#tjian
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philipcball.bsky.social
Here's an example of the kind of thing I mean. "Tjian tells me that the findings show the pitfalls of ‘reducing an organic system to machine-like parts and assuming that specificity is intrinsic to those parts.’" /4
www.chemistryworld.com/opinion/coll...
Collective interactions dominate gene regulation in eukaryotes
A new technique shows DNA binding domains are not central to transcription factor targeting in human cells, unlike in bacteria
www.chemistryworld.com
September 24, 2026 at 2:55 PM
cangjin.bsky.social
falaram mal dos tjian perto de mim e eu me descontrolei
September 16, 2024 at 2:33 PM
cangjin.bsky.social
sem bot hannigram, sem bot loustat, sem daily peitões do armand, sem flood de tjian na tl... only heaven knows i'm miserable now
September 3, 2024 at 4:15 PM
cangjin.bsky.social
sdds das minhas moots tjian stans do xitter apenas elas entendem meu sofrimento
September 3, 2024 at 3:45 PM
scicommlab.bsky.social
New iBioSeminar by Robert Tjian (HHMI/Berkeley): "The molecular biology of gene regulation" http://www.ibioseminars.org/lectures/bio-mechanisms/robert-tjian.html @HHMINEWS @UCBerkeleyNews
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www.ibioseminars.org
March 7, 2025 at 3:09 AM
rhodamine110.bsky.social
How it started: About eight years ago Bob Tjian ("Tij") and I sat in the back of cab in San Francisco and discussed the crazy idea of using live-cell single-molecule tracking for high-throughput drug screening.

How it's going:
March 28, 2025 at 4:55 PM
chaychayy4.bsky.social
#wetsand #tjian
December 4, 2024 at 3:47 PM
garamandjaehyuk.bsky.social
some people being really weird about the wet sand covers when it’s likely that tjian will get a cover while jo and ian will get another singular cover of their own to reflect the changes in them for s3 if there’s enough chapters to do so… like why be butthurt about the current ones…
February 21, 2025 at 2:43 PM
marcoadriano.bsky.social
omg the vacation tjian art AUGH
November 18, 2024 at 3:57 AM
hdtsh11.bsky.social
"KARAOKE"

