July 30, 2025 at 9:09 PM
September 13, 2026 at 8:07 AM
A project five years in the making, we've now published complete "T2T" genomes for six additional ape species! It turns out that finishing (and analyzing) six genomes is slightly more work than one... doi.org/10.1038/s415...
April 9, 2025 at 9:31 PM
A project five years in the making, we've now published complete "T2T" genomes for six additional ape species! It turns out that finishing (and analyzing) six genomes is slightly more work than one... doi.org/10.1038/s415...
Preprint on hifiasm Nanopore-only assembly. Led by Haoyu Cheng: www.biorxiv.org/content/10.1...
Efficient near telomere-to-telomere assembly of Nanopore Simplex reads
Telomere-to-telomere (T2T) assembly is the ultimate goal for de novo genome assembly. Existing algorithms capable of near T2T assembly all require Oxford Nanopore Technologies (ONT) ultra-long reads w...
www.biorxiv.org
April 18, 2025 at 9:54 PM
Preprint on hifiasm Nanopore-only assembly. Led by Haoyu Cheng: www.biorxiv.org/content/10.1...
Teto-to-Teto (T2T) communication
June 27, 2025 at 4:25 PM
Teto-to-Teto (T2T) communication
Folks, it is finally out! Our paper on T2T assemblies of the zebrafish genome is on BioRxiv:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
www.biorxiv.org
November 17, 2025 at 11:22 PM
Folks, it is finally out! Our paper on T2T assemblies of the zebrafish genome is on BioRxiv:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
The T2T zebra finch genome has hatched! 🐣 🧬 @vertebrategenomes.bsky.social
The complete genome of a songbird https://www.biorxiv.org/content/10.1101/2025.10.14.682431v1
October 15, 2025 at 1:08 PM
The T2T zebra finch genome has hatched! 🐣 🧬 @vertebrategenomes.bsky.social
There is SO MUCH data. You can find it all organized here: github.com/marbl/Primates And certainly don't overlook the T2T Browser Hub that we've been gradually adding to that contains expression, methylation, genes, repeats, etc. for all of these species github.com/marbl/T2T-Br...
GitHub - marbl/T2T-Browser: Genome browser hub for the T2T genomes and resources
Genome browser hub for the T2T genomes and resources - marbl/T2T-Browser
github.com
April 9, 2025 at 9:35 PM
There is SO MUCH data. You can find it all organized here: github.com/marbl/Primates And certainly don't overlook the T2T Browser Hub that we've been gradually adding to that contains expression, methylation, genes, repeats, etc. for all of these species github.com/marbl/T2T-Br...
It's Valve, so they're probably still stuck on T2T
November 13, 2025 at 10:41 PM
It's Valve, so they're probably still stuck on T2T
they're about to downgrade me to T2T 😭
if you fall for a cis woman you get downgraded to t3t
May 23, 2024 at 10:52 AM
they're about to downgrade me to T2T 😭
With these improvements, Verkko2 can now assemble ~40/46 diploid human chromosomes as T2T scaffolds (and ~20 as T2T contigs). This release represents a ton of work from @dantipov.bsky.social, Mikko Rautiainen, and @sergek.bsky.social Looking forward to many more T2T genomes generated in 2025! 🎆
January 2, 2025 at 3:28 PM
With these improvements, Verkko2 can now assemble ~40/46 diploid human chromosomes as T2T scaffolds (and ~20 as T2T contigs). This release represents a ton of work from @dantipov.bsky.social, Mikko Rautiainen, and @sergek.bsky.social Looking forward to many more T2T genomes generated in 2025! 🎆
T2T roadshow this week! ✈️ Monday, ESHG talk on personalized genomes and Robertsonians ✈️ Wednesday, Sanger ToL talk on great ape acrocentric chromosomes 🚂 Thursday, QMUL talk on a little bit of both 🚇 Friday, London reunion with T2T legend @sergeynurk.bsky.social 🎉
June 13, 2026 at 12:22 PM
T2T roadshow this week! ✈️ Monday, ESHG talk on personalized genomes and Robertsonians ✈️ Wednesday, Sanger ToL talk on great ape acrocentric chromosomes 🚂 Thursday, QMUL talk on a little bit of both 🚇 Friday, London reunion with T2T legend @sergeynurk.bsky.social 🎉
For the past 30 years, “whole-genome sequencing” has been a misnomer. Today the T2T Consortium publishes a dozen papers heralding a future of truly complete genomes for humans and nearly any vertebrate 👨🔬🐒🐦🐀🦒🐎🫏🐹🐟 (sorry, no salamanders): www.cell.com/consortium/t... 🧵[1/15]
August 6, 2026 at 3:42 PM
For the past 30 years, “whole-genome sequencing” has been a misnomer. Today the T2T Consortium publishes a dozen papers heralding a future of truly complete genomes for humans and nearly any vertebrate 👨🔬🐒🐦🐀🦒🐎🫏🐹🐟 (sorry, no salamanders): www.cell.com/consortium/t... 🧵[1/15]
Efficient near telomere-to-telomere assembly of Nanopore Simplex reads from @lh3lh3.bsky.social lab www.biorxiv.org/content/10.1...
