The research team suggests that some people exposed to HCMV develop a chronic intestinal infection. The virus then enters the bloodstream or travels through the vagus nerve to the brain. CMV may contribute to the development of Alzheimer’s disease.
neurosciencenews.com/hcmv-virus-a...
neurosciencenews.com/hcmv-virus-a...
Chronic Gut Virus May Play a Role in Alzheimer’s Development - Neuroscience News
Researchers have linked chronic intestinal infections caused by cytomegalovirus (HCMV) to a unique subtype of Alzheimer’s disease.
neurosciencenews.com
December 24, 2024 at 11:24 PM
The research team suggests that some people exposed to HCMV develop a chronic intestinal infection. The virus then enters the bloodstream or travels through the vagus nerve to the brain. CMV may contribute to the development of Alzheimer’s disease.
neurosciencenews.com/hcmv-virus-a...
neurosciencenews.com/hcmv-virus-a...
this is vital research about the interaction of sars-cov-2 with human cytomegalovirus. I lack standing to comment on any implications -- I read papers like this in the late 80s, but not many after that -- but that sars-cov-2 can "reactivate" hcmv from latency seems to my layman's mind v. troubling
SARS-CoV-2 encoded ORF3a interacts with YY1 to promote latent HCMV reactivation
journals.plos.org/plospathogen...
journals.plos.org/plospathogen...
SARS-CoV-2 encoded ORF3a interacts with YY1 to promote latent HCMV reactivation
Author summary Although the WHO has declared the COVID-19 pandemic over, the impact of the pandemic on people still exists, especially the long-term symptoms known as post-acute sequelae or long COVID...
journals.plos.org
July 17, 2025 at 4:19 PM
this is vital research about the interaction of sars-cov-2 with human cytomegalovirus. I lack standing to comment on any implications -- I read papers like this in the late 80s, but not many after that -- but that sars-cov-2 can "reactivate" hcmv from latency seems to my layman's mind v. troubling
The @who.int cancer agency just added cytomegalovirus (HCMV) and hepatitis D virus (HDV) to the growing list of viruses officially linked to cancer. That brings the number of known cancer-associated viruses to 10.
www.iarc.who.int/news-events/...
www.iarc.who.int/news-events/...
<em>IARC Monographs</em> evaluation of the carcinogenicity of hepatitis D virus, human cytomegalovirus, and Merkel cell polyomavirus
www.iarc.who.int
July 14, 2025 at 8:48 PM
The @who.int cancer agency just added cytomegalovirus (HCMV) and hepatitis D virus (HDV) to the growing list of viruses officially linked to cancer. That brings the number of known cancer-associated viruses to 10.
www.iarc.who.int/news-events/...
www.iarc.who.int/news-events/...
Oh, HEY, this is both really good news (A stronger causative pathway and something we can potentially vaccinate against) and potentially very scary. Alzheimers as a potential Long HCMV.
www.azcentral.com/story/news/l...
www.azcentral.com/story/news/l...
ASU researchers find possible link between virus, almost 50% of Alzheimer’s cases
Research by the ASU-Banner Neurodegenerative Research Center proposes that a common herpes virus may travel through the body to the brain.
www.azcentral.com
February 20, 2025 at 1:13 AM
Oh, HEY, this is both really good news (A stronger causative pathway and something we can potentially vaccinate against) and potentially very scary. Alzheimers as a potential Long HCMV.
www.azcentral.com/story/news/l...
www.azcentral.com/story/news/l...
1/ BREAKING 👉A new study published in Nature Communications has unveiled a crucial connection between chronic #infection with Cytomegalovirus (HCMV), and the development of #Alzheimer’s disease in certain individuals: polybio.org/new-research...
New research illuminates link between chronic infection and Alzheimer’s Disease, paving the way for potential antiviral treatment - PolyBio Research Foundation
A new study published in Nature Communications has unveiled a crucial connection between chronic infection with Cytomegalovirus (HCMV), and the development...
polybio.org
December 20, 2024 at 7:57 PM
1/ BREAKING 👉A new study published in Nature Communications has unveiled a crucial connection between chronic #infection with Cytomegalovirus (HCMV), and the development of #Alzheimer’s disease in certain individuals: polybio.org/new-research...
HCMV infection depends on EGLN1-mediated mitochondrial activation to increase dNTP pools for viral DNA replication
www.cell.com/cell-reports...
www.cell.com/cell-reports...
HCMV infection depends on EGLN1-mediated mitochondrial activation to increase dNTP pools for viral DNA replication
Simpson et al. report that HCMV utilizes EGLN1 to upregulate mitochondrial metabolism
to support viral replication. EGLN1 is required for viral induction of dNTP synthesis
to support viral DNA replica...
www.cell.com
May 21, 2026 at 12:42 PM
HCMV infection depends on EGLN1-mediated mitochondrial activation to increase dNTP pools for viral DNA replication
www.cell.com/cell-reports...
www.cell.com/cell-reports...
