Out now @nature.com! We report a new means of cell communication: receptor-free signal transduction. TLRs engage MyD88 for minutes, yet myddosomes signal for hours. TRAM releases myddosomes from TLRs, letting them mature and sustain signaling in the cytosol.
rdcu.be/jGdKxErXyAsa
Details below:
rdcu.be/jGdKxErXyAsa
Details below:
September 23, 2026 at 4:29 PM
Out now @nature.com! We report a new means of cell communication: receptor-free signal transduction. TLRs engage MyD88 for minutes, yet myddosomes signal for hours. TRAM releases myddosomes from TLRs, letting them mature and sustain signaling in the cytosol.
rdcu.be/jGdKxErXyAsa
Details below:
rdcu.be/jGdKxErXyAsa
Details below:
The GLP-1 family of drugs have anti-inflammatory effects independent of weight loss.
2 new studies shed light on the mechanisms
—brain-gut-GLP axis blocks inflammation induced by TLRs (toll-like receptor)
www.cell.com/cell-metabol...
2 new studies shed light on the mechanisms
—brain-gut-GLP axis blocks inflammation induced by TLRs (toll-like receptor)
www.cell.com/cell-metabol...
December 27, 2024 at 2:55 PM
The GLP-1 family of drugs have anti-inflammatory effects independent of weight loss.
2 new studies shed light on the mechanisms
—brain-gut-GLP axis blocks inflammation induced by TLRs (toll-like receptor)
www.cell.com/cell-metabol...
2 new studies shed light on the mechanisms
—brain-gut-GLP axis blocks inflammation induced by TLRs (toll-like receptor)
www.cell.com/cell-metabol...
Sunset at Haleakalā tonight
August 6, 2025 at 5:34 AM
Sunset at Haleakalā tonight
Why does RNA undergo glycosylation? Excited to have our paper out. We in collab w/ Ryan Flynn @raflynn5.bsky.social show N-glycans on glycoRNA hide self-RNA from endosomal TLRs promoting silent removal of dead cells. www.nature.com/articles/s41... @uconnresearch.bsky.social @uconnhealth.bsky.social
August 6, 2025 at 3:39 PM
Why does RNA undergo glycosylation? Excited to have our paper out. We in collab w/ Ryan Flynn @raflynn5.bsky.social show N-glycans on glycoRNA hide self-RNA from endosomal TLRs promoting silent removal of dead cells. www.nature.com/articles/s41... @uconnresearch.bsky.social @uconnhealth.bsky.social
For #ForestFriday, this #Landscape shot taken with my #Ricohflex #TLR. I need to take it out more but TLRs are clunky to use...fun but clunky.
📷 Ricohflex TLR
🔘 Rikenon 80mm f/3.5
🎞️ Kodak T-Max 400
#Photography #Scape #EastCoastKin #Monochrome #120film #filmisnotdead #believeinfilm #Ricoh #P482
📷 Ricohflex TLR
🔘 Rikenon 80mm f/3.5
🎞️ Kodak T-Max 400
#Photography #Scape #EastCoastKin #Monochrome #120film #filmisnotdead #believeinfilm #Ricoh #P482
March 20, 2026 at 1:57 PM
For #ForestFriday, this #Landscape shot taken with my #Ricohflex #TLR. I need to take it out more but TLRs are clunky to use...fun but clunky.
