Nature research paper: Wake-activated neuronal populations that regulate sleep drive
go.nature.com/4qsYiYU
go.nature.com/4qsYiYU
Wake-activated neuronal populations that regulate sleep drive - Nature
Whole-brain activity mapping, targeted cell manipulations and electrophysiology in mice identify wake-activated neuronal populations that are crucial for sleep drive and can persistently reduce daily sleep amount.
go.nature.com
August 25, 2026 at 8:18 AM
Nature research paper: Wake-activated neuronal populations that regulate sleep drive
go.nature.com/4qsYiYU
go.nature.com/4qsYiYU
What regulates the urge to sleep? William Joo and colleagues identified brain regions that reflect how long mice have been awake. Strikingly, inhibiting one of these regions reduces sleep by 70%, without the major behavioral deficits associated with sleep deprivation. www.nature.com/articles/s41...
Wake-activated neuronal populations that regulate sleep drive - Nature
Whole-brain activity mapping, targeted cell manipulations and electrophysiology in mice identify wake-activated neuronal populations that are crucial for sleep drive and can persistently red...
www.nature.com
August 19, 2026 at 3:41 PM
What regulates the urge to sleep? William Joo and colleagues identified brain regions that reflect how long mice have been awake. Strikingly, inhibiting one of these regions reduces sleep by 70%, without the major behavioral deficits associated with sleep deprivation. www.nature.com/articles/s41...
Nature research paper: Mapping the neuronal building blocks of human language with language models
go.nature.com/4a9Xl0E
go.nature.com/4a9Xl0E
Mapping the neuronal building blocks of human language with language models - Nature
Wide-scale recordings reveal neurons in the human brain that encode fundamental components of language such as the grammatical relationships between words, their parts of speech and the higher-order syntactic structure of phrases and sentences.
go.nature.com
June 23, 2026 at 8:02 AM
Nature research paper: Mapping the neuronal building blocks of human language with language models
go.nature.com/4a9Xl0E
go.nature.com/4a9Xl0E
happy to share our new protocol paper on wildDISCO for whole-body immunolabeling, tissue clearing & 3D imaging of intact mice at cellular resolution using standard IgG antibodies, for mapping of neuronal, vascular, lymphatic and immune systems across the entire body.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
May 13, 2026 at 7:40 AM
happy to share our new protocol paper on wildDISCO for whole-body immunolabeling, tissue clearing & 3D imaging of intact mice at cellular resolution using standard IgG antibodies, for mapping of neuronal, vascular, lymphatic and immune systems across the entire body.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
How animals detect the Earth’s magnetic field remains a mystery in sensory biology.
In Science, researchers used whole brain activity mapping, tissue clearing, and light sheet microscopy to identify neuronal populations activated by magnetic stimuli in the pigeon. https://scim.ag/48szWXT
In Science, researchers used whole brain activity mapping, tissue clearing, and light sheet microscopy to identify neuronal populations activated by magnetic stimuli in the pigeon. https://scim.ag/48szWXT
A global screen for magnetically induced neuronal activity in the pigeon brain
How animals detect the Earth’s magnetic field remains a mystery in sensory biology. Despite extensive behavioral evidence, the neural circuitry and molecular mechanisms responsible for magnetic sensin...
scim.ag
December 11, 2025 at 10:06 PM
How animals detect the Earth’s magnetic field remains a mystery in sensory biology.
In Science, researchers used whole brain activity mapping, tissue clearing, and light sheet microscopy to identify neuronal populations activated by magnetic stimuli in the pigeon. https://scim.ag/48szWXT
In Science, researchers used whole brain activity mapping, tissue clearing, and light sheet microscopy to identify neuronal populations activated by magnetic stimuli in the pigeon. https://scim.ag/48szWXT
Reconstructing long-range axons from dense brain images is tough.
This study introduces a novel method that separates axon identification from global statistical rules, showing big improvements over existing tools for mapping neuronal projections.
buff.ly/OBKr9cM
This study introduces a novel method that separates axon identification from global statistical rules, showing big improvements over existing tools for mapping neuronal projections.
buff.ly/OBKr9cM
September 7, 2025 at 10:01 AM
Reconstructing long-range axons from dense brain images is tough.
