#NephJC and @theisn.org Advancing Clinical Trials collab for #Nephtrials
STEPS trial tests coordinated system-level intervention to improve preemptive kidney transplant
🗓️XSpce: April 10, 12pm EST
✍️Blog by @dramiliflores.bsky.social and @nephroseeker.medsky.social
www.nephjc.com/news/steps-n...
STEPS trial tests coordinated system-level intervention to improve preemptive kidney transplant
🗓️XSpce: April 10, 12pm EST
✍️Blog by @dramiliflores.bsky.social and @nephroseeker.medsky.social
www.nephjc.com/news/steps-n...
From missed opportunities to equitable access: Can STEPS redesign the kidney transplant pathway? — NephJC
Summary of the STEPS trial which will be a twitter spaces discussion
www.nephjc.com
April 9, 2026 at 10:08 PM
𝗧𝗢𝗗𝗔𝗬: Join us & @nephjc.bsky.social for #NephTrials as we discuss CAPTIVATE.
🗣️ Sradha Kotwal, @hswapnil.medsky.social, @kidneyboy.bsky.social, @dilushiwijay.bsky.social Manjusha Yadla
🕘 9 pm EST
Join: twitter.com/i/spaces/1gq...
Read: www.nephjc.com/news/nephtrials-captivate
🗣️ Sradha Kotwal, @hswapnil.medsky.social, @kidneyboy.bsky.social, @dilushiwijay.bsky.social Manjusha Yadla
🕘 9 pm EST
Join: twitter.com/i/spaces/1gq...
Read: www.nephjc.com/news/nephtrials-captivate
Scheduled: Nephtrials - CAPTIVATE: Finding treatments to slow the CKD progression
Int Society of Nephrology’s Space · Where live audio conversations happen
twitter.com
June 25, 2025 at 5:35 PM
𝗧𝗢𝗗𝗔𝗬: Join us & @nephjc.bsky.social for #NephTrials as we discuss CAPTIVATE.
🗣️ Sradha Kotwal, @hswapnil.medsky.social, @kidneyboy.bsky.social, @dilushiwijay.bsky.social Manjusha Yadla
🕘 9 pm EST
Join: twitter.com/i/spaces/1gq...
Read: www.nephjc.com/news/nephtrials-captivate
🗣️ Sradha Kotwal, @hswapnil.medsky.social, @kidneyboy.bsky.social, @dilushiwijay.bsky.social Manjusha Yadla
🕘 9 pm EST
Join: twitter.com/i/spaces/1gq...
Read: www.nephjc.com/news/nephtrials-captivate
Feed: "Blog - NephJC"
By: Cristina Adriana Popa on Monday, June 30, 2025
By: Cristina Adriana Popa on Monday, June 30, 2025
CAPTIVATE NephTrials Visual Abstract
Check out the beautiful visual abstract made by Kajaree Giri
www.nephjc.com
June 30, 2025 at 8:03 PM
Feed: "Blog - NephJC"
By: Cristina Adriana Popa on Monday, June 30, 2025
By: Cristina Adriana Popa on Monday, June 30, 2025
Feed: "Blog - NephJC"
By: swapnil hiremath on Wednesday, June 25, 2025
By: swapnil hiremath on Wednesday, June 25, 2025
From single shots to strategy: How CAPTIVATE is reframing the NephTrials playbook
Summary of the CAPTIVATE platform which will be a twitter spaces discussion
www.nephjc.com
June 25, 2025 at 8:02 PM
Feed: "Blog - NephJC"
By: swapnil hiremath on Wednesday, June 25, 2025
By: swapnil hiremath on Wednesday, June 25, 2025
Yes Twitter is a dumpster fire but it has a technology of audio spaces that we cannot recreate on Bluesky so dust off the ol' twitter account and join the @nephjc.bsky.social and the ISN for a discussion on the CAPTIVATE research platform at 9pm tonight
x.com/i/spaces/1gq...
x.com/i/spaces/1gq...
Scheduled: Nephtrials - CAPTIVATE: Finding treatments to slow the CKD progression
Int Society of Nephrology’s Space · Where live audio conversations happen
x.com
June 26, 2025 at 12:55 AM
Yes Twitter is a dumpster fire but it has a technology of audio spaces that we cannot recreate on Bluesky so dust off the ol' twitter account and join the @nephjc.bsky.social and the ISN for a discussion on the CAPTIVATE research platform at 9pm tonight
x.com/i/spaces/1gq...
x.com/i/spaces/1gq...
