The devil's monotherapy
December 3, 2024 at 9:50 PM
The devil's monotherapy
As a radom aside, it genuinely blows my mind that monotherapy isn't the go to starting regimen for trans women.
December 5, 2024 at 6:48 PM
As a radom aside, it genuinely blows my mind that monotherapy isn't the go to starting regimen for trans women.
how to do monotherapy estradiol wikihow monotherapy estrogens level what levels for good HRT injection mtf estrogen snatched waist big titty immortal
February 27, 2025 at 3:25 AM
how to do monotherapy estradiol wikihow monotherapy estrogens level what levels for good HRT injection mtf estrogen snatched waist big titty immortal
the second i started injection monotherapy my transition essentially exploded.
going down the 'correct' path basically stunted my transition.
going down the 'correct' path basically stunted my transition.
I suspect the only reason I've had a more "effective" transition than several of my peers is because I went on injection monotherapy as soon as I could, and so I had actual feminizing and not menopausal levels oestrogen from the first year 🤷♀️
As far as I've been able to determine the main healthcare risk endocrinologists are worried about regarding DIY HRT is that you might get an effective dose without months to years of fucking around.
March 2, 2026 at 10:20 AM
the second i started injection monotherapy my transition essentially exploded.
going down the 'correct' path basically stunted my transition.
going down the 'correct' path basically stunted my transition.
I've escaped the spironolacrum
(doing monotherapy)
(doing monotherapy)
March 1, 2026 at 12:10 AM
I've escaped the spironolacrum
(doing monotherapy)
(doing monotherapy)
monotherapy and sports bettinggggg
May 11, 2025 at 3:57 PM
monotherapy and sports bettinggggg
best AA is injecting estrogen. this post brought to you by monotherapy clan gang
April 11, 2025 at 9:45 AM
best AA is injecting estrogen. this post brought to you by monotherapy clan gang
4 years on HRT monotherapy...
Time to see what progesterone does
Time to see what progesterone does
April 30, 2025 at 11:41 PM
4 years on HRT monotherapy...
Time to see what progesterone does
Time to see what progesterone does
diy monotherapy estradiol enanthate girl who is dating a low-dose sublingual estradiol with high amounts of spiro girl
May 15, 2025 at 5:48 PM
diy monotherapy estradiol enanthate girl who is dating a low-dose sublingual estradiol with high amounts of spiro girl
3. On closer examination, the evidence reviews appear to be an extreme example of politically-manufactured science. Across the 10 reviews, 547 full-text screenings resulted in just 17 studies included—a staggering 97% exclusion rate.
March 10, 2026 at 4:26 PM
3. On closer examination, the evidence reviews appear to be an extreme example of politically-manufactured science. Across the 10 reviews, 547 full-text screenings resulted in just 17 studies included—a staggering 97% exclusion rate.
friendship ended with estrogen spray as it took me out of monotherapy testosterone suppression. luckily patches are back in norway
February 16, 2025 at 9:25 AM
friendship ended with estrogen spray as it took me out of monotherapy testosterone suppression. luckily patches are back in norway
I suspect the only reason I've had a more "effective" transition than several of my peers is because I went on injection monotherapy as soon as I could, and so I had actual feminizing and not menopausal levels oestrogen from the first year 🤷♀️
As far as I've been able to determine the main healthcare risk endocrinologists are worried about regarding DIY HRT is that you might get an effective dose without months to years of fucking around.
Many transition via DIY resources. I've never seen an endocrinologist or a psych because I don't want to go through a combative and adversarial diagnostic process to access what I need.
The healthcare risks are along the lines of "increased risk of breast cancer because I have breasts now."
The healthcare risks are along the lines of "increased risk of breast cancer because I have breasts now."
March 2, 2026 at 10:16 AM
I suspect the only reason I've had a more "effective" transition than several of my peers is because I went on injection monotherapy as soon as I could, and so I had actual feminizing and not menopausal levels oestrogen from the first year 🤷♀️
> Cialis monotherapy
> powers & blanchard are the same person
lmfao
> powers & blanchard are the same person
lmfao
November 11, 2023 at 7:14 AM
> Cialis monotherapy
> powers & blanchard are the same person
lmfao
> powers & blanchard are the same person
lmfao
monotherapy girlies get it done!!!
