Could naturally occurring antibodies hold the key to treating Parkinson's Disease?
Research shows autoantibodies targeting Alpha-Synuclein's NAC region can block toxic aggregation, studied using rPeptide's ASyn and defined fragments. 🧠
t.ly/rM9w3
#Neuroscience #ParkinsonsResearch #AlphaSynuclein
Research shows autoantibodies targeting Alpha-Synuclein's NAC region can block toxic aggregation, studied using rPeptide's ASyn and defined fragments. 🧠
t.ly/rM9w3
#Neuroscience #ParkinsonsResearch #AlphaSynuclein
Autoantibodies against α-synuclein inhibit its aggregation and cytotoxicity
Aggregates of α-synuclein (α-Syn) are the major component of the Lewy bodies associated with Parkinson's disease. Recently, naturally occurring autoan…
t.ly
September 30, 2026 at 3:32 PM
Could naturally occurring antibodies hold the key to treating Parkinson's Disease?
Research shows autoantibodies targeting Alpha-Synuclein's NAC region can block toxic aggregation, studied using rPeptide's ASyn and defined fragments. 🧠
t.ly/rM9w3
#Neuroscience #ParkinsonsResearch #AlphaSynuclein
Research shows autoantibodies targeting Alpha-Synuclein's NAC region can block toxic aggregation, studied using rPeptide's ASyn and defined fragments. 🧠
t.ly/rM9w3
#Neuroscience #ParkinsonsResearch #AlphaSynuclein
Using #rPeptide's high-purity recombinant #BetaAmyloid 1-40 (cat# A-1153) and 1-42 (cat# A-1163) as the aggregation substrates in these experiments allowed the researchers to reliably monitor how MDK affects fibril formation.
t.ly/_ebGd
#AlzheimersResearch
t.ly/_ebGd
#AlzheimersResearch
Peptides Archives
t.ly
December 15, 2025 at 6:17 PM
Using #rPeptide's high-purity recombinant #BetaAmyloid 1-40 (cat# A-1153) and 1-42 (cat# A-1163) as the aggregation substrates in these experiments allowed the researchers to reliably monitor how MDK affects fibril formation.
t.ly/_ebGd
#AlzheimersResearch
t.ly/_ebGd
#AlzheimersResearch
What if you could clear Alpha-Synuclein aggregates and restore dopamine neurons wirelessly?
This Science Advances research does exactly that using a photothermal nanosystem, studied using rPeptide's Alpha-Synuclein (S-1001). 🧠
t.ly/stiVv
#Neuroscience #ParkinsonsResearch #AlphaSynuclein
This Science Advances research does exactly that using a photothermal nanosystem, studied using rPeptide's Alpha-Synuclein (S-1001). 🧠
t.ly/stiVv
#Neuroscience #ParkinsonsResearch #AlphaSynuclein
A nanoparticle-based wireless deep brain stimulation system that reverses Parkinson’s disease
Nanoparticle-mediated wireless system reverses Parkinson’s disease.
t.ly
September 2, 2026 at 4:06 PM
What if you could clear Alpha-Synuclein aggregates and restore dopamine neurons wirelessly?
This Science Advances research does exactly that using a photothermal nanosystem, studied using rPeptide's Alpha-Synuclein (S-1001). 🧠
t.ly/stiVv
#Neuroscience #ParkinsonsResearch #AlphaSynuclein
This Science Advances research does exactly that using a photothermal nanosystem, studied using rPeptide's Alpha-Synuclein (S-1001). 🧠
t.ly/stiVv
#Neuroscience #ParkinsonsResearch #AlphaSynuclein
While a generic Tau K19 fragment was used, rPeptide’s Tau K19, C322S Mutant offers a high-quality alternative for similar studies. This research underscores how rPeptide tools can help advance the investigation of key disease mechanisms!
July 9, 2025 at 3:29 PM
While a generic Tau K19 fragment was used, rPeptide’s Tau K19, C322S Mutant offers a high-quality alternative for similar studies. This research underscores how rPeptide tools can help advance the investigation of key disease mechanisms!
This @alzdemjournals.bsky.social study identifies the Tau isoform 1N4R as a key driver of neuronal vulnerability to #AmyloidBeta and phosphorylated #Tau in MAPT knockout human iPSC-derived neurons. rPeptide’s Aβ40 and Aβ42 was used to model AD-related toxicity.
