Ski8's dual affiliation in PAF1C and the SKI complex is an interesting example (though not well understood AFAIK)

Another favorite (again germline biology, but I'm biased) is the dynein light chain protein moonlighting as a Piwi helper (PMIDs: 33574069 + 33538693)

A 4 channel Amiga .mod playing on a stock C64, in under 32kbytes. So. How low can you go?

Download: csdb.dk/release/?id=...
Youtube: www.youtube.com/watch?v=ski8...

#c64 #commodore #digi #samples #demoscene #revision #hardstyle #lofi

【鉄拳8】

次はPHASE1日本勢最後の一人、ダブル氏がいるグループGG。ダブル氏は、AO氏とチクリン氏が待つPHASE2進出を目指す。

世界最重要対戦格闘ゲームイベント「高額賞金大会 Esports World Cup 2024 - 鉄拳8部門 Day2」配信中

▼日本向けライブ配信
・Twitch 実況解説はゲンヤ氏とハメコ。氏
( twitch.tv/EWC_FIGHTERS... )
・YouTube
( www.youtube.com/watch?v=9zzi... )
・ユウ氏による応援ミラー配信
( www.youtube.com/watch?v=SKi8... )

【鉄拳8】

日本勢3人目となるダブル氏がPHASE1通過。

世界最重要対戦格闘ゲームイベント「Esports World Cup 2024 - 鉄拳8部門 Day2」配信中

▼日本向け配信
・Twitch 実況解説はゲンヤ氏とハメコ。氏
( twitch.tv/EWC_FIGHTERS... )
・YouTube
( www.youtube.com/watch?v=9zzi... )
・ユウ氏による応援ミラー
( www.youtube.com/watch?v=SKi8... )
・日本語実況+応援の2画面
( www.twitchtheater.tv/v=9zziZdZ1Ak... )

merc.li/xFuFJMTyb?sv=0
#van's #vans #skateboarding #ski8 #skateboardingShoes

Discover how SKI2, SKI3, and SKI8 in #Arabidopsis limit secondary siRNA by degrading RISC 5'-cleavage fragments, revealing new insights into miRNA target regulation. 🌱💡 #Research #GeneSilencing PMID:26464441, Nucleic Acids Res 2016, @NAR_Open doi.org/10.1093/nar/...

Finally, we found that Rec102 also interacts with Ski8 across the dimerization plane. Mutation of an interface residue reduces Rec102-Ski8 interaction, dimerization of the core complex on DNA, and meiotic DSB formation.

Spo11 cleaves DNA via a topoisomerase-like mechanism involving hybrid active sites located at the dimer interface. Spo11 forms a complex with Ski8, Rec102 and Rec104, but unlike its topoisomerase relative, the complex has a monomeric (1:1:1:1) stoichiometry. How does it dimerize?