The clinical translation of cellular immunotherapies for solid tumors remains limited by the lack of adequate tools to evaluate therapeutic function within the native tumor microenvironment. Here, we ...

The clinical translation of cellular immunotherapies for solid tumors remains limited by the lack of adequate tools to evaluate therapeutic function within the native tumor microenvironment. Here, we ...

Fibre integrated circuits created by first preparing circuitry on extremely thin and flexible substrates and then mechanically rolling them up demonstrate microdevice density reaching 100,000 transistors per centimetre and excellent stability under harsh service conditions.

NIH team and colleagues believe microdevice may improve upon existing placenta models.

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Many applications—from drug discovery and diagnostics to cell engineering and gene modulation—require delivering biomolecules into large numbers of cells and rapidly evaluating the outcomes. The challenge is two-fold: achieve intracellular delivery at scale across diverse cells and cargoes, and obtain quantitative results fast enough to keep pace with that delivery.

A microdevice loaded with small doses of drugs and drug combinations then implanted in a tumor can show which therapies work best in a specific tumor type. In this image, dead tumor cells (red) surround the area where the device was inserted and drugs were released. Credit: Max J. Cotler, Khalil B. Ramadi, Elena Christodoulopoulos, Sebastian W. Ahn, Oliver Jonas, and Michael J. Cima

Researchers at Concordia University have developed a 3D printing technique that uses focused ultrasound to fabricate microscale structures on soft polymers.

Ultra-fine bubbles tune how inkjet droplets dry, reshaping particle films without additives and improving microdevice printing while avoiding contamination.

The temperature coefficient of resistance (TCR) procedure was employed to evaluate the operational temperature of the microdevice at a specific voltage. The heater integrated into the sensor shows a linear TCR. Electrical resistance was monitored using a source meter while...