This study introduces a novel method that separates axon identification from global statistical rules, showing big improvements over existing tools for mapping neuronal projections.
buff.ly/OBKr9cM
This study introduces a novel method that separates axon identification from global statistical rules, showing big improvements over existing tools for mapping neuronal projections.
buff.ly/OBKr9cM
Holy shit, nerds, have you seen this? If you're studying #brain wide neuronal activation using #cFOS and a #lightsheet #microscope you need to read this doc STAT🧪🔬.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
A deep learning pipeline for three-dimensional brain-wide mapping of local neuronal ensembles in teravoxel light-sheet microscopy - Nature Methods
The ACE pipeline utilized deep learning and advanced statistics for mapping neural activity at a granular level that is independent of atlas-defined regions.
www.nature.com
January 30, 2025 at 12:52 AM
Holy shit, nerds, have you seen this? If you're studying #brain wide neuronal activation using #cFOS and a #lightsheet #microscope you need to read this doc STAT🧪🔬.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reconstructing long-range axons from dense brain images is tough.
This study introduces a novel method that separates axon identification from global statistical rules, showing big improvements over existing tools for mapping neuronal projections.
buff.ly/o7QmH4B
This study introduces a novel method that separates axon identification from global statistical rules, showing big improvements over existing tools for mapping neuronal projections.
buff.ly/o7QmH4B
September 19, 2025 at 8:21 AM
Reconstructing long-range axons from dense brain images is tough.
This study introduces a novel method that separates axon identification from global statistical rules, showing big improvements over existing tools for mapping neuronal projections.
buff.ly/o7QmH4B
This study introduces a novel method that separates axon identification from global statistical rules, showing big improvements over existing tools for mapping neuronal projections.
buff.ly/o7QmH4B
Researchers have created the largest and most detailed wiring diagram of a mammalian brain to date, by mapping cells in a cubic millimetre of a mouse’s brain tissue
https://go.nature.com/4cu68dN
https://go.nature.com/4cu68dN
Biggest brain map ever details huge number of neurons and their activity
3D reconstruction is the first to overlay neuronal activity on a large-scale map of brain cells.
go.nature.com
April 9, 2025 at 4:36 PM
Researchers have created the largest and most detailed wiring diagram of a mammalian brain to date, by mapping cells in a cubic millimetre of a mouse’s brain tissue
https://go.nature.com/4cu68dN
https://go.nature.com/4cu68dN
A new method called VIPS enables organ-wide nanoscale reconstruction for quantitative mapping of connectivity and molecular landscape in intact tissue.
Learn more this week in Science: https://scim.ag/4n4GKPm
Learn more this week in Science: https://scim.ag/4n4GKPm
October 16, 2025 at 6:05 PM
A new method called VIPS enables organ-wide nanoscale reconstruction for quantitative mapping of connectivity and molecular landscape in intact tissue.
Learn more this week in Science: https://scim.ag/4n4GKPm
Learn more this week in Science: https://scim.ag/4n4GKPm
A new genetic toolkit lets researchers target most neuronal lineages in the #Drosophila ventral nerve cord across development and into adulthood, opening the door to mapping structure, chemistry, and behaviour.
buff.ly/zHQK9dC
buff.ly/zHQK9dC
July 5, 2025 at 4:28 PM
A new genetic toolkit lets researchers target most neuronal lineages in the #Drosophila ventral nerve cord across development and into adulthood, opening the door to mapping structure, chemistry, and behaviour.
buff.ly/zHQK9dC
buff.ly/zHQK9dC
Connectome-seq: High-throughput Mapping of Neuronal Connectivity at Single-Synapse Resolution via Barcode Sequencing https://www.biorxiv.org/content/10.1101/2025.02.13.638129v1
February 15, 2025 at 7:15 AM
Connectome-seq: High-throughput Mapping of Neuronal Connectivity at Single-Synapse Resolution via Barcode Sequencing https://www.biorxiv.org/content/10.1101/2025.02.13.638129v1
What drives cytoplasmic mRNA organization? We created unbiased, genome-wide maps of mesoscale RNA-RNA spatial proximity, revealing impact of encoded protein function. Fantastic work from @lindsayabecker.bsky.social @sofiquinodoz.bsky.social @davidaknowles.bsky.social www.biorxiv.org/content/10.1...
Genome-wide mapping of mesoscale neuronal RNA organization and condensation
Subcellular RNA organization can affect critical cellular functions. However, our understanding of RNA microenvironments, particularly biomolecular condensates, remains limited, largely due to a lack ...
www.biorxiv.org
April 21, 2025 at 1:48 PM
What drives cytoplasmic mRNA organization? We created unbiased, genome-wide maps of mesoscale RNA-RNA spatial proximity, revealing impact of encoded protein function. Fantastic work from @lindsayabecker.bsky.social @sofiquinodoz.bsky.social @davidaknowles.bsky.social www.biorxiv.org/content/10.1...