Joel Topf, #NephTrials. I'm a pragmatic guy but I don't know what a pragmatic trial is.
December 1, 2024 at 10:13 AM
Joel Topf, #NephTrials. I'm a pragmatic guy but I don't know what a pragmatic trial is.
Worry that pragmatic trial may miss small benefits that get swallowed by heterogeneity in execution of intervention. (Am I thinking about this right?) #NephTrials
December 1, 2024 at 10:13 AM
Worry that pragmatic trial may miss small benefits that get swallowed by heterogeneity in execution of intervention. (Am I thinking about this right?) #NephTrials
Acetaminophen would score high on QoL for influenza but no one calls it a therapy for influenza. #nephTrials
December 1, 2024 at 10:13 AM
Acetaminophen would score high on QoL for influenza but no one calls it a therapy for influenza. #nephTrials
Back from the dog walk. Tready to dig in to #NephTrials
December 1, 2024 at 5:31 AM
Back from the dog walk. Tready to dig in to #NephTrials
What are the primary compromises that had to be made to the protocol because of using the registry? #NephTrials
November 26, 2024 at 10:08 PM
What are the primary compromises that had to be made to the protocol because of using the registry? #NephTrials
If we get clear and convincing evidence that HDF leads to better survival we will need to apply maximum pressure to Davita, Fresenius, and the US Government to make it widely available in the US. #NephTrials
November 26, 2024 at 10:08 PM
If we get clear and convincing evidence that HDF leads to better survival we will need to apply maximum pressure to Davita, Fresenius, and the US Government to make it widely available in the US. #NephTrials
Just getting set up here. Sorry I'm late. #NephTrials
November 25, 2024 at 7:22 AM
Just getting set up here. Sorry I'm late. #NephTrials
The numbers: 280 Tweets. 34 Participants. 3,125,321 Impressions. March 9th 2023. More #NephTrials 📊 here https://www.symplur.com/healthcare-hashtags/NephTrials/analytics/?hashtag=NephTrials&fdate=3%2F9%2F2023&shour=7&smin=0&tdate=3%2F10%2F2023&thour=7&tmin=0 via @symplur
November 25, 2024 at 7:22 AM
The numbers: 280 Tweets. 34 Participants. 3,125,321 Impressions. March 9th 2023. More #NephTrials 📊 here https://www.symplur.com/healthcare-hashtags/NephTrials/analytics/?hashtag=NephTrials&fdate=3%2F9%2F2023&shour=7&smin=0&tdate=3%2F10%2F2023&thour=7&tmin=0 via @symplur
Joel Topf, community nephrologust abnd #NephJC co-founder ready to pretend I know something about clinical trial design as part of #NephTrials
November 24, 2024 at 8:07 PM
Joel Topf, community nephrologust abnd #NephJC co-founder ready to pretend I know something about clinical trial design as part of #NephTrials
According to @fperrywilson's How Medicine Works and When it Doesn't, there are only three outcomes that really matter:
1. Death
2. Birth
3. Quality of life
#NephJCBookClub
#NephTrials
1. Death
2. Birth
3. Quality of life
#NephJCBookClub
#NephTrials
November 24, 2024 at 8:00 PM
According to @fperrywilson's How Medicine Works and When it Doesn't, there are only three outcomes that really matter:
1. Death
2. Birth
3. Quality of life
#NephJCBookClub
#NephTrials
1. Death
2. Birth
3. Quality of life
#NephJCBookClub
#NephTrials
I'm going to work on my own QoL by going for a run. #NephTrials thanks for the education
November 24, 2024 at 8:00 PM
I'm going to work on my own QoL by going for a run. #NephTrials thanks for the education
Time to plug in your AirPods and join the #Nephtrials Space. We are trying something different with Twitter. Let's go into live audio! https://x.com/i/spaces/1YqKDgDLgeNxV
x.com
x.com
November 24, 2024 at 2:48 AM
Time to plug in your AirPods and join the #Nephtrials Space. We are trying something different with Twitter. Let's go into live audio! https://x.com/i/spaces/1YqKDgDLgeNxV
N of 1 trials
Basket Trials multiple diseases same intervention
Umbrella trials same disease, different intervention
Platform trial: multiple interventions modified over time as data is accumulated.
