what bluesky needs is an internalization of this
January 20, 2025 at 12:50 AM
what bluesky needs is an internalization of this
I really want to write an article about how unfocused consumer boycotts like this are the ultimate internalization of neoliberal politics, how it's this naive view that your individual consumer preferences are somehow transformed into progressive activism
Okay seriously. Why. For what reason. What is a super bowl blackout supposed to do.
February 9, 2025 at 4:45 PM
I really want to write an article about how unfocused consumer boycotts like this are the ultimate internalization of neoliberal politics, how it's this naive view that your individual consumer preferences are somehow transformed into progressive activism
Doomerism is the ultimate triumph of the Trump worldview: the internalization by Democrats that a victory of the fascist order is a prima facie conclusion. If we can’t learn to overcome it, we’ve beaten ourselves.
October 26, 2024 at 5:31 PM
Doomerism is the ultimate triumph of the Trump worldview: the internalization by Democrats that a victory of the fascist order is a prima facie conclusion. If we can’t learn to overcome it, we’ve beaten ourselves.
“Under the condition of social media, pauperization, the internalization of unsatisfiable wants and needs becomes universal. We can all constantly see what we don’t have.”
Mob Rule
On Social Media and the Universal Experience of Poverty
open.substack.com
January 16, 2025 at 9:50 PM
“Under the condition of social media, pauperization, the internalization of unsatisfiable wants and needs becomes universal. We can all constantly see what we don’t have.”
It would be nice if we could reckon with the internalization of anti-transition rhetoric in trans spaces without going full "I have a doctor's letter for my gender" about it
I think the backlash to "you don't have to transition uwu" politics is making some ppl come out of the woodwork as to what exactly they find ew gross and funny and shame-worthy
September 12, 2026 at 7:32 PM
It would be nice if we could reckon with the internalization of anti-transition rhetoric in trans spaces without going full "I have a doctor's letter for my gender" about it
The full internalization of "better things aren't possible" is "well then let me decide who I want worse things for"
April 14, 2025 at 9:52 PM
The full internalization of "better things aren't possible" is "well then let me decide who I want worse things for"
A Congress that’s knows how bad the bill is for their constituents, but going to do it anyway, because they have been primed for months with “daddy’s home” garbage internalization.
Enten: "You don't have to be a mathematical genius to know that these are horrible, horrible, horrible numbers. Washington Post, -19 points, Fox News -21 points...to quote Sir Charles Barkley, 'terrible terrible terrible'...it's one of the most unpopular pieces of legislation that I have ever seen"
June 30, 2025 at 10:50 PM
A Congress that’s knows how bad the bill is for their constituents, but going to do it anyway, because they have been primed for months with “daddy’s home” garbage internalization.
I blame my parents for this internalization
February 13, 2025 at 12:28 PM
I blame my parents for this internalization
the funniest debuff in all of gaming still has to go to art cop internalization
August 22, 2025 at 7:29 PM
the funniest debuff in all of gaming still has to go to art cop internalization
BTS by their reaction to reading thirst posts about them:
JK: Bemused acceptance
SJ: Vocal outrage
YG: Smug satisfaction
NJ: Embarrassed appreciation
HS: Academic internalization
JM: Coy denial
TH: Competitive fervor
JK: Bemused acceptance
SJ: Vocal outrage
YG: Smug satisfaction
NJ: Embarrassed appreciation
HS: Academic internalization
JM: Coy denial
TH: Competitive fervor
May 20, 2025 at 2:59 PM
BTS by their reaction to reading thirst posts about them:
JK: Bemused acceptance
SJ: Vocal outrage
YG: Smug satisfaction
NJ: Embarrassed appreciation
HS: Academic internalization
JM: Coy denial
TH: Competitive fervor
JK: Bemused acceptance
SJ: Vocal outrage
YG: Smug satisfaction
NJ: Embarrassed appreciation
HS: Academic internalization
JM: Coy denial
TH: Competitive fervor
Anyways, I think there needs to be a serious internalization of “trans women are women.” I think there is a deep lack of understanding of how transmisogyny is in fact misogyny. Trans women are marginalized women. The dual harmful societal fixation/erasure is the marginalized woman’s struggle.
April 9, 2026 at 3:12 PM
Anyways, I think there needs to be a serious internalization of “trans women are women.” I think there is a deep lack of understanding of how transmisogyny is in fact misogyny. Trans women are marginalized women. The dual harmful societal fixation/erasure is the marginalized woman’s struggle.
The only thing harder to talk about than deception in RPGs is internalization of GM antipathy.
May 10, 2026 at 2:10 PM
The only thing harder to talk about than deception in RPGs is internalization of GM antipathy.
June 10, 2025 at 1:06 PM
Forcing the internalization of externalized costs is Woke 2.
We should just directly tax the weight of a vehicle, especially in cities.
There is no fucking reason for everybody, their two daughters and their dog to each own an F150.
We should levy the cost of road maintenance and traffic calming and pedestrian nation upon those who make it all so difficult.
There is no fucking reason for everybody, their two daughters and their dog to each own an F150.
We should levy the cost of road maintenance and traffic calming and pedestrian nation upon those who make it all so difficult.
the fact that early-stage automated vehicles that still occasionally require remote operation assistance are like several orders of magnitude safer than the average American driver should be the real wakeup call here, not the idea that these vehicles still sometimes need remote operation assistance
February 6, 2026 at 7:59 PM
Forcing the internalization of externalized costs is Woke 2.