A study published in Nature identifies distinct neuronal populations in the frontotemporal cortex that capture both syntactic and semantic properties of language. These neurons dynamically incorporate sentence context, enhancing our understanding of language processing. 🧪 #Neuroscience
Mapping the neuronal building blocks of human language with language models - Nature
Wide-scale recordings reveal neurons in the human brain that encode fundamental components of language such as the grammatical relationships between words, their parts of speech and the higher-order syntactic structure of phrases and sentences.
go.nature.com
July 13, 2026 at 1:48 AM
A study published in Nature identifies distinct neuronal populations in the frontotemporal cortex that capture both syntactic and semantic properties of language. These neurons dynamically incorporate sentence context, enhancing our understanding of language processing. 🧪 #Neuroscience
Mapping neurons in the brain of a beetle, by Gregor Bucher's team @bucherlab.bsky.social
www.biorxiv.org/content/10.6...
Happy we could make a minor contribution by providing a Brainbow construct, which the team used to map neuronal projections
Tribolium Brainbow soon available on Addgene
www.biorxiv.org/content/10.6...
Happy we could make a minor contribution by providing a Brainbow construct, which the team used to map neuronal projections
Tribolium Brainbow soon available on Addgene
May 14, 2026 at 5:13 PM
Mapping neurons in the brain of a beetle, by Gregor Bucher's team @bucherlab.bsky.social
www.biorxiv.org/content/10.6...
Happy we could make a minor contribution by providing a Brainbow construct, which the team used to map neuronal projections
Tribolium Brainbow soon available on Addgene
www.biorxiv.org/content/10.6...
Happy we could make a minor contribution by providing a Brainbow construct, which the team used to map neuronal projections
Tribolium Brainbow soon available on Addgene
How animals detect the Earth’s magnetic field remains a mystery in sensory biology. In a new Science study, researchers used whole brain activity mapping, tissue clearing, and light sheet microscopy to identify neuronal populations activated by magnetic stimuli in the pigeon.
A global screen for magnetically induced neuronal activity in the pigeon brain
How animals detect the Earth’s magnetic field remains a mystery in sensory biology. Despite extensive behavioral evidence, the neural circuitry and molecular mechanisms responsible for magnetic sensin...
www.science.org
December 21, 2025 at 7:28 PM
How animals detect the Earth’s magnetic field remains a mystery in sensory biology. In a new Science study, researchers used whole brain activity mapping, tissue clearing, and light sheet microscopy to identify neuronal populations activated by magnetic stimuli in the pigeon.
Now online! Brain-wide mapping of immune receptors uncovers a neuromodulatory role of IL-17E and the receptor IL-17RB
Brain-wide mapping of immune receptors uncovers a neuromodulatory role of IL-17E and the receptor IL-17RB
Mapping the expression of all five IL-17 receptor subunits in the mouse brain reveals how IL-17 cytokines shape social behaviors by modulating neuronal activity within the somatosensory cortex.
dlvr.it
April 7, 2025 at 10:39 PM
Now online! Brain-wide mapping of immune receptors uncovers a neuromodulatory role of IL-17E and the receptor IL-17RB
Reconstructing long-range axons from dense brain images is tough.
This study introduces a novel method that separates axon identification from global statistical rules, showing big improvements over existing tools for mapping neuronal projections.
buff.ly/6ajguDI
This study introduces a novel method that separates axon identification from global statistical rules, showing big improvements over existing tools for mapping neuronal projections.
buff.ly/6ajguDI
September 12, 2025 at 1:59 PM
Reconstructing long-range axons from dense brain images is tough.
This study introduces a novel method that separates axon identification from global statistical rules, showing big improvements over existing tools for mapping neuronal projections.
buff.ly/6ajguDI
This study introduces a novel method that separates axon identification from global statistical rules, showing big improvements over existing tools for mapping neuronal projections.
buff.ly/6ajguDI
A study published in Nature identifies distinct neuronal populations in the frontotemporal cortex that capture both syntactic and semantic properties of language. These neurons dynamically incorporate sentence context, enhancing our understanding of language processing. 🧪 #Neuroscience
Mapping the neuronal building blocks of human language with language models - Nature
Wide-scale recordings reveal neurons in the human brain that encode fundamental components of language such as the grammatical relationships between words, their parts of speech and the higher-order syntactic structure of phrases and sentences.
go.nature.com
July 5, 2026 at 4:00 PM
A study published in Nature identifies distinct neuronal populations in the frontotemporal cortex that capture both syntactic and semantic properties of language. These neurons dynamically incorporate sentence context, enhancing our understanding of language processing. 🧪 #Neuroscience
Researchers recorded from single neurons across frontotemporal cortex in 8 awake individuals during natural speech. They show how activities of collections of cells can capture syntactic & semantic properties of words, & also dynamically incorporate sentence context to encode combinatorial info.
