#publicationspotlight
#PublicationSpotlight 🔦

Why Are Some Cancer Cells Resistant to CAR-T Therapy?
Publication: YTHDF2 promotes ATP synthesis and immune evasion in B cell malignancies:

www.cell.com/cell/abstrac...

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YTHDF2 promotes ATP synthesis and immune evasion in B cell malignancies
YTHDF2 modulates oncogenic transformation and immune evasion across multiple B cell cancers by stabilizing m5C-modified mRNAs and destabilizing m6A-modified mRNAs, thereby serving as a dual reader for both m5C and m6A modifications. Small molecules that target YTHDF2 reduce ATP synthesis and are therapeutic candidates for B cell malignancies, especially when combined with CAR-T therapy or bispecific engagers.
ow.ly
January 10, 2025 at 11:05 AM
The study explores “seasonal shifts and individual variation in juvenile Atlantic cod (Gadus morhua) diel migration at nearshore nurseries”

Read more at: icefishresearch.com/light-acts-l...

#Atlanticcod #ICEFishResearch #sciencecommunication #Scicomm #publicationspotlight
Light acts like a natural timekeeper for young Atlantic cod
Many fish move around in regular patterns. One common type is called diel migration (dægurfar eða lóðréttar dægurgöngur), which means they move in a daily cycle
icefishresearch.com
May 15, 2026 at 12:18 PM