Our groundbreaking Dark Sectioning technique is now published in Nature Methods! 🎉 It supercharges existing imaging systems:
🔬 Widefield → Confocal
🔬 Single-photon → Multiphoton
🔬 2D-SIM → 3D-SIM
Now integrated in Airy PolarSIM and #FlexSIM!
doi.org/10.1038/s415...
#Microscopy #Fluorescence
🔬 Widefield → Confocal
🔬 Single-photon → Multiphoton
🔬 2D-SIM → 3D-SIM
Now integrated in Airy PolarSIM and #FlexSIM!
doi.org/10.1038/s415...
#Microscopy #Fluorescence
May 16, 2025 at 3:03 AM
Our groundbreaking Dark Sectioning technique is now published in Nature Methods! 🎉 It supercharges existing imaging systems:
🔬 Widefield → Confocal
🔬 Single-photon → Multiphoton
🔬 2D-SIM → 3D-SIM
Now integrated in Airy PolarSIM and #FlexSIM!
doi.org/10.1038/s415...
#Microscopy #Fluorescence
🔬 Widefield → Confocal
🔬 Single-photon → Multiphoton
🔬 2D-SIM → 3D-SIM
Now integrated in Airy PolarSIM and #FlexSIM!
doi.org/10.1038/s415...
#Microscopy #Fluorescence
Multiphoton
Ninja
Streaking
Quark
Intragalactic
Why, yes, I think that describes quite the vibe.
Ninja
Streaking
Quark
Intragalactic
Why, yes, I think that describes quite the vibe.
Find the 5 words from your birth year that perfectly describe YOUR vibe ⬇️
www.merriam-webster.com/time-traveler/
www.merriam-webster.com/time-traveler/
July 31, 2026 at 5:39 PM
Multiphoton
Ninja
Streaking
Quark
Intragalactic
Why, yes, I think that describes quite the vibe.
Ninja
Streaking
Quark
Intragalactic
Why, yes, I think that describes quite the vibe.
Fun fact for multiphoton microscopy geeks: aberrations caused by vertical micro-interfaces appear to be a significant contrast mechanism in polarized THG imaging. 😎
July 16, 2025 at 1:39 PM
Fun fact for multiphoton microscopy geeks: aberrations caused by vertical micro-interfaces appear to be a significant contrast mechanism in polarized THG imaging. 😎
That was a fun project! Thanks to Rob Lees, Adam Packer, and all the co-authors for inviting me to participate.
rdcu.be/edQXi
rdcu.be/edQXi
Standardized measurements for monitoring and comparing multiphoton microscope systems
Nature Protocols - A set of procedures is described here for standardizing the evaluation of multiphoton microscope performance, covering laser power, pulse width optimizations, field of view,...
rdcu.be
March 17, 2025 at 12:08 PM
That was a fun project! Thanks to Rob Lees, Adam Packer, and all the co-authors for inviting me to participate.
rdcu.be/edQXi
rdcu.be/edQXi
Rounding out my academic career with one last multiphoton imaging session before my flight 😅
April 12, 2025 at 3:17 PM
Rounding out my academic career with one last multiphoton imaging session before my flight 😅
Multiphoton control cuts time to build key quantum error correction codes
Read more:
https://quantumzeitgeist.com/waterloo-quantum-error-correction-multiphoton-control/
Read more:
https://quantumzeitgeist.com/waterloo-quantum-error-correction-multiphoton-control/
Multiphoton Control Cuts Time To Build Key Quantum Error Correction Codes
New research demonstrates multiphoton control significantly speeds up the construction of key codes for quantum error correction.
quantumzeitgeist.com
October 2, 2026 at 11:09 AM
Multiphoton control cuts time to build key quantum error correction codes
Read more:
https://quantumzeitgeist.com/waterloo-quantum-error-correction-multiphoton-control/
Read more:
https://quantumzeitgeist.com/waterloo-quantum-error-correction-multiphoton-control/
A practical guide for anyone using multiphoton microscopes: Assess your system performance with quick, affordable tests - ensuring reliable, standardised data across labs.
Out now in @natprot.bsky.social ⬇️
www.nature.com/articles/s41...
Out now in @natprot.bsky.social ⬇️
www.nature.com/articles/s41...
