Wyoming H5N1 bird flu case uploads to GISAID
—PB2 E627K mutation detected
Partial sequence from a Wyoming patient confirms H5N1 D1.1 genotype with PB2 E627K
It’s a key adaptation for mammalian replication.
—PB2 E627K mutation detected
Partial sequence from a Wyoming patient confirms H5N1 D1.1 genotype with PB2 E627K
It’s a key adaptation for mammalian replication.
February 26, 2025 at 2:10 PM
Wyoming H5N1 bird flu case uploads to GISAID
—PB2 E627K mutation detected
Partial sequence from a Wyoming patient confirms H5N1 D1.1 genotype with PB2 E627K
It’s a key adaptation for mammalian replication.
—PB2 E627K mutation detected
Partial sequence from a Wyoming patient confirms H5N1 D1.1 genotype with PB2 E627K
It’s a key adaptation for mammalian replication.
NEVADA DAIRY WORKER WITH BIRD FLU HAS...
PB2 D701N per @cbarbermd at X
attributed to @CDCgov
#H5N1 PB2 D701N had been detected in cows from the first four tested herds in Churchill Co NV
Additional conf Dairy workers linked to these 4 farms and 2 new farms also expected to be D701N pos
PB2 D701N per @cbarbermd at X
attributed to @CDCgov
#H5N1 PB2 D701N had been detected in cows from the first four tested herds in Churchill Co NV
Additional conf Dairy workers linked to these 4 farms and 2 new farms also expected to be D701N pos
February 11, 2025 at 1:02 AM
NEVADA DAIRY WORKER WITH BIRD FLU HAS...
PB2 D701N per @cbarbermd at X
attributed to @CDCgov
#H5N1 PB2 D701N had been detected in cows from the first four tested herds in Churchill Co NV
Additional conf Dairy workers linked to these 4 farms and 2 new farms also expected to be D701N pos
PB2 D701N per @cbarbermd at X
attributed to @CDCgov
#H5N1 PB2 D701N had been detected in cows from the first four tested herds in Churchill Co NV
Additional conf Dairy workers linked to these 4 farms and 2 new farms also expected to be D701N pos
BN + PB2 = TD
September 28, 2026 at 2:27 AM
BN + PB2 = TD
Acaì bowl with PB2 and protein powder 🤤
March 18, 2026 at 1:49 AM
Acaì bowl with PB2 and protein powder 🤤
PB2 watching SGA film in the offseason
September 28, 2026 at 3:36 AM
PB2 watching SGA film in the offseason
PB2 (two different brands of peanut butter sandwich) sounds delicious
September 28, 2026 at 3:30 AM
PB2 (two different brands of peanut butter sandwich) sounds delicious
BREAKING: VIRUS FROM NEVADA DAIRY WORKER WITH BIRD FLU HAS THE SAME GENETIC MUTATION seen in the Nevada cows – a change of PB2 D701N that has previously been assoc with more efficient virus replication in ppl & mammals.
CDC told Fortune that the D1.1 variant in this worker is the same strain of
CDC told Fortune that the D1.1 variant in this worker is the same strain of
February 11, 2025 at 12:12 AM
BREAKING: VIRUS FROM NEVADA DAIRY WORKER WITH BIRD FLU HAS THE SAME GENETIC MUTATION seen in the Nevada cows – a change of PB2 D701N that has previously been assoc with more efficient virus replication in ppl & mammals.
CDC told Fortune that the D1.1 variant in this worker is the same strain of
CDC told Fortune that the D1.1 variant in this worker is the same strain of
4) The adaptations seen (like PB2-E627K in the dairy worker strain, PB2-T271A in polecat strain) may enable higher replication, allowing some air shedding despite the virus still preferring avian-type receptors. But efficiency remains much lower than human flu viruses. (At this time)
December 3, 2024 at 8:44 PM
4) The adaptations seen (like PB2-E627K in the dairy worker strain, PB2-T271A in polecat strain) may enable higher replication, allowing some air shedding despite the virus still preferring avian-type receptors. But efficiency remains much lower than human flu viruses. (At this time)
one of the most bizarre products i've ever seen
March 2, 2026 at 9:46 PM
one of the most bizarre products i've ever seen
1/7 🚨BIRD FLU MUTATION ALERT🚨
Scientists have identified a concerning genetic mutation in H5N1 bird flu from dairy cows in San Bernardino County.
The mutation, called PB2 E627K, could make the virus more deadly and transmissible between mammals.
#BirdFlu #PublicHealth
#H5N1 #BirdFlu
Scientists have identified a concerning genetic mutation in H5N1 bird flu from dairy cows in San Bernardino County.
The mutation, called PB2 E627K, could make the virus more deadly and transmissible between mammals.
#BirdFlu #PublicHealth
#H5N1 #BirdFlu
March 13, 2025 at 9:05 PM
1/7 🚨BIRD FLU MUTATION ALERT🚨
Scientists have identified a concerning genetic mutation in H5N1 bird flu from dairy cows in San Bernardino County.
