Soil-Transmitted Helminthiases, Alabama, USA

A monitoring and evaluation manual to guide managers of schistosomiasis and soil-transmitted helminthiases control programmes towards the elimination of these diseases as public health problems.

Helminthiasis is a neglected public health challenge threatening North Koreans. However, there is no precise estimate on the burden of helminthiasis in the region. This study therefore reviewed existi...

Soil-transmitted helminthiases (STH), including trichuriasis, pose a significant global burden, affe

Soil-transmitted helminthiases (STH), including trichuriasis, pose a significant global burden, affe

The global threat of neglected tropical diseases (NTDs) constitutes a public health issue in underdeveloped countries. Zoonotic helminthiases are the most common human NTD agents in developing countries in sub-Saharan Africa, Asia, and the Americas, causing a global burden of disease that exceeds th

Neglected tropical diseases primarily affect vulnerable populations in low-resource settings worldwide. In the United States, neglected tropical diseases such as Chagas, soil-transmitted helminthiases, and other infections historically affected immigrants but are increasingly relevant for US residents with climate change. We examined the pricing, prescribing rates, and supply of therapies used to treat neglected tropical diseases in the United States and their implications for accessibility and patient care.MethodsA retrospective analysis of prescription rates, wholesale acquisition costs, and shortages was conducted for 11 treatment products from 2019 to 2024, aggregating data from Symphony Metys, First Databank, NAVLIN, Red Book, and the University of Utah Drug Information Service.ResultsWhile prices for most neglected tropical diseases were stable, albendazole prices decreased by 78% while mebendazole prices rose by 60%. Miltefosine remained expensive at $48 000 per treatment course. There are limited manufacturers of neglected tropical disease treatments in the United States, increasing vulnerability to shortages.ConclusionsAddressing pricing irregularities and supply vulnerabilities requires legislative and policy interventions to enhance generic competition, expand public manufacturing, and strengthen supply chains. Such measures are critical to ensuring affordable and accessible treatment options for neglected tropical diseases in the United States.

Neglected tropical diseases primarily affect vulnerable populations in low-resource settings worldwide. In the US, neglected tropical diseases such as Chagas, soil-transmitted helminthiases, and other infections historically impacted immigrants but are increasingly relevant for US residents with climate change. We examined the pricing, prescribing rates, and supply of therapies used to treat neglected tropical diseases in the US and their implications for accessibility and patient care.MethodsA retrospective analysis of prescription rates, wholesale acquisition costs, and shortages was conducted for 11 treatment products from 2019 to 2024, aggregating data from Symphony Metys, First Databank, NAVLIN, Red Book, and the University of Utah Drug Information Service.ResultsWhile prices for most neglected tropical diseases were stable, albendazole prices decreased by 78%, while mebendazole prices rose by 60%. Miltefosine remained expensive at $48,000 per treatment course. There are limited manufacturers of neglected tropical disease treatments in the US, increasing vulnerability to shortages.ConclusionsAddressing pricing irregularities and supply vulnerabilities requires legislative and policy interventions to enhance generic competition, public manufacturing, and strengthen supply chains. Such measures are critical to ensuring affordable and accessible treatment options for neglected tropical diseases in the US.

A complex of ecological, phonological, and epidemiological zoning of the territory of Armenia has been conducted simultaneously on a group of soil-transmitted helminthiases ascariasis and whipworm disease (trichuriasis). Zones and terms of ...

A complex of ecological, phonological, and epidemiological zoning of the territory of Armenia has been conducted simultaneously on a group of soil-transmitted helminthiases ascariasis and whipworm disease (trichuriasis). Zones and terms of ...

Background Infections classified as group 1 biological carcinogens include the helminthiases caused by Schistosoma haematobium and Opisthorchis viverrini. The molecular mediators underlying the infect...