#keratoderma
Signs I have become desensitized to weird foot stuff: looking at pictures of plantar keratoderma while eating my breakfast
May 8, 2025 at 7:15 AM
Naxos Disease is a rare autosomal recessive condition characterized by the triad of arrhythmogenic cardiomyopathy, woolly hair, and palmoplantar keratoderma.

Learn more: https://dub.sh/Naxos

You may be rare, but you're not alone!
#rareDisease #rareDiseaseAwareness
March 5, 2026 at 3:00 PM
🚀 In this study, @gjbarton.bsky.social and I collaborated with the group of Gopal #Sapkota at the @mrcppu.bsky.social at the #SLS of the University of Dundee to shed some light into the loss of interaction between #SACK1G and #CK1α, which underlies the pathogenesis of Palmoplantar Keratoderma (PPK).
January 9, 2026 at 10:40 AM
I’ve often said that keratoderma blennorrhagica is clinically indistinguishable from pustular psoriasis, at least to the untrained eye.
February 27, 2025 at 2:42 AM
2025 Wk2 M60s. 5y h/o 2-3mm keratotic endophytic papules palms & soles. ?Viral warts ?Keratoderma ?Other #Dermpath 😇 Hope gets more response c/w X
January 12, 2025 at 11:51 AM
REACTIVE ARTHRITIS can occur following infection with Chlamydia, Campylobacter, Salmonella, Shigella, or Yersinia.

-HLA-B27(+)
-Sterile arthritis (due to deposition of immune complexes)
-Conjunctivitis
-Urethritis
-Enthesitis, dactylitis
-Keratoderma blennorrhagicum
-Oral ulcers
February 17, 2025 at 10:25 PM
You're close, very close! Punctate palmoplantar keratoderma, type 1. Clinical v important. Keratotic papules can drop out leaving pits (this was reported as "cyst") but we can see the hyperkeratosis here too. Clinicians wanted histo review.
January 23, 2025 at 6:11 PM
🚀 For this study, @gjbarton.bsky.social and I teamed up with the group of Gopal #Sapkota at @mrcppu.bsky.social in the School of Life Sciences of Dundee Uni to shed some light in the loss of interaction between #SACK1G and #CK1α, which underlies the pathogenesis of #Palmoplantar #Keratoderma (PPK).
July 1, 2025 at 1:53 PM
Activating #EGFR variants were identified in early-onset, severe generalized #AcanthosisNigricans with pulmonary nodules; EGFR inhibitor therapy improved both skin and lung disease. ja.ma/4bw0Rnp
January 15, 2026 at 3:00 PM
🔬 SERPINA12 gene joins the growing list of genes linked to palmoplantar keratoderma, offering new diagnostic possibilities for patients with unexplained skin thickening.

https://news.gmj.ge/?p=16605
Key Finding: SERPINA12 Gene Mutations Identified as New Cause of Hereditary Palmoplantar Keratoderma
🔬 SERPINA12 gene joins the growing list of genes linked to palmoplantar keratoderma, offering new diagnostic possibilities for patients with unexplained skin thickening.
news.gmj.ge
September 14, 2026 at 2:10 PM
3 key points about SERPINA12 discovery: 1️⃣ New genetic cause of palmoplantar keratoderma identified 2️⃣ Expands genetic testing panel for rare skin disorders 3️⃣ May…

https://news.gmj.ge/?p=16606
Takeaway: SERPINA12 Gene Mutations Identified as New Cause of Hereditary Palmoplantar Keratoderma
3 key points about SERPINA12 discovery: 1️⃣ New genetic cause of palmoplantar keratoderma identified 2️⃣ Expands genetic testing panel for rare skin disorders 3️⃣ May…
news.gmj.ge
September 14, 2026 at 2:25 PM
🧬 Breakthrough discovery: SERPINA12 gene mutations identified as new cause of hereditary palmoplantar keratoderma, a rare skin disorder affecting palms and soles. This finding expands…

https://news.gmj.ge/?p=16604
Announcement: SERPINA12 Gene Mutations Identified as New Cause of Hereditary Palmoplantar Keratoderma
🧬 Breakthrough discovery: SERPINA12 gene mutations identified as new cause of hereditary palmoplantar keratoderma, a rare skin disorder affecting palms and soles. This finding expands…
news.gmj.ge
September 14, 2026 at 2:05 PM
This is a finding known a keratoderma blennorrhagicum. It points to reactive arthritis, but it is grossly and histologically indistinguishable from pustular psoriasis; clinical context is absolutely needed for the diagnosis.
#meded
July 17, 2026 at 3:30 PM
Scientists studied a group of patients with palmoplantar keratoderma, a skin condition that affects hands and feet, and found many genetic causes. Genetic testing helped improve their understanding of the condition, offering clearer diagnoses. This research will guide future studies on the disorder.
Clinical and Genetic Findings in Patients With Palmoplantar Keratoderma.
Published in JAMA dermatology
doi.org
December 4, 2024 at 8:00 PM
Palmoplantar Keratoderma Clinical Trials, Companies, Therapeutic Assessment, Therapies, Treatment Algorithm, Pipeline Analysis | Sol-Gel Technologies Ltd., Krystal Biotech Inc.
www.pressreleasecc.com
November 8, 2025 at 12:12 PM
Feed: "Medical Xpress - latest medical and health news stories"
Published on Thursday, January 22, 2026
Researchers establish the cause of keratoderma-associated foot odor
The distinct foot odor that comes with the skin disorder Nagashima-type palmoplantar keratosis (NPPK) is caused by the overgrowth of a specific bacterial strain, according to a study published in the ...
medicalxpress.com
January 23, 2026 at 3:25 PM
Causes of cracked heels:

Prolonged standing
Wearing open-back shoes
Wearing shoes that don’t cushion the heels
Living in a cold or dry climate
Taking long, hot showers
Not moisturising the heels
Eczema
Psoriasis
Palmoplantar keratoderma
Juvenile plantar dermatosis
November 27, 2025 at 8:50 PM
Causes of cracked heels include:

Prolonged standing
Wearing open-back shoes
Wearing shoes that don’t cushion the heels
Living in a cold or dry climate
Taking long, hot showers
Not moisturising the heels
Eczema
Psoriasis
Palmoplantar keratoderma
Juvenile plantar dermatosis

#footcare #crackedheels
October 29, 2025 at 3:10 PM
Activating #EGFR variants were identified in early-onset, severe generalized #AcanthosisNigricans with pulmonary nodules; EGFR inhibitor therapy improved both skin and lung disease. ja.ma/4rKi9CP
March 21, 2026 at 1:00 PM
The EBSdart scoring tool reliably measures disease severity in epidermolysis bullosa simplex across age groups, showing strong interrater agreement and generalizability, and may aid future clinical trials and therapy development.

ja.ma/49j9KhF
January 2, 2026 at 2:00 PM
The EBSdart scoring tool reliably measures disease severity in epidermolysis bullosa simplex across age groups, showing strong interrater agreement and generalizability, and may aid future clinical trials and therapy development. ja.ma/44OsEvg
December 31, 2025 at 1:00 PM