#HiSciSky ! I'm a postdoc at UW-Madison studying how host-virus interactions influence HCMV infectivity, happy to move to this place. #lovevirology
October 31, 2023 at 5:08 PM
#HiSciSky ! I'm a postdoc at UW-Madison studying how host-virus interactions influence HCMV infectivity, happy to move to this place. #lovevirology
SARS-CoV-2 encoded ORF3a interacts with YY1 to promote latent HCMV reactivation
journals.plos.org/plospathogen...
journals.plos.org/plospathogen...
SARS-CoV-2 encoded ORF3a interacts with YY1 to promote latent HCMV reactivation
Author summary Although the WHO has declared the COVID-19 pandemic over, the impact of the pandemic on people still exists, especially the long-term symptoms known as post-acute sequelae or long COVID...
journals.plos.org
July 17, 2025 at 4:01 PM
SARS-CoV-2 encoded ORF3a interacts with YY1 to promote latent HCMV reactivation
journals.plos.org/plospathogen...
journals.plos.org/plospathogen...
Chronic Gut Virus May Play a Role in Alzheimer’s Development - neurosciencenews.com/hcmv-virus-a... via @neurosciencenew
Chronic Gut Virus May Play a Role in Alzheimer’s Development - Neuroscience News
Researchers have linked chronic intestinal infections caused by cytomegalovirus (HCMV) to a unique subtype of Alzheimer’s disease.
neurosciencenews.com
December 22, 2024 at 4:01 AM
Chronic Gut Virus May Play a Role in Alzheimer’s Development - neurosciencenews.com/hcmv-virus-a... via @neurosciencenew
A #cytomegalovirus-encoded lncRNA blocks cell-cycle progression.
HCMV lncRNA RNA2.7 stabilizes host mRNAs & enforces G1–S arrest, boosting viral replication through mRNA control & cell‑cycle blockade.
www.sciencedirect.com/science/arti... #virology #MicroSky
HCMV lncRNA RNA2.7 stabilizes host mRNAs & enforces G1–S arrest, boosting viral replication through mRNA control & cell‑cycle blockade.
www.sciencedirect.com/science/arti... #virology #MicroSky
March 28, 2026 at 7:15 PM
A #cytomegalovirus-encoded lncRNA blocks cell-cycle progression.
HCMV lncRNA RNA2.7 stabilizes host mRNAs & enforces G1–S arrest, boosting viral replication through mRNA control & cell‑cycle blockade.
www.sciencedirect.com/science/arti... #virology #MicroSky
HCMV lncRNA RNA2.7 stabilizes host mRNAs & enforces G1–S arrest, boosting viral replication through mRNA control & cell‑cycle blockade.
www.sciencedirect.com/science/arti... #virology #MicroSky
Human cytomegalovirus (HCMV) infects 60%–90% of the population worldwide. In #JVirology, researchers show that the HCMV-encoded protein UL22A is necessary for reactivation from latency in CD34+ hematopoietic progenitor cells and in a humanized mouse model. asm.social/32g
August 6, 2026 at 11:29 AM
Human cytomegalovirus (HCMV) infects 60%–90% of the population worldwide. In #JVirology, researchers show that the HCMV-encoded protein UL22A is necessary for reactivation from latency in CD34+ hematopoietic progenitor cells and in a humanized mouse model. asm.social/32g
💯
It’s also worth considering that the same may be true of HCMV. There is developing data that HCMV is beneficial to immune priming and this work from @bpfairfax.bsky.social is impressive and thought provoking
pubmed.ncbi.nlm.nih.gov/40269332/
It’s also worth considering that the same may be true of HCMV. There is developing data that HCMV is beneficial to immune priming and this work from @bpfairfax.bsky.social is impressive and thought provoking
pubmed.ncbi.nlm.nih.gov/40269332/
Checking your browser - reCAPTCHA
pubmed.ncbi.nlm.nih.gov
April 22, 2026 at 4:51 PM
💯
It’s also worth considering that the same may be true of HCMV. There is developing data that HCMV is beneficial to immune priming and this work from @bpfairfax.bsky.social is impressive and thought provoking
pubmed.ncbi.nlm.nih.gov/40269332/
It’s also worth considering that the same may be true of HCMV. There is developing data that HCMV is beneficial to immune priming and this work from @bpfairfax.bsky.social is impressive and thought provoking
pubmed.ncbi.nlm.nih.gov/40269332/
Excited to share our latest paper on how macroH2A is targeted by IE1 during HCMV infection- featured as an editors pick in Nature Communications! Fantastic work by Laurel and team!!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Human cytomegalovirus induces neuronal gene expression through IE1 for viral maturation - Nature Communications
HCMV rearranges the host cell to produce infectious virus but molecular details are still unclear. Here, the authors analyze the transcriptome of infected cells and show that HCMV turns on dormant neu...
