December 16, 2024 at 7:01 AM
Excited to share our paper on the NLRP3 inflammasome condensate at the Microtubule Organizing Center (MTOC) by "precise!" cryo-electron tomography (cryo-ET), in collaboration with Jue (phyllis) Wang in the labs of Grant Jensen (BYU) and Pete Dahlberg (Stanford)! www.science.org/doi/10.1126/...
April 23, 2026 at 6:43 PM
Excited to share our paper on the NLRP3 inflammasome condensate at the Microtubule Organizing Center (MTOC) by "precise!" cryo-electron tomography (cryo-ET), in collaboration with Jue (phyllis) Wang in the labs of Grant Jensen (BYU) and Pete Dahlberg (Stanford)! www.science.org/doi/10.1126/...
Delighted to share our first manuscript on @bsky.app on a novel SUN1-ALLAN complex in Plasmodium MTOC and NE organization. Many thanks @zeeshanm.bsky.social; @eelcotromer.bsky.social; @ryanase.bsky.social ; Tony; Sarah; David F; Karine; Igor; Cyrille; Declan. Link:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
December 6, 2024 at 3:26 PM
Delighted to share our first manuscript on @bsky.app on a novel SUN1-ALLAN complex in Plasmodium MTOC and NE organization. Many thanks @zeeshanm.bsky.social; @eelcotromer.bsky.social; @ryanase.bsky.social ; Tony; Sarah; David F; Karine; Igor; Cyrille; Declan. Link:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
August 4, 2025 at 5:39 PM
December 22, 2025 at 10:53 AM
mtoc 2.0 is out! mtoc brings a visually-rich music library experience to Linux desktop, featuring cover flow with smooth, satisfying animations. 2.0 brings new features including advanced queue management and playlists. Out now on Flathub. 3fz.org/mtoc
July 31, 2025 at 3:26 AM
mtoc 2.0 is out! mtoc brings a visually-rich music library experience to Linux desktop, featuring cover flow with smooth, satisfying animations. 2.0 brings new features including advanced queue management and playlists. Out now on Flathub. 3fz.org/mtoc
Excited to share our publication @lsajournal.org showing that divergent Plasmodium kinases drive MTOC, kinetochore and axoneme organisation during male gamete formation. Many thanks, @ritatewari.bsky.social, @davidguttery.bsky.social, @zeeshanm.bsky.social, Tony and David F.
doi.org/10.26508/lsa...
doi.org/10.26508/lsa...
March 25, 2025 at 9:53 AM
Excited to share our publication @lsajournal.org showing that divergent Plasmodium kinases drive MTOC, kinetochore and axoneme organisation during male gamete formation. Many thanks, @ritatewari.bsky.social, @davidguttery.bsky.social, @zeeshanm.bsky.social, Tony and David F.
doi.org/10.26508/lsa...
doi.org/10.26508/lsa...
mtoc 2.1 is out! new in this update:
- compact layout mode with increased iPod vibes, ideal for small widths and tiling use
- light mode
small improvements:
- optimized cover flow with better antialiasing
- contextual information in queue header
- navigation refinements
3fz.org/mtoc
#linux #indiedev
- compact layout mode with increased iPod vibes, ideal for small widths and tiling use
- light mode
small improvements:
- optimized cover flow with better antialiasing
- contextual information in queue header
- navigation refinements
3fz.org/mtoc
#linux #indiedev
August 7, 2025 at 7:12 PM
mtoc 2.1 is out! new in this update:
- compact layout mode with increased iPod vibes, ideal for small widths and tiling use
- light mode
small improvements:
- optimized cover flow with better antialiasing
- contextual information in queue header
- navigation refinements
3fz.org/mtoc
#linux #indiedev
- compact layout mode with increased iPod vibes, ideal for small widths and tiling use
- light mode
small improvements:
- optimized cover flow with better antialiasing
- contextual information in queue header
- navigation refinements
3fz.org/mtoc
#linux #indiedev
Gautam Dey @gautamdey.bsky.social discussed spindle evolutionary dynamics. In Chlamy, an MTOC forms in prophase to nucleate the spindle, but remains tethered to the basal bodies. By using ExM, they plan to expand every microbial eukaryote on Earth! #SpindleCroatia2026
April 15, 2026 at 7:42 AM
Gautam Dey @gautamdey.bsky.social discussed spindle evolutionary dynamics. In Chlamy, an MTOC forms in prophase to nucleate the spindle, but remains tethered to the basal bodies. By using ExM, they plan to expand every microbial eukaryote on Earth! #SpindleCroatia2026
Osteocytes also have a nuclear envelope #MTOC. #cytoskeleton
Structure of microtubules around the osteoclast nuclear envelope influences their bone resorption function
📸 Silvia Vergarajauregui et al Friedrich-Alexander-Universität Erlangen-Nürnberg in @jcellsci.bsky.social
➡️ bpod.org.uk/archive/2026...