📷 Ricohflex TLR
🔘 Rikenon 80mm f/3.5
🎞️ Kodak T-Max 400
#Photography #Scape #EastCoastKin #Monochrome #120film #filmisnotdead #believeinfilm #Ricoh #P482
📷 Ricohflex TLR
🔘 Rikenon 80mm f/3.5
🎞️ Kodak T-Max 400
#Photography #Scape #EastCoastKin #Monochrome #120film #filmisnotdead #believeinfilm #Ricoh #P482
@vijayrathinam.bsky.social @vinnieviruses.bsky.social @raflynn5.bsky.social discovers why RNA undergoes glycosylation: N-glycans on glycoRNAs hide self-RNA from endosomal TLRs promoting ‘silent’ clearance of dead cells @nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
August 6, 2025 at 6:27 PM
@vijayrathinam.bsky.social @vinnieviruses.bsky.social @raflynn5.bsky.social discovers why RNA undergoes glycosylation: N-glycans on glycoRNAs hide self-RNA from endosomal TLRs promoting ‘silent’ clearance of dead cells @nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Me: *has two Yashica TLRs in need of service or repair*
Also me: this one that’s about an hour from where I live looks incredible and I want it
Also me: this one that’s about an hour from where I live looks incredible and I want it
February 28, 2024 at 8:10 PM
Me: *has two Yashica TLRs in need of service or repair*
Also me: this one that’s about an hour from where I live looks incredible and I want it
Also me: this one that’s about an hour from where I live looks incredible and I want it
Normies: TLRs are a pretty small choice for medium format
Me: bet
Me: bet
September 2, 2026 at 6:05 PM
Normies: TLRs are a pretty small choice for medium format
Me: bet
Me: bet
Window display at a camera shop near Cologne Cathedral.
📷Pentax K1000
🎞️Adox HR-50
#filmphotography #blackandwhite #photography #windowdisplay #storedisplay #vintagecameras
📷Pentax K1000
🎞️Adox HR-50
#filmphotography #blackandwhite #photography #windowdisplay #storedisplay #vintagecameras
May 31, 2026 at 9:25 AM
Window display at a camera shop near Cologne Cathedral.
📷Pentax K1000
🎞️Adox HR-50
#filmphotography #blackandwhite #photography #windowdisplay #storedisplay #vintagecameras
📷Pentax K1000
🎞️Adox HR-50
#filmphotography #blackandwhite #photography #windowdisplay #storedisplay #vintagecameras
<laser ranging mentioned> <ears prick up>
TLRS-4, checking in! :)
TLRS-4, checking in! :)
October 31, 2025 at 8:29 PM
<laser ranging mentioned> <ears prick up>
TLRS-4, checking in! :)
TLRS-4, checking in! :)
115. If rangefinders get you laid then TLRs get you rides on those old timey bicycles with the one big wheel in the front.
July 30, 2025 at 2:48 PM
115. If rangefinders get you laid then TLRs get you rides on those old timey bicycles with the one big wheel in the front.
The Mamiya 6 Automat is the camera that keeps me from making another run at TLRs. The 7.5cm, f/3.5 D.Zuiko lens is excellent, and focusing this camera with the rangefinder is a breeze. True the viewfinder isn’t as nice as a big focusing screen, but this thing folds up to fit in a coat pocket.
December 14, 2024 at 9:41 PM
The Mamiya 6 Automat is the camera that keeps me from making another run at TLRs. The 7.5cm, f/3.5 D.Zuiko lens is excellent, and focusing this camera with the rangefinder is a breeze. True the viewfinder isn’t as nice as a big focusing screen, but this thing folds up to fit in a coat pocket.
4/1 "Da sowohl RIG-I als auch TLRs Komponenten von SARS-CoV-2 erkennen, könnte dies zu einer abgeschwächten Entzündungsreaktion auf eine SARS-CoV-2-Reinfektion in den Monaten nach der Erstinfektion führen."
February 9, 2025 at 1:01 PM
4/1 "Da sowohl RIG-I als auch TLRs Komponenten von SARS-CoV-2 erkennen, könnte dies zu einer abgeschwächten Entzündungsreaktion auf eine SARS-CoV-2-Reinfektion in den Monaten nach der Erstinfektion führen."
TLRs must-read books published in 2024!
From romance to thrillers, these sapphic books rocked 2024. Which ones are on your shelf?
@bellabooks.bsky.social
https://buff.ly/4h2eTwI
From romance to thrillers, these sapphic books rocked 2024. Which ones are on your shelf?
@bellabooks.bsky.social
https://buff.ly/4h2eTwI
January 18, 2025 at 2:23 AM
TLRs must-read books published in 2024!
From romance to thrillers, these sapphic books rocked 2024. Which ones are on your shelf?
@bellabooks.bsky.social
https://buff.ly/4h2eTwI
From romance to thrillers, these sapphic books rocked 2024. Which ones are on your shelf?
@bellabooks.bsky.social
https://buff.ly/4h2eTwI
I love my TLRs but the converging lines doesn't always please me. I'll have to go back with the large format or borrow a tilt shift lens. Still Lightroom has helped 'correct' it.
