I survived meningitis, seemingly unaffected. It took years to understand the true impact.

A MenB vaccine may also help curb drug-resistant gonorrhoea, linking two growing health threats and raising new questions about how vaccines are used.

There have been 20 cases since the weekend in one small area of Kent - but this isn't the normal pattern, so what could have happened?

Coccidioides meningitis is a life-threatening complication with Coccidioides spp that requires lifelong antifungal therapy. While some cases respond to azoles, others are refractory and require periodic treatment with intravenous and/or intrathecal (IT) amphotericin B. MAT2203 is a novel formulation of amphotericin B that uses a rolled phosphatidylserine lipid nanocrystal bilayer that is orally absorbed. MAT2203 has been successfully used to treat cryptococcal meningitis and Histoplasma meningitis.Case PresentationIn 2017 a previously healthy construction worker developed coccidioidal pneumonia and meningitis and was treated with liposomal amphotericin B and oral fluconazole. His pneumonia resolved, but his meningitis worsened. Imaging showed vasculitis of his middle cerebral artery and arachnoiditis at the base of the brain and eventually throughout his spine. He required multiple changes in azoles and eventually an Ommaya reservoir so that he could receive periodic IT amphotericin B plus corticosteroids while continuing oral isavuconazole. Treatment response was monitored with symptoms, cerebral spinal fluid (CSF) cell counts, CSF Coccidioides antigen, and imaging. Frequency of IT treatment varied over the course of his illness from 3 times per week to monthly, increasing with symptom flares. A trial of the investigational antifungal olorofim also failed. In 2024, 1 month after his last dose of IT amphotericin B, the patient started treatment with MAT2203. After 6 months of MAT2203 (without any IT or intravenous amphotericin B), Coccidioides antigen in the ventricular CSF was undetectable for the first time and remained so with normalization of glucose and cell counts.ConclusionsMAT2203 may offer an oral therapeutic option for refractory cases of Coccidioides meningitis.

The publication of a phase 3 trial by Terry Nolan and colleagues in The Lancet Infectious Diseases marks a key step towards licensing a new GSK vaccine (MenABCWY) which targets five Neisseria meningit...

Streptococcus pneumoniae has been estimated to cause 9·18 million cases of pneumococcal pneumonia, meningitis, and invasive non-pneumonia non-meningit…

“Türkmenistan” awiakompaniýasy haj we umra zyýaratyny amala aşyrmak üçin Saud Arabystanyna gitmekçi bolýan zyýaratçylar üçin täze lukmançylyk talaplarynyň girizilendigini habar berdi. “Biznes Türkmenistan” neşiriniň awiakompaniýanyň metbugat gullugyna salgylanyp ýazmagyna görä, täze düzgüne laýyklykda, zyýaratçylar poliowirusa, meningokal meningit we sary gyzzyrma kesellerine garşy lukmançylyk sanjymlarynyň geçirilendigi hakynda güwänama almaga borçly edildi. Täze talaplar baradaky...

Herr Gilchrist, en före detta wicketkeeper, sa att Martin var i ”mycket gott skick” och att medicinsk personal var hoppfull om att han skulle kunna flytta från intensivvården, vilket visade ”vilken fantastisk återhämtning han har gjort och hur snabbt han har återhämtat sig”. Meningit är en infektion i de skyddande hinnorna som omger hjärnan och ryggmärgen. Debuten är plötslig och kan leda till döden inom några timmar om den inte behandlas omedelbart.

11-year-old Yaman was evacuated to Damascus from the town of Madaya for treatment, but his family was left behind and don’t know where to turn.

Two specialist schools have closed as a precaution after a possible link to a case of meningitis was discovered.

Invasive meningitis is classed as an urgent notifiable disease under Health Protection Regulations 2010, meaning suspected cases must be reported without waiting for test confirmation.

L'Organizzazione Mondiale della Sanità torna a parlare di meningite sul suo portale con un bilancio dell'impatto della malattia.