Paper: t.ly/XFF_6
BA: t.ly/QLggQ
Paper: t.ly/XFF_6
BA: t.ly/QLggQ
The tau isoform 1N4R confers vulnerability of MAPT knockout human iPSC‐derived neurons to amyloid beta and phosphorylated tau‐induced neuronal dysfunction
INTRODUCTION Human tau protein, composed of six brain-specific isoforms, is a major driver of Alzheimer's disease (AD). The role of its isoforms however remains unclear and human AD models are scarc...
t.ly
May 12, 2025 at 3:48 PM
This @alzdemjournals.bsky.social study identifies the Tau isoform 1N4R as a key driver of neuronal vulnerability to #AmyloidBeta and phosphorylated #Tau in MAPT knockout human iPSC-derived neurons. rPeptide’s Aβ40 and Aβ42 was used to model AD-related toxicity.
Paper: t.ly/XFF_6
BA: t.ly/QLggQ
Paper: t.ly/XFF_6
BA: t.ly/QLggQ
How do neurons, astrocytes, and microglia respond to amyloid together?
A triple co-culture model recapitulates key Alzheimer's Disease hallmarks in vitro, studied using rPeptide's FITC-labeled Beta-Amyloid (1-42). 🧠
t.ly/GypTw
#Neuroscience #AlzheimersResearch #Neuroinflammation
A triple co-culture model recapitulates key Alzheimer's Disease hallmarks in vitro, studied using rPeptide's FITC-labeled Beta-Amyloid (1-42). 🧠
t.ly/GypTw
#Neuroscience #AlzheimersResearch #Neuroinflammation
Preparing to download ...
t.ly
June 22, 2026 at 2:37 PM
How do neurons, astrocytes, and microglia respond to amyloid together?
A triple co-culture model recapitulates key Alzheimer's Disease hallmarks in vitro, studied using rPeptide's FITC-labeled Beta-Amyloid (1-42). 🧠
t.ly/GypTw
#Neuroscience #AlzheimersResearch #Neuroinflammation
A triple co-culture model recapitulates key Alzheimer's Disease hallmarks in vitro, studied using rPeptide's FITC-labeled Beta-Amyloid (1-42). 🧠
t.ly/GypTw
#Neuroscience #AlzheimersResearch #Neuroinflammation
rPeptide's new ABT Fibril Complex consists of Tau-441, Beta-Amyloid 1-42, and Alpha-Synuclein together in one validated system. Built for the complexity of real Alzheimer's pathology. 🔬
ABT Fibril Complex: t.ly/g4Jpk
#rPeptide #PFFs #Alzheimers #Neurodegeneration #Tau #AlphaSynuclein #BetaAmyloid
ABT Fibril Complex: t.ly/g4Jpk
#rPeptide #PFFs #Alzheimers #Neurodegeneration #Tau #AlphaSynuclein #BetaAmyloid
March 13, 2026 at 1:58 PM
rPeptide's new ABT Fibril Complex consists of Tau-441, Beta-Amyloid 1-42, and Alpha-Synuclein together in one validated system. Built for the complexity of real Alzheimer's pathology. 🔬
ABT Fibril Complex: t.ly/g4Jpk
#rPeptide #PFFs #Alzheimers #Neurodegeneration #Tau #AlphaSynuclein #BetaAmyloid
ABT Fibril Complex: t.ly/g4Jpk
#rPeptide #PFFs #Alzheimers #Neurodegeneration #Tau #AlphaSynuclein #BetaAmyloid
A new stem cell-based model is helping researchers understand how the brain's protective barrier breaks down in Alzheimer's Disease.
rPeptide's Beta-Amyloid (1-42) was used to test how Aβ exposure affects barrier function.
t.ly/MMEBo
#AlzheimersResearch #BloodBrainBarrier #Neuroscience
rPeptide's Beta-Amyloid (1-42) was used to test how Aβ exposure affects barrier function.
t.ly/MMEBo
#AlzheimersResearch #BloodBrainBarrier #Neuroscience
American Heart Association Journals
t.ly
April 29, 2026 at 6:45 PM
A new stem cell-based model is helping researchers understand how the brain's protective barrier breaks down in Alzheimer's Disease.
