Disease Modeling in iPSC-Derived Human Bone Marrow Organoids
Work by Ermin Li, Ashley Zheng and Kehan Ren at Stony Brook University and Amy Ji at Columbia University.
#LifeSciences #Reproducibility #StemCell
Work by Ermin Li, Ashley Zheng and Kehan Ren at Stony Brook University and Amy Ji at Columbia University.
#LifeSciences #Reproducibility #StemCell
November 4, 2026 at 2:40 AM
Disease Modeling in iPSC-Derived Human Bone Marrow Organoids
Work by Ermin Li, Ashley Zheng and Kehan Ren at Stony Brook University and Amy Ji at Columbia University.
#LifeSciences #Reproducibility #StemCell
Work by Ermin Li, Ashley Zheng and Kehan Ren at Stony Brook University and Amy Ji at Columbia University.
#LifeSciences #Reproducibility #StemCell
An Isogenic iPSC Model of LMNA p.R482W Recapitulates Adipocyte Dysfunction in Familial Partial Lipodystrophy Type 2 https://www.biorxiv.org/content/10.64898/2026.10.29.760154v1
November 2, 2026 at 6:33 PM
An Isogenic iPSC Model of LMNA p.R482W Recapitulates Adipocyte Dysfunction in Familial Partial Lipodystrophy Type 2 https://www.biorxiv.org/content/10.64898/2026.10.29.760154v1
New paper co-authored by our CCP team!
www.sciencedirect.com/science/arti...
Our iPSC/NAM lab is also starting operations and offering research services. Explore opportunities to work with us:
www.phenogenomics.cz/nam/
#iPSC #NAMs
www.sciencedirect.com/science/arti...
Our iPSC/NAM lab is also starting operations and offering research services. Explore opportunities to work with us:
www.phenogenomics.cz/nam/
#iPSC #NAMs
November 3, 2026 at 1:12 PM
New paper co-authored by our CCP team!
www.sciencedirect.com/science/arti...
Our iPSC/NAM lab is also starting operations and offering research services. Explore opportunities to work with us:
www.phenogenomics.cz/nam/
#iPSC #NAMs
www.sciencedirect.com/science/arti...
Our iPSC/NAM lab is also starting operations and offering research services. Explore opportunities to work with us:
www.phenogenomics.cz/nam/
#iPSC #NAMs
🚨 $IPSC
Carr Douglas, a Officer, filed a notice of intent to sell 266 shares of common stock, valued at approximately $403.94, on 11/03/2026.
Carr Douglas, a Officer, filed a notice of intent to sell 266 shares of common stock, valued at approximately $403.94, on 11/03/2026.
SEC Filing: IPSC
Click to view the official SEC document.
www.sec.gov
November 3, 2026 at 8:32 PM
🚨 $IPSC
Carr Douglas, a Officer, filed a notice of intent to sell 266 shares of common stock, valued at approximately $403.94, on 11/03/2026.
Carr Douglas, a Officer, filed a notice of intent to sell 266 shares of common stock, valued at approximately $403.94, on 11/03/2026.
🔬 Job: Postdocs in Mitochondria & Neurodegeneration at Case Western Reserve University
Study how mitochondrial damage drives Alzheimer's, Parkinson's and ALS, using iPSC neurons and animal models.
📍 Cleveland, USA
⏰ Closes 25 Dec
www.dementiaresearcher.nihr.ac.uk/job/postdoct...
Study how mitochondrial damage drives Alzheimer's, Parkinson's and ALS, using iPSC neurons and animal models.
📍 Cleveland, USA
⏰ Closes 25 Dec
www.dementiaresearcher.nihr.ac.uk/job/postdoct...
Postdoctoral Fellow: Mitochondria in Neurodegeneration
Postdoctoral fellows wanted at Case Western Reserve University to study mitochondrial dysfunction in Alzheimer's, Parkinson's and ALS using iPSC models.
www.dementiaresearcher.nihr.ac.uk
November 1, 2026 at 4:54 PM
🔬 Job: Postdocs in Mitochondria & Neurodegeneration at Case Western Reserve University
Study how mitochondrial damage drives Alzheimer's, Parkinson's and ALS, using iPSC neurons and animal models.