The mutation, called PB2 E627K, could make the virus more deadly and transmissible between mammals.
#BirdFlu #PublicHealth
#H5N1 #BirdFlu
Scientists have identified a concerning genetic mutation in H5N1 bird flu from dairy cows in San Bernardino County.
The mutation, called PB2 E627K, could make the virus more deadly and transmissible between mammals.
#BirdFlu #PublicHealth
#H5N1 #BirdFlu
H5N1 shows the 1918 flu's PB2 E627K mutation and D190E, which shifts the virus to human receptors.
These mutations increase human infection risk, and with recent mammalian outbreaks, raise concerns about potential human-to-human spread.
These mutations increase human infection risk, and with recent mammalian outbreaks, raise concerns about potential human-to-human spread.
November 20, 2024 at 4:41 AM
H5N1 shows the 1918 flu's PB2 E627K mutation and D190E, which shifts the virus to human receptors.
These mutations increase human infection risk, and with recent mammalian outbreaks, raise concerns about potential human-to-human spread.
These mutations increase human infection risk, and with recent mammalian outbreaks, raise concerns about potential human-to-human spread.
⚠️ BREAKING:
Dangerous Bird Flu Strain in British Columbia Teen Linked to 1918 Spanish Flu Pandemic
D1.1 Bird Flu in BC Teen has HA: E190D and PB2: E627K mutations, same as the 1918 Spanish Flu that killed millions.
Dangerous Bird Flu Strain in British Columbia Teen Linked to 1918 Spanish Flu Pandemic
D1.1 Bird Flu in BC Teen has HA: E190D and PB2: E627K mutations, same as the 1918 Spanish Flu that killed millions.
November 20, 2024 at 5:07 AM
⚠️ BREAKING:
Dangerous Bird Flu Strain in British Columbia Teen Linked to 1918 Spanish Flu Pandemic
D1.1 Bird Flu in BC Teen has HA: E190D and PB2: E627K mutations, same as the 1918 Spanish Flu that killed millions.
Dangerous Bird Flu Strain in British Columbia Teen Linked to 1918 Spanish Flu Pandemic
D1.1 Bird Flu in BC Teen has HA: E190D and PB2: E627K mutations, same as the 1918 Spanish Flu that killed millions.
H5N1 Bird Flu is a
About to Go Global.
The D1.1 strain in Nevada, with the PB2 D701N mutation, is spreading faster in dairy herds than the B3.13 strain.
Migrating birds will carry it worldwide, raising the risk of mammalian outbreaks.
This is no longer just a U.S. issue it’s a global threat.
About to Go Global.
The D1.1 strain in Nevada, with the PB2 D701N mutation, is spreading faster in dairy herds than the B3.13 strain.
Migrating birds will carry it worldwide, raising the risk of mammalian outbreaks.
This is no longer just a U.S. issue it’s a global threat.
February 9, 2025 at 1:41 AM
H5N1 Bird Flu is a
About to Go Global.
The D1.1 strain in Nevada, with the PB2 D701N mutation, is spreading faster in dairy herds than the B3.13 strain.
Migrating birds will carry it worldwide, raising the risk of mammalian outbreaks.
This is no longer just a U.S. issue it’s a global threat.
About to Go Global.
The D1.1 strain in Nevada, with the PB2 D701N mutation, is spreading faster in dairy herds than the B3.13 strain.
Migrating birds will carry it worldwide, raising the risk of mammalian outbreaks.
This is no longer just a U.S. issue it’s a global threat.
They got George Washington Carver in the lab working on PB2
September 28, 2026 at 3:31 AM
They got George Washington Carver in the lab working on PB2
PB1: "Dude, your pants are the wrong shade."
PB2: "yeah, my Mom ordered them."
PB2: "yeah, my Mom ordered them."
July 4, 2026 at 10:49 PM
PB1: "Dude, your pants are the wrong shade."
PB2: "yeah, my Mom ordered them."
PB2: "yeah, my Mom ordered them."
The H5N1 Bird Flu virus is showing concerning mutations, particularly the PB2 E627K mutation.
This mutation helps the virus adapt to mammals, including humans, and spread through the air.
It was present in the 1918 Spanish Flu, the Cambodian Bird Flu outbreak, and is now found in bobcats.
This mutation helps the virus adapt to mammals, including humans, and spread through the air.
It was present in the 1918 Spanish Flu, the Cambodian Bird Flu outbreak, and is now found in bobcats.
January 27, 2025 at 3:57 PM
The H5N1 Bird Flu virus is showing concerning mutations, particularly the PB2 E627K mutation.
This mutation helps the virus adapt to mammals, including humans, and spread through the air.
It was present in the 1918 Spanish Flu, the Cambodian Bird Flu outbreak, and is now found in bobcats.
