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mthman.bsky.social
Question of the day!! #mschat #EduSky
November 10, 2026 at 11:11 PM
mthman.bsky.social
Question of the day!! #mschat #EduSky
November 9, 2026 at 11:51 PM
mthman.bsky.social
Question of the day!! #mschat #EduSky
November 6, 2026 at 10:28 PM
mthman.bsky.social
#mschat #EduSky
November 4, 2026 at 7:57 PM
mthman.bsky.social
Question of the day!! #mschat #EduSky
November 4, 2026 at 10:28 PM
gregoryai.bsky.social
Noro Psikiyatr Ars. 2026 Oct 5;63:584-589. doi: 10.29399/npa.29424. eCollection 2026. ABSTRACT INTRODUCTION: Multiple Sclerosis (MS) is a chronic autoimmune disorder marked by neuroinflammation, demyelination, and neurodegeneration. Zinc...
#MSchat #MS #Neurology #MultipleSclerosis #NeuroSky #MedSky
Zinc Supplementation Attenuates Pro-Inflammatory Cytokine Responses in a Cuprizone-Induced Rat Model of Multiple Sclerosis
Noro Psikiyatr Ars. 2026 Oct 5;63:584-589. doi: 10.29399/npa.29424. eCollection 2026. ABSTRACT INTRODUCTION: Multiple Sclerosis (MS) is a chronic autoimmune disorder marked by neuroinflammation, demyelination, and neurodegeneration. Zinc is crucial for immune regulation, but its impact on inflamm...
brain-regeneration.com
November 8, 2026 at 8:00 AM
gregoryai.bsky.social
New clinical trial
Exploring Therapeutic Change Following Psychodrama in Multiple Sclerosis: A Mixed-Methods Study With 6-Month Follow-Up

#ClinicalTrials #MultipleSclerosis #MSchat #Neurology
Exploring Therapeutic Change Following Psychodrama in Multiple Sclerosis: A Mixed-Methods Study With 6-Month Follow-Up
This single-group, mixed-methods study explored changes following a 13-week group psychodrama programme in adults with relapsing-remitting multiple sclerosis (MS). Participants were recruited from the demyelinating diseases unit of Mersin University Hospital, Türkiye, and att...
brain-regeneration.com
November 10, 2026 at 6:50 PM
gregoryai.bsky.social
New clinical trial
THE EFFECTS OF TAI CHI ON EXECUTIVE FUNCTIONS IN INDIVIDUALS WITH MULTIPLE SCLEROSIS: A RANDOMIZED CONTROLLED TRIAL

#ClinicalTrials #MultipleSclerosis #MSchat #Neurology
THE EFFECTS OF TAI CHI ON EXECUTIVE FUNCTIONS IN INDIVIDUALS WITH MULTIPLE SCLEROSIS: A RANDOMIZED CONTROLLED TRIAL
This study aimed to evaluate the effects of Tai Chi exercise on cognitive functions, fatigue, and depressive symptoms in individuals with Multiple Sclerosis (MS). MS is a chronic neurological disease characterized by demyelination within the central nervous system and is frequ...
brain-regeneration.com
November 11, 2026 at 8:00 AM
gregoryai.bsky.social
New clinical trial
Evaluating Functional Outcomes and Clinical Feasibility of the Zeen Mobility Device in Outpatient Rehabilitation

#ClinicalTrials #MultipleSclerosis #MSchat #Neurology
Evaluating Functional Outcomes and Clinical Feasibility of the Zeen Mobility Device in Outpatient Rehabilitation
The goal of this clinical trial is to learn whether the Zeen Mobility Device can improve mobility and function during outpatient rehabilitation for adults with mobility impairments. The study will also evaluate the safety of the device and how easy it is for participants and t...
brain-regeneration.com
November 6, 2026 at 6:50 PM
gregoryai.bsky.social
Oligodendrocyte precursor cells (OPCs) are a widely distributed glial population in the adult central nervous system that retain the ability to differentiate into mature oligodendrocytes (OLs), or under pathological conditions, adopt alt...
#MSchat #MS #Neurology #MultipleSclerosis #NeuroSky #MedSky
Opposing BMP and Wnt signaling drive astrocyte-like phenotypic transition of oligodendrocyte precursor cells at the expense of remyelination in a mouse model of demyelination
Oligodendrocyte precursor cells (OPCs) are a widely distributed glial population in the adult central nervous system that retain the ability to differentiate into mature oligodendrocytes (OLs), or under pathological conditions, adopt alternative phenotypic transition. The post-injury phenotype of...
brain-regeneration.com
November 12, 2026 at 6:40 PM
gregoryai.bsky.social
New clinical trial
Exploring Mechanisms and Fatigue Management Strategies Through a Tele-rehabilitation Program in People With Multiple Sclerosis and Mild Disability

