Late thanks to the Lorne Proteins OC! You did it again-inspiring speakers, excellent ECR talks, impressive student posters, nice vibes and icecream mixers 🍦 Thanks to our generous sponsors and awesome attendees for making this an unmissable event!
See you next year 🏖️ 🏄 🤓
#LorneProteins2026
See you next year 🏖️ 🏄 🤓
#LorneProteins2026
March 10, 2026 at 7:22 AM
Late thanks to the Lorne Proteins OC! You did it again-inspiring speakers, excellent ECR talks, impressive student posters, nice vibes and icecream mixers 🍦 Thanks to our generous sponsors and awesome attendees for making this an unmissable event!
See you next year 🏖️ 🏄 🤓
#LorneProteins2026
See you next year 🏖️ 🏄 🤓
#LorneProteins2026
What a week it's been at the 2026 Lorne Proteins Conference! Centre Director Trevor Lithgow & members of his lab from Monash University attended - showing off their work and taking in the latest research that this important conference showcases. @lorneproteins.bsky.social #lorneproteins2026
February 12, 2026 at 3:21 AM
What a week it's been at the 2026 Lorne Proteins Conference! Centre Director Trevor Lithgow & members of his lab from Monash University attended - showing off their work and taking in the latest research that this important conference showcases. @lorneproteins.bsky.social #lorneproteins2026
February 11, 2026 at 7:22 AM
See list of previous Leach Lecture awardees of #LorneProteins at www.lorneproteins.org/past-leach-l... #lorneproteins2026
Past Leach Lectures — Lorne Proteins 2026
www.lorneproteins.org
February 11, 2026 at 3:18 AM
See list of previous Leach Lecture awardees of #LorneProteins at www.lorneproteins.org/past-leach-l... #lorneproteins2026
Closing Session 10: Jeanine Amacher | Amino acid variants at the P94 position in S. aureus class A sortase modulate substrate access and activity
Position specific regulation of activity.
Cat cys recognises short LPXTG
Sortase-catalysed ligation
Any acyl support!
#sortase
#lorneproteins2026
Position specific regulation of activity.
Cat cys recognises short LPXTG
Sortase-catalysed ligation
Any acyl support!
#sortase
#lorneproteins2026
February 11, 2026 at 1:28 AM
Closing Session 10: Jeanine Amacher | Amino acid variants at the P94 position in S. aureus class A sortase modulate substrate access and activity
Position specific regulation of activity.
Cat cys recognises short LPXTG
Sortase-catalysed ligation
Any acyl support!
#sortase
#lorneproteins2026
Position specific regulation of activity.
Cat cys recognises short LPXTG
Sortase-catalysed ligation
Any acyl support!
#sortase
#lorneproteins2026
Session 10 - Liyu Chen | JAM-1 nanobody induces barrier weakening and enhanced drug permeability in an in vitro blood-brain barrier-like model
Strategies for cerebral drug delivery.
#lorneproteins2026
Strategies for cerebral drug delivery.
#lorneproteins2026
February 11, 2026 at 1:06 AM
Session 10 - Liyu Chen | JAM-1 nanobody induces barrier weakening and enhanced drug permeability in an in vitro blood-brain barrier-like model
Strategies for cerebral drug delivery.
#lorneproteins2026
Strategies for cerebral drug delivery.
