Now online! Reprogrammable RNA-targeting CRISPR systems evolved from RNA toxin-antitoxins
Reprogrammable RNA-targeting CRISPR systems evolved from RNA toxin-antitoxins
Hybrid structure-sequence mining and biochemical/structural characterization trace the evolutionary origins of CRISPR-Cas13, elucidating how their RNA-guided mechanism likely evolved from an ancient scaffold comprising an RNase toxin and an ncRNA…
dlvr.it
February 22, 2025 at 1:47 PM
🦠 The #GmvAT #toxinantitoxin system is important for virulence plasmid maintenance in #Shigella flexneri. In a new article, Wei Xie et al. report the cocrystal structures of GmvT
➡️ doi.org/10.1002/1873-3468.70015
➡️ doi.org/10.1002/1873-3468.70015
March 3, 2025 at 12:00 PM
🦠 The #GmvAT #toxinantitoxin system is important for virulence plasmid maintenance in #Shigella flexneri. In a new article, Wei Xie et al. report the cocrystal structures of GmvT
➡️ doi.org/10.1002/1873-3468.70015
➡️ doi.org/10.1002/1873-3468.70015
Smallest human peered over my shoulder at the weekend when I was checking my first batch of #MicrobesNG sequences, so ofc I walked it all the way back for her, whilst asking what her thoughts were. She immediately grasped #toxinantitoxin and asked if the different types interact. #MolMicro #STEM
November 25, 2024 at 8:30 AM
Smallest human peered over my shoulder at the weekend when I was checking my first batch of #MicrobesNG sequences, so ofc I walked it all the way back for her, whilst asking what her thoughts were. She immediately grasped #toxinantitoxin and asked if the different types interact. #MolMicro #STEM