#hyperuricemia
🫘Hyperuricemia management in CKD

❌DO NOT use urate lowering drugs in CKD with asymptomatic Hyperuricemia

@nephjc.bsky.social @kdigo.org
#NephPearls #NephSky
February 16, 2025 at 12:16 PM
The medical check-up results are out... Hyperuricemia.

Bye-bye seafood.
July 27, 2026 at 1:09 AM
Ophthopedia Update: Metabolic Threat to Vision: Hyperuricemia-Associated Retinal Ganglion Cell Damage Through Inflammatory and Apoptotic Pathways: Publication date: Available online 2 October 2026

Source: Experimental Eye Research

Author(s): Danyi Qin, Fei Yu, Qingjian Li, Chaofeng Yu, Caihong…
Metabolic Threat to Vision: Hyperuricemia-Associated Retinal Ganglion Cell Damage Through Inflammatory and Apoptotic Pathways
Publication date: Available online 2 October 2026 Source: Experimental Eye Research Author(s): Danyi Qin, Fei Yu, Qingjian Li, Chaofeng Yu, Caihong Huang, Yi Han, Zuguo Liu
dlvr.it
October 3, 2026 at 11:57 AM
As expected it doesn’t do much

Hyperuricemia is a bystander, not on the causal pathway (so treat only if gout)

#ISNWCN
March 30, 2026 at 1:09 AM
Key insight:
🧠 1-year cognitive scores strongly predict outcomes years later
⚠️ AKI, hyperuricemia & ↑angiopoietin-2 → worse long-term cognition

Bottom line: we need early interventions + long-term follow-up for kids with severe malaria.
April 18, 2026 at 12:34 PM
오늘도 ㅈㅅ일보가 ㅈㅅ소리를 했습니다.

먼저 피인용 41회 논문을 가져오겠습니다. 내용은 웨이프로틴(유청단백질)이 혈중 요산수치를 개선했다는겁니다. 기본적으로다가 통풍은 요산때문에 생깁니다, 정확히는 퓨린이 대사된 물질이 요산인데, 이게 과도하게 남으면 결정화가 되어서 고통을 유발하는거죠.

여러 논문에 따르면 유청단백, 분리대두단백 모두 "초 저 퓨린 음식"이라 요산수치를 오히려 낮춥니다. 통풍이 있다면 적색육이 아니라 오히려 단백질 보충제로 단백질을 섭취해야 하는겁니다.

그럼 왜 저런 문제가 생길까요?
March 3, 2026 at 12:51 AM
Study: Elevated uric acid risk factor for poor outcomes in kids with severe #malaria

Hyperuricemia was tied to serious complications, a higher risk of death, and long-term cognitive impairment.

www.cidrap.umn.edu/m...

Photo: UN Development Programme / Flickr cc
January 29, 2025 at 5:51 PM
Trajectories of body roundness index and risk of incident hyperuricemia in middle-aged and older Chinese adults: evidence from the China Health and Retirement Longitudinal Study
Trajectories of body roundness index and risk of incident hyperuricemia in middle-aged and older Chinese adults: evidence from the China Health and Retirement Longitudinal Study
chuckyscarnage.tech.blog
October 2, 2026 at 11:57 AM
Certain strains of a bacterium found in the gut of some animals, Lactobacillus plantarum, are able to counter hyperuricemia, a condition caused by high levels of uric acid in the blood.
https://buff.ly/3Cr8xYO
November 20, 2024 at 9:59 PM
S-nitrosylation of PRDX2 worsens kidney injury in hyperuricemia, revealing it as a potential therapeutic target.

by Han F, Dong Y (...) Chen L et 6 al. in Free Radic Biol Med #MedSky

📖 read the article:
S-nitrosylation of peroxiredoxin 2 exacerbates hyperuricemia-induced renal injury through regulation of mitochondrial homeostasis
Protein S-nitrosylation (SNO), a redox-based posttranslational modification of cysteine thiols, plays a crucial role in various signaling pathways. Pe…
www.sciencedirect.com
March 25, 2025 at 2:02 AM
#GCAN2025 session on the microbiome and metabolomics

Federico Rey: hyperuricemia and gut microbiome targets (from the perspective of a microbiologist)

The microbiome is stable long term but there is a large interpersonal variability

#ACR25
October 23, 2025 at 6:44 PM
Hyperuricemia may be induced by excessive use of vitamin D supplements? Uh oh.
August 31, 2024 at 9:00 AM
Is there a bidirectional relationship between metabolic syndrome and hyperuricemia?