#lorneproteins2026
Session 10: Rina Rosenzweig on molecular chaperones, J-domain proteins
Most diverse family - 50 different members
#lorneproteins2026
Most diverse family - 50 different members
#lorneproteins2026
February 11, 2026 at 12:10 AM
Session 10: Rina Rosenzweig on molecular chaperones, J-domain proteins
Most diverse family - 50 different members
#lorneproteins2026
Most diverse family - 50 different members
#lorneproteins2026
Closing Session 9:
Tzviya Zeev-Ben-Mordehai on cryoET of the cellular structural biology of mammalian sperm
#lorneproteins2026
Tzviya Zeev-Ben-Mordehai on cryoET of the cellular structural biology of mammalian sperm
#lorneproteins2026
February 10, 2026 at 11:02 PM
Closing Session 9:
Tzviya Zeev-Ben-Mordehai on cryoET of the cellular structural biology of mammalian sperm
#lorneproteins2026
Tzviya Zeev-Ben-Mordehai on cryoET of the cellular structural biology of mammalian sperm
#lorneproteins2026
Session 9: Yu Shang Low - RHS proteins possess YD repeat cages that underlies their functional diversity
#lorneproteins2026
#lorneproteins2026
February 10, 2026 at 10:37 PM
Session 9: Yu Shang Low - RHS proteins possess YD repeat cages that underlies their functional diversity
#lorneproteins2026
#lorneproteins2026
Session 9: Kai-En Chen: Structural basis of the membrane-assembled Retromer – Rab7 complex: A molecular timer for vacuolar cargo retrieval
#lorneproteins2026
#lorneproteins2026
February 10, 2026 at 10:19 PM
Session 9: Kai-En Chen: Structural basis of the membrane-assembled Retromer – Rab7 complex: A molecular timer for vacuolar cargo retrieval
#lorneproteins2026
#lorneproteins2026
Be part of Lorne Proteins history! Photo session today from 1-1:10 pm. See you there 🎉📷🤩
#lorneproteins2026
#lorneproteins2026
Lovely photo taken at the 50th @lorneproteins.bsky.social conference last week. Gathering included some of the greats from the very first #proteins meeting held at Lorne.
February 10, 2026 at 10:17 PM
Be part of Lorne Proteins history! Photo session today from 1-1:10 pm. See you there 🎉📷🤩
#lorneproteins2026
#lorneproteins2026
Recapture of the replication gene variants with crispr/cas. Yield of replicating phage as a measure of the efficiency of a deep mutational library of the clamp loader.
Bare minimum background by swapping in a different clamp loader reducing fitness >1000 fold.
#lorneproteins2026
Bare minimum background by swapping in a different clamp loader reducing fitness >1000 fold.
#lorneproteins2026
February 10, 2026 at 9:08 AM
Recapture of the replication gene variants with crispr/cas. Yield of replicating phage as a measure of the efficiency of a deep mutational library of the clamp loader.
Bare minimum background by swapping in a different clamp loader reducing fitness >1000 fold.
#lorneproteins2026
Bare minimum background by swapping in a different clamp loader reducing fitness >1000 fold.
#lorneproteins2026
#lorneproteins2026 resident troublemakers taking a break with a burger on a banksia.
Or AI Haiku
Galah steals a bite,
Banksia perch in Lorne bay,
Fast food, feathered friend.
Or AI Haiku
Galah steals a bite,
Banksia perch in Lorne bay,
Fast food, feathered friend.
February 10, 2026 at 3:53 AM
#lorneproteins2026 resident troublemakers taking a break with a burger on a banksia.
Or AI Haiku
Galah steals a bite,
Banksia perch in Lorne bay,
Fast food, feathered friend.
Or AI Haiku
Galah steals a bite,
Banksia perch in Lorne bay,
Fast food, feathered friend.
@ansto.bsky.social thanks for supporting the lightning talks session 7 at #lorneproteins2026
An invigorating pace and excellent variety of subjects! Great session 🤩
An invigorating pace and excellent variety of subjects! Great session 🤩
February 10, 2026 at 2:27 AM
@ansto.bsky.social thanks for supporting the lightning talks session 7 at #lorneproteins2026
An invigorating pace and excellent variety of subjects! Great session 🤩
An invigorating pace and excellent variety of subjects! Great session 🤩
February 10, 2026 at 1:56 AM
S7 ⚡️⚡️⚡️⚡️⚡️⚡️⚡️ Adnan Sljoka Probing allostery with computational techniques e.g. GPCRs - NMR, Monte carlo simulations, conf dynamics, how allostery regulates dynamics.