📸 Silvia Vergarajauregui et al Friedrich-Alexander-Universität Erlangen-Nürnberg in @jcellsci.bsky.social
➡️ bpod.org.uk/archive/2026...
BPoD | Solving Bone Dissolving
Solving Bone Dissolving - Biomedical pictures for April 2026.
bpod.org.uk
May 1, 2026 at 11:03 AM
Osteocytes also have a nuclear envelope #MTOC. #cytoskeleton
Spindle-localized F-actin regulates polar MTOC organization and the fidelity of meiotic spindle formation https://www.biorxiv.org/content/10.1101/2025.05.07.652730v1
May 11, 2025 at 8:30 PM
Spindle-localized F-actin regulates polar MTOC organization and the fidelity of meiotic spindle formation https://www.biorxiv.org/content/10.1101/2025.05.07.652730v1
Our new preprint describes Plasmodium NEK4 as a key regulator coupling meiotic initiation and morphogenesis—a critical step for malaria transmission. This involves MTOC-driven nuclear movement strikingly analogous to "horsetail" movement in fission yeast.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
November 24, 2025 at 4:08 PM
Our new preprint describes Plasmodium NEK4 as a key regulator coupling meiotic initiation and morphogenesis—a critical step for malaria transmission. This involves MTOC-driven nuclear movement strikingly analogous to "horsetail" movement in fission yeast.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
"The offices where I made my petition owe their allegiance to residents of states as far away as Kentucky and Texas. They have no vested interest in D.C.’s 702,000 residents and our desire to govern ourselves. That is clearly not what democracy looks like." 51st.news/opinion-mtoc...
Opinion: What I learned about democracy walking the halls of Congress
In seven short months, I had gone from being among the “dregs” of society to getting an audience with the people who help make this country’s laws.
51st.news
October 26, 2025 at 7:30 PM
"The offices where I made my petition owe their allegiance to residents of states as far away as Kentucky and Texas. They have no vested interest in D.C.’s 702,000 residents and our desire to govern ourselves. That is clearly not what democracy looks like." 51st.news/opinion-mtoc...
Non canonical Sun1-Allan complex orchestrates nuclear envelope remodelling and Basal Body/MTOC Segregation during rapid mitosis in Plasmodium
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Non canonical Sun1-Allan complex orchestrates nuclear envelope remodelling and Basal Body/MTOC Segregation during rapid mitosis in Plasmodium
Mitosis in eukaryotes involves reorganization of the nuclear envelope (NE) and microtubule-organizing centers (MTOCs). In Plasmodium, the causative agent of malaria, male gametogenesis features an exc...
www.biorxiv.org
December 5, 2024 at 8:08 PM
Non canonical Sun1-Allan complex orchestrates nuclear envelope remodelling and Basal Body/MTOC Segregation during rapid mitosis in Plasmodium
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
me and cesare: 🙄
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#ludenvoid on #Twitch #mafiatheoldcountry #mtoc #ps5 #smallgamer #vtuber #engvtuber
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#ludenvoid on #Twitch #mafiatheoldcountry #mtoc #ps5 #smallgamer #vtuber #engvtuber
August 27, 2025 at 1:03 PM
me and cesare: 🙄
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#ludenvoid on #Twitch #mafiatheoldcountry #mtoc #ps5 #smallgamer #vtuber #engvtuber
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#ludenvoid on #Twitch #mafiatheoldcountry #mtoc #ps5 #smallgamer #vtuber #engvtuber
Excited to share our latest work led by our talented PhD student @ejsm9.bsky.social We show that Myosins X/VIIb localize F-actin to the spindle&MTOCs in oocytes. With photoswitchable Optojasp, we reveal that spindle/MTOC-localized F-actin drives spindle pole focusing &accurate chromosome segregation
Spindle-localized F-actin regulates polar MTOC organization and the fidelity of meiotic spindle formation - Nature Communications
Errors in oocyte division can cause infertility and birth defects. Here, authors combine a genetic strategy with a novel optochemical tool to show that spindle pole-localized F-actin is essential for ...