Efficient near telomere-to-telomere assembly of Nanopore Simplex reads
Telomere-to-telomere (T2T) assembly is the ultimate goal for de novo genome assembly. Existing algorithms capable of near T2T assembly all require Oxford Nanopore Technologies (ONT) ultra-long reads w...
www.biorxiv.org
April 18, 2025 at 10:58 AM
Efficient near telomere-to-telomere assembly of Nanopore Simplex reads from @lh3lh3.bsky.social lab www.biorxiv.org/content/10.1...
T2T zebrafish annotation drop 🐟
Exciting genome news! For those interested, there is a prerelease of the Ensembl gene models for the new reference genomes GRCz12tu (GCA_049306965.1) and GRCz12ab (GCA_05204075.1) at ftp.ebi.ac.uk/pub/database...
You can download gff and gtf files there as well as softmasked genomes.
You can download gff and gtf files there as well as softmasked genomes.
Index of /pub/databases/ensembl/pre-release/Danio_rerio
ftp.ebi.ac.uk
January 13, 2026 at 10:56 PM
T2T zebrafish annotation drop 🐟
A new collection from the T2T Consortium is out in @cp-cell.bsky.social and Cell Genomics — a milestone towards routine “T2T” assembly of any complete, diploid genome.
Explore this exciting work: http://dlvr.it/TTvnWZ
Explore this exciting work: http://dlvr.it/TTvnWZ
August 7, 2026 at 4:16 PM
A new collection from the T2T Consortium is out in @cp-cell.bsky.social and Cell Genomics — a milestone towards routine “T2T” assembly of any complete, diploid genome.
Explore this exciting work: http://dlvr.it/TTvnWZ
Explore this exciting work: http://dlvr.it/TTvnWZ
T2T assemblies for nearly all major Y chromosome haplogroups courtesy of a collab between @humanpangenome.bsky.social and HGSVC! What was once the hardest human chromosome to finish can now be routinely assembled thanks to ONT + Verkko www.biorxiv.org/content/10.6...
June 8, 2026 at 1:42 PM
T2T assemblies for nearly all major Y chromosome haplogroups courtesy of a collab between @humanpangenome.bsky.social and HGSVC! What was once the hardest human chromosome to finish can now be routinely assembled thanks to ONT + Verkko www.biorxiv.org/content/10.6...
La banque UBS condamnée à 75 000 euros d'amende en France pour harcèlement moral envers deux lanceurs d’alerte
➡️ https://l.humanite.fr/T2T
➡️ https://l.humanite.fr/T2T
March 10, 2025 at 4:15 PM
La banque UBS condamnée à 75 000 euros d'amende en France pour harcèlement moral envers deux lanceurs d’alerte
➡️ https://l.humanite.fr/T2T
➡️ https://l.humanite.fr/T2T
Check out our latest work co-led by @dcsoto.bsky.social and @jmuribescr.bsky.social identifying hundreds of human duplicated gene families using the new T2T-CHM13 assembly, with a focus on those potentially contributing to brain evolution 🧪: authors.elsevier.com/a/1lTQtL7PXu...
authors.elsevier.com
July 21, 2025 at 4:26 PM
Check out our latest work co-led by @dcsoto.bsky.social and @jmuribescr.bsky.social identifying hundreds of human duplicated gene families using the new T2T-CHM13 assembly, with a focus on those potentially contributing to brain evolution 🧪: authors.elsevier.com/a/1lTQtL7PXu...