rPeptide's Beta-Amyloid (1-42) was used to test how Aβ exposure affects barrier function.
t.ly/MMEBo
#AlzheimersResearch #BloodBrainBarrier #Neuroscience
rPeptide's Beta-Amyloid (1-42) was used to test how Aβ exposure affects barrier function.
t.ly/MMEBo
#AlzheimersResearch #BloodBrainBarrier #Neuroscience
#Researchers explored the differential immune responses of aged versus young microglial cells. To investigate the role of Amyloid-Beta in these processes, they utilized rPeptide’s #BetaAmyloid 1-42 #AggregationKit to prepare and treat cells ahead of phagocytosis assays.
t.ly/2GGAM
BA: t.ly/qtpHs
t.ly/2GGAM
BA: t.ly/qtpHs
Age-associated microglial transcriptome leads to diminished immunogenicity and dysregulation of MCT4 and P2RY12/P2RY13 related functions - Cell Death Discovery
Cell Death Discovery - Age-associated microglial transcriptome leads to diminished immunogenicity and dysregulation of MCT4 and P2RY12/P2RY13 related functions
t.ly
June 23, 2025 at 1:44 PM
#Researchers explored the differential immune responses of aged versus young microglial cells. To investigate the role of Amyloid-Beta in these processes, they utilized rPeptide’s #BetaAmyloid 1-42 #AggregationKit to prepare and treat cells ahead of phagocytosis assays.
t.ly/2GGAM
BA: t.ly/qtpHs
t.ly/2GGAM
BA: t.ly/qtpHs
Nature Neuroscience research transplants human stem cell-derived microglia into mouse brains to study uniquely human microglial responses to Beta-Amyloid in Alzheimer's Disease. Study conducted using rPeptide's BA 1-42 (A-1163) and BA Scrambled A-1104.
t.ly/fuQCs
#Neuroscience #AlzheimersResearch
t.ly/fuQCs
#Neuroscience #AlzheimersResearch
Stem-cell-derived human microglia transplanted in mouse brain to study human disease - Nature Neuroscience
Human stem cell-derived microglia integrate into mouse brain, displaying transcriptome signatures of microglia directly isolated from human brain and providing a chimeric model to study human-specific...
t.ly
July 1, 2026 at 7:44 PM
Nature Neuroscience research transplants human stem cell-derived microglia into mouse brains to study uniquely human microglial responses to Beta-Amyloid in Alzheimer's Disease. Study conducted using rPeptide's BA 1-42 (A-1163) and BA Scrambled A-1104.
t.ly/fuQCs
#Neuroscience #AlzheimersResearch
t.ly/fuQCs
#Neuroscience #AlzheimersResearch
An α-Syn seed amplification assay shows promise for detecting Lewy body dementia via CSF, helping differentiate synucleinopathies from AD for earlier, more accurate diagnosis. Powered in part by rPeptide's recombinant Alpha-Synuclein. 🧬🧠
t.ly/UaBAZ
#AlphaSynuclein #LewyBody #Parkinsons #rPeptide
t.ly/UaBAZ
#AlphaSynuclein #LewyBody #Parkinsons #rPeptide
Diagnostic Performance of the α-Synuclein Seed Amplification Assay for Dementia With Lewy Bodies | Neurology
Background and ObjectivesThe α-synuclein (α-syn) seed amplification assay (SAA) has shown promising results
for diagnosing dementia with Lewy bodies (DLB) using CSF samples. A barrier to implementing
...
