A 35-year-old man presented with a 2-year history of proximal muscle weakness with intermittent muscle cramping. Physical examination showed macroglossia and enlargement of the muscles in both calves.

Read the full case details: nej.md/3CjmTec

#MedSky #EndoSky

Before we knew that DMD even existed we thought that what we now know to be #pseudohypertrophy was just awesome healthy calf muscles. Sadly, we know better.
#duchennemusculardystrophy #dmd #duchenneawareness

youtu.be/vQMbzexFb5Q?...

Gemini said
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U01.01.053 Muscular Dystrophies MCQs: Duchenne, Becker & Myotonic Dystrophy Quiz

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Master the clinical and molecular biology of progressive muscle wasting disorders with our U01.01.053 Muscular Dystrophies question set. #MuscularDystrophy #Neurology #MedEd

Hypovolemia: pseudohypertrophy, low end-diastolic volume, may see interventricular gradients particularly in hypertrophy

"Congenital Muscular Pseudohypertrophy of the Upper Limb: Morphology, Anatomy and Surgical Guidelines of An Unique Entity" https://pubmed.ncbi.nlm.nih.gov/41825060/ #EvoDevo

On your neurological examination don't be fooled if the calve muscles look large, however on palpation they are 'doughy.' This is called pseudohypertrophy cause: infiltration of fat or connective tissue. Charcot's master Guillaume-Benjamin-Amand Duchenne (de Boulogne) described.