#snPATHO
Fairly promising stuff in the spatial RNA-Seq world. Good to see some local Adelaide people kicking goals too. @beardymcjohnface.bsky.social

www.nature.com/articles/s42...
snPATHO-seq, a versatile FFPE single-nucleus RNA sequencing method to unlock pathology archives - Communications Biology
A combination of an FFPE nuclei preparation protocol and a probe-based transcriptomic profiling technique enables snRNA-seq characterization of archival human FFPE tissues, holding promise for retrosp...
www.nature.com
October 17, 2024 at 3:21 AM
Thx @hoheyn.bsky.social & Sabine Tejpar for getting/keeping the game afoot;
KU Leuven & @brukerspatial.bsky.social teams for your support.

These data were no breeze yet real gratifying; in brief:

- we survey 3.5M cells (1.6k FOVs = 4.3cm2) via WTx CosMx SMI & snPATHO-seq + digital histopatholgy
June 27, 2025 at 6:33 PM
snPATHO-seq: unlocking the pathology archives https://www.biorxiv.org/content/10.1101/2023.12.07.570700v1
snPATHO-seq: unlocking the pathology archives https://www.biorxiv.org/content/10.1101/2023.12.07.570700v1
Formalin-fixed paraffin-embedded (FFPE) samples are valuable but underutilized in single-cell omics
www.biorxiv.org
December 9, 2023 at 1:23 AM
snPATHO-seq: unlocking the pathology archives https://www.biorxiv.org/content/10.1101/2023.12.07.570700v1
snPATHO-seq: unlocking the pathology archives https://www.biorxiv.org/content/10.1101/2023.12.07.570700v1
Formalin-fixed paraffin-embedded (FFPE) samples are valuable but underutilized in single-cell omics
www.biorxiv.org
December 9, 2023 at 1:23 AM