t.ly
March 16, 2026 at 5:57 PM
An α-Syn seed amplification assay shows promise for detecting Lewy body dementia via CSF, helping differentiate synucleinopathies from AD for earlier, more accurate diagnosis. Powered in part by rPeptide's recombinant Alpha-Synuclein. 🧬🧠
t.ly/UaBAZ
#AlphaSynuclein #LewyBody #Parkinsons #rPeptide
t.ly/UaBAZ
#AlphaSynuclein #LewyBody #Parkinsons #rPeptide
Why do Alzheimer's mutations shift Aβ toward longer, more toxic forms? Cell research shows they destabilize gamma-secretase enzyme-substrate complexes, studied using rPeptide's Beta-Amyloid (1-38), (1-40), (1-42), (1-43), and (1-46). 🧠
t.ly/xq-n_
#Neuroscience #AlzheimersResearch #BetaAmyloid
t.ly/xq-n_
#Neuroscience #AlzheimersResearch #BetaAmyloid
t.ly
July 20, 2026 at 4:15 PM
Why do Alzheimer's mutations shift Aβ toward longer, more toxic forms? Cell research shows they destabilize gamma-secretase enzyme-substrate complexes, studied using rPeptide's Beta-Amyloid (1-38), (1-40), (1-42), (1-43), and (1-46). 🧠
t.ly/xq-n_
#Neuroscience #AlzheimersResearch #BetaAmyloid
t.ly/xq-n_
#Neuroscience #AlzheimersResearch #BetaAmyloid
Well-characterized mutant protein models are essential for studying Alpha-Synuclein aggregation and transmission.
rPeptide's Alpha-Synuclein A53T Mutant (S-1002) is available to support your research!
t.ly/3h6cg
#Recombinant #Proteins #Peptides #rPeptide
rPeptide's Alpha-Synuclein A53T Mutant (S-1002) is available to support your research!
t.ly/3h6cg
#Recombinant #Proteins #Peptides #rPeptide
Alpha-Synuclein, A53T Mutant
High quality recombinant Alpha-Synuclein, A53T Mutant, >95% purity. Highly monomeric, batch to batch consistency. Order online today.
t.ly
June 15, 2026 at 7:16 PM
Well-characterized mutant protein models are essential for studying Alpha-Synuclein aggregation and transmission.
rPeptide's Alpha-Synuclein A53T Mutant (S-1002) is available to support your research!
t.ly/3h6cg
#Recombinant #Proteins #Peptides #rPeptide
rPeptide's Alpha-Synuclein A53T Mutant (S-1002) is available to support your research!
t.ly/3h6cg
#Recombinant #Proteins #Peptides #rPeptide
To track these protein structures in detail, the team used rPeptide’s Uniformly Labeled 15N Alpha-Synuclein (t.ly/UCZ4n), which allowed for high-resolution NMR analysis of α-Synuclein behavior.
N15 Alpha-Synuclein, Uniformly Labeled
High quality recombinant N15 Alpha-Synuclein, >95% purity. Highly monomeric, batch to batch consistency. Order online today - R&D starts at rPeptide.
t.ly
July 30, 2025 at 3:26 PM
To track these protein structures in detail, the team used rPeptide’s Uniformly Labeled 15N Alpha-Synuclein (t.ly/UCZ4n), which allowed for high-resolution NMR analysis of α-Synuclein behavior.
Could circadian clock disruption drive sex-specific Tau pathology?
Research shows microglial REV-ERBα deletion impairs Tau clearance and worsens tauopathy only in males, using rPeptide's FITC-labeled Tau-441. 🧠
t.ly/NWOV5
#Neuroscience #Tauopathy #AlzheimersResearch
Research shows microglial REV-ERBα deletion impairs Tau clearance and worsens tauopathy only in males, using rPeptide's FITC-labeled Tau-441. 🧠
t.ly/NWOV5
#Neuroscience #Tauopathy #AlzheimersResearch
Microglial REV-ERBα regulates inflammation and lipid droplet formation to drive tauopathy in male mice - Nature Communications
The circadian clock protein REV-ERBα has been implicated in neuroinflammation but mechanisms are poorly understood. Here, the authors show that microglial REV-ERBα regulates inflammatory signaling and...
t.ly
September 18, 2026 at 4:42 PM
Could circadian clock disruption drive sex-specific Tau pathology?
Research shows microglial REV-ERBα deletion impairs Tau clearance and worsens tauopathy only in males, using rPeptide's FITC-labeled Tau-441. 🧠
t.ly/NWOV5
#Neuroscience #Tauopathy #AlzheimersResearch
Research shows microglial REV-ERBα deletion impairs Tau clearance and worsens tauopathy only in males, using rPeptide's FITC-labeled Tau-441. 🧠
t.ly/NWOV5
#Neuroscience #Tauopathy #AlzheimersResearch
To examine the implications of CMA dysfunction, rPeptide’s Tau-441 was used to assess #Tau behavior under these impaired conditions.
t.ly/2bKKW
This provides insight into the molecular links between #lysosomaldysfunction and #proteinaccumulation in #Parkinsons and #Alzheimers diseases.
t.ly/2bKKW
This provides insight into the molecular links between #lysosomaldysfunction and #proteinaccumulation in #Parkinsons and #Alzheimers diseases.