📍 Cleveland, USA
⏰ Closes 25 Dec
www.dementiaresearcher.nihr.ac.uk/job/postdoct...
Study how mitochondrial damage drives Alzheimer's, Parkinson's and ALS, using iPSC neurons and animal models.
📍 Cleveland, USA
⏰ Closes 25 Dec
www.dementiaresearcher.nihr.ac.uk/job/postdoct...
How does APOE4 damage brain blood vessels?
Pericytes turn into fibronectin-secreting myofibroblasts that promote vascular amyloid, driven by TGF-β. Blocking TGF-β restored pericytes. Congrats to the Blanchard lab in Cell 👇🏻
https://doi.org/10.1016/j.cell.2026.08.058
Pericytes turn into fibronectin-secreting myofibroblasts that promote vascular amyloid, driven by TGF-β. Blocking TGF-β restored pericytes. Congrats to the Blanchard lab in Cell 👇🏻
https://doi.org/10.1016/j.cell.2026.08.058
November 4, 2026 at 2:26 PM
How does APOE4 damage brain blood vessels?
Pericytes turn into fibronectin-secreting myofibroblasts that promote vascular amyloid, driven by TGF-β. Blocking TGF-β restored pericytes. Congrats to the Blanchard lab in Cell 👇🏻
https://doi.org/10.1016/j.cell.2026.08.058
Pericytes turn into fibronectin-secreting myofibroblasts that promote vascular amyloid, driven by TGF-β. Blocking TGF-β restored pericytes. Congrats to the Blanchard lab in Cell 👇🏻
https://doi.org/10.1016/j.cell.2026.08.058
Gentamicin impairs nephron development in iPSC-derived kidney organoids and disrupts proximal tubular lysosomal function https://www.biorxiv.org/content/10.64898/2026.10.28.762495v1
November 3, 2026 at 6:01 PM
Gentamicin impairs nephron development in iPSC-derived kidney organoids and disrupts proximal tubular lysosomal function https://www.biorxiv.org/content/10.64898/2026.10.28.762495v1
Beautiful mural in Dublin by Emmalene Blake honouring Gavin Bazunu for his courage in refusing to play against apartheid Israel's team in the Nations League. We will always remember the people who stood with the Palestinian people, who were on the right side of history. #FreePalestine 🇵🇸
October 31, 2026 at 1:39 PM
Transplantation of human iPSC-derived retinal cells in the cone-dominant Northern tree shrew https://www.biorxiv.org/content/10.64898/2026.10.28.761748v1
November 3, 2026 at 12:16 PM
Transplantation of human iPSC-derived retinal cells in the cone-dominant Northern tree shrew https://www.biorxiv.org/content/10.64898/2026.10.28.761748v1
Transplantation of human iPSC-derived retinal cells in the cone-dominant Northern tree shrew https://www.biorxiv.org/content/10.64898/2026.10.28.761748v1
November 3, 2026 at 12:16 PM
Transplantation of human iPSC-derived retinal cells in the cone-dominant Northern tree shrew https://www.biorxiv.org/content/10.64898/2026.10.28.761748v1
Gentamicin impairs nephron development in iPSC-derived kidney organoids and disrupts proximal tubular lysosomal function https://www.biorxiv.org/content/10.64898/2026.10.28.762495v1
November 3, 2026 at 6:01 PM
Gentamicin impairs nephron development in iPSC-derived kidney organoids and disrupts proximal tubular lysosomal function https://www.biorxiv.org/content/10.64898/2026.10.28.762495v1
An Isogenic iPSC Model of LMNA p.R482W Recapitulates Adipocyte Dysfunction in Familial Partial Lipodystrophy Type 2 https://www.biorxiv.org/content/10.64898/2026.10.29.760154v1
November 2, 2026 at 6:33 PM
An Isogenic iPSC Model of LMNA p.R482W Recapitulates Adipocyte Dysfunction in Familial Partial Lipodystrophy Type 2 https://www.biorxiv.org/content/10.64898/2026.10.29.760154v1
🧪NEW DATA - Qkine Y-27632 dihydrochloride (Qk1104) validated for improved viability in iPSC during thawing and plating.
