#sultamicillin
Interesting insights also into Sultamicillin, a codrug that brings together a β-lactam (ampicillin) and a β-lactamase inhibitor (sulbactam) in one molecule that is orally bioavailable and gets activated into the two active ingredients by esterases. (4/4) journals.asm.org/doi/10.1128/...
Pharmacokinetics of sultamicillin in mice, rats, and dogs | Antimicrobial Agents and Chemotherapy
The irreversible beta-lactamase inhibitor sulbactam has been combined chemically via ester linkages with ampicillin to form sultamicillin . Upon oral absorption, sultamicillin is completely hydrolyzed...
journals.asm.org
January 21, 2025 at 10:19 AM
April 20, 2026 at 8:07 AM