#WetSand #TJIAN

feat. www.youtube.com/watch?v=etSb...
KARAOKE It started with the kids. The younger K35 boys were drunk on imported beer and easier nights than they deserved, laughing too loud, singing too badly. The private room was hazy with cigarette smoke, lit in dim purples that caught on glass and sweat and made everyone look softer. Youngwoo had stayed quiet through it all, tucked into the far corner of the couch with a bottle of beer he hadn’t really touched. Not smiling. Not frowning either. Just... absent. “Hyung-nim!” One of them called, grinning as he shoved the mic into his face. “Your turn. We’ve never heard you sing.” “Come on, hyung-nim, just one song!” Another chimed in. “I bet you’ve got some deep, broken-hearted ballad hiding in there.” Taejoon half-expected Youngwoo to brush them off, as he always did. Youngwoo didn’t perform. He barely even spoke unless it was necessary. Not in front of the crew, at least. But this time, he stood. A few of them whooped, thinking they’d won. Someone cued up a bright, sleazy disco track as a joke. But Youngwoo ignored it. He picked up the remote, canceled the song, and typed something in. Taejoon watched the screen light up with the title before the first note even played. Mad World. The Gary Jules version. Slow, stripped down. A funeral dressed as a lullaby. A few of the boys groaned in mock protest. “Seriously?” But the moment Youngwoo opened his mouth, they all fell silent. “All around me are familiar faces— Worn-out places, worn-out faces—” His voice caught everyone off guard. Deep. Resonant. Unguarded. A baritone that clung to the edges of the room and made the walls feel closer. Taejoon felt his own chest go still. He’d heard Youngwoo hum before, in passing. Maybe a note or two in the shower under his breath. But this was different. This was deliberate. A razor turned inward. Youngwoo wasn’t singing to entertain. He wasn’t even really singing to them. He was just letting it out. One verse at a time. “And I find it kind of funny, I find it kind of sad The dreams in which I’m dying are the best I’ve ever had—” Taejoon’s fingers tightened around his glass. He’d noticed things lately. How Youngwoo was sleeping less. Smoking more. How his smiles never reached his eyes anymore. The new silences that followed him everywhere like a second shadow. Taejoon kept thinking it was just fatigue. A bad stretch. Something they'd claw their way out of, like they always did. But this didn’t sound like someone who was tired. It sounded like someone chewing through the bars just to make it stop. And then… Jason. Seated at the back of the room, with one arm draped over the back of the couch, drink resting idle in his hand. Not watching Youngwoo. Watching him. Their eyes locked across the room. Taejoon didn’t move. Didn’t blink. He didn’t need words. Jason’s eyes said enough. It wasn’t a question. It never had been. Normally, Taejoon would’ve looked away. Played dumb. Let the moment pass. But tonight, something in him refused. Maybe it was the song. Maybe it was the crack in Youngwoo’s voice when he hit the line about drowning sorrow. Maybe it was the four beers, or the years of pretending not to care. He held Jason’s gaze and stared back. And for the first time, Jason looked away first. By the time the last note faded, the room felt different. No applause. No teasing. No one quite knew where to look. Youngwoo stepped back from the mic without a word, like it hadn’t meant anything. He returned to his spot, quiet as before. But his eyes found Taejoon’s. For one fleeting second, he smiled. Not the cocky grin he wore when he wanted to piss someone off. Not the mask. This was smaller. Barely there, as if it weren’t meant to last. But it was real. And it was only for him.
July 7, 2025 at 10:09 AM
hdtsh11.bsky.social
"A PERFECT DAY "

wrote this a little while ago, powered entirely by beef soup cravings

#WetSand #TJIAN
June 18, 2025 at 12:57 PM
hdtsh11.bsky.social
Extra Protein

#WetSand #TJIAN NSFW🔞
June 13, 2025 at 11:27 AM
hdtsh11.bsky.social
Dye Job

#WetSand #TJIan
DYE JOB Youngwoo was never one to waste a good cigarette. But when Taejoon showed up at his door, hair bleached to oblivion and grinning like he’d done something brave instead of stupid, the Marlboro Red slipped right from his lips.
 “What the hell did you do to your hair?” “Do you like it?” Taejoon asked, brushing imaginary lint off his collar. “Is this a cry for help? A delayed teenage rebellion?” Taejoon laughed, stepping inside the apartment. “Coming from someone who’s rotated the same three shirts since 2015? Bold.” Closing the door behind him, Youngwooo picked up the fallen cigarette. “At least I’m not out here shining like a beacon in distress.” “Maybe that’s the point. I’m just trying to keep your eyes on me.” “There are easier ways to get my attention. Fewer chemicals involved.” “You haven’t said it looks bad.” Youngwoo let himself be slowly backed into the dining table, Taejoon’s arms bracketing him on either side. He smiled up at Taejoon. “Doesn’t mean I think it looks good.” “You say all that, but you didn’t slam the door in my face.” “Didn’t exactly invite you in, either.” Taejoon looked at him then, the street lights through the window catching in his newly blond hair—stupid and bright. “You never have to ask. Just leave the door unlocked,” he said softly. Youngwoo didn’t answer; he breathed, slow and steady, and leaned in to press his lips against Taejoon’s. When they pulled apart, Youngwoo murmured, “It’s a terrible colour.” Taejoon smiled against his mouth. “You’ll get used to it.”
May 14, 2025 at 7:00 AM
hdtsh11.bsky.social
Thanks for the link! But how about I wait until they reunite before I start 🫢the tjian separation arc is hurting me enough as is
January 12, 2025 at 5:00 AM
hdtsh11.bsky.social
HAPPY NEW YEAR 🎉
Eye of the Beholder is complete!
Hope you enjoy this little gift from me to you, TJIAN nation.
Until Season 3 💜💛

#WetSand
January 2, 2025 at 10:01 AM
hdtsh11.bsky.social
Xmas TJIAN #WetSand

When they were younger, they used to go to the Rockefeller Center to look at the Christmas tree.