June 14, 2026 at 2:19 AM
monotherapy girlies get it done!!!
im going to be the first person with adult adhd to be successfully treated with guanfacine monotherapy. I can feel it.
November 15, 2025 at 7:11 PM
im going to be the first person with adult adhd to be successfully treated with guanfacine monotherapy. I can feel it.
S'what im doin yeah, monotherapy through injections is just all round more practical it seems
September 27, 2026 at 1:29 AM
S'what im doin yeah, monotherapy through injections is just all round more practical it seems
You think he's doing estrogen monotherapy or sticking with spiro?
November 8, 2024 at 5:28 AM
You think he's doing estrogen monotherapy or sticking with spiro?
first labs are back and it's another W for estrogen monotherapy 🙂↕️ antiandrogens confirmed washed up
April 27, 2025 at 8:09 PM
first labs are back and it's another W for estrogen monotherapy 🙂↕️ antiandrogens confirmed washed up
girlies who use injection monotherapy LOVE gluten free mac and cheese
February 5, 2024 at 1:17 AM
girlies who use injection monotherapy LOVE gluten free mac and cheese
New today on lower LDL cholesterol, the better by systematically reviewing all data for statins plus ezetimibe vs stains alone and showing reduction of combined for all-cause mortality, CV mortality, stroke, and major adverse CV outcomes
www.mayoclinicproceedings.org/article/S002...
www.mayoclinicproceedings.org/article/S002...
Impact of Lipid-Lowering Combination Therapy With Statins and Ezetimibe vs Statin Monotherapy on the Reduction of Cardiovascular Outcomes: A Meta-analysis
To evaluate the efficacy of combination lipid-lowering therapy (LLT) compared with
statin monotherapy for low-density lipoprotein cholesterol (LDL-C) reduction, associated
adverse events, and outcomes...
www.mayoclinicproceedings.org
March 23, 2025 at 11:43 PM
New today on lower LDL cholesterol, the better by systematically reviewing all data for statins plus ezetimibe vs stains alone and showing reduction of combined for all-cause mortality, CV mortality, stroke, and major adverse CV outcomes
www.mayoclinicproceedings.org/article/S002...
www.mayoclinicproceedings.org/article/S002...
i would eventually like to get to monotherapy so i'm seeing if i can tank the inevitable mood swings this will be giving me
September 27, 2026 at 10:02 PM
i would eventually like to get to monotherapy so i'm seeing if i can tank the inevitable mood swings this will be giving me
Estradiol monotherapy stops my body from making testosterone and IMO the DEA should be giving me a grant for shutting down the manufacture of a controlled substance
January 23, 2025 at 6:31 AM
Estradiol monotherapy stops my body from making testosterone and IMO the DEA should be giving me a grant for shutting down the manufacture of a controlled substance
I'm going to start with the "evidence review" papers, of which there are 10. The first one is about oestrogen monotherapy...
www.england.nhs.uk
March 22, 2026 at 7:44 AM
I'm going to start with the "evidence review" papers, of which there are 10. The first one is about oestrogen monotherapy...
Nope. Estrogen monotherapy is a thing. It is capable of reducing testosterone below cis women's testosterone levels. Come back after you've studied up.
August 16, 2026 at 2:33 PM
Nope. Estrogen monotherapy is a thing. It is capable of reducing testosterone below cis women's testosterone levels. Come back after you've studied up.
3/ While NHS England claims to have commissioned 10 evidence reviews, several topics are clinically nonsensical. The review titled “GnRH analogue monotherapy for CYP with gender incongruence - non-binary partial masculinisation” targets a treatment pathway that is non-existent in practice.
March 9, 2026 at 7:21 PM
3/ While NHS England claims to have commissioned 10 evidence reviews, several topics are clinically nonsensical. The review titled “GnRH analogue monotherapy for CYP with gender incongruence - non-binary partial masculinisation” targets a treatment pathway that is non-existent in practice.