Copy-back RNA synthesis by coronavirus polymerase requires helicase activity and is stimulated by remdesivir and molnupiravir | Science Advances www.science.org/doi/10.1126/...
#Coronavirus #SARS2 #COVID19 #singlemolecule #biophysics #magnetictweezers
#Coronavirus #SARS2 #COVID19 #singlemolecule #biophysics #magnetictweezers
Copy-back RNA synthesis by coronavirus polymerase requires helicase activity and is stimulated by remdesivir and molnupiravir
Helicase-driven copy-back RNA synthesis in coronaviruses reveals how antivirals trap replication intermediates.
www.science.org
June 20, 2026 at 9:05 AM
Copy-back RNA synthesis by coronavirus polymerase requires helicase activity and is stimulated by remdesivir and molnupiravir | Science Advances www.science.org/doi/10.1126/...
#Coronavirus #SARS2 #COVID19 #singlemolecule #biophysics #magnetictweezers
#Coronavirus #SARS2 #COVID19 #singlemolecule #biophysics #magnetictweezers
New preprint from the lab where we derived a simple and robust in situ force calibration method for high throughput #magnetictweezers that works even for short tethers and apply it to understand the mechanism of directional #mitochondrial #transcription termination by MTERF1.
Accurate single-bead force calibration in high-throughput magnetic tweezers reveals the mechanism of directional transcription termination by MTERF1 https://www.biorxiv.org/content/10.64898/2026.04.17.719150v1
April 21, 2026 at 8:37 PM
New preprint from the lab where we derived a simple and robust in situ force calibration method for high throughput #magnetictweezers that works even for short tethers and apply it to understand the mechanism of directional #mitochondrial #transcription termination by MTERF1.
🚀 Unlock the power of #Rheology anywhere with i-Rheo Web (Beta)!
🔹 i-Rheo – Stress relaxation analysis
🔹 i-Rheo GT – G(t) → G*(ω) transformation
🔹 i-Rheo FT – Generic functions
🔜 #AFM, #OpticalTweezers & #MagneticTweezers coming soon!
🌟 It’s time to embrace #Innovation! 😉
i-rheo.mib3avenger.com
🔹 i-Rheo – Stress relaxation analysis
🔹 i-Rheo GT – G(t) → G*(ω) transformation
🔹 i-Rheo FT – Generic functions
🔜 #AFM, #OpticalTweezers & #MagneticTweezers coming soon!
🌟 It’s time to embrace #Innovation! 😉
i-rheo.mib3avenger.com
May 5, 2025 at 10:48 AM
🚀 Unlock the power of #Rheology anywhere with i-Rheo Web (Beta)!
🔹 i-Rheo – Stress relaxation analysis
🔹 i-Rheo GT – G(t) → G*(ω) transformation
🔹 i-Rheo FT – Generic functions
🔜 #AFM, #OpticalTweezers & #MagneticTweezers coming soon!
🌟 It’s time to embrace #Innovation! 😉
i-rheo.mib3avenger.com
🔹 i-Rheo – Stress relaxation analysis
🔹 i-Rheo GT – G(t) → G*(ω) transformation
🔹 i-Rheo FT – Generic functions
🔜 #AFM, #OpticalTweezers & #MagneticTweezers coming soon!
🌟 It’s time to embrace #Innovation! 😉
i-rheo.mib3avenger.com