www.nature.com
September 19, 2025 at 2:08 PM
Excited to share our latest work led by our talented PhD student @ejsm9.bsky.social We show that Myosins X/VIIb localize F-actin to the spindle&MTOCs in oocytes. With photoswitchable Optojasp, we reveal that spindle/MTOC-localized F-actin drives spindle pole focusing &accurate chromosome segregation
Coming soon: mtoc 2.5 will include a favorites feature. Click the heart to add tracks to a dynamic playlist. The filled heart is tinted with your system accent color 💜
December 4, 2025 at 9:03 AM
Coming soon: mtoc 2.5 will include a favorites feature. Click the heart to add tracks to a dynamic playlist. The filled heart is tinted with your system accent color 💜
Hello world! This is the official account for mtoc, a music player and library browsing app for Linux. Stay tuned for feature highlights, release notes, and development progress. mtoc aims to create a polished, visually-pleasing music experience with album art in the spotlight. Find it on Flathub.
October 5, 2025 at 5:04 AM
Hello world! This is the official account for mtoc, a music player and library browsing app for Linux. Stay tuned for feature highlights, release notes, and development progress. mtoc aims to create a polished, visually-pleasing music experience with album art in the spotlight. Find it on Flathub.
My favourite music player @mtoc.app now has lyrics support and many more new features!
AND most importantly, mtoc is libre software (GPL-3.0). Get it on flathub:
flathub.org/en/apps/org....
AND most importantly, mtoc is libre software (GPL-3.0). Get it on flathub:
flathub.org/en/apps/org....
October 15, 2025 at 4:14 AM
My favourite music player @mtoc.app now has lyrics support and many more new features!
AND most importantly, mtoc is libre software (GPL-3.0). Get it on flathub:
flathub.org/en/apps/org....
AND most importantly, mtoc is libre software (GPL-3.0). Get it on flathub:
flathub.org/en/apps/org....
mtoc 2.6 introduces a playback history list. quickly access your recent plays, open history and queue by clicking the left and right of the artwork, enqueue your history in reverse order.
January 11, 2026 at 9:59 PM
mtoc 2.6 introduces a playback history list. quickly access your recent plays, open history and queue by clicking the left and right of the artwork, enqueue your history in reverse order.
Supranumerary #centrosomes in dendritic cells at the immune synapse- power to the PCM, increased MTOC abilities and signalling on multi-partner contacts. All amazingly centred, not polarised. Masterful talk @isabel-stoetzel.bsky.social
ICYMI: doi.org/10.1038/s414...
#UKCilia2026 /3
ICYMI: doi.org/10.1038/s414...
#UKCilia2026 /3
April 21, 2026 at 5:28 PM
Supranumerary #centrosomes in dendritic cells at the immune synapse- power to the PCM, increased MTOC abilities and signalling on multi-partner contacts. All amazingly centred, not polarised. Masterful talk @isabel-stoetzel.bsky.social
ICYMI: doi.org/10.1038/s414...
#UKCilia2026 /3
ICYMI: doi.org/10.1038/s414...
#UKCilia2026 /3
It's finally coming together, release date is later this week. mtoc 2.0 status:
✅ feature freeze
✅ integration testing
✅ system testing
✅ black box testing
✅ exploratory testing
✅ code review
🟨 acceptance testing
🟨 vibe check
🟨 packaging and release
✅ feature freeze
✅ integration testing
✅ system testing
✅ black box testing
✅ exploratory testing
✅ code review
🟨 acceptance testing
🟨 vibe check
🟨 packaging and release
July 22, 2025 at 4:54 PM
It's finally coming together, release date is later this week. mtoc 2.0 status:
✅ feature freeze
✅ integration testing
✅ system testing
✅ black box testing
✅ exploratory testing
✅ code review
🟨 acceptance testing
🟨 vibe check
🟨 packaging and release
✅ feature freeze
✅ integration testing
✅ system testing
✅ black box testing
✅ exploratory testing
✅ code review
🟨 acceptance testing
🟨 vibe check
🟨 packaging and release