www.nature.com
August 23, 2025 at 1:40 PM
Excited to share our latest paper on how macroH2A is targeted by IE1 during HCMV infection- featured as an editors pick in Nature Communications! Fantastic work by Laurel and team!!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
ATRX restricts Human Cytomegalovirus (HCMV) viral DNA replication through heterochromatinization and minimizes unpackaged viral genomes
journals.plos.org/plospathogen...
journals.plos.org/plospathogen...
ATRX restricts Human Cytomegalovirus (HCMV) viral DNA replication through heterochromatinization and minimizes unpackaged viral genomes
Author summary Viruses infect host cells and often kill them, so cells encode proteins geared to protect them from viral predators. Viruses, as obligate intracellular parasites, rely on host cell prot...
journals.plos.org
October 2, 2025 at 8:09 PM
ATRX restricts Human Cytomegalovirus (HCMV) viral DNA replication through heterochromatinization and minimizes unpackaged viral genomes
journals.plos.org/plospathogen...
journals.plos.org/plospathogen...
Chronic Gut Virus May Play a Role in Alzheimer’s Development
neurosciencenews.com/hcmv-virus-a...
While HCMV infection is common and typically harmless, this study found that it may cause chronic brain inflammation in certain individuals
neurosciencenews.com/hcmv-virus-a...
While HCMV infection is common and typically harmless, this study found that it may cause chronic brain inflammation in certain individuals
Chronic Gut Virus May Play a Role in Alzheimer’s Development - Neuroscience News
Researchers have linked chronic intestinal infections caused by cytomegalovirus (HCMV) to a unique subtype of Alzheimer’s disease.
neurosciencenews.com
December 21, 2024 at 1:53 AM
Chronic Gut Virus May Play a Role in Alzheimer’s Development
neurosciencenews.com/hcmv-virus-a...
While HCMV infection is common and typically harmless, this study found that it may cause chronic brain inflammation in certain individuals
neurosciencenews.com/hcmv-virus-a...
While HCMV infection is common and typically harmless, this study found that it may cause chronic brain inflammation in certain individuals
Excited to share this preprint! In 2016, Caló et al /GSK reported a gL-free envelope gH complex in HCMV virions. We found a 3rd part of the complex— the part that likely binds receptors, show a role in entry & thanks to our collaborators, solved a cryo-EM structure www.biorxiv.org/content/10.1...
A noncanonical glycoprotein H complex enhances cytomegalovirus entry
Human cytomegalovirus (HCMV) causes severe birth defects, lifelong health complications, and $4 billion in annual costs in the United States alone. A major challenge in vaccine design is the incomplet...
www.biorxiv.org
October 14, 2024 at 2:53 AM
Excited to share this preprint! In 2016, Caló et al /GSK reported a gL-free envelope gH complex in HCMV virions. We found a 3rd part of the complex— the part that likely binds receptors, show a role in entry & thanks to our collaborators, solved a cryo-EM structure www.biorxiv.org/content/10.1...
Selective decoupling of IgG1 binding to viral Fc receptors restores antibody-mediated NK cell activation against HCMV
Selective decoupling of IgG1 binding to viral Fc receptors restores antibody-mediated NK cell activation against HCMV
Antibodies targeting human cytomegalovirus (HCMV) are undermined by viral immune evasion strategies, including capture of the Fc. Qerqez et al. engineer human Fc variants with markedly reduced binding to two viral Fc receptors. Engineered antibodies mediate enhanced CD16A-activation against HCMV-infected fibroblasts and limit viral spread more effectively than non-engineered antibodies.