#NephTrials
#KidneyWk
Basket Trials multiple diseases same intervention
Umbrella trials same disease, different intervention
Platform trial: multiple interventions modified over time as data is accumulated.
#NephTrials
#KidneyWk
November 23, 2024 at 11:54 AM
N of 1 trials
Basket Trials multiple diseases same intervention
Umbrella trials same disease, different intervention
Platform trial: multiple interventions modified over time as data is accumulated.
#NephTrials
#KidneyWk
Basket Trials multiple diseases same intervention
Umbrella trials same disease, different intervention
Platform trial: multiple interventions modified over time as data is accumulated.
#NephTrials
#KidneyWk
A side point: classic RCTs in dialysis have problems with enrollment- RENAL AF, AXADIA-AFNET 8- even CONVINCE Maybe the solution is to design master trial protocols?- which cut costs, solve some of the generalizability issues (e.g. geographical distributions) #nephjc www.nephjc.com/news/master-...
NephTrials: Basket Trials, Umbrella Trials, and the RENAL LIFECYCLE trial — NephJC
master trials
umbrella trials
platform trials
basket trials
RCT methodology
flozins
SGLT2 inhibitors
NephTrials
RENAL LIFECYCLE
Dapagliflozin
www.nephjc.com
November 20, 2024 at 4:36 AM
A side point: classic RCTs in dialysis have problems with enrollment- RENAL AF, AXADIA-AFNET 8- even CONVINCE Maybe the solution is to design master trial protocols?- which cut costs, solve some of the generalizability issues (e.g. geographical distributions) #nephjc www.nephjc.com/news/master-...
<a href="http://www.nephjc.com/news/2022/9/19/nephtrials-registry" class="hover:underline text-blue-600 dark:text-sky-400 no-card-link" target="_blank" rel="noopener" data-link="bsky">http://www.nephjc.com/news/2022/9/19/nephtrials-registry
Efficiency in clinical trials: Getting to the H4RT of re...
The next #Nephtrials discussion will feature a deep dive ...
www.nephjc.com
November 17, 2024 at 1:18 PM
<a href="http://www.nephjc.com/news/2022/9/19/nephtrials-registry" class="hover:underline text-blue-600 dark:text-sky-400 no-card-link" target="_blank" rel="noopener" data-link="bsky">http://www.nephjc.com/news/2022/9/19/nephtrials-registry
And predictions from @SRNefro and @accovic, CONVINCE trial will be negative (because it included older people with high comorbidities), but most probably it will have a positive subgroup analysis
For more details see #NephTrials discussions...
For more details see #NephTrials discussions...
November 17, 2024 at 12:37 PM
And predictions from @SRNefro and @accovic, CONVINCE trial will be negative (because it included older people with high comorbidities), but most probably it will have a positive subgroup analysis
For more details see #NephTrials discussions...
For more details see #NephTrials discussions...
Hi! Cristina Popa, Romanian nephrologist, lurking from dialysis shift, where I might have patients on HD or HDF. No COIs #Nephtrial #NephJc #Nephtrials
November 17, 2024 at 10:57 AM
Hi! Cristina Popa, Romanian nephrologist, lurking from dialysis shift, where I might have patients on HD or HDF. No COIs #Nephtrial #NephJc #Nephtrials
Hi! Cristina Popa here, Romanian nephrologist. On call, with a basket of CKDs in ED. 🚨 Hopefully I will be lurking 🤞#Nephtrials #NephJc
November 17, 2024 at 5:29 AM
Hi! Cristina Popa here, Romanian nephrologist. On call, with a basket of CKDs in ED. 🚨 Hopefully I will be lurking 🤞#Nephtrials #NephJc
Hi! I'm Cristina Popa, Romanian nephrologist fighting against my every instinct to not fall asleep (4 am& unmeasurable sleep in the last 72 h) #NephTrials
The essence: what would my pts would choose? The scientific illusion of a hard endpoint or reality of a little better QoL?
The essence: what would my pts would choose? The scientific illusion of a hard endpoint or reality of a little better QoL?
November 17, 2024 at 4:13 AM
Hi! I'm Cristina Popa, Romanian nephrologist fighting against my every instinct to not fall asleep (4 am& unmeasurable sleep in the last 72 h) #NephTrials
The essence: what would my pts would choose? The scientific illusion of a hard endpoint or reality of a little better QoL?
The essence: what would my pts would choose? The scientific illusion of a hard endpoint or reality of a little better QoL?