#flozinate
should we screen for CKD in the general population?

Finally, flozins, finerenone and GLP1s allow a good cost-effectiveness case

www.nephjc.com/news/2025/7/... for #NephJC shorts

Time to stop just being dialysis-ologists and flozinate, glipinate!

#NephSky
NephJC Shorts: Should we Screen for Kidney Disease? — NephJC
Should we screen for CKD?
www.nephjc.com
July 31, 2025 at 5:45 PM
As ridiculous as CKD staging is, we have nothing on this thing of utter beauty

www.ahajournals.org/doi/10.1161/...

We are all stage A HF! Flozinate everyone. GDMT on the drinking water.

#medsky #cardiosky

/s
July 3, 2026 at 12:21 AM
Effectiveness of Empagliflozin vs Dapagliflozin for Kidney Outcomes in Type 2 Diabetes by Drs. Bonnesen, Schmidt et al.

In a nationwise Danish cohort study, type 2 DM patients had similar kidney outcome with empagliflozin and dapagliflozin.

jamanetwork.com/journals/jam...
January 22, 2025 at 8:10 PM
Agree
Probiotics, prebiotics - all mostly expensive scams until proven otherwise

Use the money to flozinate, use RAASi, hopefully GLP1RAs

#NephJC
October 15, 2025 at 1:30 AM
10/10
Final #nephjc thoughts

✳️ The 🔑 takeaway from this study is straightforward 👉 initiate #SGLT2i early, ensure consistent therapy, & recognize that the protective effects are not sustained after discontinuation.

Flozinate early and persist with flozination.
November 11, 2024 at 5:20 PM
Flozinate GOAT #NephJC
a black background with the words goat in different colors
ALT: a black background with the words goat in different colors
media.tenor.com
May 28, 2025 at 1:25 AM
Optimist: the cup is half full

Pessimist: the cup is half empty

Cardiologist: EF is preserved at 50%, but filling pressure is elevated, the cup has HFpEF. Give the patient diuretics and flozinate
Optimist: the cup is half full

Pessimist: the cup is half empty

ER doctor: I don’t have time for this, why don’t you two talk to each other and tell me which one of you is admitting the cup?
Optimist: the cup is half full

Pessimist: the cup is half empty

Palliative care doctor: You still have a significant amount of liquid in your cup. Let’s work together to make sure you can savor every last drop
September 15, 2024 at 8:13 AM
Agree with this algorithm from evidence.nejm.org/doi/full/10.... ($$$ or sub reqd)

Flozinate and Glipinate

Metformin only if these are not appropriate or possible

All else comes later
September 16, 2025 at 1:45 PM
Hopefully dialysis will contract ( @ericweinhandl.bsky.social @christosargyrop.bsky.social ) as we flozinate and glipinate and then we will have no choice but to step outside the dialysis addiction

#NephJC
January 8, 2025 at 2:27 AM
Sarcomeres vs nephrons? No way, says the awesome CardioRenal collaboration happening at @luriechildrens.bsky.social. Thanks @kidney-kula.bsky.social for a fantastic Grand Rounds on the interplay of kidney and heart health! 🫘🤝🏻🫀 — and may we all flozinate freely!
January 31, 2025 at 3:29 PM
Still another reason for SGLT-Inhibitors: ATTR-CM

www.jacc.org/doi/10.1016/...

#CardioSky #MedSky
@christosargyrop.bsky.social @hswapnil.bsky.social
Should we just #Flozinate the water?
December 4, 2024 at 2:46 PM
Just flozinate all the time when there is any hint of cardiovascular renal disease
March 30, 2025 at 12:55 AM
Exactly my question! Flozinate first.
August 21, 2026 at 9:08 PM
💊 The rise of #flozinate‼️
Slow 🐢 CKD progression ➡️protect kidneys, 📉 CV risk, & delay renal failure.

Dive in the power of #glipinate and #flozinate synergy! #nefroneando #NephSky #MedSky @theisn.org
𝗦𝗔𝗩𝗘 𝗧𝗛𝗘 𝗗𝗔𝗧𝗘 for the ISN Africa Regional Board Webinar: "SGLT2 inhibitors: a double gain for Nephrology."

🗣️ Faiçal Jarrayae, Valerie Luyckx, Nicola Wearne
👤 Fatiu Arogundade, Mohamed Salah
🗓️ January 14
🕒 2 pm CET
🔗 Free registration: ow.ly/Wchx50UBitS
January 8, 2025 at 1:10 PM
As one of the original flozinators it so maddening to see nephrologists flozinate *instead* of using immunosuppresants, dz modifying therapies in nonDM CKD. Consider a thought experiment in transplant: proteinuria is often how we pick up ABMR & an SGLT2i is the wrong answer. Now do IgAN, SLE,C3G etc
November 10, 2025 at 2:18 PM
No one should

I remember being mobbed by dietitians in Argentina who are believers in this costly approach (after #ISNWCN debate)

Outdated therapy.

Move on and flozinate instead

#NephJC
October 15, 2025 at 1:18 AM
March 29, 2025 at 2:23 AM
@kevinyau.bsky.social GLP1 agonist master Jedi presenting at #ERA25.

💉GLP1 agonist reduce ED visits and hospitalizations!!!

📉Awesome methods. Best of the session:

💊DDP4 for comparison, IPTW, ICES data. Ticking all the right boxes (EPI nerd).

💊Only 40% on SGLT2i!!! We should flozinate more!!!
June 5, 2025 at 9:49 AM
Hi, this is Assad , Nephrologist and transplant physician from India.
No COI.

We have a small cohort of transplant recipients whom we Flozinate, primarily for Proteinuria.

#NephJC
February 11, 2026 at 2:29 AM
November 20, 2024 at 1:51 AM
MedPage Today @medpagetoday.com quotes @brianrifkin.bsky.social et al on CKM guidelines/staging

www.medscape.com/s/viewarticl...

I do think CKM is a fake made up condition & the staging is a terrible idea

Flozinate, glipinate - but shoving another disease and staging and guideline? Count me out!
Grumblings Over CKM Guideline Not Warranted, Experts Say
Experts push back against concerns of overmedicalization and confusing staging with the new AHA/ACC guideline on cardiovascular-kidney-metabolic syndrome.
www.medscape.com
July 18, 2026 at 1:44 AM
MERCURI-2 has landed at #NephJC 🛬
📍Does it challenge the way we #flozinate before surgery?
#nephsky #medsky
VA by @manoleaandreea.bsky.social @nephjc.bsky.social
Excited for SGLT2 inhibitors to prevent AKI in CV surgery patients? So were we... until we got past the title.
This week we're talking about "that JAMA paper "🙃
#NephJC #NephSky
Here's the VA by @ManoleaA
www.nephjc.com/news/2026/8/17/mercuri-the-visual-abstract
MERCURI-2: The Visual Abstract — NephJC
Does MERCURI-2 challenge how we use SGLT2i in post-operative patients?
www.nephjc.com
August 17, 2026 at 4:28 PM
Have not had a charging cable for months. New one just arrived so I'll always know it's time to flozinate
@christosargyrop.bsky.social @hswapnil.medsky.social @jordybc.bsky.social @hvanspall.bsky.social @drmarthagulati.bsky.social
August 16, 2025 at 12:29 AM