dlvr.it
December 15, 2025 at 12:24 AM
Selective decoupling of IgG1 binding to viral Fc receptors restores antibody-mediated NK cell activation against HCMV
Une visite riche en échanges à Ho Chi Minh Ville🇻🇳
Retour sur deux jours de dialogue constructif avec les collègues à HCMV
🔹 Une section syndicale dynamique, mais des défis importants :charge de travail élevée, dysfonctionnements RH et instances de dialogue social à revitaliser
@snesfsu.bsky.social
Retour sur deux jours de dialogue constructif avec les collègues à HCMV
🔹 Une section syndicale dynamique, mais des défis importants :charge de travail élevée, dysfonctionnements RH et instances de dialogue social à revitaliser
@snesfsu.bsky.social
January 22, 2025 at 4:02 AM
Une visite riche en échanges à Ho Chi Minh Ville🇻🇳
Retour sur deux jours de dialogue constructif avec les collègues à HCMV
🔹 Une section syndicale dynamique, mais des défis importants :charge de travail élevée, dysfonctionnements RH et instances de dialogue social à revitaliser
@snesfsu.bsky.social
Retour sur deux jours de dialogue constructif avec les collègues à HCMV
🔹 Une section syndicale dynamique, mais des défis importants :charge de travail élevée, dysfonctionnements RH et instances de dialogue social à revitaliser
@snesfsu.bsky.social
RRIDs were included in this in mBio paper. We value the author's support of reproducibility. #methodsmatter #STMpublishing #accelerateopenscience
HCMV US30 induces TMED10-DRP1-mediated mitochondrial fission and apoptosis to promote viral multiplication
Read the full paper: HCMV US30 induces TMED10-DRP1-mediated mitochondrial fission and apoptosis to promote viral multiplication
doi.org
October 2, 2026 at 7:01 AM
RRIDs were included in this in mBio paper. We value the author's support of reproducibility. #methodsmatter #STMpublishing #accelerateopenscience
Prevalence of EBV, HHV6, HCMV, HAdV, SARS-CoV-2, and Autoantibodies to Type I Interferon in Sputum from Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Patients
Ulf Hannestad 1, Annika Allard 2, Kent Nilsson 3, Anders Rosén 1,* pmc.ncbi.nlm.nih.gov/articles/PMC... #ME/CFS
Ulf Hannestad 1, Annika Allard 2, Kent Nilsson 3, Anders Rosén 1,* pmc.ncbi.nlm.nih.gov/articles/PMC... #ME/CFS
Prevalence of EBV, HHV6, HCMV, HAdV, SARS-CoV-2, and Autoantibodies to Type I Interferon in Sputum from Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Patients
An exhausted antiviral immune response is observed in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and post-SARS-CoV-2 syndrome, also termed long COVID. In this study, potential mechani...
pmc.ncbi.nlm.nih.gov
April 12, 2025 at 9:05 PM
Prevalence of EBV, HHV6, HCMV, HAdV, SARS-CoV-2, and Autoantibodies to Type I Interferon in Sputum from Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Patients
Ulf Hannestad 1, Annika Allard 2, Kent Nilsson 3, Anders Rosén 1,* pmc.ncbi.nlm.nih.gov/articles/PMC... #ME/CFS
Ulf Hannestad 1, Annika Allard 2, Kent Nilsson 3, Anders Rosén 1,* pmc.ncbi.nlm.nih.gov/articles/PMC... #ME/CFS
6/ “The study offers compelling evidence that chronic HCMV infection could be a driver of Alzheimer's disease in a subset of patients," said PolyBio Research Foundation Vice President Dr. Michael VanElzakker.
December 20, 2024 at 7:57 PM
6/ “The study offers compelling evidence that chronic HCMV infection could be a driver of Alzheimer's disease in a subset of patients," said PolyBio Research Foundation Vice President Dr. Michael VanElzakker.
#NoirvemberChallenge — anyone here seen Norwegian noir DEATH IS A CARESS by Edith Carlmar? I’ve always longed to see it and turns out it is on YouTube with English subtitles. So…now you know what I’ll be doing this weekend!
www.youtube.com/watch?v=hcmv...
www.youtube.com/watch?v=hcmv...
November 22, 2025 at 4:49 AM
#NoirvemberChallenge — anyone here seen Norwegian noir DEATH IS A CARESS by Edith Carlmar? I’ve always longed to see it and turns out it is on YouTube with English subtitles. So…now you know what I’ll be doing this weekend!
www.youtube.com/watch?v=hcmv...
www.youtube.com/watch?v=hcmv...
Prevalence of EBV, HHV6, HCMV, HAdV, SARS-CoV-2, and Autoantibodies to Type I Interferon in Sputum from Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Patients
pmc.ncbi.nlm.nih.gov/articles/PMC...
Image from September AMMES newsletter
#PwME #MEcfs #CFS
pmc.ncbi.nlm.nih.gov/articles/PMC...
Image from September AMMES newsletter
#PwME #MEcfs #CFS
September 6, 2025 at 12:30 AM
Prevalence of EBV, HHV6, HCMV, HAdV, SARS-CoV-2, and Autoantibodies to Type I Interferon in Sputum from Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Patients
pmc.ncbi.nlm.nih.gov/articles/PMC...
Image from September AMMES newsletter
#PwME #MEcfs #CFS
pmc.ncbi.nlm.nih.gov/articles/PMC...
Image from September AMMES newsletter
#PwME #MEcfs #CFS