This mutation helps the virus adapt to mammals, including humans, and spread through the air.
It was present in the 1918 Spanish Flu, the Cambodian Bird Flu outbreak, and is now found in bobcats.
RED ALARM on H5N1. Data dump late last night from the BC teen shows that the sequence has picked up the necessary mutation needed for adequate transmission among human hosts. It’s got PB2 E627K. The same mutation that 1918 Spanish influenza had. We’re going to have a pandemic.
Buckle up.
Buckle up.
November 16, 2024 at 1:50 PM
RED ALARM on H5N1. Data dump late last night from the BC teen shows that the sequence has picked up the necessary mutation needed for adequate transmission among human hosts. It’s got PB2 E627K. The same mutation that 1918 Spanish influenza had. We’re going to have a pandemic.
Buckle up.
Buckle up.
6/ Key concern: The virus in dairy cattle carries a PB2 D701N mutation, known to enhance adaptation in mammals. This change has been seen in human H5 infections but has NOT led to sustained human transmission.
February 10, 2025 at 2:21 PM
6/ Key concern: The virus in dairy cattle carries a PB2 D701N mutation, known to enhance adaptation in mammals. This change has been seen in human H5 infections but has NOT led to sustained human transmission.
Adding pb2 to my peanut butter to make another, more powerful, “double peanut butter”
April 18, 2025 at 5:25 PM
Adding pb2 to my peanut butter to make another, more powerful, “double peanut butter”
As an added GOF bonus, they also put E627K into PB2 so these viruses would replicate more efficiently in mice. PB2-E627K is known to increase fitness and pathogenicity in mammals. So these chimeric viruses are also the products of GOF virology research.
May 2, 2025 at 4:21 AM
As an added GOF bonus, they also put E627K into PB2 so these viruses would replicate more efficiently in mice. PB2-E627K is known to increase fitness and pathogenicity in mammals. So these chimeric viruses are also the products of GOF virology research.
"a change of PB2 D701N commonly associated with mammalian adaptation...
of HPAI...
from four separate dairy cattle"
Although H5N1 D1.1 seqs from Nevada Dairy Herds has not been uploaded to GISAID yet
APHIS update cites PB2 D710N
(Akin to E627K)
www.aphis.usda.gov/sites/defaul...
of HPAI...
from four separate dairy cattle"
Although H5N1 D1.1 seqs from Nevada Dairy Herds has not been uploaded to GISAID yet
APHIS update cites PB2 D710N
(Akin to E627K)
www.aphis.usda.gov/sites/defaul...
www.aphis.usda.gov
February 8, 2025 at 11:07 PM
"a change of PB2 D701N commonly associated with mammalian adaptation...
of HPAI...
from four separate dairy cattle"
Although H5N1 D1.1 seqs from Nevada Dairy Herds has not been uploaded to GISAID yet
APHIS update cites PB2 D710N
(Akin to E627K)
www.aphis.usda.gov/sites/defaul...
of HPAI...
from four separate dairy cattle"
Although H5N1 D1.1 seqs from Nevada Dairy Herds has not been uploaded to GISAID yet
APHIS update cites PB2 D710N
(Akin to E627K)
www.aphis.usda.gov/sites/defaul...
I just invented something yummy (if you’re into “healthy” shit): mix nonfat Greek yogurt with PB2 powder and honey and dip apple slices in it.
September 27, 2026 at 8:48 PM
I just invented something yummy (if you’re into “healthy” shit): mix nonfat Greek yogurt with PB2 powder and honey and dip apple slices in it.
Cattle B3.13 H5N1 viruses rapidly accumulated adaptations in polymerase genes that enabled better replication in bovine cells and tissues. PB2 M631L maps to the polymerase-ANP32 interface. PA K497R, PB2 E627K, PB2 D740N important.
👉 link.springer.com/article/10.1...
👉 link.springer.com/article/10.1...
January 18, 2026 at 10:26 PM
Cattle B3.13 H5N1 viruses rapidly accumulated adaptations in polymerase genes that enabled better replication in bovine cells and tissues. PB2 M631L maps to the polymerase-ANP32 interface. PA K497R, PB2 E627K, PB2 D740N important.
👉 link.springer.com/article/10.1...
👉 link.springer.com/article/10.1...
Mr. peanut butter AKA Peebs AKA PB2 AKA Peebles would like you to admire her hairdo
September 9, 2026 at 2:45 AM
Mr. peanut butter AKA Peebs AKA PB2 AKA Peebles would like you to admire her hairdo
I finally found a way to make yogurt palatable. Plain Greek yogurt, PB2 powder, swerve brown sugar, peanut protein granola, and sugar-free chocolate chips!!
May 16, 2025 at 4:57 PM
I finally found a way to make yogurt palatable. Plain Greek yogurt, PB2 powder, swerve brown sugar, peanut protein granola, and sugar-free chocolate chips!!