🔗 academic.oup.com/ajh/article/... 🔒
July 8, 2025 at 9:48 AM
Asymptomatic hyperuricemia in CKD: mechanisms and clinical implications ca. 2023 from @ckj-era.bsky.social @hjanders.bsky.social
#Nephpearls #NephSky

👉 pubmed.ncbi.nlm.nih.gov/37261000/
July 2, 2025 at 9:15 PM
International survey study of people with asymptomatic hyperuricemia looked at perceptions about hyperuricemia and urate-lowering therapy. Hyperuricemia was not well understood, and most perceived minimal consequences of asymptomatic hyperuricemia

AC&R
doi.org/10.1002/acr....

#Medsky
September 3, 2025 at 4:22 PM
Basically, no eating. But wait! Get this... Fasting is also a risk because it too makes hyperuricemia worse…
June 22, 2026 at 7:20 PM
The Gout, Hyperuricemia and Crystal-Associated Disease Network (GCAN) is delighted to announce that we are following the blue butterfly and transitioning from X to Bluesky.
November 15, 2024 at 11:53 PM
Animal-based low-carbohydrate #diets are linked to a greater risk of #hyperuricemia, a primary risk factor for #gout, while no association was observed for #plantbased low-carbohydrate diets: doi.org/10.1186/s129... #meat #nutrition #health #Korea
Associations of low-carbohydrate diets patterns with the risk of hyperuricemia: a national representative cross-sectional study in Korea - Nutrition Journal
Background The association between low-carbohydrate diets and hyperuricemia risk, a significant risk factor for gout and cardiometabolic morbidities, remains inconclusive, partly due to differing effe...
doi.org
April 16, 2025 at 8:16 PM
Xiangya Hyperuricemia Study: a rural community based cohort in China in which gut microbiome dysbiosis was studied in relation to hyperuricemia

pubmed.ncbi.nlm.nih.gov/34725964/

#2024GCAN #ACR24
November 13, 2024 at 6:18 PM
⭐️Florina Ionete - should the hyperuricemia threshold be lowered for women?

Examined gender-specific prevalence & RF for hyperuricemia among ppl from rural Romania 🇷🇴

#2024GCAN #ACR24
November 14, 2024 at 2:34 PM
#2024GCAN
Dr Jie Wei on the gut microbiome in hyperuricemia & gout

Studies on association of gut dysbiosis & gout (table)
#ACR24
November 13, 2024 at 6:18 PM
Review summarizes the characterization of gut dysbiosis in gout and identification of intestinal anaerobic purine-degrading bacteria, and discusses the potential of probiotic classes of ULT agents to aid treatment

In Arthritis & Rheumatology
doi.org/10.1002/art....
#Medsky #Gastrosky
January 23, 2025 at 1:36 PM
To manage hyperuricemia, it’s best to be vegetarian…

But you can’t have imitation meat due to the high yeast levels

And most breads are a no

And certain vegetables like mushrooms, asparagus, tomatoes, peas, & cauliflower are disallowed

And no fruits high in sugar

And you can’t have most dairy
June 22, 2026 at 7:20 PM
In the lead up to #ACR25 I will be virtually attending #GCAN2025

Remember to mute these hash tags if you don't want to be inundated with live posts.

This particular conference focuses on crystal associated diseases: gout, CPPD, BCP

g-can.swoogo.com/2025/8841622
October 22, 2025 at 11:15 AM