Drug2Cell

github.com/Teichlab/dru...

Drug target discovery using single-cell/-nucleus transcriptomics data

Parse ChEMBL database (>24 M bioactivity records) into drugs & their targets

Per-cell scoring + Marker enrichment

@teichlab.bsky.social #Nature 2023
www.nature.com/articles/s41...

Gene-level alignment of single-cell trajectories https://www.nature.com/articles/s41592-024-02378-4 Genes2Genes Python pkg: https://github.com/Teichlab/Genes2Genes 🧬🖥️

With TeichLab alumni Dr Jing Su and Prof Joe Marsh in lovely Edinburgh at "hidden cell, dark genome conference"

Today's inspirational role model: Dr Sarah Teichmann @teichlab#WomenInScience #WomensHistoryMonth #womenleaders

sciencemag.org/careers/2015/0…

🏃‍♀️ Congratulations to TeichLab members & friend and colleagues for completing the 5K/10K fun run this weekend at the Cambridge Biomedical Campus, in support of the British Heart Foundation. A fantastic day of community, science, and heart health 💓
#BHF #CambridgeRun #TeamScience #Heart

🆕 journal club by Nick Eagles:

#Bin2cell reconstructs cells from high resolution #VisiumHD data

by Polański #RBartolom et al from #teichlab #YayonNadav labs

📜 doi.org/10.1093/bioi...
🛝 speakerdeck.com/nickeagles/e...
📽️ youtu.be/ZY9N4spEZ_Q