Standardized measurements for monitoring and comparing multiphoton microscope systems - Nature Protocols
A set of procedures is described here for standardizing the evaluation of multiphoton microscope performance, covering laser power, pulse width optimizations, field of view, resolution and photomultip...
www.nature.com
March 17, 2025 at 3:41 PM
A practical guide for anyone using multiphoton microscopes: Assess your system performance with quick, affordable tests - ensuring reliable, standardised data across labs.
Out now in @natprot.bsky.social ⬇️
www.nature.com/articles/s41...
Out now in @natprot.bsky.social ⬇️
www.nature.com/articles/s41...
Great lunch of the Multiphoton microscopy conference speakers at SPIE Photonics West! @digmanlab.bsky.social and many others!
January 27, 2025 at 4:39 AM
Great lunch of the Multiphoton microscopy conference speakers at SPIE Photonics West! @digmanlab.bsky.social and many others!
Comparing multiphoton (2p/3p) imaging systems is often done poorly. labrigger.com/blog/2026/01... E.g., PSFs can be measured differently by different labs, staining quality is by far the biggest determinate on how multiphoton images will look at depth, and so forth. (1/3)
January 21, 2026 at 8:55 PM
Comparing multiphoton (2p/3p) imaging systems is often done poorly. labrigger.com/blog/2026/01... E.g., PSFs can be measured differently by different labs, staining quality is by far the biggest determinate on how multiphoton images will look at depth, and so forth. (1/3)
Brand new online today. The biggest fields-of-view scanned fast, for multiphoton imaging. pacificoptica.com/ventana/
January 26, 2025 at 6:54 PM
Brand new online today. The biggest fields-of-view scanned fast, for multiphoton imaging. pacificoptica.com/ventana/
#FluorescenceFriday Spiderweb-like structure by skin #fibroblasts at IMAG’IC. 🟢 #Collagen I immunofluo + 🟣 #SHG fibrillar collagen, #multiphoton microscopy
Valérie A. @crm-myologie.bsky.social
@institutcochin.bsky.social
@upcite.bsky.social
@inserm.fr
@cnrs.fr
Valérie A. @crm-myologie.bsky.social
@institutcochin.bsky.social
@upcite.bsky.social
@inserm.fr
@cnrs.fr
September 11, 2026 at 12:42 PM
#FluorescenceFriday Spiderweb-like structure by skin #fibroblasts at IMAG’IC. 🟢 #Collagen I immunofluo + 🟣 #SHG fibrillar collagen, #multiphoton microscopy
Valérie A. @crm-myologie.bsky.social
@institutcochin.bsky.social
@upcite.bsky.social
@inserm.fr
@cnrs.fr
Valérie A. @crm-myologie.bsky.social
@institutcochin.bsky.social
@upcite.bsky.social
@inserm.fr
@cnrs.fr
Congratulation to Giulia Galante for her thesis defense about the "Characterization and physico-chemical monitoring of collagen degradation in parchments by polarization-resolved multiphoton microscopy!
April 7, 2025 at 3:55 PM
Congratulation to Giulia Galante for her thesis defense about the "Characterization and physico-chemical monitoring of collagen degradation in parchments by polarization-resolved multiphoton microscopy!
A self-localized ultrafast pencil beam can be applied for near-diffraction-limited, high-throughput volumetric imaging in intact tissues and in vitro models.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Self-localized ultrafast pencil beam for volumetric multiphoton imaging - Nature Methods
A self-localized, ultrafast pencil beam can be readily introduced into multiphoton microscopes and applied for near-diffraction-limited, high-throughput volumetric imaging in intact tissues and in vit...
www.nature.com
May 4, 2026 at 7:06 PM
A self-localized ultrafast pencil beam can be applied for near-diffraction-limited, high-throughput volumetric imaging in intact tissues and in vitro models.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Chromatically Corrected Multicolor Multiphoton Microscopy
pubs.acs.org/doi/full/10....
pubs.acs.org/doi/full/10....
November 11, 2023 at 5:14 PM
Chromatically Corrected Multicolor Multiphoton Microscopy
pubs.acs.org/doi/full/10....
pubs.acs.org/doi/full/10....
Happy to share that our #JOSS paper on MotilA is now published 😊
#OpenSource #Python pipeline for reproducible, batch-scale analysis of #microglia fine-process motility in 3D/4D in vivo multiphoton imaging:
📄 doi.org/10.21105/jos...
💻 github.com/FabrizioMusa...