Internalization
Looking back…
#internalization, #smArtist, #mono, #photographersOfBlueSky,
#EastCoastKin, #artChallenges
#dogPhotography
Looking back…
#internalization, #smArtist, #mono, #photographersOfBlueSky,
#EastCoastKin, #artChallenges
#dogPhotography
June 10, 2025 at 2:44 PM
Internalization
Looking back…
#internalization, #smArtist, #mono, #photographersOfBlueSky,
#EastCoastKin, #artChallenges
#dogPhotography
Looking back…
#internalization, #smArtist, #mono, #photographersOfBlueSky,
#EastCoastKin, #artChallenges
#dogPhotography
I was transsexual from my earliest memories. My young child internalization of the concept of gender, and gender relations, was all filtered through my implicit transsexuality.
June 21, 2025 at 4:54 PM
I was transsexual from my earliest memories. My young child internalization of the concept of gender, and gender relations, was all filtered through my implicit transsexuality.
I got diagnosed at 52 and one of the hardest things is undoing a bunch of that internalization. I’m still very far from accomplishing that.
May 5, 2025 at 10:39 PM
I got diagnosed at 52 and one of the hardest things is undoing a bunch of that internalization. I’m still very far from accomplishing that.
Previous preprint is now published in RSC Chemical Biology.
If you are interested in plasma membrane labeling, see the paper! 👇
pubs.rsc.org/en/content/a...
If you are interested in plasma membrane labeling, see the paper! 👇
pubs.rsc.org/en/content/a...
September 8, 2025 at 8:02 AM
Previous preprint is now published in RSC Chemical Biology.
If you are interested in plasma membrane labeling, see the paper! 👇
pubs.rsc.org/en/content/a...
If you are interested in plasma membrane labeling, see the paper! 👇
pubs.rsc.org/en/content/a...
Stop for a second and try to imagine this: a heat shock protein relocalizes to the cell surface and mediates dsRNA binding and internalization!
Intrigued? Read our newly minted paper in Science Advances www.science.org/doi/10.1126/...
Congrats to all the authors and thanks to reviewers and editor!
Intrigued? Read our newly minted paper in Science Advances www.science.org/doi/10.1126/...
Congrats to all the authors and thanks to reviewers and editor!
Hsc70-4: An unanticipated mediator of dsRNA internalization in Drosophila
Hsc70-4 localizes to the cell surface of Drosophila cells, binds to exogenous dsRNA, and mediates its internalization.
www.science.org
May 20, 2025 at 2:47 PM
Stop for a second and try to imagine this: a heat shock protein relocalizes to the cell surface and mediates dsRNA binding and internalization!
Intrigued? Read our newly minted paper in Science Advances www.science.org/doi/10.1126/...
Congrats to all the authors and thanks to reviewers and editor!
Intrigued? Read our newly minted paper in Science Advances www.science.org/doi/10.1126/...
Congrats to all the authors and thanks to reviewers and editor!
NEW #Oncology:
EGFR expression mediates resistance to T-DXd (EGFR overexpression ⬇️ HER2 homodimerization & HER2/ADC internalization)
Combining with EGFR mAbs restored HER2/ADC trafficking & ⬆️ activity in nonclinical models
#DrugDevelopment #OncoSky
www.cell.com/cell-reports...
EGFR expression mediates resistance to T-DXd (EGFR overexpression ⬇️ HER2 homodimerization & HER2/ADC internalization)
Combining with EGFR mAbs restored HER2/ADC trafficking & ⬆️ activity in nonclinical models
#DrugDevelopment #OncoSky
www.cell.com/cell-reports...
EGFR-directed antibodies promote HER2 ADC internalization and efficacy
Gupta et al. demonstrate that high EGFR expression mediates resistance to HER2 antibody
drug conjugates (ADCs) including trastuzumab deruxtecan (T-DXd) by limiting HER2/ADC
internalization. The additi...
www.cell.com
November 12, 2024 at 12:33 PM
NEW #Oncology:
EGFR expression mediates resistance to T-DXd (EGFR overexpression ⬇️ HER2 homodimerization & HER2/ADC internalization)
Combining with EGFR mAbs restored HER2/ADC trafficking & ⬆️ activity in nonclinical models
#DrugDevelopment #OncoSky
www.cell.com/cell-reports...
EGFR expression mediates resistance to T-DXd (EGFR overexpression ⬇️ HER2 homodimerization & HER2/ADC internalization)
Combining with EGFR mAbs restored HER2/ADC trafficking & ⬆️ activity in nonclinical models
#DrugDevelopment #OncoSky
www.cell.com/cell-reports...
Many people are fooled by this feeling. Watching YouTube videos, reading the answer key, asking an LLM. They all shortcut internalization
June 8, 2026 at 2:16 PM
Many people are fooled by this feeling. Watching YouTube videos, reading the answer key, asking an LLM. They all shortcut internalization
I have put the internalization into a format you can understand
April 7, 2026 at 9:33 PM
I have put the internalization into a format you can understand
But this is also the problem with the internalization of the eternal victim narrative, sigh
June 25, 2025 at 7:31 PM
But this is also the problem with the internalization of the eternal victim narrative, sigh
Figured out the favorite foods internalization
April 11, 2026 at 12:43 AM
Figured out the favorite foods internalization
I am good friends with a Professor of English literature at Oxford University who agrees wholeheartedly with you. He is particularly keen on the internalization of the audience through Gonzo - apparently a key Dickensian device.
December 26, 2025 at 8:14 AM
I am good friends with a Professor of English literature at Oxford University who agrees wholeheartedly with you. He is particularly keen on the internalization of the audience through Gonzo - apparently a key Dickensian device.