Tau-441
Recombinant Tau-441 from rPeptide. High quality, >90% purity, batch to batch consistency. In stock and ready to ship - order online today.
www.rpeptide.com
August 11, 2025 at 1:59 PM
To examine the implications of CMA dysfunction, rPeptide’s Tau-441 was used to assess #Tau behavior under these impaired conditions.
t.ly/2bKKW
This provides insight into the molecular links between #lysosomaldysfunction and #proteinaccumulation in #Parkinsons and #Alzheimers diseases.
t.ly/2bKKW
This provides insight into the molecular links between #lysosomaldysfunction and #proteinaccumulation in #Parkinsons and #Alzheimers diseases.
This work highlights critical molecular targets for therapeutic intervention in #Alzheimers and related neurodegenerative diseases. rPeptide’s Aβ42 reagent was vital for reproducing the oligomeric species central to these disease mechanisms.
t.ly/U7xpv
#Research #Development #Peptide #rPeptide
t.ly/U7xpv
#Research #Development #Peptide #rPeptide
Beta-Amyloid (1-42), HFIP
High quality recombinant Beta-Amyloid (1-42), HFIP, >97% purity. Highly monomeric, batch to batch consistency. Order online today - R&D starts at rPeptide.
t.ly
August 6, 2025 at 12:58 PM
This work highlights critical molecular targets for therapeutic intervention in #Alzheimers and related neurodegenerative diseases. rPeptide’s Aβ42 reagent was vital for reproducing the oligomeric species central to these disease mechanisms.
t.ly/U7xpv
#Research #Development #Peptide #rPeptide
t.ly/U7xpv
#Research #Development #Peptide #rPeptide
To model neurodegeneration, our Beta-Amyloid 1–42 was used - it was found that select compounds could reduce BA induced cell damage. This work highlights how rPeptide’s tools enable researchers to screen new therapeutic compounds under disease-relevant conditions.
t.ly/tkZYw
#BetaAmyloid #BA42
t.ly/tkZYw
#BetaAmyloid #BA42
Beta-Amyloid (1-42), TFA
High quality recombinant Beta-Amyloid (1-42), TFA, >97% purity. Highly monomeric, batch to batch consistency. Order online today - R&D starts at rPeptide.
t.ly
September 10, 2025 at 12:39 PM
To model neurodegeneration, our Beta-Amyloid 1–42 was used - it was found that select compounds could reduce BA induced cell damage. This work highlights how rPeptide’s tools enable researchers to screen new therapeutic compounds under disease-relevant conditions.
t.ly/tkZYw
#BetaAmyloid #BA42
t.ly/tkZYw
#BetaAmyloid #BA42
New sensors can now light up and map Alzheimer's plaques in the brain 🧠🔬
Curcumin-based near infrared tech is opening new doors for disease research validated with rPeptide's Beta-Amyloid 1-40.
t.ly/yg4Gb
#AlzheimersResearch #BrainHealth #BetaAmyloid #Neuroscience
Curcumin-based near infrared tech is opening new doors for disease research validated with rPeptide's Beta-Amyloid 1-40.
t.ly/yg4Gb
#AlzheimersResearch #BrainHealth #BetaAmyloid #Neuroscience
Visualizing and mapping Aβ plaques by curcumin-derived NIR sensors: Multitarget theranostic agents for Alzheimer's disease
Two curcumin derivatives, structurally related to the CRANAD family of compounds, were investigated for their theranostic properties in Alzheimer's di…
t.ly
April 8, 2026 at 4:49 PM
New sensors can now light up and map Alzheimer's plaques in the brain 🧠🔬
Curcumin-based near infrared tech is opening new doors for disease research validated with rPeptide's Beta-Amyloid 1-40.
t.ly/yg4Gb
#AlzheimersResearch #BrainHealth #BetaAmyloid #Neuroscience
Curcumin-based near infrared tech is opening new doors for disease research validated with rPeptide's Beta-Amyloid 1-40.
t.ly/yg4Gb
#AlzheimersResearch #BrainHealth #BetaAmyloid #Neuroscience
Could targeting CD22 both reduce neuroinflammation and clear Aβ in Alzheimer's Disease?
