#metagraph
Metagraph: the new search engine that can quickly sift through the staggering volumes of biological data housed in public repositories

go.nature.com/48lM8Kh
‘Google for DNA’ brings order to biology’s big data
MetaGraph compresses vast data archives into a search engine for scientists, opening up new frontiers of biological discovery.
go.nature.com
October 8, 2025 at 4:22 PM
After years of research and continuous refinement, we’re thrilled to share that our paper on the MetaGraph framework — enabling Petabase-scale search across sequencing data — has been published today in Nature (www.nature.com/articles/s41...)
Efficient and accurate search in petabase-scale sequence repositories - Nature
MetaGraph enables scalable indexing of large sets of DNA, RNA or protein sequences using annotated de Bruijn graphs.
www.nature.com
October 8, 2025 at 8:56 PM
The Metagraph paper is out in Nature; it showed up in my feeds today! Congratulations to Mikhail Karasikov, @gxxxr.bsky.social, @akkah21.bsky.social and all of the other authors (whom I'd love to follow on Bluesky if I can find you ;P) www.nature.com/articles/s41...
Efficient and accurate search in petabase-scale sequence repositories - Nature
MetaGraph enables scalable indexing of large sets of DNA, RNA or protein sequences using annotated de Bruijn graphs.
www.nature.com
October 9, 2025 at 2:40 PM
Efficient and accurate search in petabase-scale sequence repositories www.nature.com/articles/s41... 🧬🖥️🧪
MetaGraph: metagraph.ethz.ch
Code: github.com/ratschlab/me...
October 9, 2025 at 5:10 PM
Some heated debate at the #iggsy poster session between Andre - Metagraph - Kahles and Evo - Barbell - Garrison!
July 6, 2026 at 7:43 PM
"The Internet has Google. Now biology has MetaGraph. Detailed today in Nature1, the search engine can quickly sift through the staggering volumes of biological data housed in public repositories." 🧪 www.nature.com/articles/d41... anyone try this? What's it like?
‘Google for DNA’ brings order to biology’s big data
MetaGraph compresses vast data archives into a search engine for scientists, opening up new frontiers of biological discovery.
www.nature.com
October 9, 2025 at 10:25 PM
Ca n'est pas si souvent, un article publié dans Nature met ma communauté à l'honneur (la bioinformatique des séquences). Je vous raconte ?
www.nature.com/articles/d41...
‘Google for DNA’ brings order to biology’s big data
MetaGraph compresses vast data archives into a search engine for scientists, opening up new frontiers of biological discovery.
www.nature.com
October 9, 2025 at 3:00 PM
Harun Mustafa presents "Efficient, accurate, SRA-scale indexing and query" at #GI2025
MetaGraph is a highly compressed representation
of all public biological sequences!
nature.com/articles/s41586-025-09603-w
Try it online: metagraph.ethz.ch/search
November 6, 2025 at 4:09 PM
We invite you to try out Metagraph at metagraph.ethz.ch, learn more about our framework in the paper (nature.com/articles/s41...) or start building your own indexes from your own data (github.com/ratschlab/me...).
MetaGraph - Biological Sequence Search
Petabase-Scale Search for DNA, RNA & Amino acids
metagraph.ethz.ch
October 8, 2025 at 8:56 PM
MetaGraph by Karasikov and coauthors makes the world’s DNA searchable. By turning 67 petabases of raw sequences into a compressed graph structure, it enables fast, low-cost search across global genomic data—bringing biology closer to having its own “search engine”. www.nature.com/articles/s41...
Efficient and accurate search in petabase-scale sequence repositories - Nature
MetaGraph enables scalable indexing of large sets of DNA, RNA or protein sequences using annotated de Bruijn graphs.
www.nature.com
October 13, 2025 at 12:20 PM
A Bittensor mining app is a stack: miner hotkey registration, metagraph reads, and RPC for chain data plus extrinsics. Public endpoints are fine for testing; production miners usually want a dedicated node or managed RPC. onfinality.io/en/rpc-assis...
September 24, 2026 at 10:09 PM
A paper in Nature presents MetaGraph, which indexes petabase-scale biological sequences for accurate and efficient searches across vast sequence space 🧪👇
www.nature.com/articles/s41...
Efficient and accurate search in petabase-scale sequence repositories - Nature
MetaGraph enables scalable indexing of large sets of DNA, RNA or protein sequences using annotated de Bruijn graphs.
www.nature.com
October 8, 2025 at 4:54 PM
The Internet has Google. Now biology has MetaGraph. Detailed today in Nature1, the search engine can quickly sift through the staggering volumes of biological data housed in public repositories.