#Neuroscience 🧪 #OpenScience
#OpenSource #Python pipeline for reproducible, batch-scale analysis of #microglia fine-process motility in 3D/4D in vivo multiphoton imaging:
📄 doi.org/10.21105/jos...
💻 github.com/FabrizioMusa...
#Neuroscience 🧪 #OpenScience
MotilA – A Python pipeline for the analysis of microglial fine process motility in 3D time-lapse multiphoton microscopy data
Musacchio et al., (2025). MotilA – A Python pipeline for the analysis of microglial fine process motility in 3D time-lapse multiphoton microscopy data. Journal of Open Source Software, 10(116), 9267, ...
doi.org
December 23, 2025 at 6:58 PM
Happy to share that our #JOSS paper on MotilA is now published 😊
#OpenSource #Python pipeline for reproducible, batch-scale analysis of #microglia fine-process motility in 3D/4D in vivo multiphoton imaging:
📄 doi.org/10.21105/jos...
💻 github.com/FabrizioMusa...
#Neuroscience 🧪 #OpenScience
#OpenSource #Python pipeline for reproducible, batch-scale analysis of #microglia fine-process motility in 3D/4D in vivo multiphoton imaging:
📄 doi.org/10.21105/jos...
💻 github.com/FabrizioMusa...
#Neuroscience 🧪 #OpenScience
This week we are @uwmadison.bsky.social for @bioimagingna.bsky.social #I2KxBINA2026. Come chat with our team about our line of microscopes from spinning disk to multiphoton to lightsheet all run by our high- #speed #accuracy #performance software SlideBook.
September 28, 2026 at 4:24 PM
This week we are @uwmadison.bsky.social for @bioimagingna.bsky.social #I2KxBINA2026. Come chat with our team about our line of microscopes from spinning disk to multiphoton to lightsheet all run by our high- #speed #accuracy #performance software SlideBook.
Fortunately, there's a resource to improve benchmarking of multiphoton systems. So things can get better. Here's the paper www.nature.com/articles/s41... And here's the free PMC version PDF (pmc.ncbi.nlm.nih.gov/articles/PMC...) (3/3)
Standardized measurements for monitoring and comparing multiphoton microscope systems - Nature Protocols
A set of procedures is described here for standardizing the evaluation of multiphoton microscope performance, covering laser power, pulse width optimizations, field of view, resolution and photomultip...
www.nature.com
January 21, 2026 at 8:55 PM
Fortunately, there's a resource to improve benchmarking of multiphoton systems. So things can get better. Here's the paper www.nature.com/articles/s41... And here's the free PMC version PDF (pmc.ncbi.nlm.nih.gov/articles/PMC...) (3/3)
We are hiring a postdoc! We study neural activity and movement using holographic optogenetics, imaging, and recordings in awake mice.
My first postdoc, Masashi, is starting his own lab, so now we have an opening.
Seeking candidates excited about circuits, optics, coding, or ephys. oldenburglab.com
My first postdoc, Masashi, is starting his own lab, so now we have an opening.
Seeking candidates excited about circuits, optics, coding, or ephys. oldenburglab.com
Oldenburg Lab
Decoding the motor system through the use of multiphoton holographic optogenetics.
oldenburglab.com
May 19, 2026 at 1:44 PM
We are hiring a postdoc! We study neural activity and movement using holographic optogenetics, imaging, and recordings in awake mice.
My first postdoc, Masashi, is starting his own lab, so now we have an opening.
Seeking candidates excited about circuits, optics, coding, or ephys. oldenburglab.com
My first postdoc, Masashi, is starting his own lab, so now we have an opening.
Seeking candidates excited about circuits, optics, coding, or ephys. oldenburglab.com
3i is hiring a Microscopist - repost & tell a friend!
Ideal candidate has experience in fundamental optical theory & familiarity with lightsheet, spinning disk, multiphoton, TIRF etc. Full-time, exempt position (travel to visit customers) offering a competitive salary & comprehensive benefits.
Ideal candidate has experience in fundamental optical theory & familiarity with lightsheet, spinning disk, multiphoton, TIRF etc. Full-time, exempt position (travel to visit customers) offering a competitive salary & comprehensive benefits.
Intelligent Imaging Innovations - Microscopist
Intelligent Imaging Innovations
intelligent-imaging.applicantstack.com
February 27, 2026 at 1:47 AM
3i is hiring a Microscopist - repost & tell a friend!
