Endocarditis Involving the Melody® Transcatheter Pulmonary Valve in an Afebrile Child
link.springer.com/article/10.1...
Blood culture–negative endocarditis has been associated with worse outcomes when compared with blood culture–positive endocarditis, because pathogen‐directed antimicrobial therapy and other management aspects have been difficult to achieve #idsky
🔥Just published 🔥
Blood Culture–Negative Endocarditis: A Scientific Statement From the American Heart Association: Endorsed by the International Society for Cardiovascular Infectious Diseases
Read the note about gentamicin/Rifampin in fig-3
www.ahajournals.org/doi/10.1161/...
Blood Culture–Negative Endocarditis: A Scientific Statement From the American Heart Association: Endorsed by the International Society for Cardiovascular Infectious Diseases
Read the note about gentamicin/Rifampin in fig-3
www.ahajournals.org/doi/10.1161/...
March 17, 2025 at 7:17 PM
Blood culture–negative endocarditis has been associated with worse outcomes when compared with blood culture–positive endocarditis, because pathogen‐directed antimicrobial therapy and other management aspects have been difficult to achieve #idsky
Candida Endocarditis: current perspectives on diagnosis and therapy
Ben-Ami Ronen, Bassetti Matteo, Bouza Emilio, Kosman Alex, Vena Antonio on behalf of @efisg-escmid.bsky.social
www.clinicalmicrobiologyandinfection.com/article/S119... #MedMycoSky #IDSky
Ben-Ami Ronen, Bassetti Matteo, Bouza Emilio, Kosman Alex, Vena Antonio on behalf of @efisg-escmid.bsky.social
www.clinicalmicrobiologyandinfection.com/article/S119... #MedMycoSky #IDSky
Candida Endocarditis: current perspectives on diagnosis and therapy
Candida infective endocarditis (CIE) is a rare but potentially devastating condition.
Although it accounts for only 1-1.5% of infective endocarditis cases, CIE carries
a high mortality rate (36-49%) a...
www.clinicalmicrobiologyandinfection.com
June 8, 2025 at 2:10 PM
Candida Endocarditis: current perspectives on diagnosis and therapy
Ben-Ami Ronen, Bassetti Matteo, Bouza Emilio, Kosman Alex, Vena Antonio on behalf of @efisg-escmid.bsky.social
www.clinicalmicrobiologyandinfection.com/article/S119... #MedMycoSky #IDSky
Ben-Ami Ronen, Bassetti Matteo, Bouza Emilio, Kosman Alex, Vena Antonio on behalf of @efisg-escmid.bsky.social
www.clinicalmicrobiologyandinfection.com/article/S119... #MedMycoSky #IDSky
Nontuberculous Mycobacterial Infective Endocarditis: A Systematic Review of Clinical Characteristics and Outcomes
#IDSky
#IDSky
Nontuberculous Mycobacterial Infective Endocarditis: A Systematic Review of Clinical Characteristics and Outcomes
Infective endocarditis (IE) due to nontuberculous mycobacteria (NTM) is a rare infection, and several outbreaks have been reported in the last 2 decades.
buff.ly
December 14, 2024 at 10:11 PM
Nontuberculous Mycobacterial Infective Endocarditis: A Systematic Review of Clinical Characteristics and Outcomes
#IDSky
#IDSky
Straks voor de eerste keer naar de nierfalen-poli (nefrologie). Onderzoek naar 'lekkend nierfilters'. Weer wat nieuws of een nasleep van mijn endocarditis/nieuwe hartklep? 🫀
July 17, 2026 at 6:06 AM
Straks voor de eerste keer naar de nierfalen-poli (nefrologie). Onderzoek naar 'lekkend nierfilters'. Weer wat nieuws of een nasleep van mijn endocarditis/nieuwe hartklep? 🫀
“If the infection progressed to endocarditis or severe sepsis, there was a good chance it would kill you. The fact that there is scant evidence of dental cavities killing Neanderthals or anyone else prior to about 12,000 years ago, maybe even earlier than that, says a lot about the role of diet.”
May 22, 2026 at 3:12 AM
“If the infection progressed to endocarditis or severe sepsis, there was a good chance it would kill you. The fact that there is scant evidence of dental cavities killing Neanderthals or anyone else prior to about 12,000 years ago, maybe even earlier than that, says a lot about the role of diet.”
April 5, 2025 at 12:53 PM
Short time to blood culture positivity (TTP) was an independent risk factor of infective endocarditis in this large (N=1703) Staphylococcus aureus bacteremia cohort. TTP is useful for endocarditis risk stratification #idsky #EMIMCC
🆕💫Retrospective Cohort Study
Time to Staphylococcus aureus Blood Culture Positivity as a risk marker of IE
Short TTP was associated wit IE
NPV >95% suggests that TTP>13h can be used to risk stratify pts with SAB #idsky #EMIMCC
academic.oup.com/cid/article/...
academic.oup.com/cid/advance-...
Time to Staphylococcus aureus Blood Culture Positivity as a risk marker of IE
Short TTP was associated wit IE
NPV >95% suggests that TTP>13h can be used to risk stratify pts with SAB #idsky #EMIMCC
academic.oup.com/cid/article/...
academic.oup.com/cid/advance-...
Time to Staphylococcus aureus Blood Culture Positivity as a risk marker of Infective Endocarditis: A Retrospective Cohort Study
Short time to blood culture positivity (TTP) was an independent risk factor of infective endocarditis in this large (N=1703) Staphylococcus aureus bacterem
academic.oup.com
December 23, 2024 at 4:19 AM