Research demonstrates a dual mechanism for suciraslimab in microglia, using rPeptide's Beta-Amyloid (1-42) HFIP (A-1163-1) and Fluorescein Aβ (1-42) (A-1119-1). 🧠
t.ly/LWYf9
#Neuroscience #AlzheimersResearch
Research demonstrates a dual mechanism for suciraslimab in microglia, using rPeptide's Beta-Amyloid (1-42) HFIP (A-1163-1) and Fluorescein Aβ (1-42) (A-1119-1). 🧠
t.ly/LWYf9
#Neuroscience #AlzheimersResearch
CD22 modulation alleviates amyloid β-induced neuroinflammation
Neuroinflammation is a crucial driver of multiple neurodegenerative diseases, including Alzheimer’s disease (AD), amyotrophic lateral sclerosis (ALS) and Parkinson’s disease (PD). Yet, therapeutic tar...
t.ly
September 9, 2026 at 3:45 PM
Could targeting CD22 both reduce neuroinflammation and clear Aβ in Alzheimer's Disease?
Research demonstrates a dual mechanism for suciraslimab in microglia, using rPeptide's Beta-Amyloid (1-42) HFIP (A-1163-1) and Fluorescein Aβ (1-42) (A-1119-1). 🧠
t.ly/LWYf9
#Neuroscience #AlzheimersResearch
Research demonstrates a dual mechanism for suciraslimab in microglia, using rPeptide's Beta-Amyloid (1-42) HFIP (A-1163-1) and Fluorescein Aβ (1-42) (A-1119-1). 🧠
t.ly/LWYf9
#Neuroscience #AlzheimersResearch
This Nature Neuroscience research finds phosphorylated Tau impairs neurovascular coupling before neuronal loss or cognitive decline, pinpointing a nitric oxide deficit as the mechanism. Study conducted using rPeptide's Tau-441 P301L Mutant. 🔬
t.ly/f6pI5
#Neuroscience #Tauopathy #AlzheimersResearch
t.ly/f6pI5
#Neuroscience #Tauopathy #AlzheimersResearch
Tau induces PSD95–neuronal NOS uncoupling and neurovascular dysfunction independent of neurodegeneration - Nature Neuroscience
Park et al. demonstrate in tauopathy models that tau disrupts the interaction between neuronal nitric oxide synthase and PSD95, uncoupling glutamatergic synaptic activity from nitric oxide production ...
t.ly
July 8, 2026 at 12:54 PM
This Nature Neuroscience research finds phosphorylated Tau impairs neurovascular coupling before neuronal loss or cognitive decline, pinpointing a nitric oxide deficit as the mechanism. Study conducted using rPeptide's Tau-441 P301L Mutant. 🔬
t.ly/f6pI5
#Neuroscience #Tauopathy #AlzheimersResearch
t.ly/f6pI5
#Neuroscience #Tauopathy #AlzheimersResearch
Early-stage Tau folding may be the trigger for Alzheimer's aggregation. A new study tracks structural changes before fibrils even form. rPeptide's Tau-441 (Cat# T-1001) supported the research 🧬🧠
t.ly/60OGC
#Alzheimers #Neuroscience #TauProtein #Tauopathy #rPeptide
t.ly/60OGC
#Alzheimers #Neuroscience #TauProtein #Tauopathy #rPeptide
Conformation-specific monoclonal antibodies reveal early Tau structural intermediates in Alzheimer’s disease
Tauopathy, including Alzheimer’s disease, is the most prevalent neurodegenerative
disorder, yet current therapies fail to halt disease progression, partly because of
limited understanding of early tau...
t.ly
March 11, 2026 at 6:51 PM
Early-stage Tau folding may be the trigger for Alzheimer's aggregation. A new study tracks structural changes before fibrils even form. rPeptide's Tau-441 (Cat# T-1001) supported the research 🧬🧠
t.ly/60OGC
#Alzheimers #Neuroscience #TauProtein #Tauopathy #rPeptide
t.ly/60OGC
#Alzheimers #Neuroscience #TauProtein #Tauopathy #rPeptide
Early loss of smell may be more than a symptom, it may reflect early #Parkinsons pathology.
