Research : doi.org/10.1039/D5CP...
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#congenitalhypothyroidism #diseaseswithcomputationalchemistry #humaniodotyrosinedeiodinase #moleculardynamicssimulation #qmmmcalculations
@rsc.org
#congenitalhypothyroidism #diseaseswithcomputationalchemistry #humaniodotyrosinedeiodinase #moleculardynamicssimulation #qmmmcalculations
Structural and catalytic consequences of active-site vs. distal mutations in human dehalogenase: insights from molecular dynamics simulations
Congenital hypothyroidism can result from mutations in human iodotyrosine deiodinase (hIYD), which catalyzes the deiodination of iodotyrosines (I-Tyr), a key step in thyroid hormone synthesis. Three…
doi.org
April 17, 2026 at 12:09 PM