View and buy Y-27632 (Qk1104) > zurl.co/ukwk8
#stemcells #animalfree
View and buy Y-27632 (Qk1104) > zurl.co/ukwk8
#stemcells #animalfree
November 4, 2026 at 8:39 AM
🧪NEW DATA - Qkine Y-27632 dihydrochloride (Qk1104) validated for improved viability in iPSC during thawing and plating.
View and buy Y-27632 (Qk1104) > zurl.co/ukwk8
#stemcells #animalfree
View and buy Y-27632 (Qk1104) > zurl.co/ukwk8
#stemcells #animalfree
Why don’t all lab-grown brain models develop the same way? Daniel Geschwind & colleagues examined 85 human stem cell lines used to study inherited dementia & found even seemingly similar stem cells can have important differences that affect how well they grow into brain-like models: t.co/8FdPl7e0AL
November 4, 2026 at 6:49 PM
Why don’t all lab-grown brain models develop the same way? Daniel Geschwind & colleagues examined 85 human stem cell lines used to study inherited dementia & found even seemingly similar stem cells can have important differences that affect how well they grow into brain-like models: t.co/8FdPl7e0AL
Phenotypic screening in Parkinson's iPSC-dopamine neurons identifies the FASN-SREBP1 axis as a potential therapeutic target #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.64898/2026.10.27.761977v1
https://www.biorxiv.org/content/10.64898/2026.10.27.761977v1
November 1, 2026 at 11:01 PM
Phenotypic screening in Parkinson's iPSC-dopamine neurons identifies the FASN-SREBP1 axis as a potential therapeutic target #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.64898/2026.10.27.761977v1
https://www.biorxiv.org/content/10.64898/2026.10.27.761977v1
Current treatments for ALS remains limited. This review examines MSC, NSC and iPSC therapies, examining stem cell therapies which could slow motor function loss and reduce symptom severity 🧠📋 #ALS #RegenerativeMedicine
mdpi.com/2227-9059/13...
mdpi.com/2227-9059/13...
November 5, 2026 at 6:20 AM
Current treatments for ALS remains limited. This review examines MSC, NSC and iPSC therapies, examining stem cell therapies which could slow motor function loss and reduce symptom severity 🧠📋 #ALS #RegenerativeMedicine
mdpi.com/2227-9059/13...
mdpi.com/2227-9059/13...
Couldn't wait for morning: #FluorescenceFriday images fresh off the 🔬 posted on a project channel 🤩🤩 - I am so frigging excited about this project - human iPSC-derived locus coeruleus like neurons in culture 🟢 TH, 🟡 PHOX2B and 🟣 MAP2. Image credit to Haya AlGrain and the Imaging Development team 👩🔬🧪
October 29, 2026 at 11:52 PM
Couldn't wait for morning: #FluorescenceFriday images fresh off the 🔬 posted on a project channel 🤩🤩 - I am so frigging excited about this project - human iPSC-derived locus coeruleus like neurons in culture 🟢 TH, 🟡 PHOX2B and 🟣 MAP2. Image credit to Haya AlGrain and the Imaging Development team 👩🔬🧪
Phenotypic screening in Parkinson's iPSC-dopamine neurons identifies the FASN-SREBP1 axis as a potential therapeutic target https://www.biorxiv.org/content/10.64898/2026.10.27.761977v1
November 1, 2026 at 8:15 PM
Phenotypic screening in Parkinson's iPSC-dopamine neurons identifies the FASN-SREBP1 axis as a potential therapeutic target https://www.biorxiv.org/content/10.64898/2026.10.27.761977v1
Phenotypic screening in Parkinson's iPSC-dopamine neurons identifies the FASN-SREBP1 axis as a potential therapeutic target https://www.biorxiv.org/content/10.64898/2026.10.27.761977v1
November 1, 2026 at 8:15 PM
Phenotypic screening in Parkinson's iPSC-dopamine neurons identifies the FASN-SREBP1 axis as a potential therapeutic target https://www.biorxiv.org/content/10.64898/2026.10.27.761977v1
🎓 Free CE credits available! Learn how to build scalable, reproducible 3D & organoid models for NAMs and CIVMs, including iPSC-derived neural, lung & cardiac organoids.