Rolleiflex Automat, Kodak TriX EI 800 developed Bellini Euro HC 1+63
#believeinfilm #filmphotography #kodak #rolleiflex
Rolleiflex Automat, Kodak TriX EI 800 developed Bellini Euro HC 1+63
#believeinfilm #filmphotography #kodak #rolleiflex
December 19, 2023 at 9:18 AM
I love my TLRs but the converging lines doesn't always please me. I'll have to go back with the large format or borrow a tilt shift lens. Still Lightroom has helped 'correct' it.
Rolleiflex Automat, Kodak TriX EI 800 developed Bellini Euro HC 1+63
#believeinfilm #filmphotography #kodak #rolleiflex
Rolleiflex Automat, Kodak TriX EI 800 developed Bellini Euro HC 1+63
#believeinfilm #filmphotography #kodak #rolleiflex
Yashica TLRs are pretty good and not too expensive. We have a Yashica 635 I like it.
December 26, 2024 at 2:18 AM
Yashica TLRs are pretty good and not too expensive. We have a Yashica 635 I like it.
FNS歌謡祭に出ていたHYDEが格好良かった！
勢いで描いてしまった😀
#HYDE
#LArcenCiel
#TLRS
#ラルク
#THELASTROCKSTARS
#人物画
#デジタルイラスト
#絵描きさんと繋がりたい
勢いで描いてしまった😀
#HYDE
#LArcenCiel
#TLRS
#ラルク
#THELASTROCKSTARS
#人物画
#デジタルイラスト
#絵描きさんと繋がりたい
July 3, 2024 at 2:03 PM
FNS歌謡祭に出ていたHYDEが格好良かった！
勢いで描いてしまった😀
#HYDE
#LArcenCiel
#TLRS
#ラルク
#THELASTROCKSTARS
#人物画
#デジタルイラスト
#絵描きさんと繋がりたい
勢いで描いてしまった😀
#HYDE
#LArcenCiel
#TLRS
#ラルク
#THELASTROCKSTARS
#人物画
#デジタルイラスト
#絵描きさんと繋がりたい
Die Daten dieser Studie zeigen eine Toleranz der TLR2-, TLR4- und RIG-I-Aktivierung, die 3-6 Monate nach einer SARS-CoV-2-Infektion bei Personen anhält, die sich von einer leichten oder schweren COVID-19-Infektion erholen. Da sowohl RIG-I als auch TLRs Komponenten von
February 9, 2025 at 11:57 PM
Die Daten dieser Studie zeigen eine Toleranz der TLR2-, TLR4- und RIG-I-Aktivierung, die 3-6 Monate nach einer SARS-CoV-2-Infektion bei Personen anhält, die sich von einer leichten oder schweren COVID-19-Infektion erholen. Da sowohl RIG-I als auch TLRs Komponenten von
Metformin indeed nature’s gift that keeps on giving: mechanism of protection against PM2.5 fine particle pollution www.sciencedirect.com/science/arti...
November 29, 2024 at 10:41 AM
Metformin indeed nature’s gift that keeps on giving: mechanism of protection against PM2.5 fine particle pollution www.sciencedirect.com/science/arti...
Beer For My Horses…Toby Keith and Willie Nelson 🥰💫
Whiskey for my men and beer for my horses….
www.youtube.com/watch?v=TLrs...
Whiskey for my men and beer for my horses….
www.youtube.com/watch?v=TLrs...
Toby Keith W/ Willie Nelson - Beer for my horses (W/Lyrics)
YouTube video by Dylan Coombs
www.youtube.com
June 14, 2026 at 8:10 PM
Beer For My Horses…Toby Keith and Willie Nelson 🥰💫
Whiskey for my men and beer for my horses….
www.youtube.com/watch?v=TLrs...
Whiskey for my men and beer for my horses….
www.youtube.com/watch?v=TLrs...
Klar, bei TLRs geht es nicht anders:
January 12, 2024 at 4:55 PM
Klar, bei TLRs geht es nicht anders:
I'm watching wumpus and woah the marines use TLRs
May 20, 2026 at 1:21 PM
I'm watching wumpus and woah the marines use TLRs