Ideal candidate has experience in fundamental optical theory & familiarity with lightsheet, spinning disk, multiphoton, TIRF etc. Full-time, exempt position (travel to visit customers) offering a competitive salary & comprehensive benefits.
Ideal candidate has experience in fundamental optical theory & familiarity with lightsheet, spinning disk, multiphoton, TIRF etc. Full-time, exempt position (travel to visit customers) offering a competitive salary & comprehensive benefits.
The two protocols are asymptotically efficient in sample complexity. We also discuss how our protocols bear on some of the previous proposals for characterizing multiphoton indistinguishability, based e.g. on the notion of genuine multiphoton indistinguishability. (4/n)
September 30, 2026 at 11:53 AM
The two protocols are asymptotically efficient in sample complexity. We also discuss how our protocols bear on some of the previous proposals for characterizing multiphoton indistinguishability, based e.g. on the notion of genuine multiphoton indistinguishability. (4/n)
🚀 Bordeaux is accelerating biological imaging! 🧬🔬
💶 €5M invested in cutting-edge tech:
🔹 MINFLUX – track single proteins at 1–2nm, >1000 loc/sec
🔹 IMPACT – next-gen multiphoton imaging in thick tissues
Bordeaux = European hub for life science innovation! 🌍✨
#BioImaging #Neuroscience
💶 €5M invested in cutting-edge tech:
🔹 MINFLUX – track single proteins at 1–2nm, >1000 loc/sec
🔹 IMPACT – next-gen multiphoton imaging in thick tissues
Bordeaux = European hub for life science innovation! 🌍✨
#BioImaging #Neuroscience
June 3, 2026 at 9:49 AM
🚀 Bordeaux is accelerating biological imaging! 🧬🔬
💶 €5M invested in cutting-edge tech:
🔹 MINFLUX – track single proteins at 1–2nm, >1000 loc/sec
🔹 IMPACT – next-gen multiphoton imaging in thick tissues
Bordeaux = European hub for life science innovation! 🌍✨
#BioImaging #Neuroscience
💶 €5M invested in cutting-edge tech:
🔹 MINFLUX – track single proteins at 1–2nm, >1000 loc/sec
🔹 IMPACT – next-gen multiphoton imaging in thick tissues
Bordeaux = European hub for life science innovation! 🌍✨
#BioImaging #Neuroscience
Multiphoton ionization at relativistic energies
August 23, 2023 at 2:27 PM
Multiphoton ionization at relativistic energies
Our Scientific Ambassador @virsicas.bsky.social interviewed Robert Lees, an expert in multiphoton & light sheet microscopy at the 🐙 Octopus facility, part of Euro-BioImaging’s UK Node @bioimaginguk.bsky.social.
🔬Learn more about his role in the full interview🔽
www.eurobioimaging.eu/news/meet-ro...
🔬Learn more about his role in the full interview🔽
www.eurobioimaging.eu/news/meet-ro...
September 9, 2025 at 2:21 PM
Our Scientific Ambassador @virsicas.bsky.social interviewed Robert Lees, an expert in multiphoton & light sheet microscopy at the 🐙 Octopus facility, part of Euro-BioImaging’s UK Node @bioimaginguk.bsky.social.
🔬Learn more about his role in the full interview🔽
www.eurobioimaging.eu/news/meet-ro...
🔬Learn more about his role in the full interview🔽
www.eurobioimaging.eu/news/meet-ro...
Fast Bosonic Control via Multiphoton Qubit-Oscillator Interactions
Read more:
https://quantum-journal.org/papers/q-2026-10-01-2224/
Read more:
https://quantum-journal.org/papers/q-2026-10-01-2224/
Fast Bosonic Control via Multiphoton Qubit-Oscillator Interactions
Noah Gorgichuk, Mohammad Ayyash, Matteo Mariantoni, and Sahel Ashhab,
Quantum 10, 2224 (2026).
We study the problem of $n$-fold rotationally symmetric bosonic state preparation, which is of great importance to bosonic quantum error correction, using a multiphoton interaction between an…
quantum-journal.org
October 1, 2026 at 1:54 PM
Fast Bosonic Control via Multiphoton Qubit-Oscillator Interactions
Read more:
https://quantum-journal.org/papers/q-2026-10-01-2224/
Read more:
https://quantum-journal.org/papers/q-2026-10-01-2224/