📅 Nov 5 | 10 AM PT / 1 PM ET
👉 Register:
buff.ly/vJWYcdw
📅 Nov 5 | 10 AM PT / 1 PM ET
👉 Register:
buff.ly/vJWYcdw
November 4, 2026 at 5:07 PM
🎓 Free CE credits available! Learn how to build scalable, reproducible 3D & organoid models for NAMs and CIVMs, including iPSC-derived neural, lung & cardiac organoids.
📅 Nov 5 | 10 AM PT / 1 PM ET
👉 Register:
buff.ly/vJWYcdw
📅 Nov 5 | 10 AM PT / 1 PM ET
👉 Register:
buff.ly/vJWYcdw
🧬 Funded PhD: Editing the Alzheimer's Epigenome at the University of Exeter
Use CRISPR epigenome editing and iPSC-derived microglia to find which Alzheimer's-linked epigenetic changes actually drive disease.
⏰ Closes 5 Jan 2027
www.dementiaresearcher.nihr.ac.uk/job/phd-edit...
Use CRISPR epigenome editing and iPSC-derived microglia to find which Alzheimer's-linked epigenetic changes actually drive disease.
⏰ Closes 5 Jan 2027
www.dementiaresearcher.nihr.ac.uk/job/phd-edit...
PhD: Editing the Alzheimer’s Epigenome - Dementia Researcher
Funded MRC PhD at the University of Exeter using CRISPR epigenome editing and iPSC microglia to test which Alzheimer's epigenetic changes matter.
www.dementiaresearcher.nihr.ac.uk
October 30, 2026 at 4:54 PM
🧬 Funded PhD: Editing the Alzheimer's Epigenome at the University of Exeter
Use CRISPR epigenome editing and iPSC-derived microglia to find which Alzheimer's-linked epigenetic changes actually drive disease.
⏰ Closes 5 Jan 2027
www.dementiaresearcher.nihr.ac.uk/job/phd-edit...
Use CRISPR epigenome editing and iPSC-derived microglia to find which Alzheimer's-linked epigenetic changes actually drive disease.
⏰ Closes 5 Jan 2027
www.dementiaresearcher.nihr.ac.uk/job/phd-edit...
I mean, I’m on a first name basis with rather a lot of USPSA/IPSC GMs, as well as higher-end shooters in the tacticool world.
Bubba Magagoon on GunDorkForums has no idea what ”a lot of shooting“ is. I’ve shot over a case of ammo in a weekend class numerous times.
Bubba Magagoon on GunDorkForums has no idea what ”a lot of shooting“ is. I’ve shot over a case of ammo in a weekend class numerous times.
October 30, 2026 at 5:01 PM
I mean, I’m on a first name basis with rather a lot of USPSA/IPSC GMs, as well as higher-end shooters in the tacticool world.
Bubba Magagoon on GunDorkForums has no idea what ”a lot of shooting“ is. I’ve shot over a case of ammo in a weekend class numerous times.
Bubba Magagoon on GunDorkForums has no idea what ”a lot of shooting“ is. I’ve shot over a case of ammo in a weekend class numerous times.
Stem-cell therapy is moving T1D toward a real cure—regenerating β-cells instead of lifelong insulin. Promising early results (VX-880, iPSC islets), but safety, cost & pediatric data still lag.
link.springer.com/article/10.1...
#StemCellTherapy #Type1Diabetes
link.springer.com/article/10.1...
#StemCellTherapy #Type1Diabetes
October 30, 2026 at 9:09 AM
Stem-cell therapy is moving T1D toward a real cure—regenerating β-cells instead of lifelong insulin. Promising early results (VX-880, iPSC islets), but safety, cost & pediatric data still lag.
link.springer.com/article/10.1...
#StemCellTherapy #Type1Diabetes
link.springer.com/article/10.1...
#StemCellTherapy #Type1Diabetes