It's massive, 75 feet tall, and lit up so brightly you could probably see it from space. There's an ice-skating rink next to it, but since neither of them knew how to skate,
December 25, 2024 at 9:53 AM
hdtsh11.bsky.social
#WetSand #TJIan

He tosses the bag of bloody clothes and shoes to Yangji.

“Burn it. Leave no trace.”

He wedges a chair under the motel's door handle and heads for the bathroom.

He finds him there, huddled under the cold shower, shivering. Without a word, he joins him, sinking beside him
November 25, 2024 at 8:04 AM
hdtsh11.bsky.social
Thank you!! 🫰 Chapter 3 will be out before Christmas 🎄 it’ll be a spicy one, as a present to the tjian community 😈
November 22, 2024 at 7:07 AM
hdtsh11.bsky.social
This is one of my favourite tjian fan art 💛💜
November 18, 2024 at 10:27 AM
hdtsh11.bsky.social
That caption and you tagged it tjian. The AUDACITY 🤭
October 31, 2024 at 11:17 AM
hdtsh11.bsky.social
Did I sign up just for TJIAN angst? Yes I did.

Eye of the Beholder is now on AO3🌟

archiveofourown.org/works/600355...

#WetSand
Eye of the Beholder - Chapter 1 - elioyyy - 웻샌드 | Wet Sand (Webcomic) [Archive of Our Own]
An Archive of Our Own, a project of the Organization for Transformative Works
archiveofourown.org
October 25, 2024 at 9:44 AM
hdtsh11.bsky.social
Contributing to TJIan nation with some angst.

(I don't have an ao3 account so you'll just have to read it on google doc)

tinyurl.com/462j4n9b

#WetSand
Eye of the Beholder
Eye of the Beholder Part One Charles Park fixed the collar of his overcoat one more time, making sure it lay flat on his crisp gray suit before grabbing his briefcase from the backseat of his rented ...
tinyurl.com
October 19, 2024 at 8:21 AM
alexis-verger.cpesr.fr
40 years later, Sp1 has still some secrets to reveal. Thank you M. Tjian 🫡

www.cell.com/fulltext/009...
The promoter-specific transcription factor Sp1 binds to upstream sequences in the SV40 early promoter
Fractionation of HeLa cell extracts reveals the presence of a promoter-specific transcription factor, Sp1, which activates a class of promoters that includes the SV40 early promoter but not several ot...
www.cell.com
April 23, 2026 at 5:41 PM
alexis-verger.cpesr.fr
40 years after the cloning of Sp1, Robert Tjian and coll. discover even more properties

www.science.org/doi/10.1126/...
Unstructured transcription factor interactions enable emergent specificity
How intrinsically disordered regions (IDRs) influence chromatin binding and nuclear organization of transcription factors (TFs) remains unclear. We employed proximity-assisted photoactivation (PAPA), ...
www.science.org
March 20, 2026 at 9:31 AM
bloominglotus01.bsky.social
I have a simpler mind...
Smut sells.
It's a love triangle.
These two important details make me fear that TJIan sex might return in some form.
And it will be a disaster, of course.
joannab3b3.bsky.social joannab3b3.bsky.social @joannab3b3.bsky.social · Oct 23
I dont understand my moots why you all thinking TJ and Ian will have sex when they meet again I mean Ian is already 34 yrs old he knows how Jo really likes him and I dont think he will give him a reason to hurt him 🤷‍♀️ I dont know I just feel there will be no sex between Ian and TJ
October 23, 2024 at 1:17 PM