We are excited to officially share the first fully phased telomere-to-telomere (T2T) reference genome for a songbird! 🐦
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
August 6, 2026 at 4:17 PM
We are excited to officially share the first fully phased telomere-to-telomere (T2T) reference genome for a songbird! 🐦
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
Release announcement from T2T consortium!
humanpangenome.org/hprc-data-re...
#ESHG2025. Combining @nanopore @pacbio and @illumina data to improve the T2T pangenome 🧬
humanpangenome.org/hprc-data-re...
#ESHG2025. Combining @nanopore @pacbio and @illumina data to improve the T2T pangenome 🧬
HPRC Data Release 2
HPRC Data Release 2
humanpangenome.org
May 24, 2025 at 12:49 PM
Release announcement from T2T consortium!
humanpangenome.org/hprc-data-re...
#ESHG2025. Combining @nanopore @pacbio and @illumina data to improve the T2T pangenome 🧬
humanpangenome.org/hprc-data-re...
#ESHG2025. Combining @nanopore @pacbio and @illumina data to improve the T2T pangenome 🧬
We welcome you to join us for the T2T Consortium Face-to-Face (T2T-F2F) Meeting in Santa Cruz, CA 9/2-3. Open to all -- register today.🏄♀️
sites.google.com/ucsc.edu/t2t...
sites.google.com/ucsc.edu/t2t...
May 28, 2024 at 6:11 PM
We welcome you to join us for the T2T Consortium Face-to-Face (T2T-F2F) Meeting in Santa Cruz, CA 9/2-3. Open to all -- register today.🏄♀️
sites.google.com/ucsc.edu/t2t...
sites.google.com/ucsc.edu/t2t...
With @burgesslab.bsky.social, not one, but TWO freshly caught T2T zebrafish reference genomes for the Tübingen and AB strains 🎣 🎣 🎉
🎉 Excited to share our new preprint presenting a complete de novo assembly of the zebrafish genome; a major advance for zebrafish genomics and research! 🧬
Full paper: www.biorxiv.org/content/10.1...
@zebrafishrock.bsky.social @izfs.bsky.social @zfinmod.bsky.social @modelzebrafish.bsky.social
Full paper: www.biorxiv.org/content/10.1...
@zebrafishrock.bsky.social @izfs.bsky.social @zfinmod.bsky.social @modelzebrafish.bsky.social
doi.org
November 26, 2025 at 2:51 PM
With @burgesslab.bsky.social, not one, but TWO freshly caught T2T zebrafish reference genomes for the Tübingen and AB strains 🎣 🎣 🎉
Afternoon Richard! Here is my #5albums25
1 Surgeon - Shell~Wave (5pts)
2 Sandwell District - End Beginnings
3 Blawan - SickElixir
4 Cosey Fanni Tutti - t2t
5 Death In Vegas - Death Mask
Wishing you a Happy New Year!
1 Surgeon - Shell~Wave (5pts)
2 Sandwell District - End Beginnings
3 Blawan - SickElixir
4 Cosey Fanni Tutti - t2t
5 Death In Vegas - Death Mask
Wishing you a Happy New Year!
December 29, 2025 at 1:03 PM
Afternoon Richard! Here is my #5albums25
1 Surgeon - Shell~Wave (5pts)
2 Sandwell District - End Beginnings
3 Blawan - SickElixir
4 Cosey Fanni Tutti - t2t
5 Death In Vegas - Death Mask
Wishing you a Happy New Year!
1 Surgeon - Shell~Wave (5pts)
2 Sandwell District - End Beginnings
3 Blawan - SickElixir
4 Cosey Fanni Tutti - t2t
5 Death In Vegas - Death Mask
Wishing you a Happy New Year!
Some #zebrafish news. After consulting with the Genome Reference Consortium (GRC) we will annotate one of our Tübingen T2T assemblies as a reference genome. This is an excellent assembly that we can get into the hands of the zebrafish research community right now. We are continuing our efforts
March 20, 2025 at 8:36 PM
Some #zebrafish news. After consulting with the Genome Reference Consortium (GRC) we will annotate one of our Tübingen T2T assemblies as a reference genome. This is an excellent assembly that we can get into the hands of the zebrafish research community right now. We are continuing our efforts