Dont forget buried waters!!
ms timescales of motion... textbook - rigidity theory:
Sublinear computation paradigm
#lorneproteins2026
Dont forget buried waters!!
ms timescales of motion... textbook - rigidity theory:
Sublinear computation paradigm
#lorneproteins2026
February 10, 2026 at 1:31 AM
S7 ⚡️⚡️⚡️⚡️⚡️⚡️⚡️ Adnan Sljoka Probing allostery with computational techniques e.g. GPCRs - NMR, Monte carlo simulations, conf dynamics, how allostery regulates dynamics.
Dont forget buried waters!!
ms timescales of motion... textbook - rigidity theory:
Sublinear computation paradigm
#lorneproteins2026
Dont forget buried waters!!
ms timescales of motion... textbook - rigidity theory:
Sublinear computation paradigm
#lorneproteins2026
S7 ⚡️⚡️⚡️⚡️⚡️ Hari Venugopal - heavy load Arctica for screening. Can we screen with a lab6 for structure?
Biggest problem is drift. Lend me a half mill GATAN Alpine direct electron detector? Yes!
ApoF 170 images/hr <3 Å Dose 60. GPCR 1000 images, 50k particles, 4.5 Å structure.
#lorneproteins2026
Biggest problem is drift. Lend me a half mill GATAN Alpine direct electron detector? Yes!
ApoF 170 images/hr <3 Å Dose 60. GPCR 1000 images, 50k particles, 4.5 Å structure.
#lorneproteins2026
February 10, 2026 at 1:11 AM
S7 ⚡️⚡️⚡️⚡️⚡️ Hari Venugopal - heavy load Arctica for screening. Can we screen with a lab6 for structure?
Biggest problem is drift. Lend me a half mill GATAN Alpine direct electron detector? Yes!
ApoF 170 images/hr <3 Å Dose 60. GPCR 1000 images, 50k particles, 4.5 Å structure.
#lorneproteins2026
Biggest problem is drift. Lend me a half mill GATAN Alpine direct electron detector? Yes!
ApoF 170 images/hr <3 Å Dose 60. GPCR 1000 images, 50k particles, 4.5 Å structure.
#lorneproteins2026
February 10, 2026 at 12:56 AM
S7 ⚡️⚡️⚡️ Neil Robertson - Rational design of a protein motor. A minimal, simple walker. Ligand gated, 3 'feet', tumbleweed on a track. Ligand dependent DBDs in a trimer linked by spycatcher.
Speed limit from spr release affinities. 2-3 s.
Processivity: how long it stays attached
#lorneproteins2026
Speed limit from spr release affinities. 2-3 s.
Processivity: how long it stays attached
#lorneproteins2026
February 10, 2026 at 12:43 AM
S7 ⚡️⚡️⚡️ Neil Robertson - Rational design of a protein motor. A minimal, simple walker. Ligand gated, 3 'feet', tumbleweed on a track. Ligand dependent DBDs in a trimer linked by spycatcher.
Speed limit from spr release affinities. 2-3 s.
Processivity: how long it stays attached
#lorneproteins2026
Speed limit from spr release affinities. 2-3 s.
Processivity: how long it stays attached
#lorneproteins2026
S7 ⚡️⚡️ Sarah J Piper on GPCR PAC receptor subfamily. Cool animations #blender #molecularnodes #gunforhire
PAC1 variants have diverse signalling. Endog activators. VIP signalling on short PAC1?
H-bonding networks between peptide and receptors differ with potency.
+MD!
#lorneproteins2026
PAC1 variants have diverse signalling. Endog activators. VIP signalling on short PAC1?
H-bonding networks between peptide and receptors differ with potency.
+MD!
#lorneproteins2026
February 10, 2026 at 12:30 AM
S7 ⚡️⚡️ Sarah J Piper on GPCR PAC receptor subfamily. Cool animations #blender #molecularnodes #gunforhire
PAC1 variants have diverse signalling. Endog activators. VIP signalling on short PAC1?
H-bonding networks between peptide and receptors differ with potency.
+MD!
#lorneproteins2026
PAC1 variants have diverse signalling. Endog activators. VIP signalling on short PAC1?
H-bonding networks between peptide and receptors differ with potency.