A new study shows #AlphaSynuclein aggregation drives both neuron loss and olfactory deficits in PD models. rPeptide’s Alpha-Synuclein and ready-to-use PFFs supported this work.
t.ly/ouvq9
#rPeptide
A new study shows #AlphaSynuclein aggregation drives both neuron loss and olfactory deficits in PD models. rPeptide’s Alpha-Synuclein and ready-to-use PFFs supported this work.
t.ly/ouvq9
#rPeptide
Dopaminergic neurodegeneration in the substantia nigra is associated with olfactory dysfunction in mice models of Parkinson’s disease - Cell Death Discovery
Cell Death Discovery - Dopaminergic neurodegeneration in the substantia nigra is associated with olfactory dysfunction in mice models of Parkinson’s disease
t.ly
January 19, 2026 at 6:42 PM
Early loss of smell may be more than a symptom, it may reflect early #Parkinsons pathology.
A new study shows #AlphaSynuclein aggregation drives both neuron loss and olfactory deficits in PD models. rPeptide’s Alpha-Synuclein and ready-to-use PFFs supported this work.
t.ly/ouvq9
#rPeptide
A new study shows #AlphaSynuclein aggregation drives both neuron loss and olfactory deficits in PD models. rPeptide’s Alpha-Synuclein and ready-to-use PFFs supported this work.
t.ly/ouvq9
#rPeptide
A new study shows soluble Tau aggregates may disrupt brain rhythms by making thalamic neurons more excitable
With rPeptide’s Tau-441 PFFs t.ly/p0Ykf, researchers modeled early Tau pathology in mice to reveal how these aggregates alter brain signaling
t.ly/Ss8w5
#Neuroscience #Tauopathy #Research
With rPeptide’s Tau-441 PFFs t.ly/p0Ykf, researchers modeled early Tau pathology in mice to reveal how these aggregates alter brain signaling
t.ly/Ss8w5
#Neuroscience #Tauopathy #Research
Soluble tau aggregates decrease the threshold for thalamic oscillations and increase the excitability of thalamic neurons
Sleep disturbances frequently occur early in dementias such as Alzheimer's disease (AD) and potentially arise from many factors including cortico-thal…
t.ly
September 3, 2025 at 1:14 PM
A new study shows soluble Tau aggregates may disrupt brain rhythms by making thalamic neurons more excitable
With rPeptide’s Tau-441 PFFs t.ly/p0Ykf, researchers modeled early Tau pathology in mice to reveal how these aggregates alter brain signaling
t.ly/Ss8w5
#Neuroscience #Tauopathy #Research
With rPeptide’s Tau-441 PFFs t.ly/p0Ykf, researchers modeled early Tau pathology in mice to reveal how these aggregates alter brain signaling
t.ly/Ss8w5
#Neuroscience #Tauopathy #Research
Which Alpha-Synuclein sequences drive toxic aggregation in Parkinson's Disease? This research identifies and validates key N-terminal targets using foldamers, with rPeptide's N15-labeled Alpha-Synuclein (S-1004-2) enabling atomic-level NMR mapping. 🧠
t.ly/02WMa
#Neuroscience #ParkinsonsResearch
t.ly/02WMa
#Neuroscience #ParkinsonsResearch
Foldamers reveal and validate therapeutic targets associated with toxic α-synuclein self-assembly - Nature Communications
Inhibiting alpha-synuclein self-assembly into amyloid structures, associated with Parkinson’s disease, is a potential therapeutic intervention. Here, the authors identify the domains/sequences that ar...
t.ly
August 5, 2026 at 5:23 PM
Which Alpha-Synuclein sequences drive toxic aggregation in Parkinson's Disease? This research identifies and validates key N-terminal targets using foldamers, with rPeptide's N15-labeled Alpha-Synuclein (S-1004-2) enabling atomic-level NMR mapping. 🧠
t.ly/02WMa
#Neuroscience #ParkinsonsResearch
t.ly/02WMa
#Neuroscience #ParkinsonsResearch