www.nature.com/articles/d41...
‘Google for DNA’ brings order to biology’s big data
MetaGraph compresses vast data archives into a search engine for scientists, opening up new frontiers of biological discovery.
www.nature.com
October 13, 2025 at 6:48 AM
Modern biology produces vast amounts of raw sequencing data — genomes, transcriptomes, and protein sequences. MetaGraph provides a unified computational framework to index, query, and reason across this landscape of biological information.
October 8, 2025 at 8:56 PM
We show that MetaGraph indexes are both scalable and cost-efficient for querying. We Searching 1 Mbp of sequence against the entire SRA costs less than $1 on standard cloud infrastructure — making Petabase-scale biological data truly searchable and accessible.
October 8, 2025 at 8:56 PM
🌐 Complex Systems Modeling:

• Multi-scale representation (micro to macro)
• Ecological networks & dependencies
• Sustainable infrastructure
• Healthcare system interdependencies

Model the complexity that matters.

#ComplexSystems #DataScience #metagraph
December 1, 2025 at 7:37 AM
At its core, MetaGraph represents all input sequences as labeled, succinct de Bruijn graphs — a highly compressed yet fully searchable structure. Each k-mer carries metadata labels that remain interactively queryable through a flexible API.
October 8, 2025 at 8:56 PM
🔎 Check out MetaGraph – a powerful search engine for DNA, RNA and protein sequences in large public repositories. This important milestone in computational genomics was published in Nature, by SIB scientists at ETH Zurich.
A fast, accurate ‘sequence search engine’
The MetaGraph tool can search through millions of published DNA, RNA and protein records in a matter of seconds. Developed by SIB scientists at ETH Zurich, the tool overcomes current limitations in an...
www.sib.swiss
October 13, 2025 at 9:04 AM
"Google for DNA" -- this sounds incredible!!
www.nature.com/articles/d41...
‘Google for DNA’ brings order to biology’s big data
MetaGraph compresses vast data archives into a search engine for scientists, opening up new frontiers of biological discovery.
www.nature.com
October 10, 2025 at 1:15 AM
🧪MetaGraph compresses and organizes genomic sequence data into a searchable format, enabling efficient scanning on personal computers. This tool indexes sequences from diverse organisms, streamlining genomic research. 🧬🖥️
‘Google for DNA’ indexes 10% of world’s known genetic sequences
Achievement demonstrates feasibility of making all of life’s code easily searchable, researchers say
www.science.org
June 10, 2024 at 4:54 PM
Druva has launched MetaGraph, a secure metadata intelligence layer that works with its DruAI Agents to turn backup data into real-time insights, enabling faster cyber, compliance, and operational decisions.
virtualizationreview.com/Articles/202...

#Druva #MetaGraph #DataSecurity #TechNews
Druva Launches MetaGraph to Advance Agentic Data Security -- Virtualization Review
Druva has launched MetaGraph, a secure metadata intelligence layer that works with its DruAI Agents to turn backup data into real-time insights, enabling faster cyber, compliance, and operational deci...
virtualizationreview.com
September 17, 2025 at 5:30 PM
(Okay more properly it‘s a metagraph. But also hypergraphs. Meta-hypergraphs.)
November 6, 2025 at 7:15 AM