#ClinicalTrials #MultipleSclerosis #MSchat #Neurology
Exploring Mechanisms and Fatigue Management Strategies Through a Tele-rehabilitation Program in People With Multiple Sclerosis and Mild Disability
MS-FatigueCARE is a prospective, multicenter study aimed at investigating the mechanisms underlying fatigue in people with multiple sclerosis (MS) and mild disability, and at evaluating the efficacy of a personalized home-based telerehabilitation program. Fatigue is one of the...
brain-regeneration.com
November 10, 2026 at 8:00 AM
mthman.bsky.social
Question of the day!! #mschat #EduSky
November 4, 2026 at 12:06 AM
gregoryai.bsky.social
ABSTRACT Multiple sclerosis (MS) is an autoimmune disease of the central nervous system characterized by progressive demyelination and neurodegenerative damage. The accumulation of reactive oxygen species (ROS) and the resulting oxidativ...
#MSchat #MS #Neurology #MultipleSclerosis #NeuroSky #MedSky
Astragalus Polysaccharide Exerts a Neuroprotective Effect in a Demyelination Model by Alleviating Oxidative Stress
ABSTRACT Multiple sclerosis (MS) is an autoimmune disease of the central nervous system characterized by progressive demyelination and neurodegenerative damage. The accumulation of reactive oxygen species (ROS) and the resulting oxidative stress are considered key contributors to myelin injury an...
brain-regeneration.com
November 9, 2026 at 1:30 PM
gregoryai.bsky.social
New clinical trial
Investigating the Acute and Long-term Effects of Treadmill-integrated Virtual Reality (VR) Training on Real-World Mobility and Fall-Related Outcomes in People With Multiple Sclerosis

#ClinicalTrials #MultipleSclerosis #MSchat #Neurology
Investigating the Acute and Long-term Effects of Treadmill-integrated Virtual Reality (VR) Training on Real-World Mobility and Fall-Related Outcomes in People With Multiple Sclerosis
This study will test whether a treadmill-based virtual reality walking program is safe, practical, and helpful for people with multiple sclerosis (MS). Participants will complete a 6-week training program and wear smart socks that measure how they walk before, during, and afte...
brain-regeneration.com
November 10, 2026 at 6:40 PM
gregoryai.bsky.social
New clinical trial
Virtual Reality Versus Mental Practice On Balance And Gait In Patients With Multiple Sclerosis

#ClinicalTrials #MultipleSclerosis #MSchat #Neurology
Virtual Reality Versus Mental Practice On Balance And Gait In Patients With Multiple Sclerosis
This study is conducted to: * Investigate the effect of virtual reality based training on balance and risk of falling. * Investigate the effect of virtual reality based training on gait. * Investigate the effect of mental practice on balance and risk of falling. * Investigate ...
brain-regeneration.com
November 6, 2026 at 8:00 AM
gregoryai.bsky.social
Background: Multiple sclerosis (MS) is a chronic, autoimmune disorder that culminates in severe motor and cognitive deficits. The progression of the disease is associated with inflammation and demyelination of the brain and spinal cord. ...
#MSchat #MS #Neurology #MultipleSclerosis #NeuroSky #MedSky
Enkephalin Treatment Reduces Elevated Brain Glia in Mice With Experimental Autoimmune Encephalomyelitis
Background: Multiple sclerosis (MS) is a chronic, autoimmune disorder that culminates in severe motor and cognitive deficits. The progression of the disease is associated with inflammation and demyelination of the brain and spinal cord. Activation and proliferation of glia, including astrocytes a...
brain-regeneration.com
November 6, 2026 at 8:00 AM
gregoryai.bsky.social
Platelets are increasingly recognized as active amplifiers of neuroinflammation in multiple sclerosis and experimental autoimmune encephalomyelitis (EAE). P2Y12 is an essential ADP receptor that regulates platelet activation and is upreg...
#MSchat #MS #Neurology #MultipleSclerosis #NeuroSky #MedSky
Targeting P2Y12 limits TH17 accumulation in the CNS and reduces EAE progression
Platelets are increasingly recognized as active amplifiers of neuroinflammation in multiple sclerosis and experimental autoimmune encephalomyelitis (EAE). P2Y12 is an essential ADP receptor that regulates platelet activation and is upregulated in neuroinflammatory lesions. However, its contributi...
brain-regeneration.com
November 5, 2026 at 6:40 PM
gregoryai.bsky.social
New clinical trial
Treatment of Memory Retrieval Impairments in MS With HDtDCS to the LIFG in a Placebo Controlled Trial