🗣️🧠🧪
🗣️🧠🧪
Mapping the neuronal building blocks of human language with language models - Nature
Wide-scale recordings reveal neurons in the human brain that encode fundamental components of language such as the grammatical relationships between words, their parts of speech and the...
www.nature.com
June 18, 2026 at 10:58 AM
Researchers recorded from single neurons across frontotemporal cortex in 8 awake individuals during natural speech. They show how activities of collections of cells can capture syntactic & semantic properties of words, & also dynamically incorporate sentence context to encode combinatorial info.
🗣️🧠🧪
🗣️🧠🧪
A central finding is that the mapping from circuit structure to neural manifold dynamics is degenerate (so distinct circuit topologies can produce equivalent latent dynamics) but that circuit structure nonetheless constrains the topology of neuronal embeddings in the similarity space.
March 8, 2026 at 5:28 PM
A central finding is that the mapping from circuit structure to neural manifold dynamics is degenerate (so distinct circuit topologies can produce equivalent latent dynamics) but that circuit structure nonetheless constrains the topology of neuronal embeddings in the similarity space.
🚨NEW EPISODE🚨
How do we map the #brain at molecular resolution?
@sventruckenbrodt.bsky.social Dr. Sven Truckenbrodt explains #connectomics, #expansion microscopy, neuronal barcoding, and why scaling brain mapping is still a major challenge.
🔗Link to the video: youtu.be/a4qpFpjnOX4
How do we map the #brain at molecular resolution?
@sventruckenbrodt.bsky.social Dr. Sven Truckenbrodt explains #connectomics, #expansion microscopy, neuronal barcoding, and why scaling brain mapping is still a major challenge.
🔗Link to the video: youtu.be/a4qpFpjnOX4
February 23, 2026 at 5:03 PM
🚨NEW EPISODE🚨
How do we map the #brain at molecular resolution?
@sventruckenbrodt.bsky.social Dr. Sven Truckenbrodt explains #connectomics, #expansion microscopy, neuronal barcoding, and why scaling brain mapping is still a major challenge.
🔗Link to the video: youtu.be/a4qpFpjnOX4
How do we map the #brain at molecular resolution?
@sventruckenbrodt.bsky.social Dr. Sven Truckenbrodt explains #connectomics, #expansion microscopy, neuronal barcoding, and why scaling brain mapping is still a major challenge.
🔗Link to the video: youtu.be/a4qpFpjnOX4
What happens in the frontotemporal cortex during language production?
Turns out distinct neurons represent detailed grammatical relationships between words & others track the sentences’ higher-order syntactic structure, phrase transitions & sequence
@nature.com 🧪
www.nature.com/articles/s41...
Turns out distinct neurons represent detailed grammatical relationships between words & others track the sentences’ higher-order syntactic structure, phrase transitions & sequence
@nature.com 🧪
www.nature.com/articles/s41...
Mapping the neuronal building blocks of human language with language models - Nature
Wide-scale recordings reveal neurons in the human brain that encode fundamental components of language such as the grammatical relationships between words, their parts of speech and the...
www.nature.com
June 18, 2026 at 7:11 AM
What happens in the frontotemporal cortex during language production?
Turns out distinct neurons represent detailed grammatical relationships between words & others track the sentences’ higher-order syntactic structure, phrase transitions & sequence
@nature.com 🧪
www.nature.com/articles/s41...
Turns out distinct neurons represent detailed grammatical relationships between words & others track the sentences’ higher-order syntactic structure, phrase transitions & sequence
@nature.com 🧪
www.nature.com/articles/s41...
In a new study in @cp-neuron.bksy.social we demonstrate how sparse genetic labeling enables comprehensive reconstruction of individual dopamine neurons in mice; Subtypes exhibit distinct developmental and adult morphologies, as well as responses to axon degeneration. www.cell.com/neuron/fullt...
Single-neuron resolution mapping of dopaminergic connectivity across development, adulthood, and degeneration
Using a novel intersectional genetic strategy for sparse neuronal labeling, Grossouw,
Heijmink, et al. reconstruct individual midbrain dopamine neurons throughout development,
adulthood, and degenerat...
www.cell.com
August 8, 2026 at 7:44 AM
In a new study in @cp-neuron.bksy.social we demonstrate how sparse genetic labeling enables comprehensive reconstruction of individual dopamine neurons in mice; Subtypes exhibit distinct developmental and adult morphologies, as well as responses to axon degeneration. www.cell.com/neuron/fullt...