+MD!
#lorneproteins2026
S7 ⚡️⚡️ Sarah J Piper on GPCR PAC receptor subfamily. Cool animations #blender #molecularnodes #gunforhire
PAC1 variants have diverse signalling. Endog activators. VIP signalling on short PAC1?
H-bonding networks between peptide and receptors differ with potency.
+MD!
#lorneproteins2026
PAC1 variants have diverse signalling. Endog activators. VIP signalling on short PAC1?
H-bonding networks between peptide and receptors differ with potency.
+MD!
#lorneproteins2026
February 10, 2026 at 12:27 AM
S7 ⚡️⚡️ Sarah J Piper on GPCR PAC receptor subfamily. Cool animations #blender #molecularnodes #gunforhire
PAC1 variants have diverse signalling. Endog activators. VIP signalling on short PAC1?
H-bonding networks between peptide and receptors differ with potency.
+MD!
#lorneproteins2026
PAC1 variants have diverse signalling. Endog activators. VIP signalling on short PAC1?
H-bonding networks between peptide and receptors differ with potency.
+MD!
#lorneproteins2026
Session 7 ⚡️🌩 talks time!! Jack Zeng Unravelling Promiscuity - OCT1 gating - structures of ligand bound states. Interrogating binding and transport specificity and mechanism.
#lorneproteins2026
#lorneproteins2026
February 10, 2026 at 12:13 AM
Session 7 ⚡️🌩 talks time!! Jack Zeng Unravelling Promiscuity - OCT1 gating - structures of ligand bound states. Interrogating binding and transport specificity and mechanism.
#lorneproteins2026
#lorneproteins2026
Closing Session 6: Simon Newstead - Animal to Atom: New avenues for targeting chronic pain.
Solute carrier signalling - signaling solute concentrations. Model 1 - e.g. No substrate, lumen ion conc changes. Transporter stabilises, permitting binding TASL, scaffolding its folding.
#lorneproteins2026
Solute carrier signalling - signaling solute concentrations. Model 1 - e.g. No substrate, lumen ion conc changes. Transporter stabilises, permitting binding TASL, scaffolding its folding.
#lorneproteins2026
February 9, 2026 at 11:08 PM
Closing Session 6: Simon Newstead - Animal to Atom: New avenues for targeting chronic pain.
Solute carrier signalling - signaling solute concentrations. Model 1 - e.g. No substrate, lumen ion conc changes. Transporter stabilises, permitting binding TASL, scaffolding its folding.
#lorneproteins2026
Solute carrier signalling - signaling solute concentrations. Model 1 - e.g. No substrate, lumen ion conc changes. Transporter stabilises, permitting binding TASL, scaffolding its folding.
#lorneproteins2026
S6: Renhong Yan - Heteromeric amino acid transporters.
Gating mechanism of LAT1-4F2hc complex. Apo, leu, tyr bound states.
y+LAT1-4F2hc - Leu import, export Arg; electroneutral 1:1
#lorneproteins2026
Gating mechanism of LAT1-4F2hc complex. Apo, leu, tyr bound states.
y+LAT1-4F2hc - Leu import, export Arg; electroneutral 1:1
#lorneproteins2026
February 9, 2026 at 10:46 PM
S6: Renhong Yan - Heteromeric amino acid transporters.
Gating mechanism of LAT1-4F2hc complex. Apo, leu, tyr bound states.
y+LAT1-4F2hc - Leu import, export Arg; electroneutral 1:1
#lorneproteins2026
Gating mechanism of LAT1-4F2hc complex. Apo, leu, tyr bound states.
y+LAT1-4F2hc - Leu import, export Arg; electroneutral 1:1
#lorneproteins2026
Session 6: Emily Furlong, Structural basis of Ni import by Type I ABC Transporters.
🤫
#lorneproteins2026
🤫
#lorneproteins2026
February 9, 2026 at 10:17 PM
Session 6: Emily Furlong, Structural basis of Ni import by Type I ABC Transporters.
🤫
#lorneproteins2026
🤫
#lorneproteins2026