#ClinicalTrials #MultipleSclerosis #MSchat #Neurology
Treatment of Memory Retrieval Impairments in MS With HDtDCS to the LIFG in a Placebo Controlled Trial
The purpose of the study is to test whether low-level electric stimulation, called High Definition transcranial Direct Current Stimulation (HDtDCS), on the part of the brain (i.e., left inferior frontal gyrus) thought to aid in memory will improve verbal retrieval in multiple ...
brain-regeneration.com
November 4, 2026 at 8:20 AM
gregoryai.bsky.social
Life Sci. 2026 Nov 3:124767. doi: 10.1016/j.lfs.2026.124767. Online ahead of print. ABSTRACT AIMS: This study established a reproducible mouse model of posterior limb of the internal capsule (PLIC) ischemia to investigate whether Reelin ...
#MSchat #MS #Neurology #MultipleSclerosis #NeuroSky #MedSky
Reelin-enhanced neural stem cell therapy promotes neuroangiogenesis, remyelination, and functional recovery after subcortical capsular ischemic stroke
Life Sci. 2026 Nov 3:124767. doi: 10.1016/j.lfs.2026.124767. Online ahead of print. ABSTRACT AIMS: This study established a reproducible mouse model of posterior limb of the internal capsule (PLIC) ischemia to investigate whether Reelin potentiates neural stem cell (NSC)-mediated functional and s...
brain-regeneration.com
November 4, 2026 at 8:00 AM
gregoryai.bsky.social
New clinical trial
A Biosimilar Trial to Investigate PK, PD, and Safety with PB018 versus US-licensed Ocrevus® and EU-approved Ocrevus®

#ClinicalTrials #MultipleSclerosis #MSchat #Neurology
A Biosimilar Trial to Investigate PK, PD, and Safety with PB018 versus US-licensed Ocrevus® and EU-approved Ocrevus®
Trial number : 2026-525314-61-00 Overall trial status : Authorised, recruitment pending Trial title : A Biosimilar Trial to Investigate PK, PD, and Safety with PB018 versus US-licensed Ocrevus® and EU-approved Ocrevus® Medical conditions : Multiple sclerosis Status in each c...
brain-regeneration.com
November 3, 2026 at 8:00 AM
gregoryai.bsky.social
Multiple sclerosis (MS) is an autoimmune demyelinating disease characterized by neuroinflammation. Toll-like receptor 4 (TLR4) is a receptor for damage-associated molecular patterns, such as high-mobility group box 1 (HMGB1) and plays a ...
#MSchat #MS #Neurology #MultipleSclerosis #NeuroSky #MedSky
Targeting TLR4 alleviates the progression of experimental autoimmune encephalomyelitis by regulating central resident cells and Th1/Th17 cell differentiation
Multiple sclerosis (MS) is an autoimmune demyelinating disease characterized by neuroinflammation. Toll-like receptor 4 (TLR4) is a receptor for damage-associated molecular patterns, such as high-mobility group box 1 (HMGB1) and plays a role in innate immunity. However, its precise role and cellu...
brain-regeneration.com
October 31, 2026 at 12:40 PM
mthman.bsky.social
Question of the day!! #mschat #EduSky
October 28, 2026 at 9:49 PM
gregoryai.bsky.social
The age-related failure to produce oligodendrocytes from oligodendrocyte progenitor cells (OPCs) is associated with irreversible neurodegeneration in multiple sclerosis (MS). Consequently, regenerative approaches have significant potenti...
#MSchat #MS #Neurology #MultipleSclerosis #NeuroSky #MedSky
Metformin Restores CNS Remyelination Capacity by Rejuvenating Aged Stem Cells
The age-related failure to produce oligodendrocytes from oligodendrocyte progenitor cells (OPCs) is associated with irreversible neurodegeneration in multiple sclerosis (MS). Consequently, regenerative approaches have significant potential for treating chronic demyelinating diseases. Here, we sho...
brain-regeneration.com
October 31, 2026 at 8:20 AM
gregoryai.bsky.social
New clinical trial
A Phase 3 extension study to investigate long-term safety and tolerability of frexalimab in participants with multiple sclerosis.

#ClinicalTrials #MultipleSclerosis #MSchat #Neurology
A Phase 3 extension study to investigate long-term safety and tolerability of frexalimab in participants with multiple sclerosis.
Trial number : 2026-525688-41-00 Overall trial status : Authorised, recruitment pending Trial title : A Phase 3 extension study to investigate long-term safety and tolerability of frexalimab in participants with multiple sclerosis. Medical conditions : multiple sclerosis Statu...
brain-regeneration.com
October 31, 2026 at 8:00 AM
gregoryai.bsky.social
Prog Neurobiol. 2026 Oct 30:102967. doi: 10.1016/j.pneurobio.2026.102967. Online ahead of print. ABSTRACT BACKGROUND: Different types of electrical stimulations (ES), transcranial direct current stimulation (tDCS), vagus nerve stimulatio...
#MSchat #MS #Neurology #MultipleSclerosis #NeuroSky #MedSky
Effect of Electrical Stimulation on Remyelination in Preclinical Models of Multiple Sclerosis: A Systematic Review
Prog Neurobiol. 2026 Oct 30:102967. doi: 10.1016/j.pneurobio.2026.102967. Online ahead of print. ABSTRACT BACKGROUND: Different types of electrical stimulations (ES), transcranial direct current stimulation (tDCS), vagus nerve stimulation (VNS), and peripheral nerve stimulation (PNS) have emerged...
brain-